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Gene: Itgb1bp2 (integrin subunit beta 1 binding protein 2) Rattus norvegicus

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Symbol:

Itgb1bp2

Name:

integrin subunit beta 1 binding protein 2

RGD ID:

1565015

Description:

Enables integrin binding activity. Predicted to be involved in centrosome duplication. Predicted to be active in Z disc. Orthologous to human ITGB1BP2 (integrin subunit beta 1 binding protein 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

integrin beta 1 binding protein 2; integrin beta-1-binding protein 2; LOC317258; melusin; RGD1565015; similar to melusin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	70,612,118 - 70,617,158 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	70,612,521 - 70,617,158 (+)	Ensembl				GRCr8
mRatBN7.2	X	66,572,537 - 66,577,174 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,572,537 - 66,577,174 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	68,055,878 - 68,060,519 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,556,287 - 71,560,932 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	69,117,186 - 69,121,831 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	71,342,770 - 71,347,623 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,342,775 - 71,347,619 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	72,193,462 - 72,198,315 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	89,520,700 - 89,525,600 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	66,928,207 - 66,932,844 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dilated cardiomyopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

ADP (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

aristolochic acid A (ISO)

ATP (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

calcium atom (ISO)

calcium(0) (ISO)

CGP 52608 (ISO)

copper atom (EXP)

copper(0) (EXP)

corticosterone (EXP)

D-glucose (ISO)

dexamethasone (ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (EXP)

furan (EXP)

glucose (ISO)

glyphosate (EXP)

indole-3-methanol (EXP)

methyl methanesulfonate (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

perfluorooctanoic acid (EXP)

pioglitazone (ISO)

potassium chromate (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

vinclozolin (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

centrosome duplication (IBA)

Cellular Component

Z disc (IBA,IEA,ISO)

Molecular Function

calcium ion binding (IEA,ISO)

integrin binding (IPI)

metal ion binding (IEA)

protein binding (ISO)

SH3 domain binding (IEA)

zinc ion binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain.	Brancaccio M, etal., J Biol Chem. 1999 Oct 8;274(41):29282-8.
2.	Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload.	Brancaccio M, etal., Nat Med. 2003 Jan;9(1):68-75. Epub 2002 Dec 23.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12965203	PMID:21757757	PMID:23198998	PMID:30904475

Genomics

Comparative Map Data

Itgb1bp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	70,612,118 - 70,617,158 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	70,612,521 - 70,617,158 (+)	Ensembl				GRCr8
mRatBN7.2	X	66,572,537 - 66,577,174 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,572,537 - 66,577,174 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	68,055,878 - 68,060,519 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,556,287 - 71,560,932 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	69,117,186 - 69,121,831 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	71,342,770 - 71,347,623 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,342,775 - 71,347,619 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	72,193,462 - 72,198,315 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	89,520,700 - 89,525,600 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	66,928,207 - 66,932,844 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

ITGB1BP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	71,301,750 - 71,305,371 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	71,301,747 - 71,305,371 (+)	Ensembl			hg38	GRCh38
GRCh37	X	70,521,600 - 70,525,221 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	70,438,353 - 70,441,929 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	70,304,648 - 70,308,225	NCBI
Celera	X	70,875,506 - 70,879,082 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	64,337,919 - 64,341,495 (+)	NCBI		HuRef
CHM1_1	X	70,414,681 - 70,418,257 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	69,735,860 - 69,739,481 (+)	NCBI		T2T-CHM13v2.0

Itgb1bp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	100,492,694 - 100,520,391 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	100,492,694 - 100,497,147 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	101,449,088 - 101,466,122 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	101,449,088 - 101,453,541 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	98,644,448 - 98,648,880 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	97,651,884 - 97,656,498 (+)	NCBI		MGSCv36	mm8
Celera	X	88,366,894 - 88,371,326 (+)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	44.17	NCBI

Itgb1bp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	10,854,270 - 10,858,636 (+)	Ensembl
ChiLan1.0	NW_004955475	10,854,148 - 10,858,802 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITGB1BP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	70,974,360 - 70,978,179 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	70,977,720 - 70,981,782 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	60,564,946 - 60,569,045 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	70,620,027 - 70,624,138 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	70,620,025 - 70,624,138 (+)	Ensembl			panPan2	panpan1.1

ITGB1BP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	55,632,566 - 55,652,801 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	55,633,060 - 55,636,868 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	46,459,421 - 46,479,596 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	56,601,297 - 56,621,805 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	56,601,734 - 56,605,538 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	54,568,927 - 54,589,320 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	55,900,649 - 55,921,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	55,828,059 - 55,848,566 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Itgb1bp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	46,555,881 - 46,560,183 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936762	318,055 - 321,843 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936762	318,055 - 322,358 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITGB1BP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	57,316,471 - 57,325,096 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	57,316,490 - 57,321,614 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ITGB1BP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	61,112,400 - 61,117,566 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	61,113,673 - 61,118,040 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666065	2,963,649 - 2,968,066 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itgb1bp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	1,584,519 - 1,588,617 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624903	1,583,796 - 1,588,778 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Itgb1bp2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	59,093,869 - 59,098,990 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Itgb1bp2
15 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	48
Count of miRNA genes:	43
Interacting mature miRNAs:	47
Transcripts:	ENSRNOT00000004888
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	44930883	89930883	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	159	91	90	59	91	59	6	353	190	11	137	80	91	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM116382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM118664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004888 ⟹ ENSRNOP00000004888

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	70,612,521 - 70,617,158 (+)	Ensembl
mRatBN7.2 Ensembl	X	66,572,537 - 66,577,174 (+)	Ensembl
Rnor_6.0 Ensembl	X	71,342,775 - 71,347,619 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110786 ⟹ ENSRNOP00000087908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	66,572,585 - 66,577,170 (+)	Ensembl

RefSeq Acc Id:

NM_001108245 ⟹ NP_001101715

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,612,521 - 70,617,158 (+)	NCBI
mRatBN7.2	X	66,572,537 - 66,577,174 (+)	NCBI
Rnor_6.0	X	71,342,770 - 71,347,623 (+)	NCBI
Rnor_5.0	X	72,193,462 - 72,198,315 (+)	NCBI
RGSC_v3.4	X	89,520,700 - 89,525,600 (+)	RGD
Celera	X	66,928,207 - 66,932,844 (+)	NCBI

Sequence:

show sequence

CCCACACTGCAGCCAGACTCCTTGAAATACCCTTTGAGTAAGCTCGGTCAGTGCCTCCATGTCT
CTGCTCTGCTATAACAAAGGCTGTGGGCAACACTTTGACCCCAATACCAATCTCCCTGATTCCT
GCCGTTATCACCCTGGGGTCCCAATCTTTCATGATGCACTTAAGGGTTGGTCCTGCTGCCGAAA
GCGAACTGTAGATTTCTCTGAGTTCTTAAACATCAAGGGCTGTACTGTGGGACCACACTGTGCT
GAGAAGCTTCCTGAGGTCCCTCAGCCTGAGGGCCCTGCCACAAGTTCACTTCAGGAGCAAAAAC
CTCTGAATACAATTCCAAAGTCAGCAGAGACTTTGCTCCGAGAAAGGCCTAAGTCTGAGATGCC
TCCGAAACTGCTACCACTTCTTATATCTCAAGCCCTGGGAGTGGCGTTGGAACAGAAAGAATTA
GACCAGGAACCTGGAGCAGGACTTGACAATAGTCTGATCTGGACTGGTTCCAGCTGCCAGAACC
CAGGATGTGATGCTGTTTACCAAGGTCCTGAGAGTGATGCTACTCCGTGTACCTATCATCCAGG
TGCACCTCGGTTTCATGAGGGAATGAAGTCTTGGAGCTGTTGTGGTATCCAGACTCTGGATTTT
GGGGCATTCCTGGCACAGCCAGGATGTAGAGTTGGTAGACACGATTGGGCAAAGCAGCTGCCAG
CATCTTGCCGCCATGATTGGCACCAGACAGATTCTTTGGTAGTGCTCACGGTCTATGGCCAGAT
TCCACTTCCTGCATTCAACTGGGTGAAGGCCAGTCAAACTGAGCTTCATGTCCACATTGTCTTT
GATGGTAACCGTGTGTTCCAAGCACAGATGAAGCTCTGGGGGGTCATAAACGTGGAGCAGAGCT
CTGTCTCTTTGATGCCATCACGGGTTGAAATCTCCCTGGTCAAGGCTGACCCAGGATCCTGGGC
CCAGCTGGAGCACCCCGATTCACTAGCTGAGAAGGCTAGGGCAGGGGTTTTACTAGAGATGGAT
GAGGAAGAATCTGAGGATTCAGATGATGACCTGAGCTGGACAGAAGAGGAAGATGAAGACGAGG
AAGAAGCTATGGGGGAATAGGAACAGCAGACAGTTGAGTTTCTAGGCAGGCCCTCAGTGACTGC
CTTAGAATCTCAGAGACCAGGATAGGGTTGACTATGTGGTGTCATTGAGCAGCAGGAGGCTGAA
GGAAGAGATAACAAAATGTCCAAACTGCTGCTGCCCCCTAATAAACCTTACATTCTGCAGTCTC
ACCCA

hide sequence

RefSeq Acc Id:

XM_063280031 ⟹ XP_063136101

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,612,118 - 70,617,154 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101715	(Get FASTA)	NCBI Sequence Viewer
	XP_063136101	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL95891	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004888
	ENSRNOP00000004888.4

RefSeq Acc Id:

NP_001101715 ⟸ NM_001108245

- UniProtKB:

D3ZW59 (UniProtKB/TrEMBL), A6IQC2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLLCYNKGCGQHFDPNTNLPDSCRYHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTVGPH
CAEKLPEVPQPEGPATSSLQEQKPLNTIPKSAETLLRERPKSEMPPKLLPLLISQALGVALEQK
ELDQEPGAGLDNSLIWTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTL
DFGAFLAQPGCRVGRHDWAKQLPASCRHDWHQTDSLVVLTVYGQIPLPAFNWVKASQTELHVHI
VFDGNRVFQAQMKLWGVINVEQSSVSLMPSRVEISLVKADPGSWAQLEHPDSLAEKARAGVLLE
MDEEESEDSDDDLSWTEEEDEDEEEAMGE

hide sequence

Ensembl Acc Id:

ENSRNOP00000004888 ⟸ ENSRNOT00000004888

Ensembl Acc Id:

ENSRNOP00000087908 ⟸ ENSRNOT00000110786

RefSeq Acc Id:	XP_063136101 ⟸ XM_063280031
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A523 (UniProtKB/TrEMBL)

Protein Domains

CHORD CS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZW59-F1-model_v2	AlphaFold	D3ZW59	1-349	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701878

Promoter ID:

EPDNEW_R12402

Type:

single initiation site

Name:

Itgb1bp2_1

Description:

integrin subunit beta 1 binding protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	71,342,773 - 71,342,833	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565015	AgrOrtholog
BioCyc Gene	G2FUF-2098	BioCyc
Ensembl Genes	ENSRNOG00000003596	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004888	ENTREZGENE
	ENSRNOT00000004888.9	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.790	UniProtKB/TrEMBL
	4.10.1130.20	UniProtKB/TrEMBL
InterPro	CHORD	UniProtKB/TrEMBL
	CHRD1	UniProtKB/TrEMBL
	CS-like_domain	UniProtKB/TrEMBL
	HSP20-like_chaperone	UniProtKB/TrEMBL
KEGG Report	rno:317258	UniProtKB/TrEMBL
NCBI Gene	317258	ENTREZGENE
PANTHER	CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	ZGC:92429	UniProtKB/TrEMBL
Pfam	CHORD	UniProtKB/TrEMBL
	PF04969	UniProtKB/TrEMBL
PhenoGen	Itgb1bp2	PhenoGen
PROSITE	CHORD	UniProtKB/TrEMBL
	PS51203	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003596	RatGTEx
Superfamily-SCOP	HSP20_chap	UniProtKB/TrEMBL
UniProt	A0A8I6A523	ENTREZGENE
	A6IQC2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZW59	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-23	Itgb1bp2	integrin subunit beta 1 binding protein 2	Itgb1bp2	integrin beta 1 binding protein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Itgb1bp2	integrin beta 1 binding protein 2	Itgb1bp2_predicted	integrin beta 1 binding protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Itgb1bp2_predicted	integrin beta 1 binding protein 2 (predicted)	RGD1565015_predicted	similar to melusin (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1565015_predicted	similar to melusin (predicted)	LOC317258	similar to melusin	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC317258	similar to melusin			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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