Rel (REL proto-oncogene, NF-kB subunit) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rel (REL proto-oncogene, NF-kB subunit) Rattus norvegicus
Analyze
Symbol: Rel
Name: REL proto-oncogene, NF-kB subunit
RGD ID: 1311231
Description: Enables sequence-specific DNA binding activity. Predicted to be involved in several processes, including intracellular signaling cassette; positive regulation of canonical NF-kappaB signal transduction; and regulation of gene expression. Predicted to act upstream of or within positive regulation of DNA-templated transcription and positive regulation of interleukin-12 production. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 92. Orthologous to human REL (REL proto-oncogene, NF-kB subunit); PARTICIPATES IN nuclear factor kappa B signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305584; proto-oncogene c-Rel; reticuloendotheliosis oncogene; v-rel avian reticuloendotheliosis viral oncogene homolog; v-rel reticuloendotheliosis viral oncogene homolog; v-rel reticuloendotheliosis viral oncogene homolog (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,891,238 - 101,922,324 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14101,891,243 - 101,921,938 (-)EnsemblGRCr8
mRatBN7.21497,690,105 - 97,721,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1497,695,161 - 97,720,892 (-)EnsemblmRatBN7.2
Rnor_6.014108,490,794 - 108,517,582 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14108,491,069 - 108,509,892 (-)Ensemblrn6Rnor6.0
Rnor_5.014108,212,714 - 108,238,553 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414104,645,370 - 104,671,275 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1496,671,067 - 96,689,938 (-)NCBICelera
RGSC_v3.114104,664,855 - 104,689,687 (-)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(R)-noradrenaline  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-tert-butylhydroquinone  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
9-cis,11-trans-octadecadienoic acid  (ISO)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphotericin B  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
bathocuproine disulfonic acid  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon monoxide  (ISO)
carmustine  (EXP)
CCCP  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
crocidolite asbestos  (ISO)
curcumin  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
fluvastatin  (ISO)
formaldehyde  (ISO)
fucoidan  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
ionomycin  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
lipoarabinomannan  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
LY294002  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nystatin  (ISO)
o-anisidine  (ISO)
oxybenzone  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperine  (ISO)
protein kinase inhibitor  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
resveratrol  (ISO)
ritonavir  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
scoparone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
tacrolimus hydrate  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trifluoperazine  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (EXP,ISO)
wortmannin  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA,IEA,ISO)
nucleus  (IBA,IDA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice. Burkitt MD, etal., J Pathol. 2015 Jul;236(3):326-36. doi: 10.1002/path.4527. Epub 2015 Apr 21.
2. Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice. Burkitt MD, etal., Oncogene. 2013 Dec 12;32(50):5563-73. doi: 10.1038/onc.2013.334. Epub 2013 Aug 26.
3. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Cogswell PC, etal., Oncogene. 2000 Feb 24;19(9):1123-31.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Shared principles in NF-kappaB signaling. Hayden MS and Ghosh S, Cell. 2008 Feb 8;132(3):344-62.
7. S100B potently activates p65/c-Rel transcriptional complexes in hippocampal neurons: Clinical implications for the role of S100B in excitotoxic brain injury. Kogel D, etal., Neuroscience. 2004;127(4):913-20.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma. Pallares J, etal., J Pathol. 2004 Dec;204(5):569-77.
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta. Pizzi M, etal., J Biol Chem. 2002 Jun 7;277(23):20717-23. Epub 2002 Mar 23.
12. NF-kappaB is activated in the rat testis following exposure to mono-(2-ethylhexyl) phthalate. Rasoulpour RJ and Boekelheide K, Biol Reprod. 2005 Feb;72(2):479-86. Epub 2004 Oct 20.
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors. Romieu-Mourez R, etal., Mol Cell Biol. 2003 Aug;23(16):5738-54.
16. [Expression of NF-kappa B in human bladder cancer and its clinical significance] Xie DH, etal., Ai Zheng. 2002 Jun;21(6):663-7.
Additional References at PubMed
PMID:1406630   PMID:12761501   PMID:14568984   PMID:15197457   PMID:15220916   PMID:21874024   PMID:21984552   PMID:22065573   PMID:23564451   PMID:24605601   PMID:24853588  


Genomics

Comparative Map Data
Rel
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,891,238 - 101,922,324 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14101,891,243 - 101,921,938 (-)EnsemblGRCr8
mRatBN7.21497,690,105 - 97,721,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1497,695,161 - 97,720,892 (-)EnsemblmRatBN7.2
Rnor_6.014108,490,794 - 108,517,582 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14108,491,069 - 108,509,892 (-)Ensemblrn6Rnor6.0
Rnor_5.014108,212,714 - 108,238,553 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414104,645,370 - 104,671,275 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1496,671,067 - 96,689,938 (-)NCBICelera
RGSC_v3.114104,664,855 - 104,689,687 (-)NCBI
Cytogenetic Map14q22NCBI
REL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38260,881,574 - 60,931,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl260,881,491 - 60,931,612 (+)Ensemblhg38GRCh38
GRCh37261,108,709 - 61,158,747 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36260,962,256 - 61,003,682 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34261,020,402 - 61,061,829NCBI
Celera260,952,347 - 60,993,771 (+)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef260,850,654 - 60,892,025 (+)NCBIHuRef
CHM1_1261,039,153 - 61,080,572 (+)NCBICHM1_1
T2T-CHM13v2.0260,887,420 - 60,937,448 (+)NCBIT2T-CHM13v2.0
Rel
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391123,686,847 - 23,720,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1123,686,847 - 23,720,970 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381123,736,847 - 23,770,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1123,736,847 - 23,770,970 (-)Ensemblmm10GRCm38
MGSCv371123,641,729 - 23,670,970 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361123,641,990 - 23,670,970 (-)NCBIMGSCv36mm8
Celera1125,863,742 - 25,892,886 (-)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.36NCBI
Rel
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542422,911,541 - 22,939,651 (-)Ensembl
ChiLan1.0NW_00495542422,909,035 - 22,939,651 (-)NCBIChiLan1.0ChiLan1.0
REL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21265,446,373 - 65,496,842 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A65,458,688 - 65,500,793 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A60,972,022 - 61,013,562 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A62,113,581 - 62,155,241 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A62,113,581 - 62,155,241 (+)EnsemblpanPan2panpan1.1
REL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11060,990,264 - 61,030,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1060,990,197 - 61,023,663 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1060,878,772 - 60,922,447 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01061,997,356 - 62,041,015 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1061,997,563 - 62,030,500 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11061,697,560 - 61,740,683 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01061,984,931 - 62,028,604 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01062,277,508 - 62,321,170 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rel
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629222,137,080 - 22,165,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364916,405,515 - 6,436,510 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364916,405,493 - 6,435,096 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl380,872,255 - 80,911,939 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1380,861,862 - 80,912,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2384,966,717 - 85,003,490 (-)NCBISscrofa10.2Sscrofa10.2susScr3
REL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11446,068,212 - 46,097,226 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1446,068,014 - 46,096,802 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604565,685,304 - 65,731,499 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rel
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248331,022,656 - 1,053,342 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248331,016,330 - 1,053,514 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rel
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11193,202,509 - 93,228,653 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rel
415 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:18
Count of miRNA genes:15
Interacting mature miRNAs:17
Transcripts:ENSRNOT00000065110
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat

Markers in Region
D14Mco4  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr814101,917,160 - 101,917,438 (+)Marker Load Pipeline
mRatBN7.21497,716,027 - 97,716,305 (+)MAPPERmRatBN7.2
Rnor_6.014108,512,381 - 108,512,658NCBIRnor6.0
Rnor_5.014108,233,527 - 108,233,804UniSTSRnor5.0
RGSC_v3.414104,666,765 - 104,667,043RGDRGSC3.4
RGSC_v3.414104,666,766 - 104,667,043UniSTSRGSC3.4
Celera1496,690,945 - 96,691,222UniSTS
RGSC_v3.114104,685,976 - 104,686,254RGD
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000081077   ⟹   ENSRNOP00000072332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14101,891,243 - 101,921,938 (-)Ensembl
mRatBN7.2 Ensembl1497,695,407 - 97,720,892 (-)Ensembl
Rnor_6.0 Ensembl14108,491,069 - 108,509,892 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100608   ⟹   ENSRNOP00000089353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14101,895,559 - 101,921,938 (-)Ensembl
mRatBN7.2 Ensembl1497,695,161 - 97,720,892 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112858   ⟹   ENSRNOP00000077372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1497,695,161 - 97,714,500 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115747   ⟹   ENSRNOP00000110639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14101,891,243 - 101,921,938 (-)Ensembl
RefSeq Acc Id: NM_001421314   ⟹   NP_001408243
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814101,891,238 - 101,921,938 (-)NCBI
mRatBN7.21497,690,105 - 97,720,806 (-)NCBI
RefSeq Acc Id: XM_039092882   ⟹   XP_038948810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814101,891,238 - 101,922,324 (-)NCBI
mRatBN7.21497,690,105 - 97,721,194 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001408243 (Get FASTA)   NCBI Sequence Viewer  
  XP_038948810 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL97996 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072332
  ENSRNOP00000072332.3
  ENSRNOP00000089353
  ENSRNOP00000089353.2
  ENSRNOP00000110639.1
Ensembl Acc Id: ENSRNOP00000072332   ⟸   ENSRNOT00000081077
RefSeq Acc Id: XP_038948810   ⟸   XM_039092882
- Peptide Label: isoform X1
- UniProtKB: F1M5R1 (UniProtKB/TrEMBL),   A0A8I5XW27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077372   ⟸   ENSRNOT00000112858
Ensembl Acc Id: ENSRNOP00000089353   ⟸   ENSRNOT00000100608
RefSeq Acc Id: NP_001408243   ⟸   NM_001421314
- UniProtKB: A0A8I5XW27 (UniProtKB/TrEMBL),   A0A8I6ABJ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110639   ⟸   ENSRNOT00000115747

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311231 AgrOrtholog
BioCyc Gene G2FUF-14763 BioCyc
Ensembl Genes ENSRNOG00000054437 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081077 ENTREZGENE
  ENSRNOT00000081077.3 UniProtKB/TrEMBL
  ENSRNOT00000100608 ENTREZGENE
  ENSRNOT00000100608.2 UniProtKB/TrEMBL
  ENSRNOT00000115747.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  2.60.40.340 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_NFkappaB UniProtKB/TrEMBL
  IPT_TIG_rcpt UniProtKB/TrEMBL
  NF_Rel_dor UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/TrEMBL
  RHD UniProtKB/TrEMBL
  RHD-n_c-Rel UniProtKB/TrEMBL
  RHD_CS UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind_dom_sf UniProtKB/TrEMBL
NCBI Gene 305584 ENTREZGENE
PANTHER PTHR24169 UniProtKB/TrEMBL
  PTHR24169:SF4 UniProtKB/TrEMBL
Pfam RHD UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
PhenoGen Rel PhenoGen
PRINTS NFKBTNSCPFCT UniProtKB/TrEMBL
PROSITE REL_1 UniProtKB/TrEMBL
  REL_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054437 RatGTEx
SMART IPT UniProtKB/TrEMBL
Superfamily-SCOP Ig_E-set UniProtKB/TrEMBL
  P53_like_DNA_bnd UniProtKB/TrEMBL
UniProt A0A8I5XW27 ENTREZGENE
  A0A8I6ABJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LW28_RAT UniProtKB/TrEMBL
  F1M5R1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Rel  REL proto-oncogene, NF-kB subunit  Rel  v-rel avian reticuloendotheliosis viral oncogene homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-23 Rel  v-rel avian reticuloendotheliosis viral oncogene homolog  Rel  v-rel reticuloendotheliosis viral oncogene homolog (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Rel  v-rel reticuloendotheliosis viral oncogene homolog (avian)  Rel  reticuloendotheliosis oncogene   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rel  reticuloendotheliosis oncogene   Rel_predicted  reticuloendotheliosis oncogene (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rel_predicted  reticuloendotheliosis oncogene (predicted)      Symbol and Name status set to approved 70820 APPROVED