Setd3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase) - Rat Genome Database

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Gene: Setd3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase) Rattus norvegicus
Analyze
Symbol: Setd3
Name: SET domain containing 3, actin N3(tau)-histidine methyltransferase
RGD ID: 1309550
Description: Enables protein-L-histidine N-tele-methyltransferase activity. Involved in actin modification and peptidyl-histidine methylation. Predicted to be located in chromatin and cytoplasm. Orthologous to human SETD3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-histidine N-methyltransferase; histone-lysine N-methyltransferase setd3; histone-lysine N-methyltransferase setd3-like; LOC100910833; LOC299295; protein-L-histidine N-tele-methyltransferase; RGD1309550; SET domain containing 3; SET domain containing 3, actin histidine methyltransferase; SET domain-containing protein 3; similar to hypothetical protein D12Ertd771e
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Setd3-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,787,478 - 132,854,421 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6132,787,495 - 132,854,421 (-)EnsemblGRCr8
mRatBN7.26127,023,058 - 127,090,020 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,023,058 - 127,090,008 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6127,147,450 - 127,214,376 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,442,494 - 127,509,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,800,688 - 126,867,637 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,023,128 - 132,090,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)Ensemblrn6Rnor6.0
Rnor_5.06141,193,508 - 141,260,420 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46132,479,553 - 132,546,414 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6124,582,489 - 124,649,275 (-)NCBICelera
RGSC_v3.16132,455,160 - 132,552,700 (-)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO)
cytoplasm  (IEA,ISO,ISS)
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. SETD3 protein is the actin-specific histidine N-methyltransferase. Kwiatkowski S, etal., Elife. 2018 Dec 11;7. pii: 37921. doi: 10.7554/eLife.37921.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21832073   PMID:29950684   PMID:30626964   PMID:30785395   PMID:34218417  


Genomics

Comparative Map Data
Setd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,787,478 - 132,854,421 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6132,787,495 - 132,854,421 (-)EnsemblGRCr8
mRatBN7.26127,023,058 - 127,090,020 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,023,058 - 127,090,008 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6127,147,450 - 127,214,376 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,442,494 - 127,509,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,800,688 - 126,867,637 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,023,128 - 132,090,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)Ensemblrn6Rnor6.0
Rnor_5.06141,193,508 - 141,260,420 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46132,479,553 - 132,546,414 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6124,582,489 - 124,649,275 (-)NCBICelera
RGSC_v3.16132,455,160 - 132,552,700 (-)NCBI
Cytogenetic Map6q32NCBI
SETD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,397,748 - 99,486,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,395,061 - 99,480,927 (-)Ensemblhg38GRCh38
GRCh371499,864,085 - 99,947,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361498,933,836 - 99,016,979 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1479,918,981 - 80,002,111 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,047,465 - 80,130,640 (-)NCBIHuRef
CHM1_11499,801,849 - 99,884,990 (-)NCBICHM1_1
T2T-CHM13v2.01493,629,309 - 93,718,026 (-)NCBIT2T-CHM13v2.0
Setd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,072,690 - 108,145,616 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,072,690 - 108,145,573 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812108,106,431 - 108,179,345 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,106,431 - 108,179,314 (-)Ensemblmm10GRCm38
MGSCv3712109,344,641 - 109,417,494 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612108,554,247 - 108,627,070 (-)NCBIMGSCv36mm8
Celera12109,343,892 - 109,402,354 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.23NCBI
Setd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543820,754,539 - 20,826,700 (-)Ensembl
ChiLan1.0NW_00495543820,754,593 - 20,826,570 (-)NCBIChiLan1.0ChiLan1.0
SETD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,552,654 - 100,635,474 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11499,769,148 - 99,851,960 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,022,123 - 80,104,935 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,344,422 - 99,427,036 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1499,343,164 - 99,426,486 (-)EnsemblpanPan2panpan1.1
SETD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,821,394 - 67,899,814 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,821,968 - 67,886,557 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha867,344,686 - 67,424,084 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0868,108,090 - 68,187,690 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,108,102 - 68,187,606 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,769,231 - 67,848,727 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,835,703 - 67,915,160 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,232,725 - 68,312,327 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Setd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,814,451 - 6,872,970 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,209,360 - 3,267,937 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,209,498 - 3,268,030 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SETD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,412,545 - 120,486,686 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17120,412,545 - 120,486,687 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27127,972,348 - 128,046,483 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SETD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,346,119 - 77,435,978 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,345,205 - 77,435,896 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605364,486,997 - 64,572,516 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Setd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,393,188 - 4,469,224 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247344,392,627 - 4,468,961 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Setd3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17125,784,620 - 125,850,699 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Setd3
2396 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:430
Count of miRNA genes:228
Interacting mature miRNAs:272
Transcripts:ENSRNOT00000009120, ENSRNOT00000044312
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6131392689143944780Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
RH128412  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,210 - 127,023,426 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,281 - 132,023,496NCBIRnor6.0
Rnor_5.06141,193,661 - 141,193,876UniSTSRnor5.0
RGSC_v3.46132,479,706 - 132,479,921UniSTSRGSC3.4
Celera6124,582,642 - 124,582,857UniSTS
RH 3.4 Map6791.7UniSTS
Cytogenetic Map6q32UniSTS
D12Ertd771e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,106 - 127,023,376 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,177 - 132,023,446NCBIRnor6.0
Rnor_5.06141,193,557 - 141,193,826UniSTSRnor5.0
RGSC_v3.46132,479,602 - 132,479,871UniSTSRGSC3.4
Celera6124,582,538 - 124,582,807UniSTS
Cytogenetic Map6q32UniSTS
RH140597  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,841 - 127,024,045 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,912 - 132,024,115NCBIRnor6.0
Rnor_5.06141,194,292 - 141,194,495UniSTSRnor5.0
RGSC_v3.46132,480,337 - 132,480,540UniSTSRGSC3.4
Celera6124,583,273 - 124,583,476UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009120   ⟹   ENSRNOP00000009121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6132,787,495 - 132,854,421 (-)Ensembl
mRatBN7.2 Ensembl6127,023,075 - 127,090,008 (-)Ensembl
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000057179   ⟹   ENSRNOP00000054006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6132,787,495 - 132,840,231 (-)Ensembl
mRatBN7.2 Ensembl6127,023,058 - 127,089,941 (-)Ensembl
Rnor_6.0 Ensembl6131,602,413 - 131,648,661 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094185   ⟹   ENSRNOP00000084001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,023,058 - 127,072,479 (-)Ensembl
RefSeq Acc Id: NM_001346470   ⟹   NP_001333399
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,854,421 (-)NCBI
mRatBN7.26127,023,058 - 127,090,008 (-)NCBI
RefSeq Acc Id: XM_063261778   ⟹   XP_063117848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,837,292 (-)NCBI
RefSeq Acc Id: XM_063261779   ⟹   XP_063117849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,235 (-)NCBI
RefSeq Acc Id: XM_063261780   ⟹   XP_063117850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,137 (-)NCBI
RefSeq Acc Id: XM_063261781   ⟹   XP_063117851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,175 (-)NCBI
Ensembl Acc Id: ENSRNOP00000009121   ⟸   ENSRNOT00000009120
RefSeq Acc Id: NP_001333399   ⟸   NM_001346470
- UniProtKB: Q5FWY6 (UniProtKB/Swiss-Prot),   G3V6U9 (UniProtKB/TrEMBL),   A6KBF2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000054006   ⟸   ENSRNOT00000057179
Ensembl Acc Id: ENSRNOP00000084001   ⟸   ENSRNOT00000094185
RefSeq Acc Id: XP_063117849   ⟸   XM_063261779
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A126 (UniProtKB/TrEMBL),   A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117851   ⟸   XM_063261781
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A126 (UniProtKB/TrEMBL),   A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117850   ⟸   XM_063261780
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A126 (UniProtKB/TrEMBL),   A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117848   ⟸   XM_063261778
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A126 (UniProtKB/TrEMBL),   D4A7S1 (UniProtKB/TrEMBL)
Protein Domains
SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A7S1-F1-model_v2 AlphaFold D4A7S1 1-381 view protein structure
AF-G3V6U9-F1-model_v2 AlphaFold G3V6U9 1-596 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309550 AgrOrtholog
BioCyc Gene G2FUF-36310 BioCyc
Ensembl Genes ENSRNOG00000006587 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000046275 Ensembl
Ensembl Transcript ENSRNOT00000009120 ENTREZGENE
  ENSRNOT00000009120.9 UniProtKB/Swiss-Prot
  ENSRNOT00000057179 ENTREZGENE
Gene3D-CATH 3.90.1420.10 UniProtKB/Swiss-Prot
  set domain protein methyltransferase, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7311656 IMAGE-MGC_LOAD
InterPro Rubisco_LSMT_subst-bd UniProtKB/Swiss-Prot
  Rubisco_LSMT_subst-bd_sf UniProtKB/Swiss-Prot
  SET_dom UniProtKB/Swiss-Prot
  SET_dom_sf UniProtKB/Swiss-Prot
  SETD3 UniProtKB/Swiss-Prot
  SETD3_SET UniProtKB/Swiss-Prot
  SETD3_SETD6_MTase UniProtKB/Swiss-Prot
KEGG Report rno:299295 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105804 IMAGE-MGC_LOAD
NCBI Gene 299295 ENTREZGENE
PANTHER ACTIN-HISTIDINE N-METHYLTRANSFERASE UniProtKB/Swiss-Prot
  UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam Rubis-subs-bind UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
PhenoGen Setd3 PhenoGen
PROSITE SAM_MT43_SETD3 UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006587 RatGTEx
  ENSRNOG00000046275 RatGTEx
Superfamily-SCOP SSF81822 UniProtKB/Swiss-Prot
  SSF82199 UniProtKB/Swiss-Prot
UniProt A0A8I6A126 ENTREZGENE
  A6KBF2 ENTREZGENE, UniProtKB/TrEMBL
  A6KBF4 ENTREZGENE, UniProtKB/TrEMBL
  D4A7S1 ENTREZGENE, UniProtKB/TrEMBL
  G3V6U9 ENTREZGENE
  Q5FWY6 ENTREZGENE
  SETD3_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5FWY6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-09 Setd3  SET domain containing 3, actin N3(tau)-histidine methyltransferase  Setd3  SET domain containing 3, actin histidine methyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Setd3  SET domain containing 3, actin histidine methyltransferase  LOC100910833  histone-lysine N-methyltransferase setd3-like  Data merged from RGD:6496142 737654 PROVISIONAL
2019-01-04 Setd3  SET domain containing 3, actin histidine methyltransferase  Setd3  SET domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910833  histone-lysine N-methyltransferase setd3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-26 Setd3  SET domain containing 3  RGD1309550  similar to hypothetical protein D12Ertd771e  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309550  similar to hypothetical protein D12Ertd771e  RGD1309550_predicted  similar to hypothetical protein D12Ertd771e (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309550_predicted  similar to hypothetical protein D12Ertd771e (predicted)  LOC299295_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299295_predicted  similar to hypothetical protein D12Ertd771e (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL