Advanced Search (OLGA)

Gene: Slc16a12 (solute carrier family 16, member 12) Rattus norvegicus

Subscribe to Updates

Analyze

Symbol:

Slc16a12

Name:

solute carrier family 16, member 12

RGD ID:

1311468

Description:

Enables creatine transmembrane transporter activity. Involved in creatine transmembrane transport and creatinine metabolic process. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in cataract 47. Orthologous to human SLC16A12 (solute carrier family 16 member 12); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC309525; MCT 12; monocarboxylate transporter 12; RGD1311468; similar to expressed sequence AW210596; solute carrier family 16 (monocarboxylic acid transporters), member 12; solute carrier family 16, member 12 (monocarboxylic acid transporter 12)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC16A12 (solute carrier family 16 member 12)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc16a12 (solute carrier family 16 (monocarboxylic acid transporters), member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Slc16a12 (solute carrier family 16 (monocarboxylic acid transporters), member 12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC16A12 (solute carrier family 16 member 12)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc16a12a (solute carrier family 16 member 12a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc16a12b (solute carrier family 16 member 12b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11665	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	MCH5	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ESBP6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MCH2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG14196	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	MCH4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Mct1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA)
Caenorhabditis elegans (roundworm):	mct-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8389	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	mct-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8028	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG8034	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG8051	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	out	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Sln	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc16a12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Genetic Models:

F344-Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI		GRCr8
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	240,579,603 - 240,608,453 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	247,498,691 - 247,521,337 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	240,336,893 - 240,359,535 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	252,976,071 - 253,054,500 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	238,643,040 - 238,665,699 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	238,807,343 - 238,830,600 (-)	NCBI
Celera	1	229,298,962 - 229,321,612 (-)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	autoimmune lymphoproliferative syndrome		ISO	SLC16A12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME more ...	ClinVar	PMID:28492532
Slc16a12	Rat	cataract		ISO	SLC16A12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Congenital cataract	ClinVar	PMID:25741868 and PMID:26694549
Slc16a12	Rat	cataract 47		ISO	SLC16A12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:17458810 more ...
Slc16a12	Rat	coloboma		ISO	SLC16A12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Coloboma of eye	ClinVar	PMID:24281366 more ...
Slc16a12	Rat	Wolman disease		ISO	SLC16A12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Wolman disease	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	cataract 47		ISO	SLC16A12 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	cataract 47		ISO	SLC16A12 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	(+)-schisandrin B	multiple interactions	EXP		6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC16A12 mRNA]	CTD	PMID:31150632
Slc16a12	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of SLC16A12 mRNA	CTD	PMID:22206623
Slc16a12	Rat	17beta-estradiol	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of SLC16A12 mRNA	CTD	PMID:30165855
Slc16a12	Rat	17beta-estradiol	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Estradiol results in decreased expression of SLC16A12 mRNA	CTD	PMID:39298647
Slc16a12	Rat	17beta-estradiol	affects expression	EXP		6480464	Estradiol affects the expression of SLC16A12 mRNA	CTD	PMID:32145629
Slc16a12	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of SLC16A12 mRNA	CTD	PMID:22298810
Slc16a12	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in decreased expression of SLC16A12 mRNA	CTD	PMID:33956508
Slc16a12	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of SLC16A12 mRNA	CTD	PMID:28922406
Slc16a12	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Tetrachlorodibenzodioxin results in decreased expression of SLC16A12 mRNA	CTD	PMID:26159488
Slc16a12	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC16A12 mRNA]	CTD	PMID:26159488
Slc16a12	Rat	2-methylcholine	affects expression	ISO	SLC16A12 (Homo sapiens)	6480464	beta-methylcholine affects the expression of SLC16A12 mRNA	CTD	PMID:21179406
Slc16a12	Rat	2-palmitoylglycerol	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	2-palmitoylglycerol results in increased expression of SLC16A12 mRNA	CTD	PMID:37199045
Slc16a12	Rat	3,3',4,4'-tetrachlorobiphenyl	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	3 more ...	CTD	PMID:19467301
Slc16a12	Rat	3-chloropropane-1,2-diol	increases expression	EXP		6480464	alpha-Chlorohydrin results in increased expression of SLC16A12 mRNA	CTD	PMID:28522335
Slc16a12	Rat	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SLC16A12 mRNA	CTD	PMID:28628672
Slc16a12	Rat	4,4'-diaminodiphenylmethane	decreases expression	EXP		6480464	4 and 4'-diaminodiphenylmethane results in decreased expression of SLC16A12 mRNA	CTD	PMID:30723492
Slc16a12	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	bisphenol S results in increased expression of SLC16A12 mRNA	CTD	PMID:30951980
Slc16a12	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	bisphenol S results in decreased expression of SLC16A12 mRNA	CTD	PMID:39298647
Slc16a12	Rat	4-hydroxyphenyl retinamide	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Fenretinide results in decreased expression of SLC16A12 mRNA	CTD	PMID:28973697
Slc16a12	Rat	acetamide	decreases expression	EXP		6480464	acetamide results in decreased expression of SLC16A12 mRNA	CTD	PMID:31881176
Slc16a12	Rat	aflatoxin B1	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Aflatoxin B1 results in increased expression of SLC16A12 mRNA	CTD	PMID:19770486
Slc16a12	Rat	aflatoxin B1	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased expression of SLC16A12 mRNA	CTD	PMID:22100608 and PMID:32234424
Slc16a12	Rat	aristolochic acid A	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of SLC16A12 mRNA	CTD	PMID:33212167
Slc16a12	Rat	benzo[a]pyrene	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of SLC16A12 mRNA	CTD	PMID:27195522
Slc16a12	Rat	benzo[a]pyrene	increases methylation	ISO	SLC16A12 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of SLC16A12 exon and Benzo(a)pyrene results in increased methylation of SLC16A12 promoter	CTD	PMID:27901495
Slc16a12	Rat	benzo[a]pyrene	decreases methylation	ISO	SLC16A12 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of SLC16A12 3' UTR	CTD	PMID:27901495
Slc16a12	Rat	benzo[a]pyrene	affects methylation	ISO	SLC16A12 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of SLC16A12 5' UTR	CTD	PMID:27901495
Slc16a12	Rat	bilirubin IXalpha	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Bilirubin results in decreased expression of SLC16A12 mRNA	CTD	PMID:20196124
Slc16a12	Rat	bisphenol A	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	bisphenol A results in decreased expression of SLC16A12 mRNA	CTD	PMID:26063408
Slc16a12	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of SLC16A12 mRNA	CTD	PMID:32145629
Slc16a12	Rat	bisphenol A	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	bisphenol A results in increased expression of SLC16A12 mRNA	CTD	PMID:31715268
Slc16a12	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of SLC16A12 gene	CTD	PMID:28505145
Slc16a12	Rat	bisphenol A	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	bisphenol A results in increased expression of SLC16A12 mRNA	CTD	PMID:25594700
Slc16a12	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of SLC16A12 mRNA	CTD	PMID:25181051 and PMID:34947998
Slc16a12	Rat	bisphenol F	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SLC16A12 mRNA	CTD	PMID:28628672
Slc16a12	Rat	bisphenol F	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	bisphenol F results in increased expression of SLC16A12 mRNA	CTD	PMID:30951980
Slc16a12	Rat	cadmium atom	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Cadmium results in decreased expression of SLC16A12 mRNA	CTD	PMID:24376830
Slc16a12	Rat	cadmium atom	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SLC16A12 mRNA	CTD	PMID:35301059
Slc16a12	Rat	cadmium dichloride	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SLC16A12 mRNA	CTD	PMID:35301059
Slc16a12	Rat	carbon nanotube	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Nanotubes and Carbon analog results in increased expression of SLC16A12 mRNA	CTD	PMID:25620056
Slc16a12	Rat	cefaloridine	decreases expression	EXP		6480464	Cephaloridine results in decreased expression of SLC16A12 mRNA	CTD	PMID:18500788
Slc16a12	Rat	CGP 52608	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to SLC16A12 gene]	CTD	PMID:28238834
Slc16a12	Rat	chloropicrin	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	chloropicrin results in increased expression of SLC16A12 mRNA	CTD	PMID:26352163 and PMID:28476498
Slc16a12	Rat	chloroprene	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Chloroprene results in increased expression of SLC16A12 mRNA	CTD	PMID:23125180
Slc16a12	Rat	chlorpyrifos	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Chlorpyrifos results in increased expression of SLC16A12 mRNA	CTD	PMID:37019170
Slc16a12	Rat	chromium(6+)	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	chromium hexavalent ion affects the expression of SLC16A12 mRNA	CTD	PMID:28472532
Slc16a12	Rat	cisplatin	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Cisplatin results in increased expression of SLC16A12 mRNA	CTD	PMID:27392435
Slc16a12	Rat	cyproconazole	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	cyproconazole results in increased expression of SLC16A12 mRNA	CTD	PMID:22334560
Slc16a12	Rat	dexamethasone	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SLC16A12 mRNA	CTD	PMID:28628672
Slc16a12	Rat	doxorubicin	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of SLC16A12 mRNA	CTD	PMID:29803840
Slc16a12	Rat	endosulfan	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC16A12 mRNA]	CTD	PMID:26159488
Slc16a12	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of SLC16A12 mRNA	CTD	PMID:29391264
Slc16a12	Rat	epoxiconazole	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	epoxiconazole results in increased expression of SLC16A12 mRNA	CTD	PMID:22334560
Slc16a12	Rat	epoxiconazole	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	epoxiconazole affects the expression of SLC16A12 mRNA	CTD	PMID:35436446
Slc16a12	Rat	flutamide	decreases expression	EXP		6480464	Flutamide results in decreased expression of SLC16A12 mRNA	CTD	PMID:24793618
Slc16a12	Rat	fonofos	increases methylation	ISO	SLC16A12 (Homo sapiens)	6480464	Fonofos results in increased methylation of SLC16A12 promoter	CTD	PMID:22847954
Slc16a12	Rat	hydrogen peroxide	affects expression	ISO	SLC16A12 (Homo sapiens)	6480464	Hydrogen Peroxide affects the expression of SLC16A12 mRNA	CTD	PMID:21179406
Slc16a12	Rat	hydroxyurea	increases mutagenesis	ISO	Slc16a12 (Mus musculus)	6480464	Hydroxyurea results in increased mutagenesis of SLC16A12 gene	CTD	PMID:16868089
Slc16a12	Rat	indometacin	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SLC16A12 mRNA	CTD	PMID:28628672
Slc16a12	Rat	inulin	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SLC16A12 mRNA	CTD	PMID:36331819
Slc16a12	Rat	N-methyl-N-nitrosourea	increases mutagenesis	ISO	Slc16a12 (Mus musculus)	6480464	Methylnitrosourea results in increased mutagenesis of SLC16A12 gene	CTD	PMID:16868089
Slc16a12	Rat	nickel sulfate	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	nickel sulfate results in decreased expression of SLC16A12 mRNA	CTD	PMID:22714537
Slc16a12	Rat	O-methyleugenol	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	methyleugenol results in decreased expression of SLC16A12 mRNA	CTD	PMID:32234424
Slc16a12	Rat	ozone	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SLC16A12 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SLC16A12 mRNA	CTD	PMID:34911549
Slc16a12	Rat	paracetamol	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	Acetaminophen affects the expression of SLC16A12 mRNA	CTD	PMID:17562736
Slc16a12	Rat	paraquat	decreases expression	EXP		6480464	Paraquat results in decreased expression of SLC16A12 mRNA	CTD	PMID:32680482
Slc16a12	Rat	parathion	increases methylation	ISO	SLC16A12 (Homo sapiens)	6480464	Parathion results in increased methylation of SLC16A12 promoter	CTD	PMID:22847954
Slc16a12	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	perfluorohexanesulfonic acid results in decreased expression of SLC16A12 mRNA	CTD	PMID:37995155
Slc16a12	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SLC16A12 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SLC16A12 mRNA	CTD	PMID:36331819
Slc16a12	Rat	phenobarbital	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	Phenobarbital results in increased expression of SLC16A12 mRNA	CTD	PMID:19270015
Slc16a12	Rat	phenobarbital	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	Phenobarbital affects the expression of SLC16A12 mRNA	CTD	PMID:23091169
Slc16a12	Rat	potassium dichromate	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Potassium Dichromate results in decreased expression of SLC16A12 mRNA	CTD	PMID:23608068
Slc16a12	Rat	propiconazole	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	propiconazole results in increased expression of SLC16A12 mRNA	CTD	PMID:22334560
Slc16a12	Rat	resveratrol	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	Resveratrol inhibits the reaction [titanium dioxide results in increased expression of SLC16A12 mRNA]	CTD	PMID:31298478
Slc16a12	Rat	resveratrol	multiple interactions	ISO	SLC16A12 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of SLC16A12 mRNA	CTD	PMID:23557933
Slc16a12	Rat	rifampicin	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Rifampin results in increased expression of SLC16A12 mRNA	CTD	PMID:24552687
Slc16a12	Rat	rifampicin	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Rifampin results in decreased expression of SLC16A12 mRNA	CTD	PMID:27199754
Slc16a12	Rat	senecionine	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	senecionine results in decreased expression of SLC16A12 protein	CTD	PMID:35357534
Slc16a12	Rat	silver atom	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Silver results in decreased expression of SLC16A12 mRNA	CTD	PMID:27131904
Slc16a12	Rat	silver(0)	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Silver results in decreased expression of SLC16A12 mRNA	CTD	PMID:27131904
Slc16a12	Rat	sodium arsenite	increases expression	ISO	SLC16A12 (Homo sapiens)	6480464	sodium arsenite results in increased expression of SLC16A12 mRNA	CTD	PMID:29301061 and PMID:38568856
Slc16a12	Rat	sodium arsenite	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	sodium arsenite results in decreased expression of SLC16A12 mRNA	CTD	PMID:37682722
Slc16a12	Rat	succimer	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SLC16A12 mRNA	CTD	PMID:23086747
Slc16a12	Rat	terbufos	increases methylation	ISO	SLC16A12 (Homo sapiens)	6480464	terbufos results in increased methylation of SLC16A12 promoter	CTD	PMID:22847954
Slc16a12	Rat	tetrachloromethane	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	Carbon Tetrachloride results in decreased expression of SLC16A12 mRNA	CTD	PMID:27339419
Slc16a12	Rat	tetrachloromethane	affects expression	ISO	Slc16a12 (Mus musculus)	6480464	Carbon Tetrachloride affects the expression of SLC16A12 mRNA	CTD	PMID:31919559
Slc16a12	Rat	tetrachloromethane	decreases expression	EXP		6480464	Carbon Tetrachloride results in decreased expression of SLC16A12 mRNA	CTD	PMID:31150632
Slc16a12	Rat	tetrachloromethane	multiple interactions	EXP		6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC16A12 mRNA]	CTD	PMID:31150632
Slc16a12	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of SLC16A12 mRNA	CTD	PMID:34492290
Slc16a12	Rat	titanium dioxide	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	titanium dioxide results in decreased expression of SLC16A12 mRNA	CTD	PMID:29264374
Slc16a12	Rat	titanium dioxide	decreases methylation	ISO	Slc16a12 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of SLC16A12 gene	CTD	PMID:35295148
Slc16a12	Rat	titanium dioxide	multiple interactions	ISO	Slc16a12 (Mus musculus)	6480464	Resveratrol inhibits the reaction [titanium dioxide results in increased expression of SLC16A12 mRNA]	CTD	PMID:31298478
Slc16a12	Rat	titanium dioxide	increases expression	ISO	Slc16a12 (Mus musculus)	6480464	titanium dioxide results in increased expression of SLC16A12 mRNA	CTD	PMID:31298478
Slc16a12	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of SLC16A12 mRNA	CTD	PMID:33387578
Slc16a12	Rat	triclosan	decreases expression	ISO	SLC16A12 (Homo sapiens)	6480464	Triclosan results in decreased expression of SLC16A12 mRNA	CTD	PMID:30510588
Slc16a12	Rat	trimellitic anhydride	decreases expression	ISO	Slc16a12 (Mus musculus)	6480464	trimellitic anhydride results in decreased expression of SLC16A12 mRNA	CTD	PMID:19042947
Slc16a12	Rat	valproic acid	increases expression	EXP		6480464	Valproic Acid results in increased expression of SLC16A12 mRNA	CTD	PMID:29427782

