Ca5a (carbonic anhydrase 5A) - Rat Genome Database

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Gene: Ca5a (carbonic anhydrase 5A) Rattus norvegicus
Analyze
Symbol: Ca5a (Ensembl: Car5a)
Name: carbonic anhydrase 5A
RGD ID: 2243
Description: Enables carbonate dehydratase activity. Predicted to be active in mitochondrion. Orthologous to human CA5A (carbonic anhydrase 5A); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CA-VA; Ca5; Car5a; carbonate dehydratase VA; carbonic anhydrase 5; carbonic anhydrase 5 mitochondrial; carbonic anhydrase 5, mitochondrial; carbonic anhydrase 5a, mitochondrial; carbonic anhydrase Va, mitochondrial; MGC108708
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,881,678 - 66,911,486 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1966,881,693 - 66,911,486 (-)EnsemblGRCr8
mRatBN7.21949,973,092 - 50,002,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,973,107 - 50,002,906 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1956,765,427 - 56,795,202 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,448,040 - 57,477,851 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,664,027 - 59,693,795 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,731,829 - 54,761,697 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1954,731,859 - 54,761,670 (-)Ensemblrn6Rnor6.0
Rnor_5.01965,451,126 - 65,480,815 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,158,607 - 52,188,664 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,218,046 - 49,247,995 (-)NCBICelera
RGSC_v3.11952,163,493 - 52,193,545 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetazolamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
carbonates  (ISO)
chloric acid  (ISO)
chlorpyrifos  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dibenzofurans  (ISO)
dimethyl sulfoxide  (ISO)
diquat  (ISO)
epoxiconazole  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
methapyrilene  (ISO)
methimazole  (EXP)
molybdate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nitric acid  (ISO)
okadaic acid  (ISO)
oryzalin  (ISO)
paracetamol  (ISO)
perchlorate  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
propofol  (ISO)
rotenone  (EXP)
senecionine  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sulfamic acid  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP)
tungstate  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Mitochondrial carbonic anhydrase (isozyme V) in mouse and rat: cDNA cloning, expression, subcellular localization, processing, and tissue distribution. Nagao Y, etal., Proc Natl Acad Sci U S A 1994 Oct 25;91(22):10330-4.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7929150   PMID:10677517   PMID:12477932   PMID:14600151   PMID:14651853   PMID:15489334   PMID:18614015  


Genomics

Comparative Map Data
Ca5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,881,678 - 66,911,486 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1966,881,693 - 66,911,486 (-)EnsemblGRCr8
mRatBN7.21949,973,092 - 50,002,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,973,107 - 50,002,906 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1956,765,427 - 56,795,202 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,448,040 - 57,477,851 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,664,027 - 59,693,795 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,731,829 - 54,761,697 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1954,731,859 - 54,761,670 (-)Ensemblrn6Rnor6.0
Rnor_5.01965,451,126 - 65,480,815 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,158,607 - 52,188,664 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,218,046 - 49,247,995 (-)NCBICelera
RGSC_v3.11952,163,493 - 52,193,545 (-)NCBI
Cytogenetic Map19q12NCBI
CA5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381687,881,549 - 87,936,529 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1687,881,546 - 87,936,580 (-)Ensemblhg38GRCh38
GRCh371687,915,155 - 87,970,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361686,479,126 - 86,527,613 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341686,479,125 - 86,527,613NCBI
Celera1672,219,173 - 72,267,375 (-)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1673,662,132 - 73,710,650 (-)NCBIHuRef
CHM1_11689,333,043 - 89,381,480 (-)NCBICHM1_1
T2T-CHM13v2.01693,954,203 - 94,009,111 (-)NCBIT2T-CHM13v2.0
Car5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,642,874 - 122,671,651 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8122,642,865 - 122,671,643 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388121,916,135 - 121,944,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,916,126 - 121,944,904 (-)Ensemblmm10GRCm38
MGSCv378124,440,035 - 124,468,812 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368121,987,915 - 122,017,051 (-)NCBIMGSCv36mm8
MGSCv368124,802,236 - 124,830,994 (-)NCBIMGSCv36mm8
Celera8126,138,230 - 126,172,629 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.81NCBI
Ca5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,139,920 - 2,160,597 (-)Ensembl
ChiLan1.0NW_0049555412,141,450 - 2,159,955 (-)NCBIChiLan1.0ChiLan1.0
CA5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21897,653,307 - 97,706,766 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116103,574,183 - 103,588,635 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01668,564,400 - 68,618,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11687,887,288 - 87,903,159 (-)NCBIPanPan1.1PanPan1.1panPan2
CA5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,269,855 - 65,297,593 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,269,635 - 65,296,777 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha565,280,118 - 65,307,768 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0565,489,652 - 65,517,389 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl565,489,538 - 65,516,573 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1565,515,185 - 65,542,854 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0565,346,901 - 65,374,559 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,753,935 - 65,781,642 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ca5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,719,672 - 25,742,042 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,480,325 - 1,495,490 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,478,285 - 1,495,490 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,506,042 - 1,538,777 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.161,495,615 - 1,539,390 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CA5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1573,284,536 - 73,333,629 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660472,374,418 - 2,429,386 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ca5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247461,293,875 - 1,315,890 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247461,293,619 - 1,323,067 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ca5a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11741,560,357 - 41,589,343 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:39
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000025848
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
D19Rat21  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81966,885,065 - 66,885,203 (+)Marker Load Pipeline
mRatBN7.21949,976,481 - 49,976,619 (+)MAPPERmRatBN7.2
Rnor_6.01954,735,217 - 54,735,354NCBIRnor6.0
Rnor_5.01965,454,505 - 65,454,642UniSTSRnor5.0
RGSC_v3.41952,161,991 - 52,162,128UniSTSRGSC3.4
RGSC_v3.41952,161,990 - 52,162,128RGDRGSC3.4
Celera1949,221,436 - 49,221,573UniSTS
RGSC_v3.11952,166,872 - 52,167,009RGD
RH 3.4 Map19682.9RGD
RH 3.4 Map19682.9UniSTS
RH 2.0 Map19661.4RGD
Cytogenetic Map19q12UniSTS
AU048492  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21949,995,987 - 49,996,107 (+)MAPPERmRatBN7.2
Rnor_6.01954,754,723 - 54,754,842NCBIRnor6.0
Rnor_5.01965,474,033 - 65,474,152UniSTSRnor5.0
RGSC_v3.41952,181,788 - 52,181,907UniSTSRGSC3.4
Celera1949,241,081 - 49,241,200UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 10 32 113 91 90 59 26 59 6 203 80 93 47 59 31 7 7

Sequence


Ensembl Acc Id: ENSRNOT00000025848   ⟹   ENSRNOP00000025848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1966,881,693 - 66,911,486 (-)Ensembl
mRatBN7.2 Ensembl1949,973,107 - 50,002,906 (-)Ensembl
Rnor_6.0 Ensembl1954,731,859 - 54,761,670 (-)Ensembl
RefSeq Acc Id: NM_019293   ⟹   NP_062166
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81966,881,678 - 66,911,486 (-)NCBI
mRatBN7.21949,973,092 - 50,002,906 (-)NCBI
Rnor_6.01954,731,829 - 54,761,637 (-)NCBI
Rnor_5.01965,451,126 - 65,480,815 (-)NCBI
RGSC_v3.41952,158,607 - 52,188,664 (-)RGD
Celera1949,218,046 - 49,247,995 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_062166 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA50832 (Get FASTA)   NCBI Sequence Viewer  
  AAH88147 (Get FASTA)   NCBI Sequence Viewer  
  EDL92734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025848
  ENSRNOP00000025848.2
GenBank Protein P43165 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062166   ⟸   NM_019293
- Peptide Label: precursor
- UniProtKB: P43165 (UniProtKB/Swiss-Prot),   A6IZQ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025848   ⟸   ENSRNOT00000025848
Protein Domains
Alpha-carbonic anhydrase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P43165-F1-model_v2 AlphaFold P43165 1-304 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701202
Promoter ID:EPDNEW_R11724
Type:multiple initiation site
Name:Ca5a_1
Description:carbonic anhydrase 5A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01954,761,641 - 54,761,701EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2243 AgrOrtholog
BioCyc Gene G2FUF-5409 BioCyc
Ensembl Genes ENSRNOG00000019098 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025848 ENTREZGENE
  ENSRNOT00000025848.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7323596 IMAGE-MGC_LOAD
InterPro CA_dom UniProtKB/Swiss-Prot
  CA_dom_sf UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class_CS UniProtKB/Swiss-Prot
KEGG Report rno:54233 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108708 IMAGE-MGC_LOAD
NCBI Gene 54233 ENTREZGENE
PANTHER CARBONIC ANHYDRASE 5A, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR18952 UniProtKB/Swiss-Prot
Pfam Carb_anhydrase UniProtKB/Swiss-Prot
PhenoGen Ca5a PhenoGen
PROSITE ALPHA_CA_1 UniProtKB/Swiss-Prot
  ALPHA_CA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019098 RatGTEx
SMART Carb_anhydrase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot
UniProt A6IZQ6 ENTREZGENE, UniProtKB/TrEMBL
  CAH5A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-04-28 Ca5a  carbonic anhydrase 5A  Car5a  carbonic anhydrase 5A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-04-18 Car5a  carbonic anhydrase 5A  Ca5a  carbonic anhydrase 5A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-04-16 Ca5a  carbonic anhydrase 5A  Car5a  carbonic anhydrase 5A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-03-16 Car5a  carbonic anhydrase 5A  Ca5a  carbonic anhydrase 5A  Symbol changed 629549 APPROVED
2016-05-20 Ca5a  carbonic anhydrase 5A  Car5a  carbonic anhydrase 5A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-18 Car5a  carbonic anhydrase 5A  Car5a  carbonic anhydrase 5a, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-20 Car5a  carbonic anhydrase 5a, mitochondrial  Ca5a  carbonic anhydrase Va, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Ca5a  carbonic anhydrase Va, mitochondrial  Ca5a  carbonic anhydrase 5a, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ca5a  carbonic anhydrase 5a, mitochondrial    carbonic anhydrase 5  Name updated 1299863 APPROVED
2002-06-10 Ca5a  carbonic anhydrase 5      Name updated 70584 APPROVED
2001-12-10 Ca5a  carbonic anhydrase 5, mitochondrial      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to mitochondria 69789
gene_process may be involved in gluconeogenesis and ureagenesis 69789