Advanced Search (OLGA)

Gene: Eef1b2 (eukaryotic translation elongation factor 1 beta 2) Rattus norvegicus

Analyze

Symbol:

Eef1b2

Name:

eukaryotic translation elongation factor 1 beta 2

RGD ID:

1311415

Description:

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in response to ethanol. Predicted to be located in endoplasmic reticulum. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Orthologous to human EEF1B2 (eukaryotic translation elongation factor 1 beta 2); PARTICIPATES IN translation elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

eEF-1B alpha; EF-1-beta; elongation factor 1-beta; LOC363241

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	EEF1B2 (eukaryotic translation elongation factor 1 beta 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	eef1b2 (eukaryotic translation elongation factor 1 beta 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	eef-1B.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	EFB1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	EFB1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	eEF1beta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	eEF1beta	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	eef-1B.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	eef-1B.1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	eef1b2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	eef1b2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	72,074,091 - 72,076,591 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	72,073,802 - 72,076,589 (+)	Ensembl				GRCr8
mRatBN7.2	9	64,580,163 - 64,582,737 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	64,579,893 - 64,582,737 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	73,083,686 - 73,086,186 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	78,204,606 - 78,207,106 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	76,511,237 - 76,513,737 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	69,953,440 - 69,956,158 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	69,953,440 - 69,956,160 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	69,762,337 - 69,765,055 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	61,832,222 - 61,834,940 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	61,998,041 - 62,000,759 (+)	NCBI		Celera
RGSC_v3.1	9	61,979,375 - 61,981,932 (+)	NCBI
Cytogenetic Map	9	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (ISO)

Developmental Disabilities (ISO)

epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Neoplasm Metastasis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

acetamide (EXP)

acrolein (ISO)

actinomycin D (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

CU-O LINKAGE (ISO)

deguelin (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (EXP)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

furfural (ISO)

gentamycin (EXP)

glafenine (EXP)

hydrogen sulfide (ISO)

indometacin (ISO)

inulin (ISO)

ivermectin (ISO)

lead(II) chloride (ISO)

methidathion (ISO)

miconazole (ISO)

mono(2-ethylhexyl) phthalate (ISO)

monobenzyl phthalate (ISO)

Monobutylphthalate (ISO)

monoethyl phthalate (ISO)

nefazodone (EXP)

nimesulide (EXP)

nitric oxide (ISO)

Nutlin-3 (ISO)

ozone (EXP,ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

picoxystrobin (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

pyrimidifen (ISO)

pyrogallol (ISO)

quercetin (ISO)

rotenone (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

sodium chloride (ISO)

sodium dichromate (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

tungsten (ISO)

valproic acid (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to ethanol (IDA)

translation (IEA)

translational elongation (IEA)

Cellular Component

cytoplasm (IEA,ISO)

endoplasmic reticulum (IEA,ISO)

eukaryotic translation elongation factor 1 complex (IEA)

nucleus (ISO)

Molecular Function

protein binding (ISO)

translation elongation factor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

translation elongation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The elongation, termination, and recycling phases of translation in eukaryotes.	Dever TE and Green R, Cold Spring Harb Perspect Biol. 2012 Jul 1;4(7):a013706. doi: 10.1101/cshperspect.a013706.
2.	Prenatal alcohol exposure alters phosphorylation and glycosylation of proteins in rat offspring liver.	Fofana B, etal., Proteomics. 2010 Feb;10(3):417-34. doi: 10.1002/pmic.200800969.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:8743958	PMID:12426392	PMID:12477932	PMID:24625528	PMID:25002582	PMID:28131823	PMID:35352799

Genomics

Comparative Map Data

Eef1b2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	72,074,091 - 72,076,591 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	72,073,802 - 72,076,589 (+)	Ensembl				GRCr8
mRatBN7.2	9	64,580,163 - 64,582,737 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	64,579,893 - 64,582,737 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	73,083,686 - 73,086,186 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	78,204,606 - 78,207,106 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	76,511,237 - 76,513,737 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	69,953,440 - 69,956,158 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	69,953,440 - 69,956,160 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	69,762,337 - 69,765,055 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	61,832,222 - 61,834,940 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	61,998,041 - 62,000,759 (+)	NCBI		Celera
RGSC_v3.1	9	61,979,375 - 61,981,932 (+)	NCBI
Cytogenetic Map	9	q32	NCBI

EEF1B2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	206,159,609 - 206,162,928 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	206,159,585 - 206,162,932 (+)	Ensembl			hg38	GRCh38
GRCh37	2	207,024,333 - 207,027,652 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	206,732,563 - 206,735,898 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	206,849,839 - 206,853,157	NCBI
Celera	2	200,781,747 - 200,785,083 (+)	NCBI		Celera
Cytogenetic Map	2	q33.3	NCBI
HuRef	2	198,872,898 - 198,876,236 (+)	NCBI		HuRef
CHM1_1	2	207,030,874 - 207,034,213 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	206,641,502 - 206,644,822 (+)	NCBI		T2T-CHM13v2.0

Eef1b2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	63,215,990 - 63,219,645 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	63,215,984 - 63,219,645 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	63,176,831 - 63,180,486 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	63,176,825 - 63,180,486 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	63,223,405 - 63,227,060 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	63,099,699 - 63,113,932 (+)	NCBI		MGSCv36	mm8
Celera	1	63,687,221 - 63,690,876 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	32.31	NCBI

Eef1b2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	8,835,121 - 8,837,816 (-)	Ensembl
ChiLan1.0	NW_004955457	8,835,121 - 8,837,816 (-)	NCBI	ChiLan1.0	ChiLan1.0

EEF1B2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	108,773,675 - 108,776,640 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	108,788,618 - 108,791,622 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	93,399,413 - 93,402,779 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	211,528,491 - 211,531,826 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	211,528,497 - 211,531,826 (+)	Ensembl			panPan2	panpan1.1

EEF1B2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	14,713,927 - 14,716,894 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	14,714,017 - 14,716,850 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	15,590,671 - 15,593,638 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	14,649,290 - 14,652,257 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	14,649,380 - 14,652,213 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	14,603,540 - 14,606,497 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	14,575,797 - 14,578,764 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	14,572,093 - 14,575,060 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Eef1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	162,904,145 - 162,907,175 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936631	2,539,070 - 2,542,419 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936631	2,539,075 - 2,542,252 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EEF1B2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	109,451,514 - 109,455,525 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	109,451,901 - 109,455,529 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	121,000,537 - 121,004,164 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EEF1B2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	91,927,639 - 91,930,972 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	107,448,123 - 107,451,477 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eef1b2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	9,958,907 - 9,962,108 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624765	9,958,908 - 9,962,074 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Eef1b2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	137,164,988 - 137,167,758 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Eef1b2
15 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	74
Count of miRNA genes:	67
Interacting mature miRNAs:	70
Transcripts:	ENSRNOT00000034740
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56047863	101047863	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	40029925	85029925	Rat
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	63376862	108376862	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	44458256	99506504	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	65657365	108376720	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	29567664	74567664	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	44458256	85262605	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	29567664	83835942	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	41720295	86720295	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	64220169	109220169	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	44458256	121768150	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	64220169	109220169	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	64220169	109220169	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	39220186	84220186	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	68875497	121768150	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	48718864	108376862	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	40029925	85029925	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	57460497	78547958	Rat
1578659	Tspe1	Trichinella spiralis expulsion QTL 1	4.8		parasite quantity (VT:0010441)	logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)	9	68875497	73185088	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	54506504	99506504	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	64220169	109220169	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	34960590	79960590	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC168738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034740 ⟹ ENSRNOP00000036882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	72,073,802 - 72,076,589 (+)	Ensembl
mRatBN7.2 Ensembl	9	64,580,009 - 64,582,733 (+)	Ensembl
Rnor_6.0 Ensembl	9	69,953,440 - 69,956,160 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113520 ⟹ ENSRNOP00000091436

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	72,074,095 - 72,076,589 (+)	Ensembl
mRatBN7.2 Ensembl	9	64,579,893 - 64,582,737 (+)	Ensembl

RefSeq Acc Id:

NM_001108799 ⟹ NP_001102269

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	72,074,091 - 72,076,591 (+)	NCBI
mRatBN7.2	9	64,580,237 - 64,582,737 (+)	NCBI
Rnor_6.0	9	69,953,440 - 69,956,158 (+)	NCBI
Rnor_5.0	9	69,762,337 - 69,765,055 (+)	NCBI
RGSC_v3.4	9	61,832,222 - 61,834,940 (+)	RGD
Celera	9	61,998,041 - 62,000,759 (+)	RGD

Sequence:

show sequence

CCTTTAGTTTTAGAATCCTTGGAGGTAGGCGTTTTAAAATGCATCTTTTATTAATTTCCTTCCA
AACACAAGGAAAAGCCCGCGGACGACCTGTGGGTCGTCTAATTCACAAGACGCAGTTTTACGTG
AAGGAACGAGACTAGTAACGTACTTTGACCTTTAACCTCTAGCCGGTGCAGTGGAGGGAAACGC
CTCCGTCTCTATATAAGGACTTTTCCGGCCGGTCCCGGCCCTTTTTCTCCCTCAGCGCTGGCCG
CGGGCTTCTAGCGCTCTTTTCCTCCGCTCCCGGTTACAGTCGACGCCATGGGTTTCGGAGACCT
GAAAACCCCCGCCGGCCTCCAGGTGCTCAACGATTACCTGGCGGACAAGAGCTACATTGAGGGG
TACGTGCCATCACAAGCCGATGTGGCAGTATTTGAAGCAATCTCTGGTCCACCACCCGCTGACC
TGTGTCATGCTCTGCGTTGGTATAATCATATCAAATCTTACGAAAAAGAAAAGGCCAGCTTGCC
GGGAGTGAAGAAATCTTTGGGCAAGTATGGCCCTGTCAGTGTGGCAGATACCACAGGAAGTGGA
GCAGCAGATGCTAAAGACGATGATGACATTGATCTCTTCGGATCTGATGATGAGGAGGAAAGTG
AAGACGCAAAGAGGCTACGAGAAGAACGCCTTGCTCAGTATGAGTCAAAGAAAGCTAAAAAGCC
TGCAGTTGTTGCGAAGTCTTCCATCTTGTTAGATGTGAAGCCTTGGGACGATGAGACAGACATG
ACGAAACTTGAGGAGTGTGTCCGAAGCATTCAAGCGGACGGCTTGGTGTGGGGCTCCTCTAAAT
TGGTTCCAGTGGGATACGGAATTAAAAAGCTTCAAATACAGTGTGTAGTTGAAGATGATAAGGT
TGGAACAGATATGCTGGAAGAGCAGATTACTGCTTTTGAGGACTATGTACAGTCCATGGATGTG
GCTGCTTTTAACAAAATCTAAATCATCCTTAAGTCTGTGCACTTAAATAAAAGCTCGAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102269	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A6IPG1	(Get FASTA)	NCBI Sequence Viewer
	AAI68738	(Get FASTA)	NCBI Sequence Viewer
	EDL98899	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000036882
	ENSRNOP00000036882.4
	ENSRNOP00055031112
	ENSRNOP00060028311
	ENSRNOP00065040184

RefSeq Acc Id:

NP_001102269 ⟸ NM_001108799

- UniProtKB:

B5DEN5 (UniProtKB/TrEMBL), A6IPG1 (UniProtKB/TrEMBL), A0A8I6AEG7 (UniProtKB/TrEMBL), F6SZC1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAISGPPPADLCHALRWYNHIKSYEK
EKASLPGVKKSLGKYGPVSVADTTGSGAADAKDDDDIDLFGSDDEEESEDAKRLREERLAQYES
KKAKKPAVVAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCV
VEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI

hide sequence

Ensembl Acc Id:

ENSRNOP00000036882 ⟸ ENSRNOT00000034740

Ensembl Acc Id:

ENSRNOP00000091436 ⟸ ENSRNOT00000113520

Protein Domains

GST C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DEN5-F1-model_v2	AlphaFold	B5DEN5	1-225	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696711

Promoter ID:

EPDNEW_R7236

Type:

multiple initiation site

Name:

Eef1b2_1

Description:

eukaryotic translation elongation factor 1 beta 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	69,953,671 - 69,953,731	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311415	AgrOrtholog
BioCyc Gene	G2FUF-27352	BioCyc
Ensembl Genes	ENSRNOG00000024186	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055022192	UniProtKB/Swiss-Prot
	ENSRNOG00060019898	UniProtKB/Swiss-Prot
	ENSRNOG00065028431	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000034740	ENTREZGENE
	ENSRNOT00000034740.5	UniProtKB/Swiss-Prot
	ENSRNOT00055038198	UniProtKB/Swiss-Prot
	ENSRNOT00060034485	UniProtKB/Swiss-Prot
	ENSRNOT00065048998	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1050.130	UniProtKB/Swiss-Prot
	3.30.70.60	UniProtKB/Swiss-Prot
InterPro	eEF-1beta-like_sf	UniProtKB/Swiss-Prot
	EF-1_beta_acid_region_euk	UniProtKB/Swiss-Prot
	EF1B_bsu/dsu	UniProtKB/Swiss-Prot
	EF1B_bsu/dsu_GNE	UniProtKB/Swiss-Prot
	Glutathione-S-Trfase_C_sf	UniProtKB/Swiss-Prot
	Transl_elong_EF1B/ribsomal_bS6	UniProtKB/Swiss-Prot
	Transl_elong_EF1B_B/D_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:363241	UniProtKB/Swiss-Prot
NCBI Gene	363241	ENTREZGENE
PANTHER	EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER	UniProtKB/Swiss-Prot
	ELONGATION FACTOR 1-BETA	UniProtKB/Swiss-Prot
Pfam	EF-1_beta_acid	UniProtKB/Swiss-Prot
	EF1_GNE	UniProtKB/Swiss-Prot
PhenoGen	Eef1b2	PhenoGen
PROSITE	EF1BD_1	UniProtKB/Swiss-Prot
	EF1BD_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000024186	RatGTEx
	ENSRNOG00055022192	RatGTEx
	ENSRNOG00060019898	RatGTEx
	ENSRNOG00065028431	RatGTEx
SMART	EF-1_beta_acid	UniProtKB/Swiss-Prot
	EF1_GNE	UniProtKB/Swiss-Prot
Superfamily-SCOP	eEF-1beta-like	UniProtKB/Swiss-Prot
	GST C-terminal domain-like	UniProtKB/Swiss-Prot
UniProt	A0A8I6AEG7	ENTREZGENE, UniProtKB/TrEMBL
	A6IPG1	ENTREZGENE
	B5DEN5	ENTREZGENE
	EF1B_RAT	UniProtKB/Swiss-Prot
	F6SZC1	ENTREZGENE
UniProt Secondary	B5DEN5	UniProtKB/Swiss-Prot
	F6SZC1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Eef1b2	eukaryotic translation elongation factor 1 beta 2	Eef1b2_predicted	eukaryotic translation elongation factor 1 beta 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Eef1b2_predicted	eukaryotic translation elongation factor 1 beta 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations