Advanced Search (OLGA)

Gene: Gpr17 (G protein-coupled receptor 17) Rattus norvegicus

Analyze

Symbol:

Gpr17

Name:

G protein-coupled receptor 17

RGD ID:

1589785

Description:

Enables receptor serine/threonine kinase binding activity. Involved in oligodendrocyte differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human GPR17 (G protein-coupled receptor 17); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diethylstilbestrol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

G-protein coupled receptor 17; UDP/CysLT receptor; uracil nucleotide/cysteinyl leukotriene receptor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR17 (G protein-coupled receptor 17)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gpr17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gpr17 (G protein-coupled receptor 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPR17 (G protein-coupled receptor 17)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GPR17 (G protein-coupled receptor 17)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr17 (G protein-coupled receptor 17)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr17 (G protein-coupled receptor 17)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr17 (G protein-coupled receptor 17)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr17 (G protein-coupled receptor 17)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-96n2.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	si:dkey-96n2.3	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gnrr-4	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	gpr17	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	23,850,460 - 23,857,381 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	23,850,107 - 23,857,702 (-)	Ensembl				GRCr8
mRatBN7.2	18	23,576,232 - 23,583,153 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	23,577,242 - 23,582,966 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	23,708,403 - 23,709,422 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	24,457,393 - 24,458,412 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	23,803,373 - 23,804,392 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	24,733,306 - 24,739,194 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	24,734,330 - 24,735,349 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	24,446,883 - 24,453,499 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	24,374,253 - 24,375,272 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	23,332,880 - 23,333,899 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

brain infarction (ISO)

Hypercholesterolemia (ISO)

Insulin Resistance (ISO)

Metabolic Syndrome (ISO)

obesity (ISO)

Pediatric Obesity (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cangrelor (ISO)

captan (ISO)

CGP 52608 (ISO)

clobetasol (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

diethylstilbestrol (EXP)

dimethylarsinic acid (ISO)

enniatin (ISO)

esketamine (ISO)

ethanol (ISO)

folpet (ISO)

fulvestrant (ISO)

furan (EXP)

ketoconazole (EXP)

leukotriene C4 (ISO)

leukotriene D4 (ISO)

leukotriene E4 (ISO)

methamphetamine (EXP)

methylarsonic acid (ISO)

montelukast (ISO)

ochratoxin A (ISO)

orphenadrine (EXP)

paracetamol (ISO)

progesterone (ISO)

resveratrol (ISO)

rotenone (EXP)

sevoflurane (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

triptonide (ISO)

trovafloxacin (ISO)

UDP (ISO)

UDP-alpha-D-galactose (ISO)

UDP-alpha-D-glucose (ISO)

UDP-D-galactose (ISO)

UDP-D-glucose (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IBA,IEA)

negative regulation of inflammatory response to antigenic stimulus (ISO)

oligodendrocyte differentiation (IEP)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IBA,IEA)

protein binding (ISO)

receptor serine/threonine kinase binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Does GRK-ß arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?	Daniele S, etal., Cell Signal. 2014 Jun;26(6):1310-25. doi: 10.1016/j.cellsig.2014.02.016. Epub 2014 Mar 5.
2.	The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization.	Fumagalli M, etal., Glia. 2015 Dec;63(12):2327-39. doi: 10.1002/glia.22896. Epub 2015 Jul 31.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16990797	PMID:20056144	PMID:20574000	PMID:21209081	PMID:22155652	PMID:23288840	PMID:24150254	PMID:26506265	PMID:26620557	PMID:27544384	PMID:28254957	PMID:29187582
PMID:30226562	PMID:32387084	PMID:34569901	PMID:34769111

Genomics

Comparative Map Data

Gpr17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	23,850,460 - 23,857,381 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	23,850,107 - 23,857,702 (-)	Ensembl				GRCr8
mRatBN7.2	18	23,576,232 - 23,583,153 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	23,577,242 - 23,582,966 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	23,708,403 - 23,709,422 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	24,457,393 - 24,458,412 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	23,803,373 - 23,804,392 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	24,733,306 - 24,739,194 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	24,734,330 - 24,735,349 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	24,446,883 - 24,453,499 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	24,374,253 - 24,375,272 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	23,332,880 - 23,333,899 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

GPR17
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	127,646,153 - 127,652,639 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	127,645,864 - 127,656,181 (+)	Ensembl			hg38	GRCh38
GRCh37	2	128,403,728 - 128,410,213 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	128,120,217 - 128,126,683 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	128,119,976 - 128,126,442	NCBI
Celera	2	121,714,385 - 121,721,160 (+)	NCBI		Celera
Cytogenetic Map	2	q14.3	NCBI
HuRef	2	120,709,795 - 120,716,458 (+)	NCBI		HuRef
CHM1_1	2	128,407,871 - 128,414,621 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	128,081,407 - 128,087,893 (+)	NCBI		T2T-CHM13v2.0

Gpr17
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	32,076,052 - 32,082,925 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	32,076,050 - 32,082,689 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	31,942,999 - 31,949,890 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	31,942,997 - 31,949,636 (-)	Ensembl			mm10	GRCm38
MGSCv37	18	32,102,653 - 32,109,290 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	32,086,024 - 32,092,646 (-)	NCBI		MGSCv36	mm8
Celera	18	32,433,365 - 32,440,002 (-)	NCBI		Celera
Cytogenetic Map	18	B1	NCBI
cM Map	18	17.89	NCBI

Gpr17
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955459	2,890,266 - 2,903,053 (-)	Ensembl
ChiLan1.0	NW_004955459	2,890,266 - 2,903,053 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR17
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	47,991,565 - 47,999,056 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	48,006,543 - 48,013,269 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	32,623,444 - 32,630,256 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	128,312,116 - 128,319,177 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	128,316,464 - 128,321,519 (+)	Ensembl			panPan2	panpan1.1

GPR17
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	22,958,778 - 22,968,489 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	22,963,363 - 22,964,382 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	23,205,988 - 23,215,825 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	24,284,819 - 24,294,651 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	24,284,851 - 24,294,483 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	22,988,450 - 22,998,293 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	23,183,202 - 23,193,039 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	24,315,107 - 24,324,942 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gpr17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	97,960,251 - 97,968,807 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	43,653,481 - 43,654,497 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	43,652,244 - 43,656,661 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR17
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	59,692,996 - 59,701,265 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	59,692,992 - 59,702,513 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	66,443,203 - 66,448,850 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR17
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	2,564,156 - 2,571,442 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666061	20,189,037 - 20,195,643 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr17
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	14,115,325 - 14,128,169 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624732	14,115,267 - 14,129,714 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpr17
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	12,287,971 - 12,290,159 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gpr17
18 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	57
Count of miRNA genes:	51
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000036537
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	12219237	26822399	Rat
2301409	Cm70	Cardiac mass QTL 70		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	18	7065728	52065728	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	22015562	61600538	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	15642280	31610627	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	12216684	31644508	Rat
12904716	Am21	Aortic mass QTL 21		0.005	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	7065728	52065728	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	26032889	Rat
12904714	Cm131	Cardiac mass QTL 131		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	7065728	52065728	Rat
12904715	Cm132	Cardiac mass QTL 132		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	7065728	52065728	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	1	25071266	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	15226101	42690662	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5460455	42690191	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	12216684	31644508	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	31610627	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	12219237	26822399	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	1	25022372	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	12219237	26822399	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	12219237	26822399	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	12219237	26822399	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	12219237	26822399	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	12219237	26822399	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	26032889	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4482648	49482648	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
11565454	Kidm59	Kidney mass QTL 59		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	7065728	52065728	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
14	11	51	150	56	55	25	34	25	6	226	117	10	129	62	82	30	5	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001071777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ777767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036537 ⟹ ENSRNOP00000032046

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	24,734,330 - 24,735,349 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104846 ⟹ ENSRNOP00000091710

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	23,850,107 - 23,857,702 (-)	Ensembl
mRatBN7.2 Ensembl	18	23,577,242 - 23,582,966 (-)	Ensembl

RefSeq Acc Id:

NM_001071777 ⟹ NP_001065245

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	23,850,460 - 23,857,381 (-)	NCBI
mRatBN7.2	18	23,576,232 - 23,583,153 (-)	NCBI
Rnor_6.0	18	24,734,330 - 24,735,349 (-)	NCBI
Rnor_5.0	18	24,446,883 - 24,453,499 (-)	NCBI
RGSC_v3.4	18	24,374,253 - 24,375,272 (-)	RGD
Celera	18	23,332,880 - 23,333,899 (-)	RGD

Sequence:

show sequence

ATGGATGGCCTCGAGACAGCCCTACCGAGTCTGACTGACAATGCCTCCCTGGCTTACTCTGAAC
AATGTGGCCAAGAGACGCCCCTGGAGAACATGCTCTTCGCCTGCTTCTACCTCCTGGACTTCAT
CCTAGCTTTTGTGGGCAACGCTCTGGCCCTCTGGCTTTTCATCTGGGATCACAAGTCAGGCACT
CCGGCCAACGTGTTCCTAATGCACCTGGCTGTGGCCGACTTGTCCTGTGTGCTGGTCCTGCCTA
CCCGGTTGGTTTATCACTTCTCTGGCAATCACTGGCCTTTTGGGGAAATCCCGTGCCGACTCAC
TGGCTTCCTCTTCTACCTGAATATGTACGCCAGCATCTACTTCCTCACCTGCATCAGTGCTGAC
CGGTTCCTGGCCATTGTGCACCCAGTCAAGTCCCTCAAGCTTCGAAGACCTCTCTATGCCCACC
TGGCCTGCGCCTTCCTGTGGATCGTGGTGGCCGTGGCTATGGCCCCACTGCTAGTGAGTCCGCA
GACTGTGCAGACCAACCACACGGTTGTCTGCCTGCAACTGTACCGGGAGAAGGCCTCCCATCAT
GCCCTGGCTTCCCTGGCTGTGGCTTTTACCTTCCCCTTCATCACCACGGTCACCTGCTACCTGC
TGATCATTCGCAGCCTCCGCCAGGGTCCCCGTATAGAGAAGCACCTCAAGAATAAAGCCGTCCG
CATGATTGCTATGGTTCTGGCCATCTTCCTGATTTGTTTTGTGCCCTACCACATCCACCGTTCA
GTCTATGTGCTTCACTACCGCGGTGGTGGGACTTCGTGCTCAGCTCAGCGTGCCCTGGCCCTAG
GGAACCGGATCACCTCCTGCCTCACCAGCCTCAACGGGGCCCTGGATCCAGTCATGTACTTCTT
TGTGGCTGAGAAATTCCGCCACGCCTTGTGCAACTTGCTCTGCAGCAAACGACTCACAGGTCCT
CCTCCCAGCTTTGAAGGGAAAACCAACGAGAGCTCCCTGAGCGCTCGGTCTGAGCTGTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001065245	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABG75921	(Get FASTA)	NCBI Sequence Viewer
	EDL76180	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000091710
	ENSRNOP00000091710.1
GenBank Protein	Q09QM4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001065245 ⟸ NM_001071777

- UniProtKB:

Q09QM4 (UniProtKB/Swiss-Prot), A6J2P8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDGLETALPSLTDNASLAYSEQCGQETPLENMLFACFYLLDFILAFVGNALALWLFIWDHKSGT
PANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISAD
RFLAIVHPVKSLKLRRPLYAHLACAFLWIVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHH
ALASLAVAFTFPFITTVTCYLLIIRSLRQGPRIEKHLKNKAVRMIAMVLAIFLICFVPYHIHRS
VYVLHYRGGGTSCSAQRALALGNRITSCLTSLNGALDPVMYFFVAEKFRHALCNLLCSKRLTGP
PPSFEGKTNESSLSARSEL

hide sequence

Ensembl Acc Id:

ENSRNOP00000032046 ⟸ ENSRNOT00000036537

Ensembl Acc Id:

ENSRNOP00000091710 ⟸ ENSRNOT00000104846

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q09QM4-F1-model_v2	AlphaFold	Q09QM4	1-339	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589785	AgrOrtholog
BioCyc Gene	G2FUF-8047	BioCyc
Ensembl Genes	ENSRNOG00000025745	Ensembl
	ENSRNOG00000065480	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000104846	ENTREZGENE
	ENSRNOT00000104846.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
KEGG Report	rno:767613	UniProtKB/Swiss-Prot
NCBI Gene	767613	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/Swiss-Prot
	URACIL NUCLEOTIDE/CYSTEINYL LEUKOTRIENE RECEPTOR	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PhenoGen	Gpr17	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot
	P2YPURNOCPTR	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000025745	RatGTEx
	ENSRNOG00000065480	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	A6J2P8	ENTREZGENE, UniProtKB/TrEMBL
	GPR17_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-11-20	Gpr17	G protein-coupled receptor 17			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - CTD