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Gene: Ano2 (anoctamin 2) Rattus norvegicus

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Symbol:

Ano2

Name:

anoctamin 2

RGD ID:

1591606

Description:

Enables intracellularly calcium-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to act upstream of or within chloride transport and establishment of localization in cell. Predicted to be located in neuron projection and non-motile cilium. Predicted to be active in glutamatergic synapse and presynaptic membrane. Orthologous to human ANO2 (anoctamin 2); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

anoctamin 2, calcium activated chloride channel; anoctamin 2-like; anoctamin-2; anoctamin-2-like; LOC100361584; LOC100912468; LOC683001; similar to Transmembrane protein 16B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANO2 (anoctamin 2)	RGD	RGD
Mus musculus (house mouse):	Ano2 (anoctamin 2)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Ano2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANO2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANO2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ano2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANO2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANO2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ano2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ano2 (anoctamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ANO1 (anoctamin 1)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ANO2 (anoctamin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ano2 (anoctamin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ano2b (anoctamin 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ano2b (anoctamin 2b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	anoh-1	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	subdued	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	subdued	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ano2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ano2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	ano2a	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	160,200,471 - 160,541,830 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	160,182,152 - 160,541,821 (+)	Ensembl				GRCr8
mRatBN7.2	4	158,514,200 - 158,855,639 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	158,496,014 - 158,855,651 (+)	Ensembl				mRatBN7.2
Rnor_6.0	4	158,222,650 - 158,577,595 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	158,224,000 - 158,576,978 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	225,312,041 - 225,579,493 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	162,315,059 - 162,376,029 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	147,226,836 - 147,581,598 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (EXP)

doxorubicin (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

glyphosate (EXP,ISO)

L-methionine (ISO)

lead diacetate (ISO)

lead(0) (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methoxychlor (EXP)

nickel sulfate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transmembrane transport (IBA)

chloride transport (ISO)

Cellular Component

glutamatergic synapse (IEA,ISO)

membrane (IEA)

non-motile cilium (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

presynaptic membrane (IEA,ISO)

Molecular Function

identical protein binding (IEA,ISO)

intracellularly calcium-gated chloride channel activity (IBA,IDA,IEA,IMP,ISO)

protein binding (ISO)

protein dimerization activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels.	Vocke K, etal., J Gen Physiol. 2013 Oct;142(4):381-404. doi: 10.1085/jgp.201311015.

Additional References at PubMed

PMID:15632090	PMID:19474308	PMID:19475416	PMID:19561302	PMID:20056604	PMID:21516098	PMID:21984732	PMID:22075693	PMID:22314846	PMID:23532839	PMID:23557741	PMID:23576756
PMID:29187602

Genomics

Comparative Map Data

Ano2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	160,200,471 - 160,541,830 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	160,182,152 - 160,541,821 (+)	Ensembl				GRCr8
mRatBN7.2	4	158,514,200 - 158,855,639 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	158,496,014 - 158,855,651 (+)	Ensembl				mRatBN7.2
Rnor_6.0	4	158,222,650 - 158,577,595 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	158,224,000 - 158,576,978 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	225,312,041 - 225,579,493 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	162,315,059 - 162,376,029 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	147,226,836 - 147,581,598 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

ANO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	5,562,655 - 5,946,232 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	5,531,869 - 5,946,232 (-)	Ensembl			hg38	GRCh38
GRCh37	12	5,671,821 - 6,055,398 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	5,542,081 - 5,925,659 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	5,542,080 - 5,925,659	NCBI
Celera	12	7,292,577 - 7,675,047 (-)	NCBI		Celera
Cytogenetic Map	12	p13.31	NCBI
HuRef	12	5,525,403 - 5,907,364 (-)	NCBI		HuRef
CHM1_1	12	5,671,608 - 6,054,794 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	5,569,523 - 5,953,779 (-)	NCBI		T2T-CHM13v2.0

Ano2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	125,667,382 - 126,017,115 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	125,667,382 - 126,017,089 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	125,690,419 - 126,040,133 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	125,690,419 - 126,040,126 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	125,640,437 - 125,990,151 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	125,676,322 - 126,005,752 (+)	NCBI		MGSCv36	mm8
MGSCv36	6	126,602,651 - 126,934,718 (+)	NCBI		MGSCv36	mm8
Celera	6	127,350,653 - 127,704,257 (+)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI
cM Map	6	59.58	NCBI

Ano2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	3,333,289 - 3,668,587 (-)	Ensembl
ChiLan1.0	NW_004955413	3,333,275 - 3,650,255 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	11,117,549 - 11,501,548 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	11,114,307 - 11,498,306 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	5,690,023 - 6,071,283 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	5,608,895 - 5,987,004 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	5,609,541 - 5,987,900 (-)	Ensembl			panPan2	panpan1.1

ANO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	38,976,761 - 39,320,764 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	38,833,837 - 39,320,142 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	7,295,718 - 7,637,739 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	39,333,634 - 39,677,324 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	39,332,399 - 39,697,998 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	39,204,162 - 39,546,469 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	39,246,081 - 39,587,939 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	6,773,567 - 7,115,529 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ano2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	103,078,168 - 103,430,124 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936709	1,745,804 - 2,096,989 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936709	1,771,763 - 2,097,668 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	64,660,442 - 65,002,453 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	64,660,047 - 65,002,453 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	67,262,230 - 67,279,876 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANO2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	5,610,509 - 5,970,580 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	5,611,162 - 5,969,478 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666063	2,246,131 - 2,623,038 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ano2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624860	2,531,904 - 2,854,862 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624860	2,531,196 - 2,835,248 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ano2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	21,860,700 - 22,193,246 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ano2
2113 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	40
Interacting mature miRNAs:	43
Transcripts:	ENSRNOT00000032112
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	146370897	184426481	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	134095016	179095016	Rat
1582237	Kidm34	Kidney mass QTL 34	4	0.0001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	4	149763204	169799698	Rat
6478757	Anxrr44	Anxiety related response QTL 44		0.01087	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	146370897	184426481	Rat
1358364	Sradr4	Stress Responsive Adrenal Weight QTL 4	4.92		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	131384565	176384565	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
61451	Ciaa4	CIA Autoantibody QTL 4	3.1		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	4	123870974	168870974	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	140059299	181024663	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	4	117559384	162559384	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	157292416	184426481	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	106848959	168870974	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94638356	168870820	Rat
7411558	Bw133	Body weight QTL 133	13.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	127263297	172263297	Rat
6478778	Anxrr51	Anxiety related response QTL 51		0.25384	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	126334185	171334185	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	147299608	184426481	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
6478782	Anxrr52	Anxiety related response QTL 52		0.02091	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
631511	Pia7	Pristane induced arthritis QTL 7	4.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
634347	Hcar8	Hepatocarcinoma resistance QTL 8	5.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	124700988	169700988	Rat
6478720	Alc23	Alcohol consumption QTL 23		0.00509	drinking behavior trait (VT:0001422)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	155834926	184426481	Rat
6478785	Anxrr53	Anxiety related response QTL 53		0.01397	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1581566	Eae21	Experimental allergic encephalomyelitis QTL 21	6.2		body mass (VT:0001259)	maximum body weight loss to initial body weight ratio (CMO:0001400)	4	137447185	182447185	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	137430611	182430611	Rat
6478728	Anxrr36	Anxiety related response QTL 36		0.01061	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86709649	168870974	Rat
61422	Cia13	Collagen induced arthritis QTL 13	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	134199006	168870974	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	148121375	176967367	Rat
6478733	Anxrr37	Anxiety related response QTL 37		0.00095	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
737978	Pia23	Pristane induced arthritis QTL 23	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
6478737	Anxrr38	Anxiety related response QTL 38		0.00159	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	116184844	161184844	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
12798525	Anxrr57	Anxiety related response QTL 57	3.21	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	148834094	168870974	Rat

Markers in Region

D4Got132

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	158,841,508 - 158,841,762 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	158,564,220 - 158,564,471	NCBI	Rnor6.0
Rnor_5.0	4	225,566,118 - 225,566,369	UniSTS	Rnor5.0
RGSC_v3.4	4	162,361,892 - 162,362,144	RGD	RGSC3.4
RGSC_v3.4	4	162,361,893 - 162,362,144	UniSTS	RGSC3.4
Celera	4	147,567,471 - 147,567,722	UniSTS
RGSC_v3.1	4	162,606,829 - 162,607,080	RGD
RH 3.4 Map	4	1002.1	RGD
RH 3.4 Map	4	1002.1	UniSTS

BE120014

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	158,599,853 - 158,600,006 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	158,324,425 - 158,324,577	NCBI	Rnor6.0
Rnor_5.0	4	225,326,862 - 225,327,014	UniSTS	Rnor5.0
RGSC_v3.4	4	161,966,447 - 161,966,599	UniSTS	RGSC3.4
Celera	4	147,325,789 - 147,325,941	UniSTS
RH 3.4 Map	4	1010.7	UniSTS

AU046876

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	4	160,380,990 - 160,381,123 (+)	Marker Load Pipeline
mRatBN7.2	4	158,694,785 - 158,694,918 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	158,418,261 - 158,418,393	NCBI	Rnor6.0
Rnor_5.0	4	225,420,347 - 225,420,479	UniSTS	Rnor5.0
RGSC_v3.4	4	162,063,311 - 162,063,443	UniSTS	RGSC3.4
Celera	4	147,420,902 - 147,421,036	UniSTS

RH139336

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	158,741,748 - 158,741,980 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	158,466,018 - 158,466,249	NCBI	Rnor6.0
Rnor_5.0	4	225,468,104 - 225,468,335	UniSTS	Rnor5.0
RGSC_v3.4	4	162,110,276 - 162,110,507	UniSTS	RGSC3.4
Celera	4	147,467,848 - 147,468,079	UniSTS
RH 3.4 Map	4	348.11	UniSTS

AU049195

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	158,822,360 - 158,822,615 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	158,545,629 - 158,545,883	NCBI	Rnor6.0
Rnor_5.0	4	225,547,527 - 225,547,781	UniSTS	Rnor5.0
RGSC_v3.4	4	162,342,880 - 162,343,134	UniSTS	RGSC3.4
Celera	4	147,548,288 - 147,548,542	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
14	11	64	136	68	69	39	24	39	6	249	117	9	111	71	72	30	13	13

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003753944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000032112 ⟹ ENSRNOP00000030034

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,200,988 - 160,541,821 (+)	Ensembl
mRatBN7.2 Ensembl	4	158,514,857 - 158,855,651 (+)	Ensembl
Rnor_6.0 Ensembl	4	158,243,086 - 158,576,978 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078495 ⟹ ENSRNOP00000068994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,201,245 - 160,541,821 (+)	Ensembl
mRatBN7.2 Ensembl	4	158,514,857 - 158,855,651 (+)	Ensembl
Rnor_6.0 Ensembl	4	158,224,000 - 158,576,978 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084240 ⟹ ENSRNOP00000070208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,182,152 - 160,541,821 (+)	Ensembl
mRatBN7.2 Ensembl	4	158,496,014 - 158,855,651 (+)	Ensembl
Rnor_6.0 Ensembl	4	158,224,000 - 158,576,978 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119671 ⟹ ENSRNOP00000090974

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,201,576 - 160,541,821 (+)	Ensembl
mRatBN7.2 Ensembl	4	158,514,861 - 158,855,651 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134851 ⟹ ENSRNOP00000103618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,201,348 - 160,541,821 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000158865 ⟹ ENSRNOP00000103720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	160,201,355 - 160,541,821 (+)	Ensembl

RefSeq Acc Id:

XM_017593038 ⟹ XP_017448527

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	160,200,471 - 160,541,830 (+)	NCBI
mRatBN7.2	4	158,514,201 - 158,855,639 (+)	NCBI
Rnor_6.0	4	158,222,650 - 158,577,595 (+)	NCBI

Sequence:

show sequence

CAGAAAGTACCCAGGGCAGCTCGTAAACGTGTTTTAGGGGAGTGTCATGGAAAAACTCCTTGGG
GAAGGATAGAAGAAGAATGGATAAGGAGCAGTGGTGGGCGGGCACCTTTTTATTCCTTTAGGAA
TGAGAGGGCATGGAGAAGGGTCCCTGGAAGCAGGAAGAAGGTGAAGGAAGGAGAATGAAAGGGA
AAAGAGGGAGAGAGATGCGGAAGTGCAAGGTGTTCTGAGCCGGGACATGAGACACTGAGTAGGC
TGCTTGCTTTGGAACCGGAGACACACAGACTGGAGTCGCTTCACGTGTAAAATGGATAAATGGA
AGTCGTTGCCCCACAGACTGGAGATCGAGGCTGAAGTATGAACACTGGGCCAAGCAAAGCACTT
GAGAGACAGCAGTCAGAGTTTTAGATGATCGGCAGCCATTAATCCTGGAGGTGTACAGAGTAAA
GCCTCGAGGCTGGCCCGATGCTTTCTGTTTCCCTTCATTCTGTTGCGCTTCTGCCACTGTCTTC
TGTAGAGCGGGGAGCAGACATCTCTGATTCAGTGATCACAGACATCGCCCTTGATGCTGACATG
TTGCTTTCCCATAGAGGAGGCACAGTATCAGGGAGCATCAGTTGCTTCTGGCATCTTGGCATGC
ATCCCAGGGAATAGTTCTTTGGAGGCTTTCTCTTCACCCCTCTCTCTATGGTCAGGTCCCTAAG
CCACCTTAGGGAGGCCTACATTACTCTTGTCCCACAGCTTAACTTCTAGGCACATTCCTTACTG
CCCTAGACACTCCTGCGGAAGCTCAAACGAACACGTGCCCTCTCCCCTCTGCCCTTCGTTCTTG
TGTTCAGACCGCAGCTGGAGTAGAGTATGTGAAGAGACCTCATTGTGCTGTTTCAGTGCCTACT
ATTACAACTCAGGGCTGTAGCCTGCAGCCTGGTGCCACGGGAAGGAGACTTCACTGGGGACTCC
AAACTAATCAGCCAGGCGGTTCACGAGATAAGCCGGCTGAATTATCACAGGCCAGCGGGCTGTG
TGGCGCTCACTCAGGCTCCCTCATCTGGAGGAGCGCCAGCAGCATTTACTCCCTGGCCCGCAGC
CCATGCCTGATCCCAGCGTGTCAACTGCTGCACCTGAGAGTGGGATCCTTTCTGGAAGTCGGGA
CGCAGGAGGAGTGCGGGAGGAGACTGCGGAGGGAGAGGAATGGATTGGAGGAGGTGGCAGCCGC
TGGAGGGGCGGGCACATCCAGACAAGCTGAGCCGCGATGGAATTAACTCCCTGGCAGCCACATA
AGCCTGCCCAGAGTGGAGCGAGGGCGGCCAAGGGCCACCAGTTGGGGCTTGGCGTCTGGGGACC
AGCACCATGGCGGCCCCTGGGCTGCAAGACATCCCTCTGCTCCCTGGATCTCCACGTCGGCTGA
GTTCACGGACAATGGCAAGAGGAAGCCAGGGCCCCAGACATGGACAGCAGTACCTCAAGGTGCC
CGGTCCCCGGCTCCCAGGTCAGAGGGACAATTCTAGCCTACACCCTAGCCAGGTCTCCAGGAGA
GAGAGTTCCCGAGACCGTTCTGTCATCAATAACTACCTGGATGCCAATGAGCCTGCATCCTCAG
AAGCCCGTCTGAGCCGCATGCACTTTCACGACAACCAGAGGAAAGTCGATTATGTCCTTGCATA
CCACTACCGGAAGCGAGGCGCACACCTGGGCCATGGCTCCCCTGGACACTCGCTGGCTGTTATC
TCCAATGGGGAGACAGGCAAGGAGCGGCATGGTGGGGGCCCTGGCGATATTGAACTTGGGCCAC
TGGACGCTCTCGAAGAGGAAAGGAGGGAGCAGCGAGATGAATTTGAGCACAACCTGATGGCAGC
TGGGCTGGAGCTGGAGAAGGACTTGGAGAGCAAAAGCCAGGGATCTGTCTTTGTCCGGATCCAC
GCCCCATGGCAGGTGCTGGCCAGGGAAGCAGAGTTCTTGAAGATCAAAGTCCCTACCAAGAAAA
TGTACGAGATCAAAGCAGGAGGAAGCATCGCAAAGAAGTTCAGCGCCATTCTGCAGACGCTTAG
CTCACCGCTGCAGCCCAGAGTTCCTGAACACAGCAACAACAGGATGAAAAACCTCTCCTACCCG
TTCTCCAGGGAAAAAATGTACCTGTACAACATCCAGGAAAAGGACGCCTTCTTTGACAATGCTA
CCCGGAGCCGCATTGTACATGAAATTCTGAAGCGGACAGCCTGTTCTCGAGCCAACAACACGAT
GGGCATTAACTCTCTAATAGCGAACAATATCTATGAGGCTGCCTACCCGCTCCATGATGGTGAA
TATGACAGTCCAGGGGATGACATGAATGACAGAAAGTTGCTGTATCAGGAATGGGCACGCTATG
GAGTGTTTTACAAATTTCAACCCATTGACCTCATCAGGAAGTATTTTGGAGAGAAAATTGGGCT
ATATTTTGCTTGGCTGGGGTTGTATACATCATTCCTGATCCCATCTTCTGTCATTGGAGTGATT
GTGTTTCTTTATGGATGTGCAACAATCGAGGAAGATATTCCCAGCAAAGAGATGTGTGACCACC
AGAATGCCTTCACCATGTGTCCCCTGTGTGACAAATCCTGTGACTATTGGAACCTCAGCTCAGC
CTGTGGGACCGCACGGGCCAGTCATCTGTTTGACAATCCAGCCACTGTCTTCTTTTCCATCTTC
ATGGCTCTGTGGGCTACCATGTTTCTGGAAAACTGGAAAAGACTCCAGATGCGCTTGGGTTACT
TCTGGGACCTGACTGGGATAGAAGAGGAAGAAGAACACTCCCGGCCTGAATATGAGACCAAAGT
ACGAGAGAAACTGCTAAAGGAGAGTGGCAAGTCTGCGGTCCAGAAGCTGGAAGCGAACTCACCT
GAGGACGATGAGGATGATGAAGATAAACTGACTTGGAAAGACCGTTTCCCAGGATACTTGATGA
ACTCTGTCTCCATCTTGTTTATGATCGCCCTGACGTTCTCCATTGTCTTTGGGGTCATTGTCTA
TCGGATCACAACTGCAGCTGCTCTGTCCCTCAACAAGGCTACACGCTCCAACGTCCGGGTGACA
GTGACTGCAACAGCGGTCATCATCAACCTCGTGGTCATCCTCATCTTGGATGAGATCTATGGCG
CTGTGGCCAAGTGGCTTACCAAAATCGAGGTTCCGAAAACAGAACAGACTTTTGAAGAACGATT
GATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCTCCCATCTTCTATGTGGCCTTT
TTCAAGGGGAGGTTTGTGGGCAGACCTGGAAGCTATGTCTATGTGTTCGACGGTTACCGCATGG
AAGAGTGCGCTCCGGGAGGCTGTCTCATGGAGCTGTGTATACAGCTCAGCATCATCATGTTGGG
GAAGCAGCTGATCCAGAACAATATCTTTGAGATCGGAGTCCCGAAGCTCAAGAAACTCTTTCGG
AAGCTGAAAGATGAGACAGAACCTGGAGAAAGTGACCCTGACCACTCAAAACGTCCAGAGCAGT
GGGACCTCGACTACAGCCTAGAGCCTTACACTGGGCTGACTCCTGAGTACATGGAAATGATCAT
CCAGTTTGGTTTTGTCACCCTTTTTGTGGCCTCCTTTCCTCTGGCCCCCGTGTTTGCCCTCCTC
AACAATGTCATCGAAGTGCGGCTGGATGCAAAAAAGTTTGTTACAGAGCTGAGACGCCCAGATG
CTGTGAGGACCAAAGACATTGGAATTTGGTTTGACATTCTCTCCGGAATTGGCAAGTTCTCAGT
CATCATCAATGCTTTTGTCATTGCTGTCACCTCCGACTTTATCCCCCGCCTTGTATACCAGTAC
TCCTATAGCCACAACGGGACGCTACATGGATTCGTGAACCATACACTCTCCTTTTTCAACGTCA
GCCAGCTGAAGGAGGGGACACAGCCAGAAAACTCACAGTTCGACCAGGAGGTTCAGTTTTGCAG
GTTCAAAGATTATCGAGAGCCACCCTGGGCACCAAACCCATATGAGTTTTCCAAGCAGTACTGG
TCTGTTCTGTCTGCCCGTCTGGCCTTTGTCATCATCTTCCAGAATCTAGTGATGTTCCTGAGTG
TCCTCGTGGACTGGATGATTCCAGATATTCCGACAGACATCAGCGACCAGATCAAGAAGGAGAA
GAGCTTGTTGGTAGACTTTTTCCTGAAGGAGGAACATGAGAAGGTCAAGCTGGCCGATGAGCCT
GCCCAGAGGAGCCAGGGAGGTGGGAATAGGAGCAGGAGGAGCCGTGCAGCCAGCTCTGCACCAT
CAGGCCGGAGCCAGCCAGGCAGCATAGCATCCTCAGGGTCCCAGCACACCAACGTATGAGCCCG
GCGTTGGCAGCAGAGGAGGGCATGTTATAGCGAGACACATGCGCATGCCATATGTTCCTATAAC
ACAGTGGCACACCTCTTCTGCTGGGAACTGGCTTATGGGTGTCTCCAAAAGGAAGTTACAGAAA
GGGAAATAGAACGAGAGCGTGCAGGACGGAAGGGAACCATACAGCTTCTCAGAAACTGGAAGCT
TCTGTTTCTTTTAGGTCGTCTTTTGAGTTGTGTCCTTTCAGGGAGTTGGTACCCCATGGGGGTT
GCTTCACCATAGAATTCTCTGGGGTTCTTTCTTGTACTTCACCATCATTTTAGGTGAAAGAAGT
AAAGTGAGAGCCCTGTCCGTACTAGCACCCACTATAACTGATCACTACCCCAGTCCTACGGTCA
CCCTGAAATAACCTCTCAGAGACATGTGTGACTGGGACCACTACAAGGCTGGGCAGATGCAAAT
GAAGTTACAGGATGGATTTCCATGGCCGTTGGACCTGGTGGTAAGGAACAACGGTCCTATCCAA
GCTTATCTGCAGCTTGTGTGACAAGGACATATACAATGCAACTAAACACTGTTTTATGCAAGTT
CAGGTTTAAAATAAAATAAATGAAGTCTTTTTT

hide sequence

RefSeq Acc Id:

XM_039108820 ⟹ XP_038964748

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	160,239,503 - 160,541,830 (+)	NCBI
mRatBN7.2	4	158,553,127 - 158,855,639 (+)	NCBI

RefSeq Acc Id:

XM_063286858 ⟹ XP_063142928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	160,201,105 - 160,541,830 (+)	NCBI

RefSeq Acc Id:

XM_063286859 ⟹ XP_063142929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	160,250,627 - 160,541,830 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001418869	(Get FASTA)	NCBI Sequence Viewer
	NP_001418870	(Get FASTA)	NCBI Sequence Viewer
	NP_001418871	(Get FASTA)	NCBI Sequence Viewer
	XP_017448527	(Get FASTA)	NCBI Sequence Viewer
	XP_038964748	(Get FASTA)	NCBI Sequence Viewer
	XP_063142928	(Get FASTA)	NCBI Sequence Viewer
	XP_063142929	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM01841	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030034
	ENSRNOP00000030034.6
	ENSRNOP00000068994.3
	ENSRNOP00000070208
	ENSRNOP00000070208.2
	ENSRNOP00000090974.2
	ENSRNOP00000103618.1
	ENSRNOP00000103720.1

RefSeq Acc Id:	XP_017448527 ⟸ XM_017593038
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2JXB5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAPGLQDIPLLPGSPRRLSSRTMARGSQGPRHGQQYLKVPGPRLPGQRDNSSLHPSQVSRRES SRDRSVINNYLDANEPASSEARLSRMHFHDNQRKVDYVLAYHYRKRGAHLGHGSPGHSLAVISN GETGKERHGGGPGDIELGPLDALEEERREQRDEFEHNLMAAGLELEKDLESKSQGSVFVRIHAP WQVLAREAEFLKIKVPTKKMYEIKAGGSIAKKFSAILQTLSSPLQPRVPEHSNNRMKNLSYPFS REKMYLYNIQEKDAFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYD SPGDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF LYGCATIEEDIPSKEMCDHQNAFTMCPLCDKSCDYWNLSSACGTARASHLFDNPATVFFSIFMA LWATMFLENWKRLQMRLGYFWDLTGIEEEEEHSRPEYETKVREKLLKESGKSAVQKLEANSPED DEDDEDKLTWKDRFPGYLMNSVSILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVT ATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFK GRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKL KDETEPGESDPDHSKRPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNN VIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVIINAFVIAVTSDFIPRLVYQYSY SHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWSV LSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKVKLADEPAQ RSQGGGNRSRRSRAASSAPSGRSQPGSIASSGSQHTNV hide sequence

Ensembl Acc Id:

ENSRNOP00000068994 ⟸ ENSRNOT00000078495

Ensembl Acc Id:

ENSRNOP00000030034 ⟸ ENSRNOT00000032112

Ensembl Acc Id:

ENSRNOP00000070208 ⟸ ENSRNOT00000084240

RefSeq Acc Id:	XP_038964748 ⟸ XM_039108820
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000090974 ⟸ ENSRNOT00000119671

RefSeq Acc Id:	XP_063142928 ⟸ XM_063286858
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063142929 ⟸ XM_063286859
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000103720 ⟸ ENSRNOT00000158865

Ensembl Acc Id:

ENSRNOP00000103618 ⟸ ENSRNOT00000134851

Protein Domains

Anoctamin dimerisation Anoctamin transmembrane

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JXB5-F1-model_v2	AlphaFold	A0A0G2JXB5	1-998	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1591606	AgrOrtholog
BioCyc Gene	G2FUF-42983	BioCyc
Ensembl Genes	ENSRNOG00000023561	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000032112	ENTREZGENE
	ENSRNOT00000032112.7	UniProtKB/TrEMBL
	ENSRNOT00000078495.3	UniProtKB/TrEMBL
	ENSRNOT00000084240	ENTREZGENE
	ENSRNOT00000084240.3	UniProtKB/TrEMBL
	ENSRNOT00000119671.2	UniProtKB/TrEMBL
	ENSRNOT00000134851.1	UniProtKB/TrEMBL
	ENSRNOT00000158865.1	UniProtKB/TrEMBL
InterPro	Anoct_dimer	UniProtKB/TrEMBL
	Anoctamin	UniProtKB/TrEMBL
	Anoctamin_TM	UniProtKB/TrEMBL
NCBI Gene	Ano2	ENTREZGENE
PANTHER	PTHR12308	UniProtKB/TrEMBL
	PTHR12308:SF20	UniProtKB/TrEMBL
Pfam	Anoct_dimer	UniProtKB/TrEMBL
	Anoctamin	UniProtKB/TrEMBL
PhenoGen	Ano2	PhenoGen
RatGTEx	ENSRNOG00000023561	RatGTEx
UniProt	A0A0G2JU76	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2JXB5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJA0	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L3F3_RAT	UniProtKB/TrEMBL
	A0ABK0LE35_RAT	UniProtKB/TrEMBL
	F1M3G8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-15	Ano2	anoctamin 2	Ano2	anoctamin 2, calcium activated chloride channel	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-11-24	Ano2	anoctamin 2, calcium activated chloride channel	LOC100361584	anoctamin 2-like	Data merged from RGD:2319885	737654	APPROVED
2015-11-24	Ano2	anoctamin 2, calcium activated chloride channel	Ano2	anoctamin 2, calcium activated chloride channel	Type changed (type changed from [null] to [protein-coding])	629549	APPROVED
2015-07-29	LOC100361584	anoctamin 2-like	LOC100912468	anoctamin-2-like	Data merged from RGD:6486491	737654	PROVISIONAL
2014-04-16	Ano2	anoctamin 2, calcium activated chloride channel	Ano2	anoctamin 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100912468	anoctamin-2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-05-13	Ano2	anoctamin 2	LOC683001	similar to Transmembrane protein 16B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	LOC100361584	anoctamin 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC683001	similar to Transmembrane protein 16B			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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