EEF1B2 (eukaryotic translation elongation factor 1 beta 2) - Rat Genome Database

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Pathways
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Gene: EEF1B2 (eukaryotic translation elongation factor 1 beta 2) Canis lupus familiaris
Analyze
Symbol: EEF1B2
Name: eukaryotic translation elongation factor 1 beta 2
RGD ID: 12134710
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); translation elongation factor activity (inferred); INVOLVED IN response to ethanol (ortholog); PARTICIPATES IN translation elongation pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Developmental Disabilities (ortholog); epilepsy (ortholog); FOUND IN endoplasmic reticulum (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation factor 1-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13714,713,927 - 14,716,894 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3714,714,017 - 14,716,850 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3715,590,671 - 15,593,638 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03714,649,290 - 14,652,257 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3714,649,380 - 14,652,213 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13714,603,540 - 14,606,497 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03714,575,797 - 14,578,764 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03714,572,093 - 14,575,060 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EEF1B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13714,713,927 - 14,716,894 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3714,714,017 - 14,716,850 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3715,590,671 - 15,593,638 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03714,649,290 - 14,652,257 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3714,649,380 - 14,652,213 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13714,603,540 - 14,606,497 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03714,575,797 - 14,578,764 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03714,572,093 - 14,575,060 (+)NCBIUU_Cfam_GSD_1.0
EEF1B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382206,159,609 - 206,162,928 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2206,159,585 - 206,162,928 (+)EnsemblGRCh38hg38GRCh38
GRCh372207,024,333 - 207,027,652 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362206,732,563 - 206,735,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 342206,849,839 - 206,853,157NCBI
Celera2200,781,747 - 200,785,083 (+)NCBICelera
Cytogenetic Map2q33.3NCBI
HuRef2198,872,898 - 198,876,236 (+)NCBIHuRef
CHM1_12207,030,874 - 207,034,213 (+)NCBICHM1_1
T2T-CHM13v2.02206,641,502 - 206,644,822 (+)NCBIT2T-CHM13v2.0
Eef1b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39163,215,990 - 63,219,645 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl163,215,984 - 63,219,645 (+)EnsemblGRCm39 Ensembl
GRCm38163,176,831 - 63,180,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl163,176,825 - 63,180,486 (+)EnsemblGRCm38mm10GRCm38
MGSCv37163,223,405 - 63,227,060 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36163,099,699 - 63,113,932 (+)NCBIMGSCv36mm8
Celera163,687,221 - 63,690,876 (+)NCBICelera
Cytogenetic Map1C2NCBI
cM Map132.31NCBI
Eef1b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8972,074,091 - 72,076,591 (+)NCBIGRCr8
mRatBN7.2964,580,163 - 64,582,737 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl964,579,893 - 64,582,737 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx973,083,686 - 73,086,186 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0978,204,606 - 78,207,106 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0976,511,237 - 76,513,737 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0969,953,440 - 69,956,158 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl969,953,440 - 69,956,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0969,762,337 - 69,765,055 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4961,832,222 - 61,834,940 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1961,979,375 - 61,981,932 (+)NCBI
Celera961,998,041 - 62,000,759 (+)NCBICelera
Cytogenetic Map9q32NCBI
Eef1b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554578,835,121 - 8,837,816 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554578,835,121 - 8,837,816 (-)NCBIChiLan1.0ChiLan1.0
EEF1B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213108,773,675 - 108,776,640 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B108,788,618 - 108,791,622 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B93,399,413 - 93,402,779 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B211,528,491 - 211,531,826 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B211,528,497 - 211,531,826 (+)Ensemblpanpan1.1panPan2
Eef1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303162,904,145 - 162,907,175 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366312,539,070 - 2,542,419 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366312,539,075 - 2,542,252 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EEF1B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15109,451,514 - 109,455,525 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115109,451,901 - 109,455,529 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215121,000,537 - 121,004,164 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EEF1B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11091,927,639 - 91,930,972 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040107,448,123 - 107,451,477 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eef1b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247659,958,907 - 9,962,108 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247659,958,908 - 9,962,074 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EEF1B2
30 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000043208   ⟹   ENSCAFP00000037938
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3714,714,017 - 14,716,850 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845036712   ⟹   ENSCAFP00845028742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3714,649,380 - 14,652,213 (+)Ensembl
RefSeq Acc Id: XM_038447747   ⟹   XP_038303675
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03714,649,290 - 14,652,257 (+)NCBI
RefSeq Acc Id: XM_038521801   ⟹   XP_038377729
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13714,603,540 - 14,606,497 (+)NCBI
RefSeq Acc Id: XM_038585510   ⟹   XP_038441438
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03714,572,093 - 14,575,060 (+)NCBI
RefSeq Acc Id: XM_038649904   ⟹   XP_038505832
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03714,575,797 - 14,578,764 (+)NCBI
RefSeq Acc Id: XM_536040   ⟹   XP_536040
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13714,713,927 - 14,716,894 (+)NCBI
Dog10K_Boxer_Tasha3715,590,671 - 15,593,638 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_536040   ⟸   XM_536040
- UniProtKB: A0A8C0RFS6 (UniProtKB/TrEMBL),   A0A8C0QSY7 (UniProtKB/TrEMBL),   A0A8I3PJ02 (UniProtKB/TrEMBL),   A0A8P0TTN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037938   ⟸   ENSCAFT00000043208
RefSeq Acc Id: XP_038377729   ⟸   XM_038521801
RefSeq Acc Id: XP_038505832   ⟸   XM_038649904
RefSeq Acc Id: XP_038303675   ⟸   XM_038447747
- UniProtKB: A0A8C0RFS6 (UniProtKB/TrEMBL),   A0A8C0QSY7 (UniProtKB/TrEMBL),   A0A8I3PJ02 (UniProtKB/TrEMBL),   A0A8P0TTN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441438   ⟸   XM_038585510
- UniProtKB: A0A8C0QSY7 (UniProtKB/TrEMBL),   A0A8C0RFS6 (UniProtKB/TrEMBL),   A0A8I3PJ02 (UniProtKB/TrEMBL),   A0A8P0TTN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028742   ⟸   ENSCAFT00845036712
Protein Domains
Elongation factor 1 beta central acidic region   Translation elongation factor EF1B beta/delta

Promoters
RGD ID:13689130
Promoter ID:EPDNEW_C7197
Type:initiation region
Name:EEF1B2_1
Description:eukaryotic translation elongation factor 1 beta 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13714,714,265 - 14,714,325EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029635 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008794 UniProtKB/TrEMBL
  ENSCAFG00040025669 UniProtKB/TrEMBL
  ENSCAFG00845020822 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043208.3 UniProtKB/TrEMBL
  ENSCAFT00000102289.1 UniProtKB/TrEMBL
  ENSCAFT00030016222.1 UniProtKB/TrEMBL
  ENSCAFT00040047913.1 UniProtKB/TrEMBL
  ENSCAFT00845036712 ENTREZGENE
  ENSCAFT00845036712.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.130 UniProtKB/TrEMBL
  3.30.70.60 UniProtKB/TrEMBL
InterPro eEF-1beta-like_sf UniProtKB/TrEMBL
  EF-1_beta_acid_region_euk UniProtKB/TrEMBL
  EF1B_bsu/dsu UniProtKB/TrEMBL
  EF1B_bsu/dsu_GNE UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/TrEMBL
  Transl_elong_EF1B/ribosomal_S6 UniProtKB/TrEMBL
  Transl_elong_EF1B_B/D_CS UniProtKB/TrEMBL
KEGG Report cfa:478881 UniProtKB/TrEMBL
NCBI Gene EEF1B2 ENTREZGENE
PANTHER EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER UniProtKB/TrEMBL
  ELONGATION FACTOR 1-BETA UniProtKB/TrEMBL
Pfam EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
PROSITE EF1BD_1 UniProtKB/TrEMBL
  EF1BD_2 UniProtKB/TrEMBL
SMART EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/TrEMBL
  SSF54984 UniProtKB/TrEMBL
UniProt A0A8C0QSY7 ENTREZGENE
  A0A8C0RFS6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PJ02 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TTN3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:57381 ENTREZGENE