Adcyap1r1 (ADCYAP receptor type I) - Rat Genome Database

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Pathways
Gene: Adcyap1r1 (ADCYAP receptor type I) Rattus norvegicus
Analyze
Symbol: Adcyap1r1
Name: ADCYAP receptor type I
RGD ID: 2038
Description: Enables adenylate cyclase binding activity; neuropeptide binding activity; and small GTPase binding activity. Involved in several processes, including cAMP/PKA signal transduction; positive regulation of inositol phosphate biosynthetic process; and positive regulation of intracellular signal transduction. Located in several cellular components, including bicellular tight junction; caveola; and cell surface. Biomarker of cystitis. Orthologous to human ADCYAP1R1 (ADCYAP receptor type I); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADCYAP receptor type 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 receptor 1; adenylate cyclase activating polypeptide 1 receptor type 1; adenylate cyclase activating polypeptide 1 type 1 receptor; PAC1-R; PACAP type I receptor; PACAP type IA receptor; PACAP-R-1; PACAP-R-1A; PACAP-R1; PACAP-R1A; PACAPR1; PACAPR1A; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase-activating polypeptide type I receptor; pituitary adenylate cyclase-activating polypeptide type IA receptor; rat pituitary adenylate cyclase activating polypeptide 1 receptor (1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,924,171 - 85,972,973 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl485,924,100 - 85,972,973 (+)EnsemblGRCr8
mRatBN7.2484,593,558 - 84,642,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx489,816,241 - 89,865,223 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0485,591,645 - 85,640,627 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,997,328 - 84,046,283 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,662,809 - 85,711,696 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensemblrn6Rnor6.0
Rnor_5.04150,314,846 - 150,363,650 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4484,209,729 - 84,254,982 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera479,461,538 - 79,510,340 (+)NCBICelera
RGSC_v3.1484,478,820 - 84,501,994 (+)NCBI
Cytogenetic Map4q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) in the cochlea: evidence for specific transcript expression of PAC1-R splice variants in rat microdissected cochlear subfractions. Abu-Hamdan MD, etal., Neuroscience. 2006 Jun 19;140(1):147-61. Epub 2006 Apr 19.
2. PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Apostolakis EM, etal., Mol Endocrinol. 2005 Nov;19(11):2798-811. Epub 2005 Jun 23.
3. Molecular cloning of a novel variant of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor that stimulates calcium influx by activation of L-type calcium channels. Chatterjee TK, etal., J Biol Chem. 1996 Dec 13;271(50):32226-32.
4. Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea. Drescher MJ, etal., Neuroscience. 2006 Sep 29;142(1):139-64. Epub 2006 Jul 31.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis. Girard BM, etal., J Mol Neurosci. 2008 Nov;36(1-3):310-20. Epub 2008 Jun 19.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior. Hammack SE, etal., Psychoneuroendocrinology. 2009 Jul;34(6):833-43. Epub 2009 Jan 31.
9. Decrease of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in rat testes by ethanol exposure. Koh PO and Won CK, J Vet Med Sci. 2006 Jun;68(6):537-41.
10. The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. Kojro E, etal., FASEB J. 2006 Mar;20(3):512-4. Epub 2006 Jan 9.
11. High-resolution fractionation of signaling endosomes containing different receptors. McCaffrey G, etal., Traffic. 2009 Jul;10(7):938-50. Epub 2009 Mar 5.
12. ADP-ribosylation factor-dependent phospholipase D activation by VPAC receptors and a PAC(1) receptor splice variant. McCulloch DA, etal., Mol Pharmacol. 2001 Jun;59(6):1523-32.
13. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
14. Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons. Miampamba M, etal., Regul Pept 2002 May 30;105(3):145-54.
15. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
16. Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation. Nicot A, etal., J Neurosci 2002 Nov 1;22(21):9244-54.
17. PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells. Oh DS, etal., J Mol Neurosci. 2005;26(1):85-97.
18. VIP provides cellular protection through a specific splice variant of the PACAP receptor: a new neuroprotection target. Pilzer I and Gozes I, Peptides. 2006 Nov;27(11):2867-76. Epub 2006 Aug 14.
19. Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor. Pisegna JR and Wank SA, Proc Natl Acad Sci U S A 1993 Jul 1;90(13):6345-9.
20. Involvement of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors in the mechanism of antidepressant action. Reichenstein M, etal., J Mol Neurosci. 2008 Nov;36(1-3):330-8. Epub 2008 Jul 1.
21. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Differential regulation of CXCL12 and PACAP mRNA expression after focal and global ischemia. Riek-Burchardt M, etal., Neuropharmacology. 2010 Jan;58(1):199-207. Epub 2009 Jul 30.
24. Distribution and ultrastructural localization of a receptor for pituitary adenylate cyclase activating polypeptide and its mRNA in the rat retina. Seki T, etal., Neurosci Lett. 1997 Dec 5;238(3):127-30.
25. Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation. Shi GX, etal., Mol Cell Biol. 2008 Aug;28(16):4940-51. Epub 2008 Jun 9.
26. Differential signal transduction by five splice variants of the PACAP receptor. Spengler D, etal., Nature 1993 Sep 9;365(6442):170-5.
27. Implication of pituitary adenylate cyclase-activating polypeptide (PACAP) for neuroprotection of nicotinic acetylcholine receptor signaling in PC12 cells. Tominaga A, etal., J Mol Neurosci. 2008 Nov;36(1-3):73-8. Epub 2008 Jul 15.
28. Characterization and expression of different pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptors in rat ovarian follicles. Vaccari S, etal., J Endocrinol. 2006 Oct;191(1):287-99.
29. Pituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells. Zhang W, etal., J Neurochem. 2007 Nov;103(3):1157-67. Epub 2007 Aug 6.
Additional References at PubMed
PMID:7687425   PMID:8394723   PMID:8394834   PMID:8396930   PMID:9115282   PMID:11784714   PMID:15344914   PMID:16888209   PMID:16888214   PMID:16888229   PMID:17213203   PMID:18337184  
PMID:18353507   PMID:20093365   PMID:20599818   PMID:21539889   PMID:21620115   PMID:21693142   PMID:22715380   PMID:22766684   PMID:22886412   PMID:23080176   PMID:23382219   PMID:23690336  
PMID:23801193   PMID:24352804   PMID:24508136   PMID:27181029   PMID:32142016   PMID:32186931   PMID:35001657   PMID:35460713   PMID:36430275   PMID:37511603  


Genomics

Comparative Map Data
Adcyap1r1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,924,171 - 85,972,973 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl485,924,100 - 85,972,973 (+)EnsemblGRCr8
mRatBN7.2484,593,558 - 84,642,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx489,816,241 - 89,865,223 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0485,591,645 - 85,640,627 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,997,328 - 84,046,283 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,662,809 - 85,711,696 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensemblrn6Rnor6.0
Rnor_5.04150,314,846 - 150,363,650 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4484,209,729 - 84,254,982 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera479,461,538 - 79,510,340 (+)NCBICelera
RGSC_v3.1484,478,820 - 84,501,994 (+)NCBI
Cytogenetic Map4q24NCBI
ADCYAP1R1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38731,052,308 - 31,111,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl731,052,308 - 31,111,475 (+)Ensemblhg38GRCh38
GRCh37731,091,923 - 31,151,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36731,058,667 - 31,112,836 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34730,865,381 - 30,919,551NCBI
Celera731,081,020 - 31,135,194 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,974,048 - 31,033,016 (+)NCBIHuRef
CHM1_1731,091,676 - 31,150,684 (+)NCBICHM1_1
T2T-CHM13v2.0731,189,955 - 31,249,113 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2731,141,254 - 31,200,271 (+)NCBI
Adcyap1r1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39655,428,486 - 55,478,440 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl655,428,963 - 55,478,436 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38655,451,501 - 55,501,455 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl655,451,978 - 55,501,451 (+)Ensemblmm10GRCm38
MGSCv37655,401,974 - 55,451,449 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36655,381,558 - 55,431,033 (+)NCBIMGSCv36mm8
Celera655,983,712 - 56,033,208 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
Adcyap1r1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,176,536 - 32,229,431 (+)Ensembl
ChiLan1.0NW_00495541032,176,683 - 32,229,187 (+)NCBIChiLan1.0ChiLan1.0
ADCYAP1R1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2635,795,205 - 35,922,226 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1784,119,933 - 84,246,953 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0731,597,251 - 31,724,299 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1731,716,396 - 31,843,381 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl731,784,622 - 31,843,381 (+)EnsemblpanPan2panpan1.1
ADCYAP1R1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11443,707,683 - 43,761,166 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1443,701,745 - 43,756,571 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1443,134,310 - 43,193,229 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01443,642,714 - 43,701,564 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1443,643,278 - 43,701,558 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11443,776,867 - 43,827,123 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01443,435,411 - 43,493,816 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01443,796,177 - 43,855,281 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adcyap1r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511888,066,317 - 88,111,238 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364787,278,147 - 7,318,458 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364787,278,081 - 7,322,970 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCYAP1R1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1841,917,428 - 41,972,301 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11841,915,180 - 41,972,327 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ADCYAP1R1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12127,274,039 - 27,333,316 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2127,278,788 - 27,333,220 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604277,371,163 - 77,431,527 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcyap1r1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624783279,745 - 323,772 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624783271,179 - 323,785 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Adcyap1r1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1685,550,567 - 85,623,751 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adcyap1r1
336 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1069
Count of miRNA genes:194
Interacting mature miRNAs:227
Transcripts:ENSRNOT00000016175, ENSRNOT00000035722, ENSRNOT00000043851, ENSRNOT00000046192
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)480216705104243248Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48279077797183061Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat

Markers in Region
AI846590  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2484,642,503 - 84,642,624 (+)MAPPERmRatBN7.2
Rnor_6.0485,711,500 - 85,711,620NCBIRnor6.0
Rnor_5.04150,363,454 - 150,363,574UniSTSRnor5.0
RGSC_v3.4484,258,337 - 84,258,457UniSTSRGSC3.4
Celera479,510,144 - 79,510,264UniSTS
Cytogenetic Map4q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 162 91 90 59 30 59 6 286 130 11 138 74 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR475040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L16506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L16680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U82669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U84740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U84741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U84742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U84743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016175   ⟹   ENSRNOP00000016175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,924,171 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)Ensembl
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000035722   ⟹   ENSRNOP00000030759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,924,100 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)Ensembl
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000043851   ⟹   ENSRNOP00000044267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,924,171 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)Ensembl
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000046192   ⟹   ENSRNOP00000050048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,924,171 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)Ensembl
Rnor_6.0 Ensembl485,662,892 - 85,711,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103561   ⟹   ENSRNOP00000082399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,933,147 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,602,868 - 84,642,700 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112901   ⟹   ENSRNOP00000090556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl485,924,171 - 85,972,973 (+)Ensembl
mRatBN7.2 Ensembl484,593,892 - 84,642,700 (+)Ensembl
RefSeq Acc Id: NM_001270579   ⟹   NP_001257508
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270580   ⟹   NP_001257509
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270581   ⟹   NP_001257510
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270582   ⟹   NP_001257511
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270583   ⟹   NP_001257512
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: NM_133511   ⟹   NP_598195
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,171 - 85,972,973 (+)NCBI
mRatBN7.2484,593,892 - 84,642,700 (+)NCBI
Rnor_6.0485,662,892 - 85,711,696 (+)NCBI
Rnor_5.04150,314,846 - 150,363,650 (+)NCBI
RGSC_v3.4484,209,729 - 84,254,982 (+)RGD
Celera479,461,538 - 79,510,340 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039106996   ⟹   XP_038962924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
mRatBN7.2484,593,817 - 84,642,700 (+)NCBI
RefSeq Acc Id: XM_039106999   ⟹   XP_038962927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
mRatBN7.2484,593,816 - 84,642,700 (+)NCBI
RefSeq Acc Id: XM_039107000   ⟹   XP_038962928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
mRatBN7.2484,593,823 - 84,642,700 (+)NCBI
RefSeq Acc Id: XM_063285463   ⟹   XP_063141533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285464   ⟹   XP_063141534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,293 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285465   ⟹   XP_063141535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,293 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285466   ⟹   XP_063141536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285467   ⟹   XP_063141537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,292 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285468   ⟹   XP_063141538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,293 - 85,972,973 (+)NCBI
RefSeq Acc Id: XM_063285469   ⟹   XP_063141539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,924,293 - 85,972,973 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001257508 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257509 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257510 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257511 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257512 (Get FASTA)   NCBI Sequence Viewer  
  NP_598195 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962924 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962927 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962928 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141533 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141534 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141535 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141536 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141537 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141538 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141539 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA02990 (Get FASTA)   NCBI Sequence Viewer  
  AAA41792 (Get FASTA)   NCBI Sequence Viewer  
  AAG16771 (Get FASTA)   NCBI Sequence Viewer  
  BAA03608 (Get FASTA)   NCBI Sequence Viewer  
  BAA03609 (Get FASTA)   NCBI Sequence Viewer  
  BAA03932 (Get FASTA)   NCBI Sequence Viewer  
  CAA80429 (Get FASTA)   NCBI Sequence Viewer  
  CAA80810 (Get FASTA)   NCBI Sequence Viewer  
  CAA80811 (Get FASTA)   NCBI Sequence Viewer  
  CAA80812 (Get FASTA)   NCBI Sequence Viewer  
  CAA80813 (Get FASTA)   NCBI Sequence Viewer  
  CAA80817 (Get FASTA)   NCBI Sequence Viewer  
  CAA80820 (Get FASTA)   NCBI Sequence Viewer  
  CAA80821 (Get FASTA)   NCBI Sequence Viewer  
  EDL88073 (Get FASTA)   NCBI Sequence Viewer  
  EDL88074 (Get FASTA)   NCBI Sequence Viewer  
  EDL88075 (Get FASTA)   NCBI Sequence Viewer  
  EDL88076 (Get FASTA)   NCBI Sequence Viewer  
  EDL88077 (Get FASTA)   NCBI Sequence Viewer  
  EDL88078 (Get FASTA)   NCBI Sequence Viewer  
  EDL88079 (Get FASTA)   NCBI Sequence Viewer  
  EDL88080 (Get FASTA)   NCBI Sequence Viewer  
  EDL88081 (Get FASTA)   NCBI Sequence Viewer  
  EDL88082 (Get FASTA)   NCBI Sequence Viewer  
  EDL88083 (Get FASTA)   NCBI Sequence Viewer  
  EDL88084 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016175
  ENSRNOP00000016175.3
  ENSRNOP00000030759
  ENSRNOP00000030759.2
  ENSRNOP00000044267
  ENSRNOP00000044267.2
  ENSRNOP00000050048
  ENSRNOP00000050048.2
  ENSRNOP00000082399
GenBank Protein P32215 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_598195   ⟸   NM_133511
- Peptide Label: isoform b precursor
- UniProtKB: A6K0Z2 (UniProtKB/TrEMBL),   A0A8I6GIB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257510   ⟸   NM_001270581
- Peptide Label: isoform d precursor
- UniProtKB: A6K0Z5 (UniProtKB/TrEMBL),   A0A8I6GIB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257508   ⟸   NM_001270579
- Peptide Label: isoform a precursor
- UniProtKB: Q63414 (UniProtKB/Swiss-Prot),   P32215 (UniProtKB/Swiss-Prot),   A6K0Y6 (UniProtKB/TrEMBL),   A0A8I5ZUV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257509   ⟸   NM_001270580
- Peptide Label: isoform c precursor
- UniProtKB: A6K0Y9 (UniProtKB/TrEMBL),   A0A8I6GIB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257512   ⟸   NM_001270583
- Peptide Label: isoform e precursor
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257511   ⟸   NM_001270582
- Peptide Label: isoform d precursor
- UniProtKB: A6K0Z5 (UniProtKB/TrEMBL),   A0A8I6GIB0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016175   ⟸   ENSRNOT00000016175
Ensembl Acc Id: ENSRNOP00000044267   ⟸   ENSRNOT00000043851
Ensembl Acc Id: ENSRNOP00000030759   ⟸   ENSRNOT00000035722
Ensembl Acc Id: ENSRNOP00000050048   ⟸   ENSRNOT00000046192
RefSeq Acc Id: XP_038962927   ⟸   XM_039106999
- Peptide Label: isoform X4
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962924   ⟸   XM_039106996
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962928   ⟸   XM_039107000
- Peptide Label: isoform X7
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090556   ⟸   ENSRNOT00000112901
Ensembl Acc Id: ENSRNOP00000082399   ⟸   ENSRNOT00000103561
RefSeq Acc Id: XP_063141533   ⟸   XM_063285463
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141536   ⟸   XM_063285466
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141537   ⟸   XM_063285467
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZUV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141534   ⟸   XM_063285464
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141535   ⟸   XM_063285465
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141538   ⟸   XM_063285468
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL),   A6K0Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141539   ⟸   XM_063285469
- Peptide Label: isoform X8
- UniProtKB: A0A8I6GIB0 (UniProtKB/TrEMBL),   A6K0Z5 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P32215-F1-model_v2 AlphaFold P32215 1-523 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693075
Promoter ID:EPDNEW_R3599
Type:single initiation site
Name:Adcyap1r1_1
Description:ADCYAP receptor type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0485,662,821 - 85,662,881EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2038 AgrOrtholog
BioCyc Gene G2FUF-44729 BioCyc
Ensembl Genes ENSRNOG00000012098 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016175 ENTREZGENE
  ENSRNOT00000016175.6 UniProtKB/Swiss-Prot
  ENSRNOT00000035722 ENTREZGENE
  ENSRNOT00000035722.5 UniProtKB/Swiss-Prot
  ENSRNOT00000043851 ENTREZGENE
  ENSRNOT00000043851.4 UniProtKB/Swiss-Prot
  ENSRNOT00000046192 ENTREZGENE
  ENSRNOT00000046192.5 UniProtKB/Swiss-Prot
  ENSRNOT00000103561 ENTREZGENE
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_2 UniProtKB/Swiss-Prot
  GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot
  GPCR_2_PACAP_1_rcpt UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot
KEGG Report rno:24167 UniProtKB/Swiss-Prot
NCBI Gene 24167 ENTREZGENE
PANTHER PDF RECEPTOR-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot
  PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_2 UniProtKB/Swiss-Prot
  HRM UniProtKB/Swiss-Prot
PhenoGen Adcyap1r1 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot
  PACAPRECEPTR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012098 RatGTEx
SMART HormR UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
  SSF111418 UniProtKB/Swiss-Prot
UniProt A0A8I5ZUV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIB0 ENTREZGENE, UniProtKB/TrEMBL
  A6K0Y6 ENTREZGENE, UniProtKB/TrEMBL
  A6K0Y9 ENTREZGENE, UniProtKB/TrEMBL
  A6K0Z2 ENTREZGENE, UniProtKB/TrEMBL
  A6K0Z5 ENTREZGENE, UniProtKB/TrEMBL
  P32215 ENTREZGENE, UniProtKB/Swiss-Prot
  Q63414 ENTREZGENE
UniProt Secondary Q63414 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-25 Adcyap1r1  ADCYAP receptor type I  Adcyap1r1  ADCYAP receptor type 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-03-02 Adcyap1r1  ADCYAP receptor type 1  Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor type 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-02-25 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor type 1  Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-28 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1  Adcyap1r1  adenylate cyclase activating polypeptide 1 (pituitary) receptor type I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Adcyap1r1  adenylate cyclase activating polypeptide 1 (pituitary) receptor type I  Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1  Adcyap1r-1  adenylate cyclase activating polypeptide 1 type 1 receptor  Symbol and Name updated 1299863 APPROVED
2001-06-29 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED
2001-06-29 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1      Name withdrawn 67952 WITHDRAWN
2001-06-18 Adcyap1r1  adenylate cyclase activating polypeptide 1 receptor 1      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED
2001-06-18 Adcyap1r1  Rat pituitary adenylate cyclase activating polypeptide 1 receptor (1)      Name withdrawn 67952 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_disease a therapeutic target in childhood medulloblastoma (a granule cell malignancy caused by abnormal Shh-signaling) 628387
gene_domains contains seven transmembrane domains characteristic of G-protein coupled receptors 631731
gene_expression expressed in the hypothalamus, brain stem, adrenal gland, testis, and pituitary 631732
gene_expression mRNA expressed in the developing cerebellum 628387
gene_function high-affinity receptor for pituitary adenylyl cyclase-activating polypeptide 631731
gene_process involved in adenylyl cyclase and phospholipase C mediated signaling 631732
gene_process regulates neuropeptide signaling 631731
gene_process regulates neural precursor proliferation 628387
gene_process participates in inhibitory signaling for Shh-induced proliferation in the developing cerebellum 628387
gene_transcript has four splice variants with insertions within the third intracellular loop 631732