Galr1 (galanin receptor 1) - Rat Genome Database

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Gene: Galr1 (galanin receptor 1) Rattus norvegicus
Analyze
Symbol: Galr1
Name: galanin receptor 1
RGD ID: 2656
Description: Enables galanin receptor activity and neuropeptide binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in nicotine dependence; opiate dependence; and opioid abuse. Orthologous to human GALR1 (galanin receptor 1); INTERACTS WITH 2-deoxy-D-glucose; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GAL1-R; galanin receptor type 1; Galnr1; GALR-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81878,046,803 - 78,062,359 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1878,046,805 - 78,062,359 (-)EnsemblGRCr8
mRatBN7.21875,772,021 - 75,787,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1875,772,023 - 75,787,577 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1877,873,305 - 77,888,899 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01878,543,582 - 78,559,170 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01876,391,102 - 76,406,704 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01879,243,009 - 79,258,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1879,243,009 - 79,258,570 (-)Ensemblrn6Rnor6.0
Rnor_5.01878,302,017 - 78,317,578 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41878,858,892 - 78,874,451 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1874,409,272 - 74,424,831 (-)NCBICelera
RGSC_v3.11878,941,425 - 78,947,496 (-)NCBI
RH 3.4 Map18809.9RGD
Cytogenetic Map18q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Galanin enhances corticosterone secretion from dispersed rat adrenocortical cells through the activation of GAL-R1 and GAL-R2 receptors coupled to the adenylate cyclase-dependent signaling cascade. Andreis PG, etal., Int J Mol Med. 2007 Jan;19(1):149-55.
2. Two genes in the rat homologous to human NKG2. Berg SF, etal., Eur J Immunol 1998 Feb;28(2):444-50
3. Elevated expression of galanin receptors in childhood neuroblastic tumors. Berger A, etal., Neuroendocrinology 2002 Feb;75(2):130-8.
4. Expression of GalR1 and GalR2 galanin receptor messenger ribonucleic acid in proopiomelanocortin neurons of the rat arcuate nucleus: effect of testosterone. Bouret S, etal., Endocrinology 2000 May;141(5):1780-94
5. Cloning, pharmacological characterization, and anatomical distribution of a rat cDNA encoding for a galanin receptor. Burgevin MC, etal., J Mol Neurosci 1995;6(1):33-41.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
9. Drug addiction and stress-response genetic variability: association study in African Americans. Levran O, etal., Ann Hum Genet. 2014 Jul;78(4):290-8. doi: 10.1111/ahg.12064. Epub 2014 Apr 26.
10. The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment. Lori A, etal., Neuropsychopharmacology. 2011 Jun;36(7):1412-20. doi: 10.1038/npp.2011.25. Epub 2011 Mar 23.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area. Moreno E, etal., J Neurosci. 2017 Feb 1;37(5):1176-1186. doi: 10.1523/JNEUROSCI.2442-16.2016. Epub 2016 Dec 22.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Cloning and characterization of the rat GALR1 galanin receptor from Rin14B insulinoma cells. Parker EM, etal., Brain Res Mol Brain Res 1995 Dec 28;34(2):179-89.
15. Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence. Randesi M, etal., Pharmacogenomics. 2020 Aug;21(13):903-917. doi: 10.2217/pgs-2020-0045. Epub 2020 Aug 6.
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Human galanin (GAL) and galanin 1 receptor (GALR1) variations are not involved in fat intake and early onset obesity. Schauble N, etal., J Nutr. 2005 Jun;135(6):1387-92.
20. Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover. Smith KE, etal., J Biol Chem 1997 Sep 26;272(39):24612-6.
21. Expression of galanin receptor-1 (GALR1) in the rat trigeminal ganglia and molar teeth. Suzuki H, etal., Neurosci Res 2002 Mar;42(3):197-207.
22. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
23. Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes. Wang S, etal., Biochemistry. 1998 May 12;37(19):6711-7.
24. Upregulation of galanin binding sites and GalR1 mRNA levels in the mouse locus coeruleus following chronic morphine treatments and precipitated morphine withdrawal. Zachariou V, etal., Neuropsychopharmacology. 2000 Aug;23(2):127-37. doi: 10.1016/S0893-133X(00)00094-4.
25. The role of galanin system in modulating depression, anxiety, and addiction-like behaviors after chronic restraint stress. Zhao X, etal., Neuroscience. 2013 Aug 29;246:82-93. doi: 10.1016/j.neuroscience.2013.04.046. Epub 2013 Apr 30.
Additional References at PubMed
PMID:14623054   PMID:14764000   PMID:15885774   PMID:15944003   PMID:15944004   PMID:16626647   PMID:17982695   PMID:18172432   PMID:19006083   PMID:21593325   PMID:21880366   PMID:21894515  
PMID:22197078   PMID:24517231   PMID:24614744   PMID:27041232   PMID:27127795   PMID:27457954   PMID:28062253   PMID:29127424   PMID:29852172   PMID:34086200   PMID:34108238  


Genomics

Comparative Map Data
Galr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81878,046,803 - 78,062,359 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1878,046,805 - 78,062,359 (-)EnsemblGRCr8
mRatBN7.21875,772,021 - 75,787,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1875,772,023 - 75,787,577 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1877,873,305 - 77,888,899 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01878,543,582 - 78,559,170 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01876,391,102 - 76,406,704 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01879,243,009 - 79,258,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1879,243,009 - 79,258,570 (-)Ensemblrn6Rnor6.0
Rnor_5.01878,302,017 - 78,317,578 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41878,858,892 - 78,874,451 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1874,409,272 - 74,424,831 (-)NCBICelera
RGSC_v3.11878,941,425 - 78,947,496 (-)NCBI
RH 3.4 Map18809.9RGD
Cytogenetic Map18q12.3NCBI
GALR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381877,249,848 - 77,277,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1877,249,848 - 77,277,900 (+)Ensemblhg38GRCh38
GRCh371874,961,804 - 74,989,856 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361873,090,721 - 73,111,081 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341873,090,720 - 73,111,081NCBI
Celera1871,781,397 - 71,801,439 (+)NCBICelera
Cytogenetic Map18q23NCBI
HuRef1871,642,787 - 71,663,380 (+)NCBIHuRef
CHM1_11874,958,364 - 74,978,152 (+)NCBICHM1_1
T2T-CHM13v2.01877,480,984 - 77,510,848 (+)NCBIT2T-CHM13v2.0
Galr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391882,410,621 - 82,424,902 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1882,410,505 - 82,424,902 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381882,392,496 - 82,406,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1882,392,380 - 82,406,777 (-)Ensemblmm10GRCm38
MGSCv371882,561,888 - 82,576,169 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361882,527,838 - 82,541,229 (-)NCBIMGSCv36mm8
Celera1883,464,283 - 83,478,564 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1855.78NCBI
Galr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540260,546,186 - 60,559,298 (+)Ensembl
ChiLan1.0NW_00495540260,449,660 - 60,559,549 (+)NCBIChiLan1.0ChiLan1.0
GALR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21794,795,870 - 94,824,732 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11880,488,494 - 80,516,608 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01870,643,718 - 70,664,068 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11873,899,995 - 73,917,849 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1873,899,995 - 73,917,752 (+)EnsemblpanPan2panpan1.1
GALR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112,750,117 - 2,785,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12,729,331 - 2,742,231 (-)EnsemblcanFam3CanFam3.1
CanFam3.1 Ensembl12,729,331 - 2,742,231 (-)NCBIcanFam3CanFam3.1
Dog10K_Boxer_Tasha13,728,748 - 3,802,391 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.012,528,062 - 2,601,762 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12,532,833 - 2,548,666 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112,573,436 - 2,647,073 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012,523,851 - 2,597,515 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012,694,052 - 2,767,702 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Galr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494416,679,669 - 16,700,474 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366162,007,352 - 2,020,737 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366162,007,339 - 2,020,737 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GALR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,443,821 - 147,463,542 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11147,442,977 - 147,466,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21162,977,166 - 162,994,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GALR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1182,719,736 - 2,739,018 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606023,243,960 - 23,263,451 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Galr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248063,334,325 - 3,347,087 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248063,331,025 - 3,347,774 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Galr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11549,910,860 - 49,926,676 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Galr1
58 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:867
Count of miRNA genes:300
Interacting mature miRNAs:396
Transcripts:ENSRNOT00000022335, ENSRNOT00000022401
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
634333Pia19Pristane induced arthritis QTL 193.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)187627210481806852Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat

Markers in Region
D18Chm74  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21875,781,593 - 75,781,783 (+)MAPPERmRatBN7.2
Rnor_6.01879,252,584 - 79,252,773NCBIRnor6.0
Rnor_5.01878,311,592 - 78,311,781UniSTSRnor5.0
RGSC_v3.41878,868,465 - 78,868,654UniSTSRGSC3.4
Celera1874,418,845 - 74,419,034UniSTS
Cytogenetic Map18q12.3UniSTS
D18Chm73  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21875,778,396 - 75,778,588 (+)MAPPERmRatBN7.2
Rnor_6.01879,249,385 - 79,249,576NCBIRnor6.0
Rnor_5.01878,308,393 - 78,308,584UniSTSRnor5.0
RGSC_v3.41878,865,268 - 78,865,459UniSTSRGSC3.4
Celera1874,415,648 - 74,415,839UniSTS
Cytogenetic Map18q12.3UniSTS
RH94734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21875,773,094 - 75,773,219 (+)MAPPERmRatBN7.2
Rnor_6.01879,244,083 - 79,244,207NCBIRnor6.0
Rnor_5.01878,303,091 - 78,303,215UniSTSRnor5.0
RGSC_v3.41878,859,966 - 78,860,090UniSTSRGSC3.4
Celera1874,410,346 - 74,410,470UniSTS
RH 3.4 Map18809.9UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 4 101 16 19 4 11 4 1 53 16 100 22 32 15 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000022401   ⟹   ENSRNOP00000022400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1878,046,805 - 78,062,359 (-)Ensembl
mRatBN7.2 Ensembl1875,772,023 - 75,787,577 (-)Ensembl
Rnor_6.0 Ensembl1879,243,009 - 79,258,570 (-)Ensembl
RefSeq Acc Id: NM_012958   ⟹   NP_037090
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81878,046,803 - 78,062,359 (-)NCBI
mRatBN7.21875,772,021 - 75,787,577 (-)NCBI
Rnor_6.01879,243,009 - 79,258,570 (-)NCBI
Rnor_5.01878,302,017 - 78,317,578 (-)NCBI
RGSC_v3.41878,858,892 - 78,874,451 (-)RGD
Celera1874,409,272 - 74,424,831 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037090 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA99741 (Get FASTA)   NCBI Sequence Viewer  
  AAC52438 (Get FASTA)   NCBI Sequence Viewer  
  EDL75210 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022400
  ENSRNOP00000022400.1
GenBank Protein Q62805 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037090   ⟸   NM_012958
- UniProtKB: Q62805 (UniProtKB/Swiss-Prot),   A6K5J0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022400   ⟸   ENSRNOT00000022401
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62805-F1-model_v2 AlphaFold Q62805 1-346 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2656 AgrOrtholog
BioCyc Gene G2FUF-6798 BioCyc
Ensembl Genes ENSRNOG00000016654 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022401 ENTREZGENE
  ENSRNOT00000022401.3 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GAL1_rcpt UniProtKB/Swiss-Prot
  Galanin_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:50577 UniProtKB/Swiss-Prot
NCBI Gene 50577 ENTREZGENE
PANTHER GALANIN RECEPTOR 1 UniProtKB/Swiss-Prot
  LEUCOKININ RECEPTOR-RELATED UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Galr1 PhenoGen
PRINTS GALANIN1R UniProtKB/Swiss-Prot
  GALANINR UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016654 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
TIGR TC215478
UniProt A6K5J0 ENTREZGENE, UniProtKB/TrEMBL
  GALR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Galr1  galanin receptor 1      Symbol and Name status set to approved 70586 APPROVED
2000-11-11 Galr1  Galanin Receptor 1      Symbol updated 61033 APPROVED
2000-11-11 Galnr1  Galanin Receptor 1      Symbol withdrawn 61033 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_expression expressed by most POMC (precursor molecule for the opioid peptide beta-endorphin) neurons in rostral parts of the nucleus 61034
gene_expression expressed by most POMC (precursor molecule for the opioid peptide beta-endorphin) neurons in rostral parts of the nucleus 61084
gene_function receptor for neuropeptide galanin 61034
gene_function receptor for neuropeptide galanin 61084
gene_process involved in the control of pituitary functions and feeding behavior and in modulating POMC neuron activity 61034
gene_process involved in the control of pituitary functions and feeding behavior and in modulating POMC neuron activity 61084
gene_regulation expression modulated by testosterone 61034
gene_regulation expression modulated by testosterone 61084