Nmnat3 (nicotinamide nucleotide adenylyltransferase 3) - Rat Genome Database

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Gene: Nmnat3 (nicotinamide nucleotide adenylyltransferase 3) Rattus norvegicus
Analyze
Symbol: Nmnat3
Name: nicotinamide nucleotide adenylyltransferase 3
RGD ID: 1309140
Description: Predicted to enable nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Involved in response to tumor necrosis factor. Located in axon and neuronal cell body. Used to study glaucoma. Orthologous to human NMNAT3 (nicotinamide nucleotide adenylyltransferase 3); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; INTERACTS WITH 2,6-dinitrotoluene; acetamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363118; nicotinamide mononucleotide adenylyltransferase 3; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,771,124 - 107,888,528 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8107,771,509 - 107,900,016 (+)EnsemblGRCr8
mRatBN7.2898,892,168 - 99,003,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl898,873,398 - 99,020,645 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8104,561,145 - 104,672,788 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,760,392 - 102,872,044 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,602,906 - 100,714,552 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,317,038 - 106,429,535 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)Ensemblrn6Rnor6.0
Rnor_5.08105,760,369 - 105,871,374 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48103,472,426 - 103,584,246 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera898,304,722 - 98,415,332 (+)NCBICelera
RGSC_v3.18103,491,880 - 103,603,693 (+)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IDA)
mitochondrial matrix  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)
neuronal cell body  (IDA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Houtkooper RH, etal., Endocr Rev. 2010 Apr;31(2):194-223. doi: 10.1210/er.2009-0026. Epub 2009 Dec 9.
3. Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration. Kitaoka Y, etal., Cell Death Dis. 2013 Oct 17;4:e860. doi: 10.1038/cddis.2013.391.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16118205   PMID:16914673   PMID:27423420  


Genomics

Comparative Map Data
Nmnat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,771,124 - 107,888,528 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8107,771,509 - 107,900,016 (+)EnsemblGRCr8
mRatBN7.2898,892,168 - 99,003,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl898,873,398 - 99,020,645 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8104,561,145 - 104,672,788 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,760,392 - 102,872,044 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,602,906 - 100,714,552 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,317,038 - 106,429,535 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)Ensemblrn6Rnor6.0
Rnor_5.08105,760,369 - 105,871,374 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48103,472,426 - 103,584,246 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera898,304,722 - 98,415,332 (+)NCBICelera
RGSC_v3.18103,491,880 - 103,603,693 (+)NCBI
Cytogenetic Map8q31NCBI
NMNAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,560,180 - 139,678,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,558,709 - 139,678,017 (-)Ensemblhg38GRCh38
GRCh373139,279,022 - 139,396,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,761,723 - 140,879,530 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343140,761,731 - 140,879,538NCBI
Celera3137,701,933 - 137,819,739 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,654,467 - 136,772,328 (-)NCBIHuRef
CHM1_13139,242,474 - 139,360,320 (-)NCBICHM1_1
T2T-CHM13v2.03142,307,606 - 142,425,486 (-)NCBIT2T-CHM13v2.0
Nmnat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,169,487 - 98,302,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,169,488 - 98,302,491 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38998,287,433 - 98,420,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,287,435 - 98,420,438 (+)Ensemblmm10GRCm38
MGSCv37998,197,002 - 98,311,847 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36998,105,935 - 98,220,780 (+)NCBIMGSCv36mm8
Celera997,850,409 - 97,963,936 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.35NCBI
Nmnat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555085,913,898 - 6,022,128 (+)Ensembl
