Ces2h (carboxylesterase 2H) - Rat Genome Database

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Gene: Ces2h (carboxylesterase 2H) Rattus norvegicus
Analyze
Symbol: Ces2h
Name: carboxylesterase 2H
RGD ID: 1560889
Description: Predicted to enable carboxylesterase activity. Predicted to be involved in prostaglandin metabolic process. Orthologous to human CES2 (carboxylesterase 2); PARTICIPATES IN heroin pharmacodynamics pathway; heroin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: carboxylesterase 2; carboxylesterase 2 (intestine, liver); Ces2; LOC498940; similar to Carboxylesterase 2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81949,884,164 - 49,898,764 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1949,884,164 - 49,898,752 (+)EnsemblGRCr8
mRatBN7.21932,974,242 - 32,988,842 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1932,974,242 - 32,988,830 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,789,195 - 39,803,799 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,443,101 - 40,457,703 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,732,328 - 42,746,952 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,052,555 - 37,067,176 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,052,556 - 37,067,156 (+)Ensemblrn6Rnor6.0
Rnor_5.01947,917,775 - 47,932,375 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41934,910,981 - 34,925,547 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,403,472 - 32,418,072 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2-nitrophenyl)acetic acid  (ISO)
(4-nitrophenyl)acetic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one  (EXP)
2-arachidonoylglycerol  (ISO)
2-nitrofluorene  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-hydroxynon-2-enal  (ISO)
4-methylumbelliferyl acetate  (ISO)
5'-Deoxy-5-fluorocytidine  (ISO)
5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-acetylmorphine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
acridines  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-pinene  (ISO)
amiodarone  (EXP)
amitriptyline  (EXP)
aniracetam  (ISO)
arachidonic acid  (ISO)
azinphos-methyl  (ISO)
benzbromarone  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bis-4-nitrophenyl phosphate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A glycidylmethacrylate  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
cantharidin  (ISO)
capecitabine  (ISO)
CGP 52608  (ISO)
chloroform  (EXP)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clomipramine  (EXP)
clothianidin  (ISO)
cocaine  (ISO)
codeine  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyfluthrin  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
dextropropoxyphene  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dichlorvos  (EXP)
dimethyl sulfoxide  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enilconazole  (ISO)
epoxiconazole  (ISO)
erythromycin estolate  (EXP)
everolimus  (ISO)
finasteride  (EXP)
fipronil  (EXP)
fluconazole  (EXP)
fructose  (ISO)
furan  (EXP,ISO)
furfural  (ISO)
galanthamine  (ISO)
galanthamine Trifluoroacetic acid  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gemfibrozil  (EXP)
genistein  (ISO)
glucose  (ISO)
GSK-J4  (ISO)
herbicide  (ISO)
heroin  (ISO)
imipramine  (EXP)
indole-3-methanol  (EXP)
irinotecan  (ISO)
ketoconazole  (EXP)
kuwanone G  (ISO)
L-ethionine  (EXP)
lead(0)  (ISO)
lesinurad  (ISO)
lipopolysaccharide  (ISO)
loperamide  (ISO)
Magnolol  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxsalen  (ISO)
methylmercury chloride  (ISO)
methylprednisolone succinate  (EXP)
mitoxantrone  (ISO)
morphine  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nevirapine  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
oxybutynin  (ISO)
oxycodone  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP,ISO)
pethidine  (ISO)
Pf-06840003  (ISO)
phenobarbital  (EXP,ISO)
phenylmethanesulfonyl fluoride  (ISO)
physostigmine  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
procaine  (ISO)
propiconazole  (EXP,ISO)
prostaglandin F2alpha  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
riddelliine  (EXP)
rifampicin  (ISO)
rivastigmine  (ISO)
rotenone  (EXP)
Sanggenon C  (ISO)
Sanggenon D  (ISO)
SB 203580  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tacrine  (ISO)
tamoxifen  (EXP)
Tesaglitazar  (EXP)
testosterone enanthate  (ISO)
tetramethrin  (ISO)
thiacloprid  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triadimefon  (EXP,ISO)
triphenyl phosphate  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins. Holmes RS, etal., Mamm Genome. 2010 Oct;21(9-10):427-41. Epub 2010 Oct 8.
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides. Tully DB, etal., Toxicol Appl Pharmacol. 2006 Sep 15;215(3):260-73. Epub 2006 Apr 27.
Additional References at PubMed
PMID:12477932   PMID:19225040   PMID:21049984  


Genomics

Comparative Map Data
Ces2h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81949,884,164 - 49,898,764 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1949,884,164 - 49,898,752 (+)EnsemblGRCr8
mRatBN7.21932,974,242 - 32,988,842 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1932,974,242 - 32,988,830 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,789,195 - 39,803,799 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,443,101 - 40,457,703 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,732,328 - 42,746,952 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,052,555 - 37,067,176 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,052,556 - 37,067,156 (+)Ensemblrn6Rnor6.0
Rnor_5.01947,917,775 - 47,932,375 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41934,910,981 - 34,925,547 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,403,472 - 32,418,072 (+)NCBICelera
Cytogenetic Map19q11NCBI
CES2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381666,934,471 - 66,945,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1666,934,444 - 66,945,096 (+)Ensemblhg38GRCh38
GRCh371666,968,374 - 66,978,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,525,848 - 65,536,500 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341665,525,847 - 65,536,500NCBI
Celera1651,476,606 - 51,487,258 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1652,842,457 - 52,853,109 (+)NCBIHuRef
CHM1_11668,375,355 - 68,386,007 (+)NCBICHM1_1
T2T-CHM13v2.01672,728,771 - 72,739,396 (+)NCBIT2T-CHM13v2.0
Ces2h
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,727,462 - 105,747,042 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,727,485 - 105,747,810 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388105,000,830 - 105,020,410 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,000,853 - 105,021,178 (+)Ensemblmm10GRCm38
MGSCv378107,524,753 - 107,544,310 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368107,889,982 - 107,909,539 (+)NCBIMGSCv36mm8
Celera8109,223,262 - 109,242,859 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
CES2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,434,135 - 76,447,050 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,347,751 - 82,359,626 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,249,672 - 47,262,495 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,352,702 - 66,367,485 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,352,751 - 66,365,348 (+)EnsemblpanPan2panpan1.1
CES2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,370,524 - 82,383,682 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,372,529 - 82,384,154 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha582,359,222 - 82,372,464 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0582,807,139 - 82,820,377 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,808,343 - 82,820,374 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,632,490 - 82,644,573 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,317,150 - 82,330,407 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,956,034 - 82,969,336 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ces2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,109,486 - 42,136,394 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647517,452,749 - 17,460,880 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Variants

.
Variants in Ces2h
102 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000019072
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)194172060949971820Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat

Markers in Region
D19Rat53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21932,973,468 - 32,973,603 (+)MAPPERmRatBN7.2
Rnor_6.01937,051,805 - 37,051,937NCBIRnor6.0
Rnor_5.01947,917,004 - 47,917,136UniSTSRnor5.0
RGSC_v3.41934,910,173 - 34,910,308RGDRGSC3.4
RGSC_v3.41934,910,174 - 34,910,308UniSTSRGSC3.4
Celera1932,402,701 - 32,402,833UniSTS
RGSC_v3.11934,915,054 - 34,915,189RGD
FHH x ACI Map1930.2099RGD
FHH x ACI Map1930.2099UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
16 9 17 46 72 70 40 24 40 6 201 65 4 22 72 53 30

Sequence


Ensembl Acc Id: ENSRNOT00000019072   ⟹   ENSRNOP00000019072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1949,884,164 - 49,898,752 (+)Ensembl
mRatBN7.2 Ensembl1932,974,242 - 32,988,830 (+)Ensembl
Rnor_6.0 Ensembl1937,052,556 - 37,067,156 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000074399   ⟹   ENSRNOP00000065794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1932,974,242 - 32,988,830 (+)Ensembl
RefSeq Acc Id: NM_001044258   ⟹   NP_001037723
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,884,164 - 49,898,764 (+)NCBI
mRatBN7.21932,974,242 - 32,988,842 (+)NCBI
Rnor_6.01937,052,576 - 37,067,176 (+)NCBI
Rnor_5.01947,917,775 - 47,932,375 (+)NCBI
RGSC_v3.41934,910,981 - 34,925,547 (+)RGD
Celera1932,403,472 - 32,418,072 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001190346   ⟹   NP_001177275
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,884,164 - 49,898,764 (+)NCBI
mRatBN7.21932,974,242 - 32,988,842 (+)NCBI
Rnor_6.01937,052,576 - 37,067,176 (+)NCBI
Rnor_5.01947,917,775 - 47,932,375 (+)NCBI
Celera1932,403,472 - 32,418,072 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001037723 (Get FASTA)   NCBI Sequence Viewer  
  NP_001177275 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI07807 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019072
  ENSRNOP00000019072.5
  ENSRNOP00000065794.4
RefSeq Acc Id: NP_001037723   ⟸   NM_001044258
- Peptide Label: isoform 1 precursor
- UniProtKB: Q32Q55 (UniProtKB/TrEMBL),   M0R8J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001177275   ⟸   NM_001190346
- Peptide Label: isoform 2 precursor
- UniProtKB: Q32Q55 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019072   ⟸   ENSRNOT00000019072
Ensembl Acc Id: ENSRNOP00000065794   ⟸   ENSRNOT00000074399
Protein Domains
Carboxylesterase type B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q32Q55-F1-model_v2 AlphaFold Q32Q55 1-558 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701062
Promoter ID:EPDNEW_R11586
Type:initiation region
Name:Ces2h_1
Description:carboxylesterase 2H
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,052,593 - 37,052,653EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560889 AgrOrtholog
BioCyc Gene G2FUF-5861 BioCyc
BioCyc Pathway PWY-6857 [retinol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6857 BioCyc
Ensembl Genes ENSRNOG00000039079 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000052151 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019072 ENTREZGENE
  ENSRNOT00000019072.9 UniProtKB/TrEMBL
  ENSRNOT00000074399.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368719 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/TrEMBL
  CarbesteraseB UniProtKB/TrEMBL
  Carboxylesterase_B_AS UniProtKB/TrEMBL
  Carboxylesterase_B_CS UniProtKB/TrEMBL
  Type-B_Carboxylest/Lipase UniProtKB/TrEMBL
KEGG Report rno:498940 UniProtKB/TrEMBL
MGC_CLONE MGC:125054 IMAGE-MGC_LOAD
NCBI Gene 498940 ENTREZGENE
PANTHER CARBOXYLESTERASE UniProtKB/TrEMBL
Pfam COesterase UniProtKB/TrEMBL
PharmGKB CES2 RGD
PhenoGen Ces2h PhenoGen
PROSITE CARBOXYLESTERASE_B_1 UniProtKB/TrEMBL
  CARBOXYLESTERASE_B_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039079 RatGTEx
  ENSRNOG00000052151 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt M0R8J8 ENTREZGENE, UniProtKB/TrEMBL
  Q32Q55 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-11-18 Ces2h  carboxylesterase 2H  Ces2  carboxylesterase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-11-05 Ces2  carboxylesterase 2  Ces2  carboxylesterase 2 (intestine, liver)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-23 Ces2  carboxylesterase 2 (intestine, liver)  LOC498940  similar to Carboxylesterase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498940  similar to Carboxylesterase 2      Symbol and Name status set to provisional 70820 PROVISIONAL