Crtc1 (CREB regulated transcription coactivator 1) - Rat Genome Database

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Gene: Crtc1 (CREB regulated transcription coactivator 1) Rattus norvegicus
Analyze
Symbol: Crtc1
Name: CREB regulated transcription coactivator 1
RGD ID: 1589158
Description: Predicted to enable cAMP response element binding protein binding activity and transcription coactivator activity. Involved in positive regulation of dendrite development; positive regulation of long-term synaptic potentiation; and postsynapse to nucleus signaling pathway. Located in dendrite and neuronal cell body. Is active in glutamatergic synapse and postsynaptic density. Biomarker of middle cerebral artery infarction. Orthologous to human CRTC1 (CREB regulated transcription coactivator 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CREB-regulated transcription coactivator 1; LOC361125; Mect1; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1 homolog; TORC-1; TORC1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,022,171 - 19,080,880 (+)NCBIGRCr8
mRatBN7.21618,988,197 - 19,046,914 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,988,250 - 19,043,381 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,029,889 - 19,082,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,162,430 - 20,215,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,082,848 - 19,135,617 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,740,746 - 20,798,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,740,826 - 20,794,039 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,593,102 - 20,649,007 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,494,580 - 19,536,787 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1619,179,611 - 19,233,207 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)
dendrite  (IDA)
glutamatergic synapse  (EXP,IDA,IEP,IMP)
neuronal cell body  (IDA)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO,ISS)
plasma membrane  (IEA,ISO)
postsynaptic density  (IDA,IEP)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Activity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleus. Ch'ng TH, etal., Cell. 2012 Jul 6;150(1):207-21. doi: 10.1016/j.cell.2012.05.027.
2. Cellular mechanisms underlying the regulation of dendritic development by hepatocyte growth factor. Finsterwald C and Martin JL, Eur J Neurosci. 2011 Oct;34(7):1053-61. doi: 10.1111/j.1460-9568.2011.07839.x. Epub 2011 Sep 6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke. Liu L, etal., Brain Res Bull. 2010 May 31;82(3-4):228-33. Epub 2010 Apr 24.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Requirement of TORC1 for late-phase long-term potentiation in the hippocampus. Zhou Y, etal., PLoS One. 2006 Dec 20;1:e16.
Additional References at PubMed
PMID:14506290   PMID:14536081   PMID:17360587   PMID:19244510   PMID:19356686   PMID:19734865   PMID:20639200   PMID:20660299   PMID:21504792   PMID:21679259   PMID:23223304   PMID:23751872  
PMID:23993098   PMID:26032503   PMID:26210066   PMID:26440419   PMID:26759481   PMID:26844388   PMID:27383213   PMID:27766766   PMID:30053369   PMID:31157869   PMID:34274327  


Genomics

Comparative Map Data
Crtc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,022,171 - 19,080,880 (+)NCBIGRCr8
mRatBN7.21618,988,197 - 19,046,914 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,988,250 - 19,043,381 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,029,889 - 19,082,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,162,430 - 20,215,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,082,848 - 19,135,617 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,740,746 - 20,798,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,740,826 - 20,794,039 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,593,102 - 20,649,007 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,494,580 - 19,536,787 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1619,179,611 - 19,233,207 (+)NCBICelera
Cytogenetic Map16p14NCBI
CRTC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,683,680 - 18,782,333 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,683,678 - 18,782,333 (+)EnsemblGRCh38hg38GRCh38
GRCh371918,794,490 - 18,893,143 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,655,425 - 18,754,143 (+)NCBINCBI36Build 36hg18NCBI36
Build 341918,655,424 - 18,749,762NCBI
Celera1918,696,164 - 18,797,938 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,417,854 - 18,457,585 (+)NCBIHuRef
CHM1_11918,853,765 - 18,893,147 (+)NCBICHM1_1
T2T-CHM13v2.01918,818,780 - 18,917,929 (+)NCBIT2T-CHM13v2.0
Crtc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,835,002 - 70,892,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,835,005 - 70,892,229 (-)EnsemblGRCm39 Ensembl
GRCm38870,382,352 - 70,439,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,382,355 - 70,439,579 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,906,257 - 72,963,472 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,311,347 - 73,368,562 (-)NCBIMGSCv36mm8
Celera872,938,781 - 72,996,000 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Crtc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,884,654 - 2,940,815 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,884,654 - 2,940,601 (-)NCBIChiLan1.0ChiLan1.0
CRTC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,543,469 - 23,642,892 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,551,910 - 22,651,377 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,123,375 - 18,221,832 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,131,488 - 19,228,980 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,131,484 - 19,228,980 (+)Ensemblpanpan1.1panPan2
CRTC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,315,021 - 44,394,385 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,319,858 - 44,394,599 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,229,590 - 44,308,964 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,801,223 - 44,880,629 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,801,241 - 44,880,595 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,038,486 - 44,117,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,448,799 - 44,528,003 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,724,092 - 44,803,449 (-)NCBIUU_Cfam_GSD_1.0
Crtc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,002,484 - 203,076,154 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,551,506 - 2,625,327 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,551,621 - 2,625,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRTC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,069,335 - 59,157,176 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,069,334 - 59,157,196 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,823,676 - 58,911,153 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRTC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,146,954 - 17,246,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660742,079,828 - 2,178,896 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crtc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,814,148 - 1,866,915 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,814,079 - 1,868,717 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Crtc1
329 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:136
Count of miRNA genes:98
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000038057
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat

Markers in Region
D16Rat7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,004,435 - 19,004,606 (+)MAPPERmRatBN7.2
Rnor_6.01620,755,556 - 20,755,726NCBIRnor6.0
Rnor_5.01620,607,927 - 20,608,097UniSTSRnor5.0
RGSC_v3.41619,510,773 - 19,510,943UniSTSRGSC3.4
RGSC_v3.41619,510,772 - 19,510,943RGDRGSC3.4
RGSC_v3.11619,510,771 - 19,510,941RGD
Celera1619,194,908 - 19,195,078UniSTS
RH 3.4 Map16236.7RGD
RH 3.4 Map16236.7UniSTS
RH 2.0 Map16246.6RGD
SHRSP x BN Map167.88RGD
FHH x ACI Map1612.1799RGD
Cytogenetic Map16p14UniSTS
D16Kyo1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,997,197 - 18,997,413 (+)MAPPERmRatBN7.2
Rnor_6.01620,748,297 - 20,748,510NCBIRnor6.0
Rnor_5.01620,600,668 - 20,600,881UniSTSRnor5.0
RGSC_v3.41619,503,536 - 19,503,750RGDRGSC3.4
RGSC_v3.41619,503,537 - 19,503,750UniSTSRGSC3.4
RGSC_v3.11619,503,534 - 19,503,748RGD
Celera1619,187,672 - 19,187,885UniSTS
RH 3.4 Map16235.8RGD
RH 3.4 Map16235.8UniSTS
Cytogenetic Map16p14UniSTS
BE102087  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,031,668 - 19,031,839 (+)MAPPERmRatBN7.2
Rnor_6.01620,782,857 - 20,783,027NCBIRnor6.0
Rnor_5.01620,634,812 - 20,634,982UniSTSRnor5.0
RGSC_v3.41619,538,824 - 19,538,994UniSTSRGSC3.4
Celera1619,222,071 - 19,222,241UniSTS
RH 3.4 Map16236.7UniSTS
Cytogenetic Map16p14UniSTS
RH144442  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,003,523 - 19,003,693 (+)MAPPERmRatBN7.2
Rnor_6.01620,754,644 - 20,754,813NCBIRnor6.0
Rnor_5.01620,607,015 - 20,607,184UniSTSRnor5.0
RGSC_v3.41619,509,861 - 19,510,030UniSTSRGSC3.4
Celera1619,193,996 - 19,194,165UniSTS
RH 3.4 Map16223.3UniSTS
Cytogenetic Map16p14UniSTS
BF386683  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,027,264 - 19,027,421 (+)MAPPERmRatBN7.2
Rnor_6.01620,778,449 - 20,778,605NCBIRnor6.0
Rnor_5.01620,630,404 - 20,630,560UniSTSRnor5.0
RGSC_v3.41619,534,420 - 19,534,576UniSTSRGSC3.4
Celera1619,217,681 - 19,217,837UniSTS
RH 3.4 Map16220.4UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000038057   ⟹   ENSRNOP00000030925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,988,250 - 19,043,381 (+)Ensembl
Rnor_6.0 Ensembl1620,740,826 - 20,794,039 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096484   ⟹   ENSRNOP00000079033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,988,250 - 19,043,381 (+)Ensembl
RefSeq Acc Id: NM_001047115   ⟹   NP_001040580
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,210 - 19,080,880 (+)NCBI
mRatBN7.21618,988,239 - 19,046,914 (+)NCBI
Rnor_6.01620,740,826 - 20,794,039 (+)NCBI
Rnor_5.01620,593,102 - 20,649,007 (+)NCBI
RGSC_v3.41619,494,580 - 19,536,787 (+)ENTREZGENE
Celera1619,179,611 - 19,233,207 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006252936   ⟹   XP_006252998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,080,876 (+)NCBI
mRatBN7.21618,988,197 - 19,046,913 (+)NCBI
Rnor_6.01620,740,746 - 20,798,145 (+)NCBI
Rnor_5.01620,593,102 - 20,649,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063275726   ⟹   XP_063131796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,075,143 (+)NCBI
RefSeq Acc Id: XM_063275727   ⟹   XP_063131797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,055,499 - 19,080,876 (+)NCBI
RefSeq Acc Id: XM_063275729   ⟹   XP_063131799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,069,611 (+)NCBI
RefSeq Acc Id: XR_010058319
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,074,603 (+)NCBI
RefSeq Acc Id: XR_010058320
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,075,027 (+)NCBI
RefSeq Acc Id: XR_010058321
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,022,171 - 19,074,603 (+)NCBI
RefSeq Acc Id: NP_001040580   ⟸   NM_001047115
- UniProtKB: Q157S1 (UniProtKB/Swiss-Prot),   A0A8L2QIY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252998   ⟸   XM_006252936
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLX6 (UniProtKB/TrEMBL),   A0A8L2QIY8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030925   ⟸   ENSRNOT00000038057
Ensembl Acc Id: ENSRNOP00000079033   ⟸   ENSRNOT00000096484
RefSeq Acc Id: XP_063131796   ⟸   XM_063275726
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063131799   ⟸   XM_063275729
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131797   ⟸   XM_063275727
- Peptide Label: isoform X3
Protein Domains
Transducer of regulated CREB activity C-terminal   Transducer of regulated CREB activity middle   Transducer of regulated CREB activity N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q157S1-F1-model_v2 AlphaFold Q157S1 1-630 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700033
Promoter ID:EPDNEW_R10556
Type:multiple initiation site
Name:Crtc1_1
Description:CREB regulated transcription coactivator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,740,812 - 20,740,872EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589158 AgrOrtholog
BioCyc Gene G2FUF-11779 BioCyc
Ensembl Genes ENSRNOG00000022421 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038057.6 UniProtKB/TrEMBL
  ENSRNOT00000096484.1 UniProtKB/TrEMBL
InterPro TORC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TORC_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TORC_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TORC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:684527 UniProtKB/Swiss-Prot
NCBI Gene 684527 ENTREZGENE
PANTHER CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13589 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TORC_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TORC_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TORC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Crtc1 PhenoGen
RatGTEx ENSRNOG00000022421 RatGTEx
UniProt A0A8I5ZLX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QIY8 ENTREZGENE, UniProtKB/TrEMBL
  CRTC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-07 Crtc1  CREB regulated transcription coactivator 1  Mect1  mucoepidermoid carcinoma translocated 1  Data merged from RGD:1309794 737654 APPROVED
2008-04-30 Mect1  mucoepidermoid carcinoma translocated 1   Mect1_predicted  mucoepidermoid carcinoma translocated 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 Crtc1  CREB regulated transcription coactivator 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Mect1_predicted  mucoepidermoid carcinoma translocated 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED