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Gene: Supt5h (SPT5 homolog, DSIF elongation factor subunit) Rattus norvegicus

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Symbol:

Supt5h

Name:

SPT5 homolog, DSIF elongation factor subunit

RGD ID:

1563807

Description:

Predicted to enable several functions, including chromatin binding activity; enzyme binding activity; and protein heterodimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of DSIF complex. Orthologous to human SUPT5H (SPT5 homolog, DSIF elongation factor subunit); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

suppressor of Ty 5 homolog; suppressor of Ty 5 homolog (S. cerevisiae); transcription elongation factor SPT5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Supt5 (suppressor of Ty 5, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Supt5h (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Supt5h (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Supt5h (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Supt5h (SPT5 homolog, DSIF elongation factor subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PYY (peptide YY)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SUPT5H (SPT5 homolog, DSIF elongation factor subunit)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Supt5 (suppressor of Ty 5, DSIF elongation factor subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	supt5h (SPT5 homolog, DSIF elongation factor subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Spt5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SPT5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	spt-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	spt-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	supt5h	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	supt5h	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	92,714,276 - 92,745,489 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl				GRCr8
mRatBN7.2	1	83,586,713 - 83,616,971 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	88,998,987 - 89,028,238 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	97,457,333 - 97,486,505 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	90,754,847 - 90,784,099 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	85,437,780 - 85,466,854 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	85,437,780 - 85,466,854 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	86,651,790 - 86,680,457 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	83,433,056 - 83,434,029 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	77,985,530 - 78,013,882 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

alvocidib (ISO)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

clofibrate (ISO)

clofibric acid (EXP)

cocaine (EXP)

coumarin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dimethyl sulfoxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

FR900359 (ISO)

gallic acid (ISO)

geraniol (ISO)

ivermectin (ISO)

methamphetamine (ISO)

methimazole (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

nitrates (ISO)

Nutlin-3 (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

selenium atom (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

Triptolide (ISO)

triptonide (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

DNA-templated transcription elongation (IEA)

negative regulation of DNA-templated transcription, elongation (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of DNA-templated transcription, elongation (IEA,ISO)

positive regulation of macroautophagy (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,IMP,ISO)

positive regulation of transcription elongation by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription elongation (IEA)

regulation of transcription by RNA polymerase II (IEA)

regulation of transcription elongation by RNA polymerase II (IEA,ISO)

transcription elongation by RNA polymerase II (IEA,ISO)

transcription pausing by RNA polymerase II (IEA,ISO)

Cellular Component

DSIF complex (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

Molecular Function

enzyme binding (IEA,ISO)

protein binding (ISO)

protein heterodimerization activity (IEA,ISO)

RNA polymerase inhibitor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase I transcription pathway (ISO)

RNA polymerase II transcription elongation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens.	Asakura K, etal., J Neuroimmunol 1996 Mar;65(1):11-9.
2.	Transcription elongation factors are involved in programming hormone production in pituitary neuroendocrine GH4C1 cells.	Fujita T, etal., Mol Cell Endocrinol. 2010 May 5;319(1-2):63-70. doi: 10.1016/j.mce.2010.01.020. Epub 2010 Jan 25.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Control of transcriptional elongation.	Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.	Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.

Additional References at PubMed

PMID:9450929	PMID:10075709	PMID:11596118	PMID:12477932	PMID:16778019	PMID:19575011	PMID:21670248	PMID:22354037	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Supt5h
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	92,714,276 - 92,745,489 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl				GRCr8
mRatBN7.2	1	83,586,713 - 83,616,971 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	88,998,987 - 89,028,238 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	97,457,333 - 97,486,505 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	90,754,847 - 90,784,099 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	85,437,780 - 85,466,854 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	85,437,780 - 85,466,854 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	86,651,790 - 86,680,457 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	83,433,056 - 83,434,029 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	77,985,530 - 78,013,882 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

SUPT5H
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	39,445,582 - 39,476,670 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	39,436,156 - 39,476,670 (+)	Ensembl			hg38	GRCh38
GRCh37	19	39,936,222 - 39,967,310 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	44,628,164 - 44,659,150 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	44,628,163 - 44,659,146	NCBI
Celera	19	36,737,890 - 36,769,015 (+)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	36,382,774 - 36,413,888 (+)	NCBI		HuRef
CHM1_1	19	39,936,824 - 39,967,943 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	42,249,844 - 42,280,929 (+)	NCBI		T2T-CHM13v2.0

Supt5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	28,014,316 - 28,038,341 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	28,014,316 - 28,038,171 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	28,314,891 - 28,338,804 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	28,314,891 - 28,338,746 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	29,099,913 - 29,123,738 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	28,023,654 - 28,047,479 (-)	NCBI		MGSCv36	mm8
Celera	7	22,876,535 - 22,900,354 (-)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	16.68	NCBI

Supt5h
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	95,181 - 123,147 (-)	Ensembl
ChiLan1.0	NW_004955468	95,997 - 123,005 (-)	NCBI	ChiLan1.0	ChiLan1.0

SUPT5H
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	45,739,186 - 45,772,352 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	47,611,755 - 47,642,916 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	36,543,998 - 36,575,161 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	45,092,075 - 45,122,335 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	45,092,075 - 45,122,335 (+)	Ensembl			panPan2	panpan1.1

SUPT5H
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	113,759,419 - 113,788,490 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	113,759,423 - 113,788,447 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,163,184 - 113,192,230 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,360,336 - 114,389,453 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,336,273 - 114,389,434 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	113,919,385 - 113,948,409 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	113,552,396 - 113,581,431 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	114,546,802 - 114,576,065 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Supt5h
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	13,852,258 - 13,880,016 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	2,280,285 - 2,308,780 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	2,280,390 - 2,308,085 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUPT5H
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	48,095,041 - 48,125,119 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	48,095,001 - 48,125,120 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,834,849 - 43,864,980 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SUPT5H
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	34,052,587 - 34,086,022 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	34,052,577 - 34,085,782 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	12,073,636 - 12,107,025 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Supt5h
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	12,766,806 - 12,804,611 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624794	12,766,734 - 12,791,590 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Supt5h
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	167,669,750 - 167,697,705 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Supt5h
145 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	158
Count of miRNA genes:	91
Interacting mature miRNAs:	95
Transcripts:	ENSRNOT00000048905, ENSRNOT00000057470
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat

Markers in Region

RH124224

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	83,590,293 - 83,590,488 (-)	MAPPER	mRatBN7.2
Rnor_6.0	1	85,463,079 - 85,463,273	NCBI	Rnor6.0
Rnor_5.0	1	86,676,682 - 86,676,876	UniSTS	Rnor5.0
RGSC_v3.4	1	83,408,363 - 83,408,557	UniSTS	RGSC3.4
Celera	1	77,989,111 - 77,989,305	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB751273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR755056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ764483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY319730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L41685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000048905 ⟹ ENSRNOP00000049521

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl
Rnor_6.0 Ensembl	1	85,438,105 - 85,466,635 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093345

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl
Rnor_6.0 Ensembl	1	85,460,888 - 85,466,854 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093383

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl
Rnor_6.0 Ensembl	1	85,437,816 - 85,460,238 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093384 ⟹ ENSRNOP00000076183

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl
Rnor_6.0 Ensembl	1	85,460,888 - 85,466,854 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093740 ⟹ ENSRNOP00000076244

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	92,714,281 - 92,744,445 (-)	Ensembl
mRatBN7.2 Ensembl	1	83,586,718 - 83,616,892 (-)	Ensembl
Rnor_6.0 Ensembl	1	85,437,780 - 85,460,238 (+)	Ensembl

RefSeq Acc Id:

NM_001107497 ⟹ NP_001100967

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,445 (-)	NCBI
mRatBN7.2	1	83,586,713 - 83,616,892 (-)	NCBI
Rnor_6.0	1	85,437,780 - 85,466,854 (+)	NCBI
Rnor_5.0	1	86,651,790 - 86,680,457 (+)	NCBI
RGSC_v3.4	1	83,433,056 - 83,434,029 (-)	RGD
Celera	1	77,985,530 - 78,013,882 (-)	NCBI

Sequence:

show sequence

CGAGAGAGCGCTCAGGCCAGCTAGGCGTTGTGTGATCAGCAGCTGGCGCGGAAGCTTCAGGTGG
ACAGTGATCGTTGCGGAAGATGTCGGACAGCGAAGACAGCAACTTCTCGGAGGAGGAGGACAGC
GAGCGCAGCAGCGAGGCGGAGGAGGCCGAGGTAGAGGAAGACCGGCGAAGTGCCGCAGGCAGTG
AAAAAGAAGAGGAGCCCGAGGAAGAGGAGGAGGAGGAAGAGGAGGAATACGATGAGGAGGAGGA
GGAGGAGGATGATGACCGGCCTCCCAAGAAACCACGCCATGGGGGCTTCATTTTAGATGAGGCT
GATGTCGATGATGAATATGAAGATGAAGACCAGTGGGAAGATGGAGCTGAAGATATCCTGGAGA
AAGAAGAGATTGAAGCCTCCAACATTGATAACGTTGTGCTGGATGAAGACCGCTCTGGGGCTCG
TCGTCTGCAAAATCTCTGGAGGGACCAGAGAGAAGAAGAACTGGGCGAGTATTACATGAAGAAA
TATGCCAAGTCATCTGTGGGAGAGACGGTATATGGAGGGTCTGATGAGCTCTCAGATGACATCA
CCCAGCAGCAGCTGCTCCCAGGAGTCAAGGACCCCAACCTGTGGACGGTCAAGTGTAAGATTGG
GGAGGAACGGGCCACAGCAATTTCCTTGATGCGAAAATTCATCGCTTACCAGTTCACAGACACA
CCCCTGCAGATTAAGTCAGTGGTTGCCCCGGAGCATGTGAAGGGCTACATCTATGTGGAGGCCT
ACAAACAGACCCATGTGAAGCAGGCCATTGAGGGTGTGGGCAACCTGCGGCTTGGCTACTGGAA
CCAGCAGATGGTGCCTATTAAGGAGATGACCGATGTACTCAAGGTGGTGAAGGAGGTGGCCAAC
CTGAAGCCGAAGTCCTGGGTCCGCCTCAAGAGAGGCATCTACAAAGATGACATCGCTCAGGTGG
ACTACGTCGAGCCCAGCCAGAACACCATTTCCCTGAAGATGATCCCGCGCATTGACTATGACCG
CATCAAAGCCCGCATGAGCTTGAAAGACTGGTTTGCCAAAAGGAAGAAGTTCAAGCGGCCTCCA
CAGAGGCTCTTTGATGCTGAAAAGATCAGGTCCTTGGGGGGTGATGTTGCCTCTGATGGTGACT
TCCTCATCTTTGAGGGTAACCGCTACAGCCGGAAGGGCTTCCTGTTCAAGAGTTTTGCCATGTC
TGCTGTGATTACAGAAGGTGTAAAGCCCACCCTGTCAGAGCTGGAAAAGTTTGAGGATCAGCCT
GAGGGCATCGACTTGGAGGTGGTGACTGAAAGCACAGGGAAGGAGCGAGAGCACAATTTCCAGC
CTGGTGACAATGTGGAGGTGTGTGAGGGTGAGCTCATCAACCTGCAGGGCAAGGTCCTCAGCGT
GGATGGCAACAAGATCACCATCATGCCCAAACATGAGGACCTCAAGGACATGCTTGAGTTCCCA
GCTCAGGAACTTCGGAAGTACTTCAAGATGGGAGACCATGTAAAAGTGATTGCTGGCCGATTTG
AGGGTGACACAGGTCTCATCGTGCGGGTGGAAGAGAACTTTGTTATTCTTTTCTCAGACCTCAC
CATGCACGAGTTGAAAGTGCTTCCCCGGGATCTGCAGCTCTGCTCAGAGACAGCCTCAGGTGTG
GATGTTGGGGGCCAGCATGAGTGGGGTGAGCTGGTGCAGTTGGATCCCCGGACTGTAGGTGTCA
TCGTGCGGCTGGAGCGAGAGACCTTCCAGGTTCTCAACATGCATGGGAAAGTGGTGACTGTAAG
GCACCAGGCTGTGACGCAGAAAAAGGACAACCGCTTCGCTGTGGCTCTGGACTCAGATCAGAAC
