Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gucy1b1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GUCY1B1 mRNA | CTD | PMID:22206623 | Gucy1b1 | Rat | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of GUCY1B1 mRNA | CTD | PMID:15212814 | Gucy1b1 | Rat | 17beta-estradiol | affects expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Estradiol affects the expression of GUCY1B1 mRNA | CTD | PMID:16684588 | Gucy1b1 | Rat | 17beta-estradiol | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of GUCY1B1 mRNA | CTD | PMID:30165855 | Gucy1b1 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol deficiency results in decreased expression of GUCY1B1 mRNA and Estradiol deficiency results in decreased expression of GUCY1B1 protein | CTD | PMID:18787021 | Gucy1b1 | Rat | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | multiple interactions | EXP | | 6480464 | 1H-(1 more ... | CTD | PMID:12495780 more ... | Gucy1b1 | Rat | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | increases degradation | EXP | | 6480464 | 1H-(1 more ... | CTD | PMID:19466990 | Gucy1b1 | Rat | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 1H-(1 more ... | CTD | PMID:11744065 and PMID:22171090 | Gucy1b1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Gucy1b1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GUCY1B1 mRNA | CTD | PMID:22298810 | Gucy1b1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GUCY1B1 mRNA | CTD | PMID:32109520 and PMID:34747641 | Gucy1b1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GUCY1B1 mRNA | CTD | PMID:28213091 | Gucy1b1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | Gucy1b1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Gucy1b1 | Rat | 3',5'-cyclic GMP | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [GUCY1A1 protein binds to GUCY1B1 protein] which results in increased chemical synthesis of Cyclic GMP | CTD | PMID:22171090 | Gucy1b1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GUCY1B1 mRNA | CTD | PMID:16054899 | Gucy1b1 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of GUCY1B1 mRNA | CTD | PMID:30723492 | Gucy1b1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of GUCY1B3 mRNA | CTD | PMID:30951980 | Gucy1b1 | Rat | 5-fluorouracil | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Fluorouracil results in decreased expression of GUCY1B1 mRNA | CTD | PMID:19219653 | Gucy1b1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of GUCY1B1 mRNA | CTD | PMID:36843608 | Gucy1b1 | Rat | 7H-xanthine | multiple interactions | EXP | | 6480464 | [Xanthine co-treated with XDH protein] results in decreased expression of GUCY1B1 protein | CTD | PMID:17339839 | Gucy1b1 | Rat | 9H-xanthine | multiple interactions | EXP | | 6480464 | [Xanthine co-treated with XDH protein] results in decreased expression of GUCY1B1 protein | CTD | PMID:17339839 | Gucy1b1 | Rat | aconitine | increases expression | EXP | | 6480464 | Aconitine results in increased expression of GUCY1B1 protein | CTD | PMID:33236894 | Gucy1b1 | Rat | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of GUCY1B1 protein | CTD | PMID:19903525 | Gucy1b1 | Rat | all-trans-retinoic acid | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GUCY1B1 mRNA | CTD | PMID:23724009 | Gucy1b1 | Rat | amiodarone | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of GUCY1B1 mRNA | CTD | PMID:19774075 | Gucy1b1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GUCY1B1 mRNA | CTD | PMID:16483693 | Gucy1b1 | Rat | ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of GUCY1B1 mRNA | CTD | PMID:16517024 | Gucy1b1 | Rat | ammonium chloride | decreases expression | EXP | | 6480464 | Ammonium Chloride results in decreased expression of GUCY1B1 mRNA and Ammonium Chloride results in decreased expression of GUCY1B1 protein | CTD | PMID:16517024 | Gucy1b1 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of GUCY1B1 mRNA | CTD | PMID:30779732 | Gucy1b1 | Rat | antirheumatic drug | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of GUCY1B1 mRNA | CTD | PMID:24449571 | Gucy1b1 | Rat | apocynin | increases expression | EXP | | 6480464 | acetovanillone results in increased expression of GUCY1B1 protein | CTD | PMID:25217652 | Gucy1b1 | Rat | benzene | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Benzene results in increased expression of GUCY1B3 mRNA | CTD | PMID:34624356 | Gucy1b1 | Rat | benzo[a]pyrene | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of GUCY1B1 mRNA | CTD | PMID:22228805 | Gucy1b1 | Rat | benzo[a]pyrene | increases methylation | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GUCY1B3 exon and Benzo(a)pyrene results in increased methylation of GUCY1B3 promoter | CTD | PMID:27901495 | Gucy1b1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Gucy1b1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of GUCY1B3 mRNA | CTD | PMID:31163220 | Gucy1b1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of GUCY1B1 mRNA | CTD | PMID:25181051 | Gucy1b1 | Rat | bisphenol A | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GUCY1B1 protein | CTD | PMID:31675489 | Gucy1b1 | Rat | bisphenol A | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of GUCY1B3 mRNA | CTD | PMID:30951980 | Gucy1b1 | Rat | bisphenol A | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of GUCY1B1 mRNA | CTD | PMID:27685785 and PMID:29275510 | Gucy1b1 | Rat | bisphenol F | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of GUCY1B3 mRNA | CTD | PMID:30951980 | Gucy1b1 | Rat | BQ 123 | multiple interactions | EXP | | 6480464 | cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] | CTD | PMID:16395254 | Gucy1b1 | Rat | butanal | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of GUCY1B1 mRNA | CTD | PMID:26079696 | Gucy1b1 | Rat | cadmium dichloride | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of GUCY1B1 mRNA | CTD | PMID:12160620 | Gucy1b1 | Rat | cadmium dichloride | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of GUCY1B3 mRNA | CTD | PMID:38382870 | Gucy1b1 | Rat | carbon nanotube | decreases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of GUCY1B1 mRNA | CTD | PMID:25620056 | Gucy1b1 | Rat | CGP 52608 | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GUCY1B1 gene] | CTD | PMID:28238834 | Gucy1b1 | Rat | cinaciguat | multiple interactions | EXP | | 6480464 | 1H-(1 more ... | CTD | PMID:19466990 | Gucy1b1 | Rat | cinaciguat | affects binding | EXP | | 6480464 | BAY 58-2667 binds to GUCY1B1 protein | CTD | PMID:19466990 | Gucy1b1 | Rat | cinaciguat | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [BAY 58-2667 co-treated with 1H-(1 more ... | CTD | PMID:22171090 | Gucy1b1 | Rat | cisplatin | affects response to substance | ISO | GUCY1B1 (Homo sapiens) | 6480464 | GUCY1B1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Gucy1b1 | Rat | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of GUCY1B1 mRNA | CTD | PMID:17898221 | Gucy1b1 | Rat | cyanocob(III)alamin | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3 more ... | CTD | PMID:22171090 | Gucy1b1 | Rat | dexamethasone | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GUCY1B1 mRNA | CTD | PMID:16054899 | Gucy1b1 | Rat | dibutyl phthalate | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of GUCY1B1 mRNA | CTD | PMID:17361019 and PMID:21266533 | Gucy1b1 | Rat | diethyl malate | affects expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | diethyl malate affects the expression of GUCY1B1 mRNA | CTD | PMID:24814887 | Gucy1b1 | Rat | dorsomorphin | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GUCY1B1 mRNA | CTD | PMID:27188386 | Gucy1b1 | Rat | doxorubicin | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of GUCY1B1 mRNA | CTD | PMID:29803840 | Gucy1b1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of GUCY1B3 mRNA | CTD | PMID:31464424 | Gucy1b1 | Rat | entinostat | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of GUCY1B1 mRNA | CTD | PMID:26272509 | Gucy1b1 | Rat | entinostat | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GUCY1B1 mRNA | CTD | PMID:27188386 | Gucy1b1 | Rat | ethanol | increases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Ethanol results in increased expression of GUCY1B1 mRNA | CTD | PMID:30319688 | Gucy1b1 | Rat | ethanol | affects splicing | ISO | Gucy1b1 (Mus musculus) | 6480464 | Ethanol affects the splicing of GUCY1B1 mRNA | CTD | PMID:30319688 | Gucy1b1 | Rat | ferroheme b | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Polysorbates inhibits the reaction [Heme binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | ferroheme b | multiple interactions | EXP | | 6480464 | 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] more ... | CTD | PMID:19466990 | Gucy1b1 | Rat | folic acid | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GUCY1B1 mRNA | CTD | PMID:22206623 | Gucy1b1 | Rat | formaldehyde | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of GUCY1B1 mRNA | CTD | PMID:27664576 | Gucy1b1 | Rat | glyphosate | decreases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of GUCY1B1 mRNA | CTD | PMID:35897073 | Gucy1b1 | Rat | GTP | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [dicyanocobinamide results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] which results in increased metabolism of Guanosine Triphosphate | CTD | PMID:22171090 | Gucy1b1 | Rat | heme b | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Polysorbates inhibits the reaction [Heme binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | heme b | multiple interactions | EXP | | 6480464 | 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] more ... | CTD | PMID:19466990 | Gucy1b1 | Rat | hydrogen peroxide | decreases expression | EXP | | 6480464 | Hydrogen Peroxide results in decreased expression of GUCY1B1 protein | CTD | PMID:17339839 | Gucy1b1 | Rat | hydroquinone | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | hydroquinone results in increased expression of GUCY1B1 mRNA | CTD | PMID:31256213 | Gucy1b1 | Rat | hydroxocobalamin | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Hydroxocobalamin results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | indinavir | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA | CTD | PMID:16931933 | Gucy1b1 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of GUCY1B1 mRNA | CTD | PMID:20080153 | Gucy1b1 | Rat | L-ascorbic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] | CTD | PMID:11729227 | Gucy1b1 | Rat | lamivudine | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA more ... | CTD | PMID:16931933 | Gucy1b1 | Rat | lead diacetate | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] and cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] | CTD | PMID:11729227 and PMID:16395254 | Gucy1b1 | Rat | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of GUCY1B1 mRNA and lead acetate results in decreased expression of GUCY1B1 protein | CTD | PMID:11729227 and PMID:16395254 | Gucy1b1 | Rat | lipopolysaccharide | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | ESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1B1 mRNA] and ESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1B1 protein] | CTD | PMID:17158209 | Gucy1b1 | Rat | lipopolysaccharide | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of GUCY1B1 mRNA | CTD | PMID:35811015 | Gucy1b1 | Rat | lipopolysaccharide | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of GUCY1B1 mRNA] | CTD | PMID:35811015 | Gucy1b1 | Rat | manganese atom | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Manganese results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | manganese(0) | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Manganese results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | menadione | decreases expression | EXP | | 6480464 | Vitamin K 3 results in decreased expression of GUCY1B1 protein | CTD | PMID:17339839 | Gucy1b1 | Rat | methotrexate | affects expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Methotrexate affects the expression of GUCY1B1 mRNA | CTD | PMID:18502557 | Gucy1b1 | Rat | methylmercury chloride | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of GUCY1B1 mRNA | CTD | PMID:28001369 | Gucy1b1 | Rat | mitoxantrone | affects response to substance | ISO | GUCY1B1 (Homo sapiens) | 6480464 | GUCY1B1 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | Gucy1b1 | Rat | nitric oxide | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 1H-(1 more ... | CTD | PMID:11744065 | Gucy1b1 | Rat | nitroglycerin | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Nitroglycerin results in increased expression of GUCY1B1 protein | CTD | PMID:11742226 | Gucy1b1 | Rat | nitroglycerin | increases expression | EXP | | 6480464 | Nitroglycerin results in increased expression of GUCY1B1 mRNA and Nitroglycerin results in increased expression of GUCY1B1 protein | CTD | PMID:11331261 and PMID:17541025 | Gucy1b1 | Rat | nitroprusside | multiple interactions | EXP | | 6480464 | 1H-(1 more ... | CTD | PMID:12495780 and PMID:17050951 | Gucy1b1 | Rat | NONOate(1-) | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | 1 more ... | CTD | PMID:22171090 | Gucy1b1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of GUCY1B1 mRNA | CTD | PMID:25729387 | Gucy1b1 | Rat | ozone | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of GUCY1B1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of GUCY1B1 mRNA | CTD | PMID:34911549 | Gucy1b1 | Rat | paracetamol | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of GUCY1B1 mRNA | CTD | PMID:26690555 | Gucy1b1 | Rat | pentanal | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | pentanal results in increased expression of GUCY1B1 mRNA | CTD | PMID:26079696 | Gucy1b1 | Rat | phenobarbital | affects expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of GUCY1B1 mRNA | CTD | PMID:23091169 | Gucy1b1 | Rat | potassium hexacyanoferrate(3-) | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | potassium ferricyanide inhibits the reaction [1 and 1-diethyl-2-hydroxy-2-nitrosohydrazine results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] | CTD | PMID:22171090 | Gucy1b1 | Rat | propanal | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of GUCY1B1 mRNA | CTD | PMID:26079696 | Gucy1b1 | Rat | protoporphyrin | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Polysorbates promotes the reaction [protoporphyrin IX results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] and protoporphyrin IX results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein] | CTD | PMID:22171090 | Gucy1b1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of GUCY1B1 mRNA] | CTD | PMID:35811015 | Gucy1b1 | Rat | saquinavir | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA | CTD | PMID:16931933 | Gucy1b1 | Rat | SB 431542 | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GUCY1B1 mRNA | CTD | PMID:27188386 | Gucy1b1 | Rat | silicon dioxide | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of GUCY1B1 mRNA | CTD | PMID:25351596 | Gucy1b1 | Rat | sodium arsenite | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of GUCY1B1 mRNA | CTD | PMID:38568856 | Gucy1b1 | Rat | succimer | multiple interactions | ISO | GUCY1B1 (Homo sapiens) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of GUCY1B1 mRNA | CTD | PMID:26378955 | Gucy1b1 | Rat | sunitinib | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of GUCY1B1 mRNA | CTD | PMID:31533062 | Gucy1b1 | Rat | titanium dioxide | decreases expression | ISO | Gucy1b1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of GUCY1B1 mRNA | CTD | PMID:23557971 | Gucy1b1 | Rat | titanium dioxide | increases methylation | ISO | GUCY1B1 (Homo sapiens) | 6480464 | titanium dioxide results in increased methylation of GUCY1B3 gene | CTD | PMID:34973136 | Gucy1b1 | Rat | toluene | affects expression | EXP | | 6480464 | Toluene affects the expression of GUCY1B1 mRNA | CTD | PMID:21827849 | Gucy1b1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of GUCY1B1 mRNA | CTD | PMID:25729387 | Gucy1b1 | Rat | trichostatin A | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of GUCY1B1 mRNA | CTD | PMID:24935251 | Gucy1b1 | Rat | triphenyl phosphate | affects expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GUCY1B1 mRNA | CTD | PMID:37042841 | Gucy1b1 | Rat | valproic acid | affects expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GUCY1B1 mRNA | CTD | PMID:25979313 | Gucy1b1 | Rat | valproic acid | increases methylation | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of GUCY1B1 gene | CTD | PMID:29154799 | Gucy1b1 | Rat | valproic acid | increases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GUCY1B1 mRNA | CTD | PMID:19101580 more ... | Gucy1b1 | Rat | vorinostat | decreases expression | ISO | GUCY1B1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of GUCY1B1 mRNA | CTD | PMID:18769122 | Gucy1b1 | Rat | zidovudine | multiple interactions | ISO | Gucy1b1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA more ... | CTD | PMID:16931933 | Gucy1b1 | Rat | zinc protoporphyrin | multiple interactions | EXP | | 6480464 | zinc protoporphyrin inhibits the reaction [5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]] more ... | CTD | PMID:19466990 | |