Lrfn5 (leucine rich repeat and fibronectin type III domain containing 5) - Rat Genome Database

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Gene: Lrfn5 (leucine rich repeat and fibronectin type III domain containing 5) Rattus norvegicus
Analyze
Symbol: Lrfn5
Name: leucine rich repeat and fibronectin type III domain containing 5
RGD ID: 1309357
Description: Involved in synaptic membrane adhesion. Is active in postsynaptic density membrane. Orthologous to human LRFN5 (leucine rich repeat and fibronectin type III domain containing 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: leucine-rich repeat and fibronectin type-III domain-containing protein 5; LOC314164
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8685,201,465 - 85,557,872 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl685,201,364 - 85,558,539 (+)EnsemblGRCr8
mRatBN7.2679,466,403 - 79,822,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl679,467,961 - 79,822,815 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx679,870,429 - 80,226,228 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0680,169,774 - 80,525,588 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0679,605,241 - 79,960,964 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0683,082,593 - 83,438,601 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl683,083,740 - 83,438,601 (+)Ensemblrn6Rnor6.0
Rnor_5.0692,601,831 - 92,958,936 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4682,482,116 - 82,656,279 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera678,123,282 - 78,474,424 (+)NCBICelera
RGSC_v3.1682,889,667 - 82,906,372 (+)NCBI
Cytogenetic Map6q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IBA,IEA,ISO)
GABA-ergic synapse  (IBA,IEA,ISO)
glutamatergic synapse  (IBA,IEA,ISO)
membrane  (IEA)
postsynaptic density membrane  (IBA,IDA,IEA,IEP)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development. Choi Y, etal., Sci Rep. 2016 May 26;6:26676. doi: 10.1038/srep26676.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. Mah W, etal., J Neurosci. 2010 Apr 21;30(16):5559-68. doi: 10.1523/JNEUROSCI.4839-09.2010.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16828986   PMID:27152329  


Genomics

Comparative Map Data
Lrfn5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8685,201,465 - 85,557,872 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl685,201,364 - 85,558,539 (+)EnsemblGRCr8
mRatBN7.2679,466,403 - 79,822,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl679,467,961 - 79,822,815 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx679,870,429 - 80,226,228 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0680,169,774 - 80,525,588 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0679,605,241 - 79,960,964 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0683,082,593 - 83,438,601 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl683,083,740 - 83,438,601 (+)Ensemblrn6Rnor6.0
Rnor_5.0692,601,831 - 92,958,936 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4682,482,116 - 82,656,279 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera678,123,282 - 78,474,424 (+)NCBICelera
RGSC_v3.1682,889,667 - 82,906,372 (+)NCBI
Cytogenetic Map6q23NCBI
LRFN5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381441,606,876 - 41,904,549 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1441,606,733 - 41,904,549 (+)Ensemblhg38GRCh38
GRCh371442,076,079 - 42,373,752 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361441,147,090 - 41,443,499 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341441,147,093 - 41,443,498NCBI
Celera1421,937,439 - 22,234,297 (+)NCBICelera
Cytogenetic Map14q21.1NCBI
HuRef1422,187,067 - 22,483,854 (+)NCBIHuRef
CHM1_11442,014,900 - 42,311,898 (+)NCBICHM1_1
T2T-CHM13v2.01435,797,646 - 36,095,321 (+)NCBIT2T-CHM13v2.0
Lrfn5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391261,569,356 - 61,913,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1261,569,936 - 61,905,128 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381261,522,851 - 61,857,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1261,523,150 - 61,858,342 (+)Ensemblmm10GRCm38
MGSCv371262,625,619 - 62,946,245 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361262,442,645 - 62,763,271 (+)NCBIMGSCv36mm8
Celera1262,712,498 - 63,024,396 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1226.43NCBI
Lrfn5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540919,710,305 - 19,856,123 (-)Ensembl
ChiLan1.0NW_00495540919,710,527 - 19,969,984 (-)NCBIChiLan1.0ChiLan1.0
LRFN5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21542,740,303 - 43,035,903 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11441,956,817 - 42,252,417 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01422,185,289 - 22,480,641 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11440,519,143 - 40,814,212 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1440,676,278 - 40,814,212 (+)EnsemblpanPan2panpan1.1
LRFN5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1819,365,786 - 19,602,551 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl819,367,570 - 19,602,185 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha819,177,231 - 19,413,096 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0819,508,003 - 19,744,373 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl819,509,804 - 19,745,878 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1819,183,646 - 19,420,029 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0819,256,859 - 19,493,267 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0819,517,360 - 19,753,738 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lrfn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864051,402,747 - 51,649,903 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649415,138,854 - 15,156,555 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649414,908,783 - 15,155,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRFN5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1171,906,198 - 172,177,720 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11171,906,130 - 172,177,726 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21191,439,600 - 191,710,127 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRFN5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12418,421,057 - 18,712,096 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2418,568,568 - 18,712,609 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660537,563,895 - 7,851,872 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrfn5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481311,049,888 - 11,196,095 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462481310,930,009 - 11,196,036 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lrfn5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1775,483,317 - 75,500,026 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lrfn5
1699 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:25
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000007600
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
D6Got310  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8685,251,070 - 85,251,245 (+)Marker Load Pipeline
mRatBN7.2679,516,001 - 79,516,176 (+)MAPPERmRatBN7.2
Rnor_6.0683,131,842 - 83,132,016NCBIRnor6.0
Rnor_5.0692,651,058 - 92,651,232UniSTSRnor5.0
RGSC_v3.4682,607,395 - 82,607,569UniSTSRGSC3.4
Celera678,171,147 - 78,171,321UniSTS
Cytogenetic Map6q23UniSTS
D6Got304  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0683,101,929 - 83,102,019NCBIRnor6.0
Rnor_5.0692,621,145 - 92,621,235UniSTSRnor5.0
RGSC_v3.4682,637,423 - 82,637,513UniSTSRGSC3.4
Celera678,141,342 - 78,141,436UniSTS
Cytogenetic Map6q23UniSTS
RH136499  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2679,637,593 - 79,637,802 (+)MAPPERmRatBN7.2
mRatBN7.21346,731,287 - 46,731,496 (+)MAPPERmRatBN7.2
Rnor_6.01352,124,812 - 52,125,020NCBIRnor6.0
Rnor_6.0683,252,719 - 83,252,927NCBIRnor6.0
Rnor_5.01357,174,343 - 57,174,551UniSTSRnor5.0
Rnor_5.0692,772,158 - 92,772,366UniSTSRnor5.0
RGSC_v3.4682,484,770 - 82,484,978UniSTSRGSC3.4
RGSC_v3.41348,297,687 - 48,297,895UniSTSRGSC3.4
Celera1347,051,865 - 47,052,073UniSTS
Celera678,292,310 - 78,292,518UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map6q23UniSTS
Lrfn5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2679,806,365 - 79,807,251 (+)MAPPERmRatBN7.2
Rnor_6.0683,422,152 - 83,423,037NCBIRnor6.0
Rnor_5.0692,942,487 - 92,943,372UniSTSRnor5.0
RGSC_v3.4682,886,504 - 82,887,389UniSTSRGSC3.4
Celera678,457,967 - 78,458,852UniSTS
Cytogenetic Map6q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 1 46 130 44 42 23 13 23 6 142 75 114 35 75 19 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000007600   ⟹   ENSRNOP00000007600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl685,201,364 - 85,557,866 (+)Ensembl
mRatBN7.2 Ensembl679,467,961 - 79,822,815 (+)Ensembl
Rnor_6.0 Ensembl683,083,740 - 83,438,601 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084258   ⟹   ENSRNOP00000073272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl683,421,882 - 83,432,133 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148545   ⟹   ENSRNOP00000103257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl685,201,364 - 85,558,539 (+)Ensembl
RefSeq Acc Id: NM_001108024   ⟹   NP_001101494
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8685,203,026 - 85,557,866 (+)NCBI
mRatBN7.2679,467,961 - 79,822,815 (+)NCBI
Rnor_6.0683,083,740 - 83,438,601 (+)NCBI
Rnor_5.0692,601,831 - 92,958,936 (+)NCBI
RGSC_v3.4682,482,116 - 82,656,279 (-)RGD
Celera678,123,282 - 78,474,424 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112240   ⟹   XP_038968168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8685,201,469 - 85,557,872 (+)NCBI
mRatBN7.2679,466,412 - 79,822,821 (+)NCBI
RefSeq Acc Id: XM_039112241   ⟹   XP_038968169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8685,201,469 - 85,557,872 (+)NCBI
mRatBN7.2679,466,412 - 79,822,821 (+)NCBI
RefSeq Acc Id: XR_001838166
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8685,201,465 - 85,545,157 (+)NCBI
mRatBN7.2679,466,403 - 79,810,106 (+)NCBI
Rnor_6.0683,082,593 - 83,425,845 (+)NCBI
Sequence:
RefSeq Acc Id: XR_593049
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8685,201,465 - 85,545,161 (+)NCBI
mRatBN7.2679,466,403 - 79,810,102 (+)NCBI
Rnor_6.0683,082,593 - 83,425,840 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001101494 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968168 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968169 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A1J9 (Get FASTA)   NCBI Sequence Viewer  
  EDM03478 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007600
  ENSRNOP00000007600.6
  ENSRNOP00000103257
RefSeq Acc Id: NP_001101494   ⟸   NM_001108024
- Peptide Label: precursor
- UniProtKB: D4A1J9 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007600   ⟸   ENSRNOT00000007600
Ensembl Acc Id: ENSRNOP00000073272   ⟸   ENSRNOT00000084258
RefSeq Acc Id: XP_038968169   ⟸   XM_039112241
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038968168   ⟸   XM_039112240
- Peptide Label: isoform X1
- UniProtKB: D4A1J9 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000103257   ⟸   ENSRNOT00000148545
Protein Domains
Fibronectin type-III   Ig-like   LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1J9-F1-model_v2 AlphaFold D4A1J9 1-719 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694620
Promoter ID:EPDNEW_R5144
Type:single initiation site
Name:Lrfn5_1
Description:leucine rich repeat and fibronectin type III domain containing5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0683,083,834 - 83,083,894EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309357 AgrOrtholog
BioCyc Gene G2FUF-37355 BioCyc
Ensembl Genes ENSRNOG00000005550 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007600 ENTREZGENE
  ENSRNOT00000007600.8 UniProtKB/Swiss-Prot
  ENSRNOT00000148545 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
InterPro FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot
  LRFN UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:314164 UniProtKB/Swiss-Prot
NCBI Gene 314164 ENTREZGENE
PANTHER PTHR45842:SF10 UniProtKB/Swiss-Prot
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  LRR_8 UniProtKB/Swiss-Prot
PhenoGen Lrfn5 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  LRR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005550 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  LRR_TYP UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
  SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0ABK0L2V0_RAT UniProtKB/TrEMBL
  D4A1J9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Lrfn5  leucine rich repeat and fibronectin type III domain containing 5  LOC100360181  leucine rich repeat and fibronectin type III domain containing 5  Data merged from RGD:2322668 1643240 APPROVED
2010-05-06 LOC100360181  leucine rich repeat and fibronectin type III domain containing 5      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Lrfn5  leucine rich repeat and fibronectin type III domain containing 5   Lrfn5_predicted  leucine rich repeat and fibronectin type III domain containing 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lrfn5_predicted  leucine rich repeat and fibronectin type III domain containing 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED