Tspan7 (tetraspanin 7) - Rat Genome Database

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Gene: Tspan7 (tetraspanin 7) Rattus norvegicus
Analyze
Symbol: Tspan7
Name: tetraspanin 7
RGD ID: 1589725
Description: Involved in regulation of postsynaptic neurotransmitter receptor internalization. Is active in postsynapse. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 58. Orthologous to human TSPAN7 (tetraspanin 7); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A15; DXS1692E; MXS1; neuroprotective protein 5; TALLA-1; tetraspanin-7; Tm4sf2; Tm4sf2_mapped; transmembrane 4 superfamily member 2; transmembrane 4 superfamily member 2 (mapped); Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X14,881,327 - 14,978,627 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX14,881,334 - 14,978,655 (-)EnsemblGRCr8
mRatBN7.2X12,208,783 - 12,306,092 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX12,208,783 - 12,306,131 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX12,393,035 - 12,490,273 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X15,889,994 - 15,987,224 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X12,146,537 - 12,243,766 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X13,261,551 - 13,282,886 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX13,261,558 - 13,279,099 (-)Ensemblrn6Rnor6.0
Rnor_5.0X14,051,176 - 14,071,673 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X24,362,332 - 24,383,176 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX12,822,161 - 12,919,359 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
antimony(0)  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dibutyl phthalate  (EXP)
dioxygen  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
glucose  (EXP)
hydrogen peroxide  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(II) chloride  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
nickel sulfate  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
potassium dichromate  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking. Bassani S, etal., Neuron. 2012 Mar 22;73(6):1143-58. doi: 10.1016/j.neuron.2012.01.021. Epub 2012 Mar 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes. Kuroiwa A, etal., Cytogenet Cell Genet 1998;81(3-4):208-12.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21124846   PMID:36625203  


Genomics

Comparative Map Data
Tspan7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X14,881,327 - 14,978,627 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX14,881,334 - 14,978,655 (-)EnsemblGRCr8
mRatBN7.2X12,208,783 - 12,306,092 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX12,208,783 - 12,306,131 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX12,393,035 - 12,490,273 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X15,889,994 - 15,987,224 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X12,146,537 - 12,243,766 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X13,261,551 - 13,282,886 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX13,261,558 - 13,279,099 (-)Ensemblrn6Rnor6.0
Rnor_5.0X14,051,176 - 14,071,673 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X24,362,332 - 24,383,176 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX12,822,161 - 12,919,359 (-)NCBICelera
Cytogenetic MapXq12NCBI
TSPAN7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X38,561,542 - 38,688,918 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX38,561,498 - 38,689,249 (+)Ensemblhg38GRCh38
GRCh37X38,420,795 - 38,548,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X38,305,683 - 38,433,116 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X38,176,955 - 38,304,388NCBI
CeleraX42,558,371 - 42,685,804 (+)NCBICelera
Cytogenetic MapXp11.4NCBI
HuRefX36,165,283 - 36,292,541 (+)NCBIHuRef
CHM1_1X38,451,822 - 38,579,246 (+)NCBICHM1_1
T2T-CHM13v2.0X37,965,162 - 38,092,516 (+)NCBIT2T-CHM13v2.0
Tspan7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X10,351,355 - 10,462,843 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX10,351,397 - 10,462,844 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X10,485,116 - 10,596,604 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX10,485,158 - 10,596,605 (+)Ensemblmm10GRCm38
MGSCv37X10,062,242 - 10,173,730 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X9,642,075 - 9,753,563 (+)NCBIMGSCv36mm8
CeleraX8,190,531 - 8,300,146 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.85NCBI
Tspan7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495556675,576 - 206,827 (+)Ensembl
ChiLan1.0NW_00495556675,576 - 203,512 (+)NCBIChiLan1.0ChiLan1.0
TSPAN7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X40,204,812 - 40,332,367 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X40,208,172 - 40,335,748 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X31,006,297 - 31,133,856 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X38,818,523 - 38,841,328 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX38,714,162 - 38,841,328 (+)EnsemblpanPan2panpan1.1
TSPAN7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X33,336,821 - 33,465,097 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX33,336,846 - 33,464,163 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX20,686,033 - 20,814,156 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X33,386,892 - 33,515,069 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX33,386,871 - 33,515,066 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X33,465,894 - 33,593,915 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X33,437,798 - 33,565,917 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X33,479,723 - 33,608,321 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tspan7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X25,575,743 - 25,698,159 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365025,416,454 - 5,538,905 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365025,416,454 - 5,538,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX34,522,933 - 34,660,212 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X34,522,899 - 34,660,216 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X38,595,834 - 38,624,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X35,711,603 - 35,829,385 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX35,711,601 - 35,829,681 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666076896,882 - 1,015,532 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476216,768,758 - 16,911,804 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476216,767,493 - 16,911,713 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tspan7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X10,683,062 - 10,783,747 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tspan7
302 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:747
Count of miRNA genes:256
Interacting mature miRNAs:316
Transcripts:ENSRNOT00000051898, ENSRNOT00000060857
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X400149324470521Rat

Markers in Region
RH140128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X12,208,897 - 12,209,097 (+)MAPPERmRatBN7.2
Rnor_6.0X13,261,666 - 13,261,865NCBIRnor6.0
Rnor_5.0X14,051,291 - 14,051,490UniSTSRnor5.0
RGSC_v3.4X24,362,447 - 24,362,646UniSTSRGSC3.4
CeleraX12,822,276 - 12,822,475UniSTS
RH 3.4 MapX99.4UniSTS
Cytogenetic MapXq13UniSTS
RH128988  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X12,208,805 - 12,208,970 (+)MAPPERmRatBN7.2
Rnor_6.0X13,261,574 - 13,261,738NCBIRnor6.0
Rnor_5.0X14,051,199 - 14,051,363UniSTSRnor5.0
RGSC_v3.4X24,362,355 - 24,362,519UniSTSRGSC3.4
CeleraX12,822,184 - 12,822,348UniSTS
RH 3.4 MapX87.1UniSTS
Cytogenetic MapXq13UniSTS
BE097059  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X12,239,413 - 12,239,580 (+)MAPPERmRatBN7.2
Rnor_6.0X13,292,690 - 13,292,856NCBIRnor6.0
Rnor_5.0X14,081,477 - 14,081,643UniSTSRnor5.0
RGSC_v3.4X24,392,980 - 24,393,146UniSTSRGSC3.4
CeleraX12,852,731 - 12,852,897UniSTS
RH 3.4 MapX95.9UniSTS
Cytogenetic MapXq13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 51 59 6 315 151 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000051898   ⟹   ENSRNOP00000048893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX12,208,783 - 12,306,101 (-)Ensembl
Rnor_6.0 EnsemblX13,262,791 - 13,279,082 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000060857   ⟹   ENSRNOP00000057580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX14,881,334 - 14,978,655 (-)Ensembl
mRatBN7.2 EnsemblX12,208,783 - 12,306,131 (-)Ensembl
Rnor_6.0 EnsemblX13,261,558 - 13,279,099 (-)Ensembl
RefSeq Acc Id: NM_001398737   ⟹   NP_001385666
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X14,881,327 - 14,978,627 (-)NCBI
mRatBN7.2X12,208,783 - 12,306,092 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001385666 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58793 (Get FASTA)   NCBI Sequence Viewer  
  ABX10436 (Get FASTA)   NCBI Sequence Viewer  
  EDL97621 (Get FASTA)   NCBI Sequence Viewer  
  EDL97622 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057580
  ENSRNOP00000057580.5
Ensembl Acc Id: ENSRNOP00000057580   ⟸   ENSRNOT00000060857
Ensembl Acc Id: ENSRNOP00000048893   ⟸   ENSRNOT00000051898
RefSeq Acc Id: NP_001385666   ⟸   NM_001398737
- UniProtKB: B3STU1 (UniProtKB/TrEMBL),   F1M9I6 (UniProtKB/TrEMBL),   B0BNE7 (UniProtKB/TrEMBL),   A0A9K3Y7X8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9I6-F1-model_v2 AlphaFold F1M9I6 1-244 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701716
Promoter ID:EPDNEW_R12240
Type:single initiation site
Name:Tspan7_1
Description:tetraspanin 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X13,279,016 - 13,279,076EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589725 AgrOrtholog
BioCyc Gene G2FUF-3034 BioCyc
Ensembl Genes ENSRNOG00000003229 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060857 ENTREZGENE
  ENSRNOT00000060857.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122763 IMAGE-MGC_LOAD
  IMAGE:7312115 IMAGE-MGC_LOAD
InterPro Tetraspanin UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2 UniProtKB/TrEMBL
  Tetraspanin_subgr UniProtKB/TrEMBL
  TSN6/7_LEL UniProtKB/TrEMBL
MGC_CLONE MGC:188170 IMAGE-MGC_LOAD
  MGC:95030 IMAGE-MGC_LOAD
NCBI Gene 363447 ENTREZGENE
PANTHER PTHR19282 UniProtKB/TrEMBL
  TETRASPANIN-7 UniProtKB/TrEMBL
Pfam Tetraspannin UniProtKB/TrEMBL
PhenoGen Tspan7 PhenoGen
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003229 RatGTEx
Superfamily-SCOP Tetraspanin UniProtKB/TrEMBL
UniProt A0A9K3Y7X8 ENTREZGENE, UniProtKB/TrEMBL
  A6K013_RAT UniProtKB/TrEMBL
  B0BNE7 ENTREZGENE, UniProtKB/TrEMBL
  B3STU1 ENTREZGENE, UniProtKB/TrEMBL
  F1M9I6 ENTREZGENE
UniProt Secondary F1M9I6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Tspan7  tetraspanin 7  Tm4sf2  transmembrane 4 superfamily member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   transmembrane 4 superfamily member 2  Tm4sf2  transmembrane 4 superfamily member 2 (mapped)  Name updated 737654 APPROVED
2007-04-12 Tm4sf2  transmembrane 4 superfamily member 2 (mapped)  Tm4sf2_mapped  transmembrane 4 superfamily member 2 (mapped)  Data merged from RGD:3873 737654 APPROVED
2006-11-19 Tm4sf2  transmembrane 4 superfamily member 2 (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Tm4sf2_mapped  transmembrane 4 superfamily member 2 (mapped)  Tm4sf2  transmembrane 4 superfamily member 2  Symbol and Name updated 1556543 APPROVED
2003-04-09 Tm4sf2  transmembrane 4 superfamily member 2    Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15)  Name updated 629478 APPROVED
2002-06-10 Tm4sf2  Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15)      Symbol and Name status set to approved 70586 APPROVED