AACATCCATGTGAAGGACATTGTTAAGGTCATTGATGGCCCCCATTCAGGCCGAGAGGGTGAGA
TCCGCCATCTGTACCGCAGCTTTGCCTTCCTGCATTGCAAGAAGCTGGTGGAGAATGGCGGCAT
GTTTGTCTGTAAGGCACGGCACCTGGTGTTGGCTGGGGGCTCAAAGCCCCGGGATGTGACCAAT
TTAACTGTTGGTGGCTTCACTCCTATGAGCCCCCGGATCAGCAGCCCTATGCACCCCAGTGCTG
AAGGTCAGCATGGTGGTTTTGGAAGCCCAGGTGGCATGAGCAGGGGTCGAGGGCGAAGAGACAA
TGAGCTCATAGGCCAGACTGTGCGTATCTCCCAGGGACCCTACAAAGGCTACATTGGTGTGGTG
AAGGATGCCACGGAGTCCACAGCCCGAGTAGAATTGCACTCTACCTGCCAGACCATCTCTGTGG
ACCGCCAGCGGCTCACCACAGTTGACTCCCAGCGTCCAGGTGGCATGACTTCCACCTATGGAAG
GACTCCCATGTATGGCTCTCAGACTCCCATGTATGGCTCTGGCTCCCGAACACCCATGTATGGC
TCCCAGACACCTCTGCAGGATGGTAGCCGCACTCCACATTATGGCTCACAGACACCCCTGCATG
ATGGTAGCCGCACTCCTGCTCAGAGTGGGGCCTGGGATCCCAACAACCCTAACACACCTTCCAG
GGCTGAGGAGGAATACGAATATGCCTTTGACGACGAACCCACCCCATCCCCACAAGCATATGGG
GGAACCCCGAATCCCCAAACACCCGGCTACCCAGACCCATCATCCCCCCAGGTCAATCCACAGT
ACAACCCGCAGACACCCGGGACGCCAGCCATGTACAACACAGACCAGTTCTCCCCCTACGCTGC
CCCCTCCCCACAGGGGTCTTACCAGCCCAGCCCCAGCCCCCAGAGCTACCACCAAGTGGCACCA
AGTCCAGCGGGCTATCAGAACACCCATTCCCCAGCCAGCTACCACCCAACACCGTCACCCATGG
CCTATCAGGCTAGTCCCAGCCCCAGCCCTGTTGGCTACAGTCCAATGACCCCTGGAGCTCCTTC
TCCTGGAGGCTACAATCCCCACACACCAGGCTCAGGCATTGAGCAGAACTCCAGTGACTGGGTG
ACCACTGATATCCAGGTGAAGGTTCGAGACACCTATCTGGACACACAAATAGTGGGGCAGACAG
GCGTCATCCGCAGTGTCACGGGAGGCATGTGCTCCGTGTACCTGAAAGATAGTGAGAAGGTGGT
CAGTATCTCCAGTGAGCATCTGGAGCCCATCACCCCCACCAAGAACAACAAGGTGAAAGTGATT
CTGGGTGAGGACCGAGAGGCTACCGGGGTCCTTCTGAGTATTGATGGTGAGGATGGCATCATCC
GAATGGACCTGGAAGACCAGCAGATCAAGATTCTAAACCTCCGCTTCCTAGGGAAGCTCCTGGA
GGCCTGAGGCCCAAGCGTGCGGAGCAAGCAGCCCGCTCTGGCCTTGCTTGGCCTAGGATGGAAC
CCCGAGTCTGGGGCAAGCCAGGGCAATCACTCTGGATTTCCTTTTCCTCCTCCCCTGGTACTCT
AGGAATCAGAGCAGTCTGAGGAATGTCCTGCCTTCTTTCTGCTGTCCCAGCTTGCCTTTGTGTT
CAGGCCTTTCAATAAAGAGAAACTGTTTGAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039111567 ⟹ XP_038967495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,444 (-)	NCBI
mRatBN7.2	1	83,586,932 - 83,616,960 (-)	NCBI

RefSeq Acc Id:

XM_039111569 ⟹ XP_038967497

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,745,489 (-)	NCBI
mRatBN7.2	1	83,586,932 - 83,616,971 (-)	NCBI

RefSeq Acc Id:

XM_039111570 ⟹ XP_038967498

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,509 (-)	NCBI
mRatBN7.2	1	83,586,713 - 83,616,971 (-)	NCBI

RefSeq Acc Id:

XM_063261507 ⟹ XP_063117577

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,388 (-)	NCBI

RefSeq Acc Id:

XM_063261515 ⟹ XP_063117585

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,427 (-)	NCBI

RefSeq Acc Id:

XM_063261518 ⟹ XP_063117588

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,444 (-)	NCBI

RefSeq Acc Id:

XM_063261526 ⟹ XP_063117596

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,745,489 (-)	NCBI

RefSeq Acc Id:

XM_063261528 ⟹ XP_063117598

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	92,714,276 - 92,744,147 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100967	(Get FASTA)	NCBI Sequence Viewer
	XP_038967495	(Get FASTA)	NCBI Sequence Viewer
	XP_038967497	(Get FASTA)	NCBI Sequence Viewer
	XP_038967498	(Get FASTA)	NCBI Sequence Viewer
	XP_063117577	(Get FASTA)	NCBI Sequence Viewer
	XP_063117585	(Get FASTA)	NCBI Sequence Viewer
	XP_063117588	(Get FASTA)	NCBI Sequence Viewer
	XP_063117596	(Get FASTA)	NCBI Sequence Viewer
	XP_063117598	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB05843	(Get FASTA)	NCBI Sequence Viewer
	EDM07902	(Get FASTA)	NCBI Sequence Viewer
	EDM07903	(Get FASTA)	NCBI Sequence Viewer
	EDM07904	(Get FASTA)	NCBI Sequence Viewer
	EDM07905	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049521.6
	ENSRNOP00000076183
	ENSRNOP00000076183.3
	ENSRNOP00000076244
	ENSRNOP00000076244.2
	ENSRNOP00000081111
	ENSRNOP00000081111.2

RefSeq Acc Id:

NP_001100967 ⟸ NM_001107497

- UniProtKB:

A0A8I5ZQE4 (UniProtKB/TrEMBL), E9PTB2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSDSEDSNFSEEEDSERSSEAEEAEVEEDRRSAAGSEKEEEPEEEEEEEEEEYDEEEEEEDDDR
PPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLW
RDQREEELGEYYMKKYAKSSVGETVYGGSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATA
ISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPI
KEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS
LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEG
VKPTLSELEKFEDQPEGIDLEVVTESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKIT
IMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKV
LPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQ
KKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKAR
HLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEGQHGGFGSPGGMSRGRGRRDNELIGQT
VRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYGRTPMYGS
QTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYE
YAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGS
YQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNP
HTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEH
LEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA

hide sequence

Ensembl Acc Id:

ENSRNOP00000076244 ⟸ ENSRNOT00000093740

Ensembl Acc Id:

ENSRNOP00000076183 ⟸ ENSRNOT00000093384

Ensembl Acc Id:

ENSRNOP00000049521 ⟸ ENSRNOT00000048905

RefSeq Acc Id:	XP_038967498 ⟸ XM_039111570
- Peptide Label:	isoform X3
- UniProtKB:	A0A1W2Q6F0 (UniProtKB/TrEMBL), E9PTB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967497 ⟸ XM_039111569
- Peptide Label:	isoform X2
- UniProtKB:	A0A1W2Q689 (UniProtKB/TrEMBL), E9PTB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967495 ⟸ XM_039111567
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZQE4 (UniProtKB/TrEMBL), E9PTB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117596 ⟸ XM_063261526
- Peptide Label:	isoform X4
- UniProtKB:	E9PTB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117588 ⟸ XM_063261518
- Peptide Label:	isoform X2
- UniProtKB:	E9PTB2 (UniProtKB/TrEMBL), A0A1W2Q689 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117585 ⟸ XM_063261515
- Peptide Label:	isoform X2
- UniProtKB:	E9PTB2 (UniProtKB/TrEMBL), A0A1W2Q689 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117577 ⟸ XM_063261507
- Peptide Label:	isoform X1
- UniProtKB:	E9PTB2 (UniProtKB/TrEMBL), A0A8I5ZQE4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117598 ⟸ XM_063261528
- Peptide Label:	isoform X5
- UniProtKB:	E9PTB2 (UniProtKB/TrEMBL), A6J9H9 (UniProtKB/TrEMBL)

Protein Domains

KOW NusG-like N-terminal Spt5 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-E9PTB2-F1-model_v2	AlphaFold	E9PTB2	1-1083	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689878

Promoter ID:

EPDNEW_R399

Type:

initiation region

Name:

Supt5h_1

Description:

SPT5 homolog, DSIF elongation factor subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	85,437,802 - 85,437,862	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563807	AgrOrtholog
BioCyc Gene	G2FUF-60255	BioCyc
Ensembl Genes	ENSRNOG00000032034	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000048905.8	UniProtKB/TrEMBL
	ENSRNOT00000093383	ENTREZGENE
	ENSRNOT00000093383.3	UniProtKB/TrEMBL
	ENSRNOT00000093384	ENTREZGENE
	ENSRNOT00000093384.3	UniProtKB/TrEMBL
	ENSRNOT00000093740	ENTREZGENE
	ENSRNOT00000093740.3	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.30	UniProtKB/TrEMBL
	3.30.70.940	UniProtKB/TrEMBL
InterPro	KOW	UniProtKB/TrEMBL
	KOW_Spt5_1	UniProtKB/TrEMBL
	KOW_Spt5_2	UniProtKB/TrEMBL
	KOW_Spt5_3	UniProtKB/TrEMBL
	KOW_Spt5_4	UniProtKB/TrEMBL
	KOW_Spt5_5	UniProtKB/TrEMBL
	KOW_Spt5_6	UniProtKB/TrEMBL
	NGN_dom_sf	UniProtKB/TrEMBL
	NGN_Euk	UniProtKB/TrEMBL
	Rib_L2_dom2	UniProtKB/TrEMBL
	SPT5	UniProtKB/TrEMBL
	Spt5_C_dom	UniProtKB/TrEMBL
	Spt5_N	UniProtKB/TrEMBL
	TF_Spt5	UniProtKB/TrEMBL
	TF_Spt5_NGN-domain	UniProtKB/TrEMBL
	Transcrpt_antiterm_NusG_N	UniProtKB/TrEMBL
	Translation_prot_SH3-like	UniProtKB/TrEMBL
NCBI Gene	308472	ENTREZGENE
PANTHER	PTHR11125	UniProtKB/TrEMBL
	TRANSCRIPTION ELONGATION FACTOR SPT5	UniProtKB/TrEMBL
Pfam	KOW	UniProtKB/TrEMBL
	KOW1_SPT5	UniProtKB/TrEMBL
	KOW2_Spt5	UniProtKB/TrEMBL
	KOW4_SPT5	UniProtKB/TrEMBL
	KOW5_SPT5	UniProtKB/TrEMBL
	KOW6_SPT5	UniProtKB/TrEMBL
	KOW7_SPT5	UniProtKB/TrEMBL
	KOWx_SPT5	UniProtKB/TrEMBL
	Spt5-NGN	UniProtKB/TrEMBL
	Spt5_N	UniProtKB/TrEMBL
PhenoGen	Supt5h	PhenoGen
PIRSF	Spt5	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000032034	RatGTEx
SMART	CTD	UniProtKB/TrEMBL
	KOW	UniProtKB/TrEMBL
	NGN	UniProtKB/TrEMBL
Superfamily-SCOP	Transl_SH3_like	UniProtKB/TrEMBL
UniProt	A0A1W2Q689	ENTREZGENE, UniProtKB/TrEMBL
	A0A1W2Q6F0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZQE4	ENTREZGENE
	A0A8I5ZR84_RAT	UniProtKB/TrEMBL
	A6J9H9	ENTREZGENE, UniProtKB/TrEMBL
	A6J9I0_RAT	UniProtKB/TrEMBL
	A6J9I2_RAT	UniProtKB/TrEMBL
	E9PTB2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-10-07	Supt5h	SPT5 homolog, DSIF elongation factor subunit	Supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Supt5h	suppressor of Ty 5 homolog (S. cerevisiae)			Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	Supt5h	suppressor of Ty 5 homolog (S. cerevisiae)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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