Bhlha15 (basic helix-loop-helix family, member a15) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Bhlha15 (basic helix-loop-helix family, member a15) Rattus norvegicus
Analyze
Symbol: Bhlha15
Name: basic helix-loop-helix family, member a15
RGD ID: 3091
Description: Enables DNA binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; endoplasmic reticulum unfolded protein response; and negative regulation of myotube differentiation. Predicted to act upstream of or within several processes, including cell-cell adhesion mediated by cadherin; epithelial cell maturation; and intracellular distribution of mitochondria. Located in nucleus. Orthologous to human BHLHA15 (basic helix-loop-helix family member a15); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix transcription factor (bHlH); bHlH; Bhlhb8; class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; MIST-1; Mist1; muscle, intestine and stomach expression 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,534,123 - 15,538,299 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,534,123 - 15,538,515 (-)EnsemblGRCr8
mRatBN7.21210,420,465 - 10,424,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,227,709 - 11,231,885 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,851,005 - 11,855,181 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,874,437 - 10,878,619 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,403,385 - 12,409,103 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,455,040 - 14,459,246 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,747,865 - 10,752,041 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,219,590 - 12,223,766 (-)NCBICelera
RGSC_v3.11210,777,792 - 10,781,969 (-)NCBI
Cytogenetic Map12p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorohydrocarbon  (EXP)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
coumarin  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDD  (ISO)
DDE  (ISO)
DDT  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
endosulfan  (EXP)
endrin  (ISO)
folic acid  (ISO)
furan  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (EXP)
L-methionine  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (EXP)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pioglitazone  (ISO)
pravastatin  (EXP,ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
streptozocin  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP,ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
XL147  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IDA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Butz S, etal., Cell 1998 Sep 18;94(6):773-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Lemercier C, etal., Dev Biol 1997 Feb 1;182(1):101-13.
4. The rat Mist1 gene: structure and promoter characterization. Lemercier C, etal., Gene 2000 Jan 25;242(1-2):209-18.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11696558   PMID:12829745   PMID:12921743   PMID:15024058   PMID:15112319   PMID:15489334   PMID:15665001   PMID:16423820   PMID:17605298   PMID:17612490  


Genomics

Comparative Map Data
Bhlha15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,534,123 - 15,538,299 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,534,123 - 15,538,515 (-)EnsemblGRCr8
mRatBN7.21210,420,465 - 10,424,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,227,709 - 11,231,885 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,851,005 - 11,855,181 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,874,437 - 10,878,619 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,403,385 - 12,409,103 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,455,040 - 14,459,246 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,747,865 - 10,752,041 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,219,590 - 12,223,766 (-)NCBICelera
RGSC_v3.11210,777,792 - 10,781,969 (-)NCBI
Cytogenetic Map12p11NCBI
BHLHA15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38798,211,439 - 98,215,457 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl798,211,439 - 98,215,457 (+)Ensemblhg38GRCh38
GRCh37797,840,751 - 97,844,769 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36797,679,502 - 97,680,207 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34797,486,254 - 97,486,842NCBI
Celera792,535,465 - 92,536,170 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef792,442,435 - 92,443,140 (+)NCBIHuRef
CHM1_1797,771,610 - 97,772,315 (+)NCBICHM1_1
T2T-CHM13v2.0799,441,577 - 99,445,595 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2797,166,444 - 97,167,149 (+)NCBI
Bhlha15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395144,127,104 - 144,131,259 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5144,127,104 - 144,131,259 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385144,190,286 - 144,194,441 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5144,190,286 - 144,194,441 (+)Ensemblmm10GRCm38
MGSCv375144,951,155 - 144,955,310 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365144,443,813 - 144,447,968 (+)NCBIMGSCv36mm8
Celera5141,174,663 - 141,178,820 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map583.05NCBI
Bhlha15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546014,103,053 - 14,106,714 (+)Ensembl
ChiLan1.0NW_00495546014,103,053 - 14,106,714 (+)NCBIChiLan1.0ChiLan1.0
BHLHA15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26116,057,828 - 116,061,791 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17164,322,479 - 164,326,423 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v076,306,929 - 6,311,026 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17103,676,211 - 103,680,153 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7103,677,022 - 103,677,593 (+)EnsemblpanPan2panpan1.1
BHLHA15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1611,112,233 - 11,115,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl611,114,694 - 11,115,257 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha612,738,597 - 12,742,381 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0611,112,675 - 11,116,461 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1610,981,367 - 10,985,151 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0610,961,184 - 10,964,967 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0611,195,228 - 11,199,013 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bhlha15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344139,188,655 - 139,192,549 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936750753,615 - 754,187 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936750752,887 - 756,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BHLHA15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl35,410,518 - 5,414,072 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.135,410,467 - 5,414,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.235,464,958 - 5,473,366 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BHLHA15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12814,953,483 - 14,957,674 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2814,956,095 - 14,956,679 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660701,119,815 - 1,123,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bhlha15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474031,672,397 - 31,674,205 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474031,671,820 - 31,676,045 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Bhlha15
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1168,996,946 - 9,001,101 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bhlha15
19 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:226
Interacting mature miRNAs:283
Transcripts:ENSRNOT00000037251
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)121186960016966542Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
D12Wox29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,426,000 - 10,426,267 (+)MAPPERmRatBN7.2
mRatBN7.21210,426,164 - 10,426,267 (+)MAPPERmRatBN7.2
Rnor_6.01212,409,085 - 12,409,366NCBIRnor6.0
Rnor_6.01212,409,266 - 12,409,366NCBIRnor6.0
Rnor_5.01214,460,921 - 14,461,021UniSTSRnor5.0
Rnor_5.01214,460,740 - 14,461,021UniSTSRnor5.0
RGSC_v3.41210,753,565 - 10,753,665UniSTSRGSC3.4
Celera1212,225,290 - 12,225,388UniSTS
Cytogenetic Map12p11UniSTS
D12Wox19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,423,273 - 10,423,429 (+)MAPPERmRatBN7.2
Rnor_6.01212,406,194 - 12,406,349NCBIRnor6.0
Rnor_5.01214,457,849 - 14,458,004UniSTSRnor5.0
RGSC_v3.41210,750,674 - 10,750,829UniSTSRGSC3.4
Celera1212,222,399 - 12,222,554UniSTS
Cytogenetic Map12p11UniSTS
D12Wox20  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81215,536,039 - 15,536,327 (+)Marker Load Pipeline
mRatBN7.21210,422,381 - 10,422,669 (+)MAPPERmRatBN7.2
Rnor_6.01212,405,302 - 12,405,589NCBIRnor6.0
Rnor_5.01214,456,957 - 14,457,244UniSTSRnor5.0
RGSC_v3.41210,749,782 - 10,750,069UniSTSRGSC3.4
Celera1212,221,507 - 12,221,794UniSTS
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 55 142 91 90 59 86 59 6 323 172 11 117 68 90 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000037251   ⟹   ENSRNOP00000035219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,534,123 - 15,538,515 (-)Ensembl
mRatBN7.2 Ensembl1210,420,467 - 10,424,713 (-)Ensembl
Rnor_6.0 Ensembl1212,403,385 - 12,407,561 (-)Ensembl
RefSeq Acc Id: NM_012863   ⟹   NP_036995
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,534,123 - 15,538,299 (-)NCBI
mRatBN7.21210,420,465 - 10,424,641 (-)NCBI
Rnor_6.01212,403,385 - 12,407,561 (-)NCBI
Rnor_5.01214,455,040 - 14,459,246 (-)NCBI
RGSC_v3.41210,747,865 - 10,752,041 (-)RGD
Celera1212,219,590 - 12,223,766 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_036995 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53111 (Get FASTA)   NCBI Sequence Viewer  
  AAF17707 (Get FASTA)   NCBI Sequence Viewer  
  AAH61868 (Get FASTA)   NCBI Sequence Viewer  
  EDL89638 (Get FASTA)   NCBI Sequence Viewer  
  P70562 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036995   ⟸   NM_012863
- UniProtKB: P70562 (UniProtKB/Swiss-Prot),   A6K1I0 (UniProtKB/TrEMBL),   A0A8L2QJ40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035219   ⟸   ENSRNOT00000037251
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70562-F1-model_v2 AlphaFold P70562 1-197 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698427
Promoter ID:EPDNEW_R8952
Type:initiation region
Name:Bhlha15_1
Description:basic helix-loop-helix family, member a15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01212,407,519 - 12,407,579EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3091 AgrOrtholog
BioCyc Gene G2FUF-20031 BioCyc
Ensembl Genes ENSRNOG00000025164 Ensembl
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598799 IMAGE-MGC_LOAD
InterPro bHLH_dom UniProtKB/Swiss-Prot
  bHLH_transcription_factors UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:25334 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72528 IMAGE-MGC_LOAD
NCBI Gene 25334 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED UniProtKB/Swiss-Prot
  CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 UniProtKB/Swiss-Prot
Pfam HLH UniProtKB/Swiss-Prot
PhenoGen Bhlha15 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000025164 RatGTEx
SMART HLH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot
TIGR TC222251
UniProt A0A8L2QJ40 ENTREZGENE, UniProtKB/TrEMBL
  A6K1I0 ENTREZGENE, UniProtKB/TrEMBL
  BHA15_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-19 Bhlha15  basic helix-loop-helix family, member a15  Bhlhb8  basic helix-loop-helix domain containing, class B, 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Bhlhb8  basic helix-loop-helix domain containing, class B, 8  Mist1  muscle, intestine and stomach expression 1  Symbol and Name updated 1299863 APPROVED
2002-06-10 Mist1  Basic helix-loop-helix transcription factor (bHlH)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to the DNA target sequence -CANNTG- (E-box) 633179
gene_product member of basic helix-loop-helix transcription factor family 633179