ChiLan1.0NW_0049555085,909,808 - 6,024,301 (+)NCBIChiLan1.0ChiLan1.0
NMNAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,472,086 - 137,592,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,476,826 - 137,597,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,594,825 - 136,715,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,196,529 - 144,313,658 (-)NCBIPanPan1.1PanPan1.1panPan2
NMNAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,714,162 - 35,829,150 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,714,933 - 35,829,049 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2335,701,815 - 35,816,030 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02336,250,931 - 36,365,957 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,250,934 - 36,366,221 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,933,008 - 36,047,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02336,006,480 - 36,121,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,249,065 - 36,363,588 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nmnat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,886,743 - 75,026,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,636,380 - 1,766,306 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,653,243 - 1,766,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,429,639 - 80,556,790 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21388,294,211 - 88,321,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11550,880,146 - 50,990,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1550,880,235 - 50,991,281 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604123,853,934 - 23,964,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmnat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473016,158,485 - 16,231,670 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473016,151,185 - 16,289,260 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nmnat3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1889,774,877 - 89,787,040 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nmnat3
708 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:110
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000018411
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
D8Rat15  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,847,991 - 107,848,139 (+)Marker Load Pipeline
mRatBN7.2898,968,617 - 98,968,765 (+)MAPPERmRatBN7.2
Rnor_6.08106,394,231 - 106,394,378NCBIRnor6.0
Rnor_5.08105,836,600 - 105,836,747UniSTSRnor5.0
RGSC_v3.48103,548,728 - 103,548,876RGDRGSC3.4
RGSC_v3.48103,548,729 - 103,548,876UniSTSRGSC3.4
Celera898,380,264 - 98,380,411UniSTS
RGSC_v3.18103,568,183 - 103,568,331RGD
RH 2.0 Map8844.1RGD
SHRSP x BN Map860.66RGD
Cytogenetic Map8q31UniSTS
D8Got322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2898,951,861 - 98,952,055 (+)MAPPERmRatBN7.2
Rnor_6.08106,377,475 - 106,377,668NCBIRnor6.0
Rnor_5.08105,819,844 - 105,820,037UniSTSRnor5.0
RGSC_v3.48103,531,973 - 103,532,166UniSTSRGSC3.4
Celera898,363,508 - 98,363,701UniSTS
Cytogenetic Map8q31UniSTS
RH139250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2899,003,563 - 99,003,697 (+)MAPPERmRatBN7.2
Rnor_6.08106,429,187 - 106,429,320NCBIRnor6.0
Rnor_5.08105,871,026 - 105,871,159UniSTSRnor5.0
RGSC_v3.48103,583,898 - 103,584,031UniSTSRGSC3.4
Celera898,414,984 - 98,415,117UniSTS
RH 3.4 Map81051.99UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018411   ⟹   ENSRNOP00000018411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8107,771,509 - 107,883,275 (+)Ensembl
mRatBN7.2 Ensembl898,892,471 - 99,003,904 (+)Ensembl
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097766   ⟹   ENSRNOP00000079845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl898,873,398 - 99,003,904 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114276   ⟹   ENSRNOP00000079147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8107,771,509 - 107,900,016 (+)Ensembl
mRatBN7.2 Ensembl898,892,471 - 99,020,645 (+)Ensembl
RefSeq Acc Id: NM_001395701   ⟹   NP_001382630
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,613 - 107,883,283 (+)NCBI
mRatBN7.2898,892,229 - 99,003,912 (+)NCBI
RefSeq Acc Id: NM_001395702   ⟹   NP_001382631
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,613 - 107,883,283 (+)NCBI
mRatBN7.2898,892,229 - 99,003,912 (+)NCBI
RefSeq Acc Id: XM_039081772   ⟹   XP_038937700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
mRatBN7.2898,892,170 - 99,003,912 (+)NCBI