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	biological_process		ND		1598407	12/2009: no relevant rat data	RGD
Slc16a12	Rat	creatine transmembrane transport	involved_in	IDA		153298943	PMID:34075817	UniProt
Slc16a12	Rat	creatine transmembrane transport	involved_in	IEA	UniProtKB:Q6ZSM3 and ensembl:ENSP00000360855	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc16a12	Rat	creatine transmembrane transport	involved_in	IBA	PANTHER:PTN008516712 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc16a12	Rat	creatine transmembrane transport	involved_in	ISO	SLC16A12 (Homo sapiens)	1624291	PMID:23578822 more ...	RGD	PMID:23578822 more ...
Slc16a12	Rat	creatinine metabolic process	involved_in	IDA		153298943	PMID:34075817	UniProt
Slc16a12	Rat	transmembrane transport	involved_in	IEA	InterPro:IPR011701	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	basolateral plasma membrane	located_in	IDA		153298943	PMID:34075817	UniProt
Slc16a12	Rat	basolateral plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0026	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Slc16a12	Rat	basolateral plasma membrane	located_in	ISO	Slc16a12 (Mus musculus)	1624291	PMID:26376857	RGD	PMID:26376857
Slc16a12	Rat	basolateral plasma membrane	located_in	IEA	UniProtKB:Q8BGC3 and ensembl:ENSMUSP00000009522	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc16a12	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc16a12	Rat	plasma membrane	located_in	ISO	SLC16A12 (Homo sapiens)	1624291	PMID:21778275 more ...	RGD	PMID:21778275 more ...
Slc16a12	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Slc16a12	Rat	plasma membrane	is_active_in	IBA	FB:FBgn0033028 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc16a12	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc16a12	Rat	plasma membrane	located_in	IEA	UniProtKB:Q6ZSM3 and ensembl:ENSP00000360855	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc16a12	Rat	creatine transmembrane transporter activity	enables	IDA		153298943	PMID:34075817	UniProt
Slc16a12	Rat	creatine transmembrane transporter activity	enables	IEA	UniProtKB:Q6ZSM3 and ensembl:ENSP00000360855	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc16a12	Rat	creatine transmembrane transporter activity	enables	ISO	SLC16A12 (Homo sapiens)	1624291	PMID:23578822 more ...	RGD	PMID:23578822 more ...
Slc16a12	Rat	protein binding	enables	ISO	SLC16A12 (Homo sapiens)	1624291	UniProtKB:P11912 more ...	RGD	PMID:32296183
Slc16a12	Rat	transmembrane transporter activity	enables	IEA	InterPro:IPR011701 and InterPro:IPR020846	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc16a12	Rat	transmembrane transporter activity	enables	IBA	FB:FBgn0033028 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc16a12	Rat	uniporter activity	enables	ISO	SLC16A12 (Homo sapiens)	1624291	PMID:32249133	RGD	PMID:32249133
Slc16a12	Rat	uniporter activity	enables	IEA	UniProtKB:Q6ZSM3 and ensembl:ENSP00000360855	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc16a12	Rat	uniporter activity	enables	ISS	UniProtKB:Q6ZSM3	1600115	GO_REF:0000024	UniProt	GO_REF:0000024

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Contribution of monocarboxylate transporter 12 to blood supply of creatine on the sinusoidal membrane of the hepatocytes.	Jomura R, etal., Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1;321(2):G113-G122. doi: 10.1152/ajpgi.00143.2021. Epub 2021 Jun 2.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:21778275	PMID:23578822	PMID:32781157	PMID:33459166

Slc16a12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI		GRCr8
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	240,579,603 - 240,608,453 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	247,498,691 - 247,521,337 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	240,336,893 - 240,359,535 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	252,976,071 - 253,054,500 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	238,643,040 - 238,665,699 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	238,807,343 - 238,830,600 (-)	NCBI
Celera	1	229,298,962 - 229,321,612 (-)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

SLC16A12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	89,430,299 - 89,556,704 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	89,430,299 - 89,556,641 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	91,190,056 - 91,295,351 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	91,180,036 - 91,285,293 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	84,936,860 - 85,042,126 (-)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	84,824,228 - 84,929,593 (-)	NCBI		HuRef
CHM1_1	10	91,472,067 - 91,577,412 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	90,314,133 - 90,419,429 (-)	NCBI		T2T-CHM13v2.0

Slc16a12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	34,645,801 - 34,725,223 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	34,645,803 - 34,724,689 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	34,668,401 - 34,747,493 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	34,668,403 - 34,747,289 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	34,742,896 - 34,821,601 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	34,734,403 - 34,813,108 (-)	NCBI		MGSCv36	mm8
Celera	19	35,442,689 - 35,521,028 (-)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	29.79	NCBI

Slc16a12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	3,509,142 - 3,560,138 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	3,474,814 - 3,560,138 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC16A12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	101,446,803 - 101,481,472 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	101,452,146 - 101,486,786 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	86,155,527 - 86,187,917 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	89,696,148 - 89,727,585 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	89,696,148 - 89,727,585 (-)	Ensembl	panpan1.1		panPan2

SLC16A12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	4,343,773 - 4,430,653 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	4,345,546 - 4,421,234 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	4,579,217 - 4,664,998 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	4,565,289 - 4,652,174 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	4,567,687 - 4,651,465 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	4,323,134 - 4,402,863 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	4,365,926 - 4,445,342 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	4,501,245 - 4,580,912 (-)	NCBI		UU_Cfam_GSD_1.0

Slc16a12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	43,114,853 - 43,133,513 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	4,747,489 - 4,763,697 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	4,685,215 - 4,766,116 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC16A12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	101,273,996 - 101,368,132 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	101,273,977 - 101,368,350 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	110,262,470 - 110,354,305 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC16A12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	82,817,476 - 82,917,004 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	82,818,994 - 82,916,837 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	43,493,620 - 43,592,283 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc16a12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	312,039 - 365,915 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	312,039 - 405,432 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Slc16a12
515 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	48
Interacting mature miRNAs:	53
Transcripts:	ENSRNOT00000030024
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8693637	Alc29	Alcohol consumption QTL 29	2.7	0.258	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	1	207987464	234238494	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	197814409	242814409	Rat
2302375	Bw83	Body weight QTL 83	4.87	0.0002	body mass (VT:0001259)	body weight (CMO:0000012)	1	197697768	242697768	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	201554356	246554356	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
61455	Niddm7	Non-insulin dependent diabetes mellitus QTL 7	5.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	214537555	238757011	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	216255568	260522016	Rat
1600392	Bw123	Body weight QTL 123		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	223201027	260522016	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	123556856	242907031	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	201554356	246554356	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	228581588	259647894	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	224054293	260122809	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	191019702	246062233	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	225126575	260522016	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	224054293	260122809	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	201554356	246554356	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	221264111	259647894	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	213707201	252085212	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	201554356	246554356	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	197814409	242814409	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	193113876	238113876	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	224569538	260122809	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	218753816	256448513	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	8e-07	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	196248093	241248093	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	197814409	242814409	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
1549910	Bw54	Body weight QTL 54		0.05	body mass (VT:0001259)	body weight (CMO:0000012)	1	214647894	259647894	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	214647894	259647894	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	222363780	260522016	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228985440	245907899	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
10053715	Scort24	Serum corticosterone level QTL 24	2.13	0.0088	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	221414816	260522016	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	210702053	240947965	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	218753689	245907899	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
2292216	Bw80	Body weight QTL 80	3.23	0.0019	body mass (VT:0001259)	body weight (CMO:0000012)	1	213533809	243914901	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	191033875	236033875	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	197697768	238755659	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	196248093	241248093	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	224054293	243747962	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	224054293	243747962	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	223262787	260522016	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	197670404	242670404	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	232156370	259647894	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	203995416	244113296	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	192825253	243914732	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	216255568	260522016	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	201554356	246554356	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	218748008	257976495	Rat

RH139695

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	232,261,919 - 232,262,109 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	253,054,145 - 253,054,334	NCBI	Rnor6.0
Rnor_5.0	1	260,275,712 - 260,275,901	UniSTS	Rnor5.0
RGSC_v3.4	1	238,718,730 - 238,718,919	UniSTS	RGSC3.4
Celera	1	229,374,607 - 229,374,796	UniSTS
RH 3.4 Map	4	511.02	UniSTS
Cytogenetic Map	1	q52	UniSTS

This gene Slc16a12 is modified in the following models/strains:

F344-Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001191637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC128768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030024 ⟹ ENSRNOP00000038838

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl

RefSeq Acc Id:

NM_001191637 ⟹ NP_001178566

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,599,066 - 241,621,716 (-)	NCBI
mRatBN7.2	1	232,185,907 - 232,208,555 (-)	NCBI
Rnor_6.0	1	252,977,974 - 253,000,624 (-)	NCBI
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI
Celera	1	229,298,962 - 229,321,612 (-)	NCBI

Sequence:

show sequence

ATGACGAAGATAACTAGAGTTGGTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTGTGGCCGGCTGCTTTCTTGTTACCATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTT
TGTGGAGTTTCAGACGTACTTTGCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTAGACTGCATGACAATGCTCTGTGCTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAG
CGGGGATCATGCTGGGTGGCTTGCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAGTTTGAAGCACCTCTACCTCAGTCTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCC
CCAGCAATTGCCATGGTGGGCAAGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCATGTCAGGCAGTGGCATTGGTACCTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTT
CTCCTGGCGAGGAGCACTGCTCATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCGCTGATGCGTCCAATTACCCTTAAAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACG
CTCAGAGAGAAGACTGTAAGCAGGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGACCCGTCTTTGCTGCTCTTTGCAGCAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTG
GCTGTCTCTGTTCTGTTCATGGCCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATGCTTTGAGTGTCGGAGTGAGTCACCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGA
TATTGTCGGCAACATCACGTTTGGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATATGTTTGCTACCTCTTTGCTGTGGCACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAA
GCTTCCCCCTTCTTGTGCCTTTCTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTTGATCCCAGTAGTGACTGCAGAGATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTC
TACTTCCTCCATGCAGTGCCATACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGACGGGCAGCTATACTGCAGCCTTCCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCT
TGGCTTTGCCAAAATTGCAAAAAGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCAGATCCCAAGCTGCATCTGTGGACCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATC
AGAAAGATGAGGAATCCCTGGCTAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCCTTGTCCTGGGAATCTGCAAGGCTGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATA
TTTTATTTTGACAGAGTATCACCTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTATATGGGGACAATAATGAGCAACAAAGAAATCTGGAGTTAGCCTGGAGTTTTCTCATTCAGGATTT
GTACTCACTACAAACTTAGCTCTGGGAGAAGGGCAGGACACAGTTGACAGGGTCAGTTGTATTTCAGGACAACTCTAAGCAGAGGCCACTGTGAAGAGTTTTCATAAAATCTGCCCCACCCCCTCATT
CTGAACAGAAGCAGTGGTGGTTGTGCTGGCAGTGGGGATGCAGAGGTGACTTGAGAACAGAGCGCCTCAATGTTTAGAGTGGCA

hide sequence

RefSeq Acc Id:

XM_017589300 ⟹ XP_017444789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,597,165 - 241,674,078 (-)	NCBI
mRatBN7.2	1	232,186,279 - 232,262,170 (-)	NCBI
Rnor_6.0	1	252,978,244 - 253,054,500 (-)	NCBI

Sequence:

show sequence

GGGGATGGCTAGCTAGGAAACTGCAGGACAGATGCCTCCTGGAGGGCGGGGCAAACACCATTTACCCTCCACTGTTAAGGAACCTGGCACCCCATTTTTTCTTCAGCAGGAGCAAACTTTGTTTTTAT
TTTATTGAGAAACTGAGACCAAGTGAACTGTTTAAAGTCATAGAGTTTGCGAGCGAGTTGAACTCAAGTCCTTAGGACTGATTGATGTGTGCAGTGGTCTGACCAGGGTCCTGGTCCTTGCCAGATGC
CGGTGCAGGAGACTTTGAACAGCTTCTACTCTCTGACCATTCAGGGACATAGTCTTCTGGAGAACACCCAGGCACTCCTTTAGTGTAGGTCCCAGGCACACAGGGCTGTTCCAGAGAGAGCCCTGCAA
GTCCCTAGTGGGCTGGCTCGTGACTCGGCGGGCCGGCCGGGCCGGAGCATTACATAACCTGGAGGCGCCCCTCCTCCGTGGCCGAGCCCCCAGCGCAGAGCGGATCCGGGGACAAGGCCAGTCTGGCA
GCAGGGCAGAGTCACCCTCGGGGCTGGCGTCACTGAGAGCCTTGGTTCTCCGGGGCGGGGCGGTGGGATCTCCTCAGTGACAGTGTCCGGCGGGCTCTGCCTGTGGCCCCGGCCCCTACGGCGCCTCC
GCCCCGTGCGCACCCCGCCCCTCGGCCGGACCGGACTCCAGGGGCCGTGGGAAGGGGCCGCCGTGCAGGGGGCATGTGGGCTCACCGTCGCCAGCTCTGCAGCTGTCCCCGCGAGTGCAAGCTGATGA
TTCAGCGTTCCGAACCACTCGCTCGCGTTTTGTCTGGACGCTGGTTCGTTCTTCCCAGCTTTGCTGAGAGCTATGTGGGCAATTCCAGCGGCTCTGCTGACCTAGTCCAGAAGGAAAAATCTTCAGGC
TTGCCAAGTTCAGGAAGACCCCGTGGCTACAGATGGGCAGTAATCCCTGTGCCAGGTAGCATCCTGAACCAACTTTGAGGATCAACAGGAAGTTGCTGGGTAGCAACCACTGAGGATCCTAACTTACT
GCTGCAGTGACCTGGAAAGAGAAGAAAACCAAAATTGCAACCATGACGAAGATAACTAGAGTTGGTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTGTGGCCGGCTGCTTTCTTGTTAC
CATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTTTGTGGAGTTTCAGACGTACTTTGCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTAGACTGCATGACAATGCTCTGTG
CTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAGCGGGGATCATGCTGGGTGGCTTGCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAGTTTGAAGCACCTCTACCTCAGT
CTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCCCCAGCAATTGCCATGGTGGGCAAGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCATGTCAGGCAGTGGCATTGGTAC
CTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTTCTCCTGGCGAGGAGCACTGCTCATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCGCTGATGCGTCCAATTACCCTTA
AAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACGCTCAGAGAGAAGACTGTAAGCAGGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGACCCGTCTTTGCTGCTCTTTGCAG
CAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTGGCTGTCTCTGTTCTGTTCATGGCCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATGCTTTGAGTGTCGGAGTGAGTCA
CCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGATATTGTCGGCAACATCACGTTTGGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATATGTTTGCTACCTCTTTGCTGTGG
CACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAAGCTTCCCCCTTCTTGTGCCTTTCTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTTGATCCCAGTAGTGACTGCAGAG
ATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTCTACTTCCTCCATGCAGTGCCATACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGACGGGCAGCTATACTGCAGCCTT
CCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCTTGGCTTTGCCAAAATTGCAAAAAGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCAGATCCCAAGCTGCATCTGTGGA
CCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATCAGAAAGATGAGGAATCCCTGGCTAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCCTTGTCCTGGGAATCTGCAAGGC
TGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATATTTTATTTTGACAGAGTATCACCTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTATATGGGG

hide sequence

RefSeq Acc Id:

XM_017589301 ⟹ XP_017444790

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI
Rnor_6.0	1	252,978,244 - 253,054,500 (-)	NCBI

Sequence:

show sequence

GGGGATGGCTAGCTAGGAAACTGCAGGACAGATGCCTCCTGGAGGGCGGGGCAAACACCATTTACCCTCCACTGTTAAGGAACCTGGCACCCCATTTTTTCTTCAGCAGGAGCAAACTTTGTTTTTAT
TTTATTGAGAAACTGAGACCAAGTGAACTGTTTAAAGTCATAGAGTTTGCGAGCGAGTTGAACTCAAGTCCTTAGGACTGATTGATGTGTGCAGTGGTCTGACCAGGGTCCTGGTCCTTGCCAGATGC
CGGTGCAGGAGACTTTGAACAGCTTCTACTCTCTGACCATTCAGGGACATAGTCTTCTGGAGAACACCCAGGCACTCCTTTAGTGTAGGTCCCAGGCACACAGGGCTGTTCCAGAGAGAGCCCTGCAA
GTCCCTAGTGGGCTGGCTCGTGACTCGGCGGGCCGGCCGGGCCGGAGCATTACATAACCTGGAGGCGCCCCTCCTCCGTGGCCGAGCCCCCAGCGCAGAGCGGATCCGGGGACAAGGCCAGTCTGGCA
GCAGGGCAGAGTCACCCTCGGGGCTGGCGTCACTGAGAGCCTTGGTTCTCCGGGGCGGGGCGGTGGGATCTCCTCAGTGACAGTGTCCGGCGGGCTCTGCCTGTGGCCCCGGCCCCTACGGCGCCTCC
GCCCCGTGCGCACCCCGCCCCTCGGCCGGACCGGACTCCAGGGGCCGTGGGAAGGGGCCGCCGTGCAGGGGGCATGTGGGCTCACCGTCGCCAGCTCTGCAGCTGTCCCCGCGAGATGGGCAGTAATC
CCTGTGCCAGGTAGCATCCTGAACCAACTTTGAGGATCAACAGGAAGTTGCTGGGTAGCAACCACTGAGGATCCTAACTTACTGCTGCAGTGACCTGGAAAGAGAAGAAAACCAAAATTGCAACCATG
ACGAAGATAACTAGAGTTGGTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTGTGGCCGGCTGCTTTCTTGTTACCATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTTTGT
GGAGTTTCAGACGTACTTTGCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTAGACTGCATGACAATGCTCTGTGCTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAGCGG
GGATCATGCTGGGTGGCTTGCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAGTTTGAAGCACCTCTACCTCAGTCTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCCCCA
GCAATTGCCATGGTGGGCAAGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCATGTCAGGCAGTGGCATTGGTACCTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTTCTC
CTGGCGAGGAGCACTGCTCATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCGCTGATGCGTCCAATTACCCTTAAAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACGCTC
AGAGAGAAGACTGTAAGCAGGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGACCCGTCTTTGCTGCTCTTTGCAGCAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTGGCT
GTCTCTGTTCTGTTCATGGCCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATGCTTTGAGTGTCGGAGTGAGTCACCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGATAT
TGTCGGCAACATCACGTTTGGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATATGTTTGCTACCTCTTTGCTGTGGCACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAAGCT
TCCCCCTTCTTGTGCCTTTCTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTTGATCCCAGTAGTGACTGCAGAGATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTCTAC
TTCCTCCATGCAGTGCCATACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGACGGGCAGCTATACTGCAGCCTTCCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCTTGG
CTTTGCCAAAATTGCAAAAAGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCAGATCCCAAGCTGCATCTGTGGACCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATCAGA
AAGATGAGGAATCCCTGGCTAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCCTTGTCCTGGGAATCTGCAAGGCTGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATATTT
TATTTTGACAGAGTATCACCTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTATATGGGG

hide sequence


Protein RefSeqs	NP_001178566	(Get FASTA)	NCBI Sequence Viewer
	XP_017444789	(Get FASTA)	NCBI Sequence Viewer
	XP_017444790	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4A734	(Get FASTA)	NCBI Sequence Viewer
	EDM13169	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000038838
	ENSRNOP00000038838.3
	ENSRNOP00000104843

RefSeq Acc Id:

NP_001178566 ⟸ NM_001191637

- UniProtKB:

D4A734 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS
PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL
AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV
YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT

hide sequence

RefSeq Acc Id:	XP_017444790 ⟸ XM_017589301
- Peptide Label:	isoform X1
- UniProtKB:	D4A734 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT hide sequence

RefSeq Acc Id:	XP_017444789 ⟸ XM_017589300
- Peptide Label:	isoform X1
- UniProtKB:	D4A734 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT hide sequence

Ensembl Acc Id:

ENSRNOP00000038838 ⟸ ENSRNOT00000030024

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A734-F1-model_v2	AlphaFold	D4A734	1-486	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-55866	BioCyc
Ensembl Genes	ENSRNOG00000021916	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000030024	ENTREZGENE
	ENSRNOT00000030024.6	UniProtKB/Swiss-Prot
	ENSRNOT00000167047	ENTREZGENE
Gene3D-CATH	1.20.1250.20	UniProtKB/Swiss-Prot
InterPro	MFS	UniProtKB/Swiss-Prot
	MFS_dom	UniProtKB/Swiss-Prot
	MFS_trans_sf	UniProtKB/Swiss-Prot
	Proton-linked_MCT	UniProtKB/Swiss-Prot
KEGG Report	rno:309525	UniProtKB/Swiss-Prot
NCBI Gene	309525	ENTREZGENE
PANTHER	MONOCARBOXYLATE TRANSPORTER	UniProtKB/Swiss-Prot
	MONOCARBOXYLATE TRANSPORTER 12	UniProtKB/Swiss-Prot
Pfam	MFS_1	UniProtKB/Swiss-Prot
PhenoGen	Slc16a12	PhenoGen
PROSITE	MFS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021916	RatGTEx
Superfamily-SCOP	SSF103473	UniProtKB/Swiss-Prot
UniProt	D4A734	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-19	Slc16a12	solute carrier family 16, member 12 (monocarboxylic acid transporter 12)	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	Slc16a12_predicted	solute carrier family 16 (monocarboxylic acid transporters), member 12 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Slc16a12_predicted	solute carrier family 16 (monocarboxylic acid transporters), member 12 (predicted)	RGD1311468_predicted	similar to expressed sequence AW210596 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1311468_predicted	similar to expressed sequence AW210596 (predicted)	LOC309525_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC309525_predicted	similar to expressed sequence AW210596 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM