Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Adcyap1r1 | Rat | asthma | | ISO | ADCYAP1R1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21059121 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Adcyap1r1 | Rat | asthma | | ISO | ADCYAP1R1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21059121 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) in the cochlea: evidence for specific transcript expression of PAC1-R splice variants in rat microdissected cochlear subfractions. | Abu-Hamdan MD, etal., Neuroscience. 2006 Jun 19;140(1):147-61. Epub 2006 Apr 19. |
| 2. | PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. | Apostolakis EM, etal., Mol Endocrinol. 2005 Nov;19(11):2798-811. Epub 2005 Jun 23. |
| 3. | Molecular cloning of a novel variant of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor that stimulates calcium influx by activation of L-type calcium channels. | Chatterjee TK, etal., J Biol Chem. 1996 Dec 13;271(50):32226-32. |
| 4. | Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea. | Drescher MJ, etal., Neuroscience. 2006 Sep 29;142(1):139-64. Epub 2006 Jul 31. |
| 5. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 6. | PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis. | Girard BM, etal., J Mol Neurosci. 2008 Nov;36(1-3):310-20. Epub 2008 Jun 19. |
| 7. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 8. | Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior. | Hammack SE, etal., Psychoneuroendocrinology. 2009 Jul;34(6):833-43. Epub 2009 Jan 31. |
| 9. | Decrease of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in rat testes by ethanol exposure. | Koh PO and Won CK, J Vet Med Sci. 2006 Jun;68(6):537-41. |
| 10. | The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. | Kojro E, etal., FASEB J. 2006 Mar;20(3):512-4. Epub 2006 Jan 9. |
| 11. | High-resolution fractionation of signaling endosomes containing different receptors. | McCaffrey G, etal., Traffic. 2009 Jul;10(7):938-50. Epub 2009 Mar 5. |
| 12. | ADP-ribosylation factor-dependent phospholipase D activation by VPAC receptors and a PAC(1) receptor splice variant. | McCulloch DA, etal., Mol Pharmacol. 2001 Jun;59(6):1523-32. |
| 13. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 14. | Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons. | Miampamba M, etal., Regul Pept 2002 May 30;105(3):145-54. |
| 15. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 16. | Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation. | Nicot A, etal., J Neurosci 2002 Nov 1;22(21):9244-54. |
| 17. | PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells. | Oh DS, etal., J Mol Neurosci. 2005;26(1):85-97. |
| 18. | VIP provides cellular protection through a specific splice variant of the PACAP receptor: a new neuroprotection target. | Pilzer I and Gozes I, Peptides. 2006 Nov;27(11):2867-76. Epub 2006 Aug 14. |
| 19. | Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor. | Pisegna JR and Wank SA, Proc Natl Acad Sci U S A 1993 Jul 1;90(13):6345-9. |
| 20. | Involvement of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors in the mechanism of antidepressant action. | Reichenstein M, etal., J Mol Neurosci. 2008 Nov;36(1-3):330-8. Epub 2008 Jul 1. |
| 21. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 22. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 23. | Differential regulation of CXCL12 and PACAP mRNA expression after focal and global ischemia. | Riek-Burchardt M, etal., Neuropharmacology. 2010 Jan;58(1):199-207. Epub 2009 Jul 30. |
| 24. | Distribution and ultrastructural localization of a receptor for pituitary adenylate cyclase activating polypeptide and its mRNA in the rat retina. | Seki T, etal., Neurosci Lett. 1997 Dec 5;238(3):127-30. |
| 25. | Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation. | Shi GX, etal., Mol Cell Biol. 2008 Aug;28(16):4940-51. Epub 2008 Jun 9. |
| 26. | Differential signal transduction by five splice variants of the PACAP receptor. | Spengler D, etal., Nature 1993 Sep 9;365(6442):170-5. |
| 27. | Implication of pituitary adenylate cyclase-activating polypeptide (PACAP) for neuroprotection of nicotinic acetylcholine receptor signaling in PC12 cells. | Tominaga A, etal., J Mol Neurosci. 2008 Nov;36(1-3):73-8. Epub 2008 Jul 15. |
| 28. | Characterization and expression of different pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptors in rat ovarian follicles. | Vaccari S, etal., J Endocrinol. 2006 Oct;191(1):287-99. |
| 29. | Pituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells. | Zhang W, etal., J Neurochem. 2007 Nov;103(3):1157-67. Epub 2007 Aug 6. |
| PMID:7687425 | PMID:8394723 | PMID:8394834 | PMID:8396930 | PMID:9115282 | PMID:11784714 | PMID:15344914 | PMID:16888209 | PMID:16888214 | PMID:16888229 | PMID:17213203 | PMID:18337184 |
| PMID:18353507 | PMID:20093365 | PMID:20599818 | PMID:21539889 | PMID:21620115 | PMID:21693142 | PMID:22715380 | PMID:22766684 | PMID:22886412 | PMID:23080176 | PMID:23382219 | PMID:23690336 |
| PMID:23801193 | PMID:24352804 | PMID:24508136 | PMID:27181029 | PMID:32142016 | PMID:32186931 | PMID:35001657 | PMID:35460713 | PMID:36430275 | PMID:37511603 |
| Adcyap1r1 (Rattus norvegicus - Norway rat) |
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| ADCYAP1R1 (Homo sapiens - human) |
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| Adcyap1r1 (Mus musculus - house mouse) |
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| Adcyap1r1 (Chinchilla lanigera - long-tailed chinchilla) |
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| ADCYAP1R1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ADCYAP1R1 (Canis lupus familiaris - dog) |
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| Adcyap1r1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ADCYAP1R1 (Sus scrofa - pig) |
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| ADCYAP1R1 (Chlorocebus sabaeus - green monkey) |
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| Adcyap1r1 (Heterocephalus glaber - naked mole-rat) |
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| Adcyap1r1 (Rattus rattus - black rat) |
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Variants in Adcyap1r1
336 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| AI846590 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 15 | 12 | 67 | 162 | 91 | 90 | 59 | 30 | 59 | 6 | 286 | 130 | 11 | 138 | 74 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001270579 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_001270580 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001270581 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001270582 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001270583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_133511 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017592429 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017592430 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017592431 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039106996 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039106999 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039107000 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285463 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285464 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285465 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285466 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285467 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285468 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063285469 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AC091657 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| CH474011 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CR475040 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| D14908 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| D14909 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| D16465 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000004 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| L16506 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| L16680 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U82669 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U84740 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U84741 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U84742 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U84743 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z22735 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23272 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23273 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23274 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23275 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23279 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| Z23282 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000016175 ⟹ ENSRNOP00000016175 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000035722 ⟹ ENSRNOP00000030759 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000043851 ⟹ ENSRNOP00000044267 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000046192 ⟹ ENSRNOP00000050048 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000103561 ⟹ ENSRNOP00000082399 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000112901 ⟹ ENSRNOP00000090556 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001270579 ⟹ NP_001257508 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_001270580 ⟹ NP_001257509 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_001270581 ⟹ NP_001257510 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_001270582 ⟹ NP_001257511 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_001270583 ⟹ NP_001257512 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_133511 ⟹ NP_598195 | ||||||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039106996 ⟹ XP_038962924 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039106999 ⟹ XP_038962927 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039107000 ⟹ XP_038962928 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285463 ⟹ XP_063141533 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285464 ⟹ XP_063141534 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285465 ⟹ XP_063141535 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285466 ⟹ XP_063141536 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285467 ⟹ XP_063141537 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285468 ⟹ XP_063141538 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063285469 ⟹ XP_063141539 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001257508 | (Get FASTA) | NCBI Sequence Viewer |
| NP_001257509 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001257510 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001257511 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001257512 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_598195 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038962924 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038962927 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038962928 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141533 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141534 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141535 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141536 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141537 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141538 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063141539 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAA02990 | (Get FASTA) | NCBI Sequence Viewer |
| AAA41792 | (Get FASTA) | NCBI Sequence Viewer | |
| AAG16771 | (Get FASTA) | NCBI Sequence Viewer | |
| BAA03608 | (Get FASTA) | NCBI Sequence Viewer | |
| BAA03609 | (Get FASTA) | NCBI Sequence Viewer | |
| BAA03932 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80429 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80810 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80811 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80812 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80813 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80817 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80820 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA80821 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88073 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88074 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88075 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88076 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88077 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88078 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88079 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88080 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88081 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88082 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88083 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL88084 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000016175 | ||
| ENSRNOP00000016175.3 | |||
| ENSRNOP00000030759 | |||
| ENSRNOP00000030759.2 | |||
| ENSRNOP00000044267 | |||
| ENSRNOP00000044267.2 | |||
| ENSRNOP00000050048 | |||
| ENSRNOP00000050048.2 | |||
| ENSRNOP00000082399 | |||
| GenBank Protein | P32215 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_598195 ⟸ NM_133511 |
| - Peptide Label: | isoform b precursor |
| - UniProtKB: | A6K0Z2 (UniProtKB/TrEMBL), A0A8I6GIB0 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001257510 ⟸ NM_001270581 |
| - Peptide Label: | isoform d precursor |
| - UniProtKB: | A6K0Z5 (UniProtKB/TrEMBL), A0A8I6GIB0 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001257508 ⟸ NM_001270579 |
| - Peptide Label: | isoform a precursor |
| - UniProtKB: | Q63414 (UniProtKB/Swiss-Prot), P32215 (UniProtKB/Swiss-Prot), A6K0Y6 (UniProtKB/TrEMBL), A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001257509 ⟸ NM_001270580 |
| - Peptide Label: | isoform c precursor |
| - UniProtKB: | A6K0Y9 (UniProtKB/TrEMBL), A0A8I6GIB0 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001257512 ⟸ NM_001270583 |
| - Peptide Label: | isoform e precursor |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001257511 ⟸ NM_001270582 |
| - Peptide Label: | isoform d precursor |
| - UniProtKB: | A6K0Z5 (UniProtKB/TrEMBL), A0A8I6GIB0 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000016175 ⟸ ENSRNOT00000016175 |
| Ensembl Acc Id: | ENSRNOP00000044267 ⟸ ENSRNOT00000043851 |
| Ensembl Acc Id: | ENSRNOP00000030759 ⟸ ENSRNOT00000035722 |
| Ensembl Acc Id: | ENSRNOP00000050048 ⟸ ENSRNOT00000046192 |
| RefSeq Acc Id: | XP_038962927 ⟸ XM_039106999 |
| - Peptide Label: | isoform X4 |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038962924 ⟸ XM_039106996 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038962928 ⟸ XM_039107000 |
| - Peptide Label: | isoform X7 |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000090556 ⟸ ENSRNOT00000112901 |
| Ensembl Acc Id: | ENSRNOP00000082399 ⟸ ENSRNOT00000103561 |
| RefSeq Acc Id: | XP_063141533 ⟸ XM_063285463 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141536 ⟸ XM_063285466 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141537 ⟸ XM_063285467 |
| - Peptide Label: | isoform X5 |
| - UniProtKB: | A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141534 ⟸ XM_063285464 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141535 ⟸ XM_063285465 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A8I5ZUV4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141538 ⟸ XM_063285468 |
| - Peptide Label: | isoform X6 |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL), A6K0Z2 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063141539 ⟸ XM_063285469 |
| - Peptide Label: | isoform X8 |
| - UniProtKB: | A0A8I6GIB0 (UniProtKB/TrEMBL), A6K0Z5 (UniProtKB/TrEMBL) |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-P32215-F1-model_v2 | AlphaFold | P32215 | 1-523 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13693075 | ||||||||
| Promoter ID: | EPDNEW_R3599 | ||||||||
| Type: | single initiation site | ||||||||
| Name: | Adcyap1r1_1 | ||||||||
| Description: | ADCYAP receptor type 1 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
|
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:2038 | AgrOrtholog |
| BioCyc Gene | G2FUF-44729 | BioCyc |
| Ensembl Genes | ENSRNOG00000012098 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000016175 | ENTREZGENE |
| ENSRNOT00000016175.6 | UniProtKB/Swiss-Prot | |
| ENSRNOT00000035722 | ENTREZGENE | |
| ENSRNOT00000035722.5 | UniProtKB/Swiss-Prot | |
| ENSRNOT00000043851 | ENTREZGENE | |
| ENSRNOT00000043851.4 | UniProtKB/Swiss-Prot | |
| ENSRNOT00000046192 | ENTREZGENE | |
| ENSRNOT00000046192.5 | UniProtKB/Swiss-Prot | |
| ENSRNOT00000103561 | ENTREZGENE | |
| Gene3D-CATH | 4.10.1240.10 | UniProtKB/Swiss-Prot |
| Rhodopsin 7-helix transmembrane proteins | UniProtKB/Swiss-Prot | |
| InterPro | GPCR_2 | UniProtKB/Swiss-Prot |
| GPCR_2-like | UniProtKB/Swiss-Prot | |
| GPCR_2_extracell_dom_sf | UniProtKB/Swiss-Prot | |
| GPCR_2_extracellular_dom | UniProtKB/Swiss-Prot | |
| GPCR_2_PACAP_1_rcpt | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like_CS | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:24167 | UniProtKB/Swiss-Prot |
| NCBI Gene | 24167 | ENTREZGENE |
| PANTHER | PDF RECEPTOR-LIKE PROTEIN-RELATED | UniProtKB/Swiss-Prot |
| PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR | UniProtKB/Swiss-Prot | |
| Pfam | 7tm_2 | UniProtKB/Swiss-Prot |
| HRM | UniProtKB/Swiss-Prot | |
| PhenoGen | Adcyap1r1 | PhenoGen |
| PRINTS | GPCRSECRETIN | UniProtKB/Swiss-Prot |
| PACAPRECEPTR | UniProtKB/Swiss-Prot | |
| PROSITE | G_PROTEIN_RECEP_F2_1 | UniProtKB/Swiss-Prot |
| G_PROTEIN_RECEP_F2_2 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_3 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_4 | UniProtKB/Swiss-Prot | |
| RatGTEx | ENSRNOG00000012098 | RatGTEx |
| SMART | HormR | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | Family A G protein-coupled receptor-like | UniProtKB/Swiss-Prot |
| SSF111418 | UniProtKB/Swiss-Prot | |
| UniProt | A0A8I5ZUV4 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A8I6GIB0 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6K0Y6 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6K0Y9 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6K0Z2 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6K0Z5 | ENTREZGENE, UniProtKB/TrEMBL | |
| P32215 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| Q63414 | ENTREZGENE | |
| UniProt Secondary | Q63414 | UniProtKB/Swiss-Prot |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2019-03-25 | Adcyap1r1 | ADCYAP receptor type I | Adcyap1r1 | ADCYAP receptor type 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2017-03-02 | Adcyap1r1 | ADCYAP receptor type 1 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor type 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2015-02-25 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor type 1 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2010-05-28 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-09-18 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-05-15 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Adcyap1r-1 | adenylate cyclase activating polypeptide 1 type 1 receptor | Symbol and Name updated | 1299863 | APPROVED |
| 2001-06-29 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Name updated to reflect Human and Mouse nomenclature | 67952 | APPROVED | ||
| 2001-06-29 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Name withdrawn | 67952 | WITHDRAWN | ||
| 2001-06-18 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Name updated to reflect Human and Mouse nomenclature | 67952 | APPROVED | ||
| 2001-06-18 | Adcyap1r1 | Rat pituitary adenylate cyclase activating polypeptide 1 receptor (1) | Name withdrawn | 67952 | WITHDRAWN |
| Note Type | Note | Reference |
|---|---|---|
| gene_disease | a therapeutic target in childhood medulloblastoma (a granule cell malignancy caused by abnormal Shh-signaling) | 628387 |
| gene_domains | contains seven transmembrane domains characteristic of G-protein coupled receptors | 631731 |
| gene_expression | expressed in the hypothalamus, brain stem, adrenal gland, testis, and pituitary | 631732 |
| gene_expression | mRNA expressed in the developing cerebellum | 628387 |
| gene_function | high-affinity receptor for pituitary adenylyl cyclase-activating polypeptide | 631731 |
| gene_process | involved in adenylyl cyclase and phospholipase C mediated signaling | 631732 |
| gene_process | regulates neuropeptide signaling | 631731 |
| gene_process | regulates neural precursor proliferation | 628387 |
| gene_process | participates in inhibitory signaling for Shh-induced proliferation in the developing cerebellum | 628387 |
| gene_transcript | has four splice variants with insertions within the third intracellular loop | 631732 |