Supt5h (SPT5 homolog, DSIF elongation factor subunit) - Rat Genome Database

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Gene: Supt5h (SPT5 homolog, DSIF elongation factor subunit) Rattus norvegicus
Analyze
Symbol: Supt5h
Name: SPT5 homolog, DSIF elongation factor subunit
RGD ID: 1563807
Description: Predicted to enable several functions, including chromatin binding activity; mRNA binding activity; and protein heterodimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of DSIF complex. Orthologous to human SUPT5H (SPT5 homolog, DSIF elongation factor subunit); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: suppressor of Ty 5 homolog; suppressor of Ty 5 homolog (S. cerevisiae); transcription elongation factor SPT5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,714,276 - 92,745,489 (-)NCBIGRCr8
mRatBN7.2183,586,713 - 83,616,971 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,998,987 - 89,028,238 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0197,457,333 - 97,486,505 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,754,847 - 90,784,099 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0185,437,780 - 85,466,854 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,437,780 - 85,466,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,651,790 - 86,680,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,433,056 - 83,434,029 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera177,985,530 - 78,013,882 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
DSIF complex  (IBA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens. Asakura K, etal., J Neuroimmunol 1996 Mar;65(1):11-9.
2. Transcription elongation factors are involved in programming hormone production in pituitary neuroendocrine GH4C1 cells. Fujita T, etal., Mol Cell Endocrinol. 2010 May 5;319(1-2):63-70. doi: 10.1016/j.mce.2010.01.020. Epub 2010 Jan 25.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation. Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
Additional References at PubMed
PMID:9450929   PMID:10075709   PMID:11596118   PMID:12477932   PMID:16778019   PMID:19575011   PMID:21670248   PMID:22354037   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Supt5h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,714,276 - 92,745,489 (-)NCBIGRCr8
mRatBN7.2183,586,713 - 83,616,971 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,998,987 - 89,028,238 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0197,457,333 - 97,486,505 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,754,847 - 90,784,099 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0185,437,780 - 85,466,854 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,437,780 - 85,466,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,651,790 - 86,680,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,433,056 - 83,434,029 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera177,985,530 - 78,013,882 (-)NCBICelera
Cytogenetic Map1q21NCBI
SUPT5H
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381939,445,582 - 39,476,670 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1939,436,156 - 39,476,670 (+)EnsemblGRCh38hg38GRCh38
GRCh371939,936,222 - 39,967,310 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361944,628,164 - 44,659,150 (+)NCBINCBI36Build 36hg18NCBI36
Build 341944,628,163 - 44,659,146NCBI
Celera1936,737,890 - 36,769,015 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1936,382,774 - 36,413,888 (+)NCBIHuRef
CHM1_11939,936,824 - 39,967,943 (+)NCBICHM1_1
T2T-CHM13v2.01942,249,844 - 42,280,929 (+)NCBIT2T-CHM13v2.0
Supt5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,014,316 - 28,038,341 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,014,316 - 28,038,171 (-)EnsemblGRCm39 Ensembl
GRCm38728,314,891 - 28,338,804 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl728,314,891 - 28,338,746 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,099,913 - 29,123,738 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,023,654 - 28,047,479 (-)NCBIMGSCv36mm8
Celera722,876,535 - 22,900,354 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map716.68NCBI
Supt5h
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546895,181 - 123,147 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546895,997 - 123,005 (-)NCBIChiLan1.0ChiLan1.0
SUPT5H
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22045,739,186 - 45,772,352 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11947,611,755 - 47,642,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01936,543,998 - 36,575,161 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11945,092,075 - 45,122,335 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1945,092,075 - 45,122,335 (+)Ensemblpanpan1.1panPan2
SUPT5H
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,759,419 - 113,788,490 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,759,423 - 113,788,447 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1113,163,184 - 113,192,230 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01114,360,336 - 114,389,453 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1114,336,273 - 114,389,434 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,919,385 - 113,948,409 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01113,552,396 - 113,581,431 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01114,546,802 - 114,576,065 (-)NCBIUU_Cfam_GSD_1.0
Supt5h
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934913,852,258 - 13,880,016 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,280,285 - 2,308,780 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,280,390 - 2,308,085 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUPT5H
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,095,041 - 48,125,120 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,095,001 - 48,125,120 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2643,834,849 - 43,864,980 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUPT5H
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1634,052,587 - 34,086,022 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl634,052,577 - 34,085,782 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607312,073,636 - 12,107,025 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Supt5h
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479412,766,806 - 12,804,611 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479412,766,734 - 12,791,590 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Supt5h
184 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:91
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000048905, ENSRNOT00000057470
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
RH124224  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2183,590,293 - 83,590,488 (-)MAPPERmRatBN7.2
Rnor_6.0185,463,079 - 85,463,273NCBIRnor6.0
Rnor_5.0186,676,682 - 86,676,876UniSTSRnor5.0
RGSC_v3.4183,408,363 - 83,408,557UniSTSRGSC3.4
Celera177,989,111 - 77,989,305UniSTS
Cytogenetic Map1q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 141 227 147 69 147 36 45 250 115 145 57 24
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB751273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR755056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ764483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY319730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L41685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000048905   ⟹   ENSRNOP00000049521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)Ensembl
Rnor_6.0 Ensembl185,438,105 - 85,466,635 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)Ensembl
Rnor_6.0 Ensembl185,460,888 - 85,466,854 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)Ensembl
Rnor_6.0 Ensembl185,437,816 - 85,460,238 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093384   ⟹   ENSRNOP00000076183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)Ensembl
Rnor_6.0 Ensembl185,460,888 - 85,466,854 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093740   ⟹   ENSRNOP00000076244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl183,586,718 - 83,616,892 (-)Ensembl
Rnor_6.0 Ensembl185,437,780 - 85,460,238 (+)Ensembl
RefSeq Acc Id: NM_001107497   ⟹   NP_001100967
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,445 (-)NCBI
mRatBN7.2183,586,713 - 83,616,892 (-)NCBI
Rnor_6.0185,437,780 - 85,466,854 (+)NCBI
Rnor_5.0186,651,790 - 86,680,457 (+)NCBI
RGSC_v3.4183,433,056 - 83,434,029 (-)RGD
Celera177,985,530 - 78,013,882 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111567   ⟹   XP_038967495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,444 (-)NCBI
mRatBN7.2183,586,932 - 83,616,960 (-)NCBI
RefSeq Acc Id: XM_039111569   ⟹   XP_038967497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,745,489 (-)NCBI
mRatBN7.2183,586,932 - 83,616,971 (-)NCBI
RefSeq Acc Id: XM_039111570   ⟹   XP_038967498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,509 (-)NCBI
mRatBN7.2183,586,713 - 83,616,971 (-)NCBI
RefSeq Acc Id: XM_063261507   ⟹   XP_063117577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,388 (-)NCBI
RefSeq Acc Id: XM_063261515   ⟹   XP_063117585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,427 (-)NCBI
RefSeq Acc Id: XM_063261518   ⟹   XP_063117588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,444 (-)NCBI
RefSeq Acc Id: XM_063261526   ⟹   XP_063117596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,745,489 (-)NCBI
RefSeq Acc Id: XM_063261528   ⟹   XP_063117598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,714,276 - 92,744,147 (-)NCBI
RefSeq Acc Id: NP_001100967   ⟸   NM_001107497
- UniProtKB: A0A8I5ZQE4 (UniProtKB/TrEMBL),   E9PTB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076244   ⟸   ENSRNOT00000093740
Ensembl Acc Id: ENSRNOP00000076183   ⟸   ENSRNOT00000093384
Ensembl Acc Id: ENSRNOP00000049521   ⟸   ENSRNOT00000048905
RefSeq Acc Id: XP_038967498   ⟸   XM_039111570
- Peptide Label: isoform X3
- UniProtKB: A0A1W2Q6F0 (UniProtKB/TrEMBL),   E9PTB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967497   ⟸   XM_039111569
- Peptide Label: isoform X2
- UniProtKB: A0A1W2Q689 (UniProtKB/TrEMBL),   E9PTB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967495   ⟸   XM_039111567
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZQE4 (UniProtKB/TrEMBL),   E9PTB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117596   ⟸   XM_063261526
- Peptide Label: isoform X4
- UniProtKB: E9PTB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117588   ⟸   XM_063261518
- Peptide Label: isoform X2
- UniProtKB: E9PTB2 (UniProtKB/TrEMBL),   A0A1W2Q689 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117585   ⟸   XM_063261515
- Peptide Label: isoform X2
- UniProtKB: E9PTB2 (UniProtKB/TrEMBL),   A0A1W2Q689 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117577   ⟸   XM_063261507
- Peptide Label: isoform X1
- UniProtKB: E9PTB2 (UniProtKB/TrEMBL),   A0A8I5ZQE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117598   ⟸   XM_063261528
- Peptide Label: isoform X5
- UniProtKB: E9PTB2 (UniProtKB/TrEMBL),   A6J9H9 (UniProtKB/TrEMBL)
Protein Domains
KOW   NusG-like N-terminal   Spt5 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PTB2-F1-model_v2 AlphaFold E9PTB2 1-1083 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689878
Promoter ID:EPDNEW_R399
Type:initiation region
Name:Supt5h_1
Description:SPT5 homolog, DSIF elongation factor subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0185,437,802 - 85,437,862EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563807 AgrOrtholog
BioCyc Gene G2FUF-60255 BioCyc
Ensembl Genes ENSRNOG00000032034 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048905.7 UniProtKB/TrEMBL
  ENSRNOT00000093345.2 UniProtKB/TrEMBL
  ENSRNOT00000093383.2 UniProtKB/TrEMBL
  ENSRNOT00000093384.2 UniProtKB/TrEMBL
  ENSRNOT00000093740.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.30 UniProtKB/TrEMBL
  3.30.70.940 UniProtKB/TrEMBL
InterPro KOW UniProtKB/TrEMBL
  KOW_Spt5_1 UniProtKB/TrEMBL
  KOW_Spt5_2 UniProtKB/TrEMBL
  KOW_Spt5_3 UniProtKB/TrEMBL
  KOW_Spt5_4 UniProtKB/TrEMBL
  KOW_Spt5_5 UniProtKB/TrEMBL
  KOW_Spt5_6 UniProtKB/TrEMBL
  NGN_dom_sf UniProtKB/TrEMBL
  NGN_Euk UniProtKB/TrEMBL
  Rib_L2_dom2 UniProtKB/TrEMBL
  SPT5 UniProtKB/TrEMBL
  Spt5_C_dom UniProtKB/TrEMBL
  Spt5_N UniProtKB/TrEMBL
  TF_Spt5 UniProtKB/TrEMBL
  TF_Spt5_NGN-domain UniProtKB/TrEMBL
  Transcrpt_antiterm_NusG_N UniProtKB/TrEMBL
  Translation_prot_SH3-like UniProtKB/TrEMBL
KEGG Report rno:308472 UniProtKB/TrEMBL
NCBI Gene 308472 ENTREZGENE
PANTHER PTHR11125 UniProtKB/TrEMBL
  TRANSCRIPTION ELONGATION FACTOR SPT5 UniProtKB/TrEMBL
Pfam KOW UniProtKB/TrEMBL
  Spt5-NGN UniProtKB/TrEMBL
  Spt5_N UniProtKB/TrEMBL
PhenoGen Supt5h PhenoGen
PIRSF Spt5 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032034 RatGTEx
SMART CTD UniProtKB/TrEMBL
  KOW UniProtKB/TrEMBL
  NGN UniProtKB/TrEMBL
Superfamily-SCOP Transl_SH3_like UniProtKB/TrEMBL
UniProt A0A1W2Q689 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2Q6F0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZR84_RAT UniProtKB/TrEMBL
  A6J9H9 ENTREZGENE, UniProtKB/TrEMBL
  A6J9I0_RAT UniProtKB/TrEMBL
  A6J9I2_RAT UniProtKB/TrEMBL
  E9PTB2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-07 Supt5h  SPT5 homolog, DSIF elongation factor subunit  Supt5h  suppressor of Ty 5 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Supt5h  suppressor of Ty 5 homolog (S. cerevisiae)      Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 Supt5h  suppressor of Ty 5 homolog (S. cerevisiae)      Symbol and Name status set to provisional 70820 PROVISIONAL