RefSeq Acc Id: XM_039081774   ⟹   XP_038937702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,824,844 - 107,888,528 (+)NCBI
mRatBN7.2898,945,463 - 99,003,912 (+)NCBI
RefSeq Acc Id: XM_039081775   ⟹   XP_038937703
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
mRatBN7.2898,892,168 - 99,002,735 (+)NCBI
RefSeq Acc Id: XM_063265801   ⟹   XP_063121871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
RefSeq Acc Id: XM_063265802   ⟹   XP_063121872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
RefSeq Acc Id: XM_063265803   ⟹   XP_063121873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
RefSeq Acc Id: XM_063265804   ⟹   XP_063121874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
RefSeq Acc Id: XM_063265805   ⟹   XP_063121875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,771,124 - 107,888,528 (+)NCBI
Ensembl Acc Id: ENSRNOP00000018411   ⟸   ENSRNOT00000018411
RefSeq Acc Id: XP_038937703   ⟸   XM_039081775
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038937700   ⟸   XM_039081772
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038937702   ⟸   XM_039081774
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000079845   ⟸   ENSRNOT00000097766
Ensembl Acc Id: ENSRNOP00000079147   ⟸   ENSRNOT00000114276
RefSeq Acc Id: NP_001382630   ⟸   NM_001395701
- UniProtKB: F7F588 (UniProtKB/TrEMBL),   A6I2B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382631   ⟸   NM_001395702
- UniProtKB: F7F588 (UniProtKB/TrEMBL),   A6I2B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121871   ⟸   XM_063265801
- Peptide Label: isoform X1
- UniProtKB: A6I2B1 (UniProtKB/TrEMBL),   F7F588 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121872   ⟸   XM_063265802
- Peptide Label: isoform X1
- UniProtKB: A6I2B1 (UniProtKB/TrEMBL),   F7F588 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121875   ⟸   XM_063265805
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063121874   ⟸   XM_063265804
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063121873   ⟸   XM_063265803
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNV6 (UniProtKB/TrEMBL)
Protein Domains
Cytidyltransferase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7F588-F1-model_v2 AlphaFold F7F588 1-245 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696199
Promoter ID:EPDNEW_R6724
Type:initiation region
Name:Nmnat3_2
Description:nicotinamide nucleotide adenylyltransferase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6725  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08106,317,135 - 106,317,195EPDNEW
RGD ID:13696200
Promoter ID:EPDNEW_R6725
Type:multiple initiation site
Name:Nmnat3_1
Description:nicotinamide nucleotide adenylyltransferase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6724  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08106,317,369 - 106,317,429EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309140 AgrOrtholog
BioCyc Gene G2FUF-29420 BioCyc
BioCyc Pathway PWY-5653 [NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde] BioCyc
  PWY3O-4107 [NAD salvage pathway V (PNC V cycle)] BioCyc
BioCyc Pathway Image PWY-5653 BioCyc
  PWY3O-4107 BioCyc
Ensembl Genes ENSRNOG00000013585 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018411 ENTREZGENE
  ENSRNOT00000018411.8 UniProtKB/TrEMBL
  ENSRNOT00000114276.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7191168 IMAGE-MGC_LOAD
InterPro Cyt_trans-like UniProtKB/TrEMBL
  Euk_NMN_adenylyltrnsfrase UniProtKB/TrEMBL
  NAMN_adtrnsfrase UniProtKB/TrEMBL
  NMNAT_euk UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
MGC_CLONE MGC:94624 IMAGE-MGC_LOAD
NCBI Gene 363118 ENTREZGENE
PANTHER NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE UniProtKB/TrEMBL
  NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 UniProtKB/TrEMBL
Pfam CTP_transf_2 UniProtKB/TrEMBL
PhenoGen Nmnat3 PhenoGen
RatGTEx ENSRNOG00000013585 RatGTEx
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
UniProt A0A8I5ZM75_RAT UniProtKB/TrEMBL
  A0A8I5ZNV6 ENTREZGENE
  A6I2B1 ENTREZGENE, UniProtKB/TrEMBL
  F7F588 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIF7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Nmnat3  nicotinamide nucleotide adenylyltransferase 3  Nmnat3_predicted  nicotinamide nucleotide adenylyltransferase 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nmnat3_predicted  nicotinamide nucleotide adenylyltransferase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED