Emp1 (epithelial membrane protein 1) - Rat Genome Database

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Gene: Emp1 (epithelial membrane protein 1) Rattus norvegicus
Analyze
Symbol: Emp1
Name: epithelial membrane protein 1
RGD ID: 2552
Description: Predicted to be involved in apoptotic process and bleb assembly. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human EMP1 (epithelial membrane protein 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CL-20; EMP-1; ENP1MR; MGC93627; TMP; tumor-associated membrane protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84169,931,537 - 169,964,366 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4169,931,440 - 169,964,365 (+)EnsemblGRCr8
mRatBN7.24168,212,901 - 168,233,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4168,212,861 - 168,232,904 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4174,508,148 - 174,528,283 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04170,289,375 - 170,309,512 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04168,913,787 - 168,933,886 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04169,161,076 - 169,181,967 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4169,147,243 - 169,181,966 (+)Ensemblrn6Rnor6.0
Rnor_5.04233,429,622 - 233,449,799 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44172,315,122 - 172,335,536 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4156,809,308 - 156,829,662 (+)NCBICelera
RGSC_v3.14172,560,057 - 172,580,471 (+)NCBI
RH 3.4 Map41027.2RGD
Cytogenetic Map4q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
aristolochic acids  (EXP)
Aroclor 1254  (ISO)
Azaspiracid  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzoates  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
choline  (ISO)
ciglitazone  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (EXP)
dinophysistoxin 1  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
etoposide  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
graphite  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP)
methylparaben  (ISO)
monosodium L-glutamate  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nicotine  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paclitaxel  (EXP)
panobinostat  (ISO)
paracetamol  (EXP)
PD 0325901  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family. Chen Y, etal., Genomics 1997 Apr 1;41(1):40-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family. Taylor V, etal., J Biol Chem 1995 Dec 1;270(48):28824-33.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:12107182   PMID:12477932   PMID:15489334   PMID:16036215  


Genomics

Comparative Map Data
Emp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84169,931,537 - 169,964,366 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4169,931,440 - 169,964,365 (+)EnsemblGRCr8
mRatBN7.24168,212,901 - 168,233,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4168,212,861 - 168,232,904 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4174,508,148 - 174,528,283 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04170,289,375 - 170,309,512 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04168,913,787 - 168,933,886 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04169,161,076 - 169,181,967 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4169,147,243 - 169,181,966 (+)Ensemblrn6Rnor6.0
Rnor_5.04233,429,622 - 233,449,799 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44172,315,122 - 172,335,536 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4156,809,308 - 156,829,662 (+)NCBICelera
RGSC_v3.14172,560,057 - 172,580,471 (+)NCBI
RH 3.4 Map41027.2RGD
Cytogenetic Map4q43NCBI
EMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381213,196,726 - 13,219,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1213,196,723 - 13,219,941 (+)Ensemblhg38GRCh38
GRCh371213,349,660 - 13,372,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361213,240,924 - 13,260,975 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341213,240,923 - 13,260,974NCBI
Celera1218,498,531 - 18,518,631 (+)NCBICelera
Cytogenetic Map12p13.1NCBI
HuRef1213,119,788 - 13,139,888 (+)NCBIHuRef
CHM1_11213,315,034 - 13,335,140 (+)NCBICHM1_1
T2T-CHM13v2.01213,071,022 - 13,094,235 (+)NCBIT2T-CHM13v2.0
Emp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396135,339,548 - 135,360,171 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6135,339,543 - 135,360,171 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm386135,362,550 - 135,383,173 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6135,362,545 - 135,383,173 (+)Ensemblmm10GRCm38
MGSCv376135,312,949 - 135,333,191 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366135,328,624 - 135,348,866 (+)NCBIMGSCv36mm8
Celera6138,310,329 - 138,330,705 (+)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.25NCBI
Emp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541310,062,635 - 10,081,733 (+)Ensembl
ChiLan1.0NW_00495541310,062,621 - 10,081,551 (+)NCBIChiLan1.0ChiLan1.0
EMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21018,651,626 - 18,672,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11218,648,742 - 18,668,787 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1213,610,060 - 13,630,819 (+)EnsemblpanPan2panpan1.1
EMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12733,177,874 - 33,199,048 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2733,179,576 - 33,206,634 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2713,244,920 - 13,265,394 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02733,485,048 - 33,505,550 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2733,460,262 - 33,505,508 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12733,379,102 - 33,399,580 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02733,328,579 - 33,349,072 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02712,980,813 - 13,001,316 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Emp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494594,376,839 - 94,380,834 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365874,104,679 - 4,108,448 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365874,104,414 - 4,108,446 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl559,244,691 - 59,268,025 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1559,245,317 - 59,267,466 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11113,099,213 - 13,119,492 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1113,114,132 - 13,119,541 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606922,199,349 - 22,219,618 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475224,780,689 - 24,797,544 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475224,778,610 - 24,797,395 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Emp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1614,043,337 - 14,063,107 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Emp1
190 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:417
Count of miRNA genes:233
Interacting mature miRNAs:287
Transcripts:ENSRNOT00000011580
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
RH142452  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map41027.2UniSTS
Cytogenetic Map4q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000011580   ⟹   ENSRNOP00000011580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4169,943,958 - 169,964,364 (+)Ensembl
mRatBN7.2 Ensembl4168,212,861 - 168,232,904 (+)Ensembl
Rnor_6.0 Ensembl4169,147,243 - 169,181,966 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079785   ⟹   ENSRNOP00000070837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4169,161,585 - 169,179,783 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118837   ⟹   ENSRNOP00000081339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4169,931,440 - 169,964,365 (+)Ensembl
mRatBN7.2 Ensembl4168,226,859 - 168,232,904 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000136832   ⟹   ENSRNOP00000106602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4169,943,958 - 169,963,577 (+)Ensembl
RefSeq Acc Id: NM_012843   ⟹   NP_036975
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84169,944,230 - 169,964,366 (+)NCBI
mRatBN7.24168,212,901 - 168,233,039 (+)NCBI
Rnor_6.04169,161,628 - 169,181,967 (+)NCBI
Rnor_5.04233,429,622 - 233,449,799 (+)NCBI
RGSC_v3.44172,315,122 - 172,335,536 (+)RGD
Celera4156,809,308 - 156,829,662 (+)RGD
Sequence:
RefSeq Acc Id: XM_063285588   ⟹   XP_063141658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84169,931,562 - 169,964,366 (+)NCBI
RefSeq Acc Id: XM_063285589   ⟹   XP_063141659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84169,931,561 - 169,964,366 (+)NCBI
RefSeq Acc Id: XM_063285590   ⟹   XP_063141660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84169,931,537 - 169,964,366 (+)NCBI
RefSeq Acc Id: NP_036975   ⟸   NM_012843
- UniProtKB: P54848 (UniProtKB/Swiss-Prot),   A6IMG6 (UniProtKB/TrEMBL),   A0A8I5ZRF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070837   ⟸   ENSRNOT00000079785
Ensembl Acc Id: ENSRNOP00000011580   ⟸   ENSRNOT00000011580
Ensembl Acc Id: ENSRNOP00000081339   ⟸   ENSRNOT00000118837
RefSeq Acc Id: XP_063141660   ⟸   XM_063285590
- Peptide Label: isoform X1
- UniProtKB: P54848 (UniProtKB/Swiss-Prot),   A0A8I5ZRF3 (UniProtKB/TrEMBL),   A6IMG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141659   ⟸   XM_063285589
- Peptide Label: isoform X1
- UniProtKB: P54848 (UniProtKB/Swiss-Prot),   A0A8I5ZRF3 (UniProtKB/TrEMBL),   A6IMG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141658   ⟸   XM_063285588
- Peptide Label: isoform X1
- UniProtKB: P54848 (UniProtKB/Swiss-Prot),   A0A8I5ZRF3 (UniProtKB/TrEMBL),   A6IMG6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106602   ⟸   ENSRNOT00000136832

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54848-F1-model_v2 AlphaFold P54848 1-160 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693464
Promoter ID:EPDNEW_R3986
Type:initiation region
Name:Emp1_1
Description:epithelial membrane protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04169,161,648 - 169,161,708EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2552 AgrOrtholog
BioCyc Gene G2FUF-42628 BioCyc
Ensembl Genes ENSRNOG00000008676 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011580 ENTREZGENE
  ENSRNOT00000011580.7 UniProtKB/Swiss-Prot
  ENSRNOT00000118837 ENTREZGENE
Gene3D-CATH 1.20.140.150 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192247 IMAGE-MGC_LOAD
InterPro EMP_1 UniProtKB/Swiss-Prot
  PMP-22/EMP/MP20 UniProtKB/Swiss-Prot
  PMP22/EMP/MP20/Claudin UniProtKB/Swiss-Prot
  PMP22_EMP_MP20 UniProtKB/Swiss-Prot
KEGG Report rno:25314 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93627 IMAGE-MGC_LOAD
NCBI Gene 25314 ENTREZGENE
PANTHER EPITHELIAL MEMBRANE PROTEIN-RELATED UniProtKB/Swiss-Prot
  PTHR10671:SF6 UniProtKB/Swiss-Prot
Pfam PMP22_Claudin UniProtKB/Swiss-Prot
PhenoGen Emp1 PhenoGen
PRINTS EPMEMFAMILY UniProtKB/Swiss-Prot
  EPMEMPROT1 UniProtKB/Swiss-Prot
PROSITE PMP22_1 UniProtKB/Swiss-Prot
  PMP22_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008676 RatGTEx
TIGR TC237563
UniProt A0A8I5ZRF3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M005_RAT UniProtKB/TrEMBL
  A6IMG6 ENTREZGENE, UniProtKB/TrEMBL
  EMP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Emp1  Epithelial membrane protein 1      Symbol and Name status set to approved 70586 APPROVED