Ubr3 (ubiquitin protein ligase E3 component n-recognin 3) - Rat Genome Database

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Gene: Ubr3 (ubiquitin protein ligase E3 component n-recognin 3) Rattus norvegicus
Analyze
Symbol: Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
RGD ID: 1565257
Description: Predicted to enable ubiquitin protein ligase activity. Involved in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel and positive regulation of protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human UBR3 (ubiquitin protein ligase E3 component n-recognin 3); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase UBR3; hypothetical protein LOC311115; LOC311115; RGD1565257; similar to zinc finger protein 650
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,057,615 - 75,214,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl375,057,615 - 75,214,568 (+)EnsemblGRCr8
mRatBN7.2354,649,803 - 54,806,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl354,649,992 - 54,806,247 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx358,051,353 - 58,209,059 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0366,634,951 - 66,792,643 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0364,397,333 - 64,555,042 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,125,927 - 56,283,908 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,125,924 - 56,281,055 (+)Ensemblrn6Rnor6.0
Rnor_5.0362,759,246 - 62,916,651 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4352,034,539 - 52,191,936 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera354,209,320 - 54,366,038 (+)NCBICelera
Cytogenetic Map3q21-q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Modulation of Ca2+-induced Ca2+ release by ubiquitin protein ligase E3 component n-recognin UBR3 and 6 in cardiac myocytes. Ma XE, etal., Channels (Austin). 2020 Dec;14(1):326-335. doi: 10.1080/19336950.2020.1824957.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:17462990   PMID:26059563  


Genomics

Comparative Map Data
Ubr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,057,615 - 75,214,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl375,057,615 - 75,214,568 (+)EnsemblGRCr8
mRatBN7.2354,649,803 - 54,806,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl354,649,992 - 54,806,247 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx358,051,353 - 58,209,059 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0366,634,951 - 66,792,643 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0364,397,333 - 64,555,042 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,125,927 - 56,283,908 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,125,924 - 56,281,055 (+)Ensemblrn6Rnor6.0
Rnor_5.0362,759,246 - 62,916,651 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4352,034,539 - 52,191,936 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera354,209,320 - 54,366,038 (+)NCBICelera
Cytogenetic Map3q21-q22NCBI
UBR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382169,827,454 - 170,084,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2169,827,442 - 170,084,131 (+)Ensemblhg38GRCh38
GRCh372170,683,964 - 170,940,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362170,514,548 - 170,648,883 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342170,631,808 - 170,766,144NCBI
Celera2164,300,400 - 164,556,964 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2162,572,017 - 162,828,315 (+)NCBIHuRef
CHM1_12170,689,889 - 170,947,009 (+)NCBICHM1_1
T2T-CHM13v2.02170,305,020 - 170,561,615 (+)NCBIT2T-CHM13v2.0
Ubr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39269,727,276 - 69,854,354 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl269,727,590 - 69,854,357 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38269,896,932 - 70,024,010 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl269,897,246 - 70,024,013 (+)Ensemblmm10GRCm38
MGSCv37269,735,303 - 69,862,070 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36269,771,018 - 69,825,433 (+)NCBIMGSCv36mm8
Celera271,566,709 - 71,692,184 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map240.95NCBI
Ubr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554494,585,494 - 4,773,413 (-)Ensembl
ChiLan1.0NW_0049554494,583,114 - 4,773,474 (-)NCBIChiLan1.0ChiLan1.0
UBR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21372,488,392 - 72,756,599 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B72,503,370 - 72,770,358 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B57,099,882 - 57,366,981 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B174,564,607 - 174,827,776 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B174,564,671 - 174,827,776 (+)EnsemblpanPan2panpan1.1
UBR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13614,537,900 - 14,723,942 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3614,537,921 - 14,721,790 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3614,510,717 - 14,734,913 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03614,617,883 - 14,845,639 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3614,617,571 - 14,844,702 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13614,700,805 - 14,925,261 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03614,693,007 - 14,919,031 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03614,804,822 - 15,030,558 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303131,771,374 - 131,983,529 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936509324,953 - 535,141 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936509325,277 - 537,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1576,135,494 - 76,360,823 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11576,135,456 - 76,360,819 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21585,315,347 - 85,541,476 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11055,354,367 - 55,616,810 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1055,354,365 - 55,614,520 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040143,913,482 - 144,182,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247877,358,441 - 7,608,483 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247877,358,426 - 7,610,872 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubr3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1547,185,690 - 47,331,769 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubr3
1200 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1176
Count of miRNA genes:286
Interacting mature miRNAs:359
Transcripts:ENSRNOT00000011380, ENSRNOT00000012059, ENSRNOT00000072395
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)37359251285062403Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
D3Chm64  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2354,740,735 - 54,740,965 (+)MAPPERmRatBN7.2
Rnor_6.0356,217,734 - 56,217,961NCBIRnor6.0
Rnor_5.0362,850,379 - 62,850,606UniSTSRnor5.0
RGSC_v3.4352,127,226 - 52,127,454RGDRGSC3.4
RGSC_v3.4352,127,227 - 52,127,454UniSTSRGSC3.4
Celera354,300,329 - 54,300,560UniSTS
Cytogenetic Map3q21UniSTS
D3Chm26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2354,739,476 - 54,739,641 (+)MAPPERmRatBN7.2
Rnor_6.0356,216,475 - 56,216,639NCBIRnor6.0
Rnor_5.0362,849,120 - 62,849,284UniSTSRnor5.0
RGSC_v3.4352,125,967 - 52,126,132RGDRGSC3.4
RGSC_v3.4352,125,968 - 52,126,132UniSTSRGSC3.4
Celera354,299,070 - 54,299,234UniSTS
Cytogenetic Map3q21UniSTS
BE120211  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8375,212,393 - 75,212,563 (+)Marker Load Pipeline
mRatBN7.2354,804,591 - 54,804,761 (+)MAPPERmRatBN7.2
Rnor_6.0356,281,721 - 56,281,890NCBIRnor6.0
Rnor_5.0362,914,464 - 62,914,633UniSTSRnor5.0
RGSC_v3.4352,191,711 - 52,191,880UniSTSRGSC3.4
Celera354,363,851 - 54,364,020UniSTS
RH 3.4 Map4661.37UniSTS
Cytogenetic Map3q21UniSTS
RH138085  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2354,724,975 - 54,725,140 (+)MAPPERmRatBN7.2
Rnor_6.0356,200,657 - 56,200,821NCBIRnor6.0
Rnor_5.0362,834,957 - 62,835,121UniSTSRnor5.0
RGSC_v3.4352,110,866 - 52,111,030UniSTSRGSC3.4
Celera354,284,569 - 54,284,733UniSTS
RH 3.4 Map3603.43UniSTS
Cytogenetic Map3q21UniSTS
MARC_11813-11814:1029266043:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8375,211,254 - 75,211,713 (+)Marker Load Pipeline
mRatBN7.2354,803,452 - 54,803,911 (+)MAPPERmRatBN7.2
Rnor_6.0356,280,582 - 56,281,040NCBIRnor6.0
Rnor_5.0362,913,325 - 62,913,783UniSTSRnor5.0
RGSC_v3.4352,190,572 - 52,191,030UniSTSRGSC3.4
Celera354,362,712 - 54,363,170UniSTS
Cytogenetic Map3q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA503549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011380   ⟹   ENSRNOP00000011380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl375,057,615 - 75,214,568 (+)Ensembl
mRatBN7.2 Ensembl354,649,992 - 54,806,247 (+)Ensembl
Rnor_6.0 Ensembl356,125,924 - 56,281,055 (+)Ensembl
RefSeq Acc Id: NM_001134550   ⟹   NP_001128022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,581 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XM_039104847   ⟹   XP_038960775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,053 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XM_039104848   ⟹   XP_038960776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,053 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XM_039104849   ⟹   XP_038960777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,053 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XM_039104850   ⟹   XP_038960778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,053 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XM_039104851   ⟹   XP_038960779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,214,053 (+)NCBI
mRatBN7.2354,649,803 - 54,806,779 (+)NCBI
RefSeq Acc Id: XR_005501856
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,183,075 (+)NCBI
mRatBN7.2354,649,803 - 54,775,269 (+)NCBI
RefSeq Acc Id: XR_005501857
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,057,615 - 75,183,074 (+)NCBI
mRatBN7.2354,649,803 - 54,775,269 (+)NCBI
Ensembl Acc Id: ENSRNOP00000011380   ⟸   ENSRNOT00000011380
RefSeq Acc Id: XP_038960775   ⟸   XM_039104847
- Peptide Label: isoform X1
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960777   ⟸   XM_039104849
- Peptide Label: isoform X3
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960778   ⟸   XM_039104850
- Peptide Label: isoform X4
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960776   ⟸   XM_039104848
- Peptide Label: isoform X2
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960779   ⟸   XM_039104851
- Peptide Label: isoform X5
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001128022   ⟸   NM_001134550
- UniProtKB: D4A7F0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A7F0-F1-model_v2 AlphaFold D4A7F0 1-1890 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692130
Promoter ID:EPDNEW_R2650
Type:initiation region
Name:Ubr3_1
Description:ubiquitin protein ligase E3 component n-recognin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0356,125,916 - 56,125,976EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565257 AgrOrtholog
BioCyc Gene G2FUF-49495 BioCyc
Ensembl Genes ENSRNOG00000008616 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011380 ENTREZGENE
  ENSRNOT00000011380.10 UniProtKB/TrEMBL
Gene3D-CATH 2.10.110.30 UniProtKB/TrEMBL
InterPro E3_ligase_UBR-like_C UniProtKB/TrEMBL
  UBR1-like UniProtKB/TrEMBL
  UBR1-like_winged-helix UniProtKB/TrEMBL
  Znf_N-recognin UniProtKB/TrEMBL
NCBI Gene 311115 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR3 UniProtKB/TrEMBL
  PTHR21497 UniProtKB/TrEMBL
Pfam PRT6_C UniProtKB/TrEMBL
  UBR1-like_wing UniProtKB/TrEMBL
  zf-UBR UniProtKB/TrEMBL
PhenoGen Ubr3 PhenoGen
PROSITE ZF_UBR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008616 RatGTEx
SMART ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt D4A7F0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-12 Ubr3  ubiquitin protein ligase E3 component n-recognin 3  RGD1565257  similar to zinc finger protein 650  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565257  similar to zinc finger protein 650   RGD1565257_predicted  similar to zinc finger protein 650 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565257_predicted  similar to zinc finger protein 650 (predicted)  LOC311115  similar to zinc finger protein 650  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC311115  similar to zinc finger protein 650      Symbol and Name status set to provisional 70820 PROVISIONAL