Rpl27a (ribosomal protein L27A) - Rat Genome Database

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Gene: Rpl27a (ribosomal protein L27A) Rattus norvegicus
Analyze
Symbol: Rpl27a
Name: ribosomal protein L27A
RGD ID: 1309771
Description: Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL27A (ribosomal protein L27a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 60S ribosomal protein L27a; large ribosomal subunit protein uL15; LOC293418
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rpl27a-ps14  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81172,971,957 - 172,977,591 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21163,539,732 - 163,542,771 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1171,878,344 - 171,881,270 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,064,391 - 179,067,317 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01171,747,016 - 171,749,942 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01174,132,798 - 174,135,816 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1174,132,798 - 174,135,816 (+)Ensemblrn6Rnor6.0
Rnor_5.01181,121,468 - 181,124,486 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41167,115,389 - 167,118,407 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1161,441,403 - 161,444,421 (+)NCBICelera
RGSC_v3.11167,225,785 - 167,228,530 (+)NCBI
Cytogenetic Map1q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dimethoxyphenol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
deoxynivalenol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
eugenol  (EXP,ISO)
folic acid  (ISO)
furfural  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
melphalan  (ISO)
menadione  (ISO)
Mesaconitine  (EXP)
methidathion  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
miconazole  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorodecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
tert-butyl hydroperoxide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, etal., J Biol Chem. 1977 Jun 10;252(11):3961-9.
Additional References at PubMed
PMID:2207170   PMID:2643099   PMID:12962325   PMID:19946888   PMID:22681889   PMID:22871113   PMID:30053369  


Genomics

Comparative Map Data
Rpl27a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81172,971,957 - 172,977,591 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21163,539,732 - 163,542,771 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1171,878,344 - 171,881,270 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,064,391 - 179,067,317 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01171,747,016 - 171,749,942 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01174,132,798 - 174,135,816 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1174,132,798 - 174,135,816 (+)Ensemblrn6Rnor6.0
Rnor_5.01181,121,468 - 181,124,486 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41167,115,389 - 167,118,407 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1161,441,403 - 161,444,421 (+)NCBICelera
RGSC_v3.11167,225,785 - 167,228,530 (+)NCBI
Cytogenetic Map1q33NCBI
RPL27A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38118,682,792 - 8,689,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl118,682,732 - 8,714,759 (+)Ensemblhg38GRCh38
GRCh37118,704,339 - 8,711,419 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36118,660,571 - 8,667,995 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34118,660,914 - 8,663,969NCBI
Celera118,821,627 - 8,829,051 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef118,371,987 - 8,379,412 (+)NCBIHuRef
CHM1_1118,702,911 - 8,710,345 (+)NCBICHM1_1
T2T-CHM13v2.0118,764,546 - 8,771,626 (+)NCBIT2T-CHM13v2.0
Rpl27a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397109,118,354 - 109,121,967 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7109,118,354 - 109,121,574 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm387109,519,195 - 109,522,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7109,519,147 - 109,522,367 (+)Ensemblmm10GRCm38
MGSCv377116,662,709 - 116,665,883 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv367109,310,374 - 109,313,532 (+)NCBIMGSCv36mm8
Celera7109,493,120 - 109,496,304 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.26NCBI
Rpl27a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541424,461,997 - 24,464,828 (+)Ensembl
ChiLan1.0NW_00495541424,461,997 - 24,464,828 (+)NCBIChiLan1.0ChiLan1.0
RPL27A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2911,113,295 - 11,116,519 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,072,026 - 11,075,190 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,807,139 - 8,810,192 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1118,549,367 - 8,552,844 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl118,549,367 - 8,552,845 (+)EnsemblpanPan2panpan1.1
RPL27A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12132,099,792 - 32,102,761 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2132,099,792 - 32,102,754 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2131,668,361 - 31,671,323 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02132,973,385 - 32,976,355 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2132,973,395 - 32,977,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12132,242,588 - 32,245,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02132,408,715 - 32,411,677 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02132,702,260 - 32,705,221 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rpl27a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494753,309,640 - 53,314,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365289,346,592 - 9,348,482 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365289,343,620 - 9,348,935 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL27A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9707,693 - 711,219 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19708,531 - 712,410 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29777,352 - 781,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPL27A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1156,112,593 - 56,115,615 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl156,112,635 - 56,115,639 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038153,801,569 - 153,805,824 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl27a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624766833,503 - 836,185 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624766833,422 - 836,185 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rpl27a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1291,960,614 - 91,962,993 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rpl27a
109 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:245
Count of miRNA genes:167
Interacting mature miRNAs:181
Transcripts:ENSRNOT00000019247
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1131179947176179947Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)1137611478182611478Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1142582336182383862Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1140833106185833106Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1131243790176243790Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1129182274174182274Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1153680016182383862Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1153680016183564652Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1128019551173019551Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1170078537182384005Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436178317588Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
8693608Alc24Alcohol consumption QTL 242.30.74drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1159863716177663210Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436180021436Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1140915717185915717Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat

Markers in Region
AA900726  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q33UniSTS
Cytogenetic Map11q23UniSTS
MARC_1767-1768:991931306:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2189,563,263 - 89,563,500 (+)MAPPERmRatBN7.2
mRatBN7.21163,541,042 - 163,542,183 (+)MAPPERmRatBN7.2
Rnor_6.01174,134,088 - 174,135,228NCBIRnor6.0
Rnor_6.0193,242,254 - 93,242,490NCBIRnor6.0
Rnor_5.0194,354,654 - 94,354,890UniSTSRnor5.0
Rnor_5.01181,122,758 - 181,123,898UniSTSRnor5.0
RGSC_v3.41167,116,679 - 167,117,819UniSTSRGSC3.4
RGSC_v3.4189,339,683 - 89,339,919UniSTSRGSC3.4
Celera183,904,694 - 83,904,930UniSTS
Celera1161,442,693 - 161,443,833UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019247   ⟹   ENSRNOP00000019247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1174,132,798 - 174,135,816 (+)Ensembl
RefSeq Acc Id: NM_001106290   ⟹   NP_001099760
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81172,974,573 - 172,977,591 (+)NCBI
mRatBN7.21163,539,753 - 163,542,771 (+)NCBI
Rnor_6.01174,132,798 - 174,135,816 (+)NCBI
Rnor_5.01181,121,468 - 181,124,486 (+)NCBI
RGSC_v3.41167,115,389 - 167,118,407 (+)RGD
Celera1161,441,403 - 161,444,421 (+)RGD
Sequence:
RefSeq Acc Id: XM_039106965   ⟹   XP_038962893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81172,974,941 - 172,977,051 (+)NCBI
mRatBN7.21163,539,732 - 163,542,233 (+)NCBI
RefSeq Acc Id: XM_063285812   ⟹   XP_063141882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81172,972,009 - 172,977,051 (+)NCBI
RefSeq Acc Id: XM_063285816   ⟹   XP_063141886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81172,971,957 - 172,977,051 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099760 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962893 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141882 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141886 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM17913 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104380
GenBank Protein P18445 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001099760   ⟸   NM_001106290
- UniProtKB: P18445 (UniProtKB/Swiss-Prot),   A6I7W7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019247   ⟸   ENSRNOT00000019247
RefSeq Acc Id: XP_038962893   ⟸   XM_039106965
- Peptide Label: isoform X2
- UniProtKB: A6I7W9 (UniProtKB/TrEMBL),   A6JAD5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141886   ⟸   XM_063285816
- Peptide Label: isoform X1
- UniProtKB: P18445 (UniProtKB/Swiss-Prot),   A6I7W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141882   ⟸   XM_063285812
- Peptide Label: isoform X1
- UniProtKB: P18445 (UniProtKB/Swiss-Prot),   A6I7W7 (UniProtKB/TrEMBL)
Protein Domains
Large ribosomal subunit protein uL15/eL18

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18445-F1-model_v2 AlphaFold P18445 1-148 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690301
Promoter ID:EPDNEW_R826
Type:multiple initiation site
Name:Rpl27a_1
Description:ribosomal protein L27a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01174,132,804 - 174,132,864EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309771 AgrOrtholog
BioCyc Gene G2FUF-57869 BioCyc
Ensembl Genes ENSRNOG00000014214 Ensembl
  ENSRNOG00000088362 ENTREZGENE
Ensembl Transcript ENSRNOT00000145523 ENTREZGENE
Gene3D-CATH 3.100.10.10 UniProtKB/Swiss-Prot
  4.10.990.10 UniProtKB/Swiss-Prot
InterPro L18e/L15P_sf UniProtKB/Swiss-Prot
  Rbsml_prot_L15/27a_N UniProtKB/Swiss-Prot
  Ribosomal_L15 UniProtKB/Swiss-Prot
  Ribosomal_L15_CS UniProtKB/Swiss-Prot
  Ribosomal_L18e/L15P UniProtKB/Swiss-Prot
KEGG Report rno:293418 UniProtKB/Swiss-Prot
NCBI Gene 293418 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L27A UniProtKB/Swiss-Prot
  60S RIBOSOMAL PROTEIN L27A UniProtKB/Swiss-Prot
Pfam Ribosomal_L27A UniProtKB/Swiss-Prot
PhenoGen Rpl27a PhenoGen
PROSITE RIBOSOMAL_L15 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014214 RatGTEx
  ENSRNOG00000088362 RatGTEx
Superfamily-SCOP SSF52080 UniProtKB/Swiss-Prot
UniProt A6I7W7 ENTREZGENE, UniProtKB/TrEMBL
  A6I7W9 ENTREZGENE, UniProtKB/TrEMBL
  A6JAD5 ENTREZGENE, UniProtKB/TrEMBL
  P18445 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-07 Rpl27a  ribosomal protein L27A  Rpl27a  ribosomal protein L27a  Name changed 629549 APPROVED
2008-04-30 Rpl27a  ribosomal protein L27a   Rpl27a_predicted  ribosomal protein L27a (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rpl27a_predicted  ribosomal protein L27a (predicted)      Symbol and Name status set to approved 70820 APPROVED