Kank2 (KN motif and ankyrin repeat domains 2) - Rat Genome Database

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Gene: Kank2 (KN motif and ankyrin repeat domains 2) Rattus norvegicus
Analyze
Symbol: Kank2
Name: KN motif and ankyrin repeat domains 2
RGD ID: 2320289
Description: Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; podocyte cell migration; and regulation of intracellular signal transduction. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16 and palmoplantar keratoderma and woolly hair. Orthologous to human KANK2 (KN motif and ankyrin repeat domains 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KN motif and ankyrin repeat domain-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2-like; LOC100361376; rCG31687-like; RGD1563532
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,587,770 - 28,617,212 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl828,587,770 - 28,616,993 (-)EnsemblGRCr8
mRatBN7.2820,311,676 - 20,341,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,311,676 - 20,340,900 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx824,347,039 - 24,376,370 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0822,642,587 - 22,671,915 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0820,541,282 - 20,570,501 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,792,000 - 22,821,459 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,791,995 - 22,821,397 (-)Ensemblrn6Rnor6.0
Rnor_5.0822,846,154 - 22,875,574 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4820,865,615 - 20,892,573 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera821,702,311 - 21,731,556 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (EXP)
gentamycin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
methimazole  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (ISO)
organophosphorus compound  (EXP)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
mitochondrion  (IEA,ISO)

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. Gee HY, etal., J Clin Invest. 2015 Jun;125(6):2375-84. doi: 10.1172/JCI79504. Epub 2015 May 11.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17476305   PMID:22371500   PMID:24671081   PMID:32544715   PMID:32570033   PMID:33450132  


Genomics

Comparative Map Data
Kank2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,587,770 - 28,617,212 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl828,587,770 - 28,616,993 (-)EnsemblGRCr8
mRatBN7.2820,311,676 - 20,341,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,311,676 - 20,340,900 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx824,347,039 - 24,376,370 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0822,642,587 - 22,671,915 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0820,541,282 - 20,570,501 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,792,000 - 22,821,459 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,791,995 - 22,821,397 (-)Ensemblrn6Rnor6.0
Rnor_5.0822,846,154 - 22,875,574 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4820,865,615 - 20,892,573 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera821,702,311 - 21,731,556 (-)NCBICelera
Cytogenetic Map8q13NCBI
KANK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,164,270 - 11,197,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1911,164,267 - 11,197,945 (-)Ensemblhg38GRCh38
GRCh371911,274,946 - 11,308,541 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,135,946 - 11,167,496 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341911,135,946 - 11,167,496NCBI
Celera1911,169,761 - 11,203,056 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,851,580 - 10,884,321 (-)NCBIHuRef
CHM1_11911,276,193 - 11,309,454 (-)NCBICHM1_1
T2T-CHM13v2.01911,291,296 - 11,324,866 (-)NCBIT2T-CHM13v2.0
Kank2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,678,069 - 21,709,842 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl921,678,080 - 21,710,040 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38921,766,773 - 21,798,546 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,766,784 - 21,798,744 (-)Ensemblmm10GRCm38
MGSCv37921,571,217 - 21,602,990 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36921,518,479 - 21,548,919 (-)NCBIMGSCv36mm8
Celera919,036,363 - 19,068,137 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.88NCBI
Kank2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554952,168,992 - 2,173,581 (-)NCBIChiLan1.0ChiLan1.0
KANK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22016,080,285 - 16,113,351 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11915,078,983 - 15,111,807 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01910,713,582 - 10,746,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11911,426,149 - 11,457,376 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1911,426,149 - 11,457,359 (-)EnsemblpanPan2panpan1.1
KANK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,067,749 - 50,093,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,067,760 - 50,091,320 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2049,941,266 - 49,966,898 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02050,588,664 - 50,614,343 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2050,588,642 - 50,614,335 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,798,849 - 49,824,490 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,225,723 - 50,251,351 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02050,468,431 - 50,494,081 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kank2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,015,097 - 209,034,537 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,321,980 - 1,337,746 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,320,169 - 1,340,137 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KANK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,896,120 - 69,924,919 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1269,896,116 - 69,925,194 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KANK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1610,095,319 - 10,131,985 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl610,095,246 - 10,131,946 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660749,755,298 - 9,792,353 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kank2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,041,991 - 3,062,113 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248283,039,871 - 3,060,329 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Kank2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1818,036,999 - 18,062,553 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kank2
204 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:160
Count of miRNA genes:117
Interacting mature miRNAs:126
Transcripts:ENSRNOT00000014135, ENSRNOT00000045488
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
RH130874  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2820,315,153 - 20,315,354 (+)MAPPERmRatBN7.2
Rnor_6.0822,795,478 - 22,795,678NCBIRnor6.0
Rnor_5.0822,849,632 - 22,849,832UniSTSRnor5.0
RGSC_v3.4820,869,104 - 20,869,304UniSTSRGSC3.4
Celera821,705,789 - 21,705,989UniSTS
RH133408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2820,311,770 - 20,311,971 (+)MAPPERmRatBN7.2
Rnor_6.0822,792,095 - 22,792,295NCBIRnor6.0
Rnor_5.0822,846,249 - 22,846,449UniSTSRnor5.0
RGSC_v3.4820,865,710 - 20,865,910UniSTSRGSC3.4
Celera821,702,406 - 21,702,606UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 87 59 6 351 187 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014135   ⟹   ENSRNOP00000014135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl828,587,770 - 28,616,993 (-)Ensembl
mRatBN7.2 Ensembl820,311,676 - 20,340,900 (-)Ensembl
Rnor_6.0 Ensembl822,792,000 - 22,821,223 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000045488   ⟹   ENSRNOP00000048736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl828,587,770 - 28,616,993 (-)Ensembl
mRatBN7.2 Ensembl820,312,245 - 20,339,532 (-)Ensembl
Rnor_6.0 Ensembl822,791,995 - 22,821,397 (-)Ensembl
RefSeq Acc Id: NM_001270413   ⟹   NP_001257342
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,587,770 - 28,616,993 (-)NCBI
mRatBN7.2820,311,676 - 20,340,900 (-)NCBI
Rnor_6.0822,792,000 - 22,821,223 (-)NCBI
Rnor_5.0822,846,154 - 22,875,574 (-)NCBI
Celera821,702,311 - 21,731,556 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242589   ⟹   XP_006242651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,587,771 - 28,617,212 (-)NCBI
mRatBN7.2820,311,676 - 20,341,107 (-)NCBI
Rnor_6.0822,792,001 - 22,821,459 (-)NCBI
Rnor_5.0822,846,154 - 22,875,574 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242590   ⟹   XP_006242652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,587,771 - 28,617,203 (-)NCBI
mRatBN7.2820,311,676 - 20,341,107 (-)NCBI
Rnor_6.0822,792,001 - 22,821,459 (-)NCBI
Rnor_5.0822,846,154 - 22,875,574 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063264709   ⟹   XP_063120779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,587,771 - 28,617,195 (-)NCBI
RefSeq Acc Id: NP_001257342   ⟸   NM_001270413
- UniProtKB: D4ACC2 (UniProtKB/TrEMBL),   A6JNU5 (UniProtKB/TrEMBL),   A0A8L2QNK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242652   ⟸   XM_006242590
- Peptide Label: isoform X1
- UniProtKB: D3ZD05 (UniProtKB/TrEMBL),   A0A8L2QNK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242651   ⟸   XM_006242589
- Peptide Label: isoform X1
- UniProtKB: D3ZD05 (UniProtKB/TrEMBL),   A0A8L2QNK4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048736   ⟸   ENSRNOT00000045488
Ensembl Acc Id: ENSRNOP00000014135   ⟸   ENSRNOT00000014135
RefSeq Acc Id: XP_063120779   ⟸   XM_063264709
- Peptide Label: isoform X1
- UniProtKB: D3ZD05 (UniProtKB/Swiss-Prot),   A0A8L2QNK4 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZD05-F1-model_v2 AlphaFold D3ZD05 1-847 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695789
Promoter ID:EPDNEW_R6313
Type:multiple initiation site
Name:Kank2_1
Description:KN motif and ankyrin repeat domains 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0822,821,177 - 22,821,237EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320289 AgrOrtholog
BioCyc Gene G2FUF-31409 BioCyc
Ensembl Genes ENSRNOG00000010643 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014135 ENTREZGENE
  ENSRNOT00000014135.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  KANK1-4 UniProtKB/Swiss-Prot
  KN_motif UniProtKB/Swiss-Prot
NCBI Gene 100361376 ENTREZGENE
PANTHER KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
Pfam Ank UniProtKB/Swiss-Prot
  Ank_2 UniProtKB/Swiss-Prot
  KN_motif UniProtKB/Swiss-Prot
PhenoGen Kank2 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010643 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot
UniProt A0A8L2QNK4 ENTREZGENE, UniProtKB/TrEMBL
  A6JNU5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZD05 ENTREZGENE
  D4ACC2 ENTREZGENE, UniProtKB/TrEMBL
  KANK2_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-10 Kank2  KN motif and ankyrin repeat domains 2  LOC100361376  rCG31687-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-02 LOC100361376  rCG31687-like  RGD1563532  similar to ankyrin repeat domain 25  Data merged from RGD:1563532 1643240 APPROVED
2010-05-05 LOC100361376  rCG31687-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1563532  similar to ankyrin repeat domain 25   RGD1563532_predicted  similar to ankyrin repeat domain 25 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563532_predicted  similar to ankyrin repeat domain 25 (predicted)  LOC300439  similar to ankyrin repeat domain 25  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC300439  similar to ankyrin repeat domain 25      Symbol and Name status set to provisional 70820 PROVISIONAL