Sox6 (SRY-box transcription factor 6) - Rat Genome Database

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Gene: Sox6 (SRY-box transcription factor 6) Rattus norvegicus
Analyze
Symbol: Sox6
Name: SRY-box transcription factor 6
RGD ID: 1309000
Description: Enables cis-regulatory region sequence-specific DNA binding activity. Involved in astrocyte differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human SOX6 (SRY-box transcription factor 6); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC102549121; SRY (sex determining region Y)-box 6; SRY box 6; SRY-box containing gene 6; transcription factor SOX-6; uncharacterized LOC102549121
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,157,678 - 179,769,243 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1179,163,566 - 179,711,727 (-)EnsemblGRCr8
mRatBN7.21169,723,306 - 170,334,846 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,729,194 - 170,277,386 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1178,052,031 - 178,553,600 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,238,507 - 185,740,114 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01177,945,239 - 178,446,677 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01185,631,702 - 186,186,192 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,673,177 - 186,182,829 (+)Ensemblrn6Rnor6.0
Rnor_5.01192,644,288 - 193,155,831 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41173,556,966 - 174,069,437 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,560,079 - 168,058,656 (-)NCBICelera
RGSC_v3.11173,696,212 - 174,208,683 (-)NCBI
Cytogenetic Map1q35NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dibutyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glucose  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
mercury dibromide  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte differentiation  (IMP)
brain development  (IEA,ISO,ISS)
cardiac muscle cell differentiation  (ISO)
cartilage condensation  (ISO,ISS)
cartilage development  (ISO,ISS)
cell differentiation  (IEA)
cell fate commitment  (IBA,ISO)
cell morphogenesis  (ISO)
cellular response to transforming growth factor beta stimulus  (IEA,ISO)
central nervous system development  (IBA)
chondrocyte differentiation  (ISO,ISS)
erythrocyte development  (ISO)
erythrocyte differentiation  (ISO)
gene expression  (ISO)
hemopoiesis  (ISO)
in utero embryonic development  (ISO)
muscle cell differentiation  (ISO)
negative regulation of cardiac muscle cell differentiation  (IEA,ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
obsolete regulation of DNA-binding transcription factor activity  (ISO)
oligodendrocyte cell fate specification  (ISO)
oligodendrocyte differentiation  (ISO)
positive regulation of cartilage development  (IEA,ISO)
positive regulation of chondrocyte differentiation  (IBA,IEA,ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of mesenchymal stem cell differentiation  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
post-embryonic development  (ISO)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of gene expression  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
spinal cord oligodendrocyte cell differentiation  (ISO)

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Trbp regulates heart function through microRNA-mediated Sox6 repression. Ding J, etal., Nat Genet. 2015 Jul;47(7):776-83. doi: 10.1038/ng.3324. Epub 2015 Jun 1.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. Hagiwara N, etal., Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4180-5.
5. SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. Iguchi H, etal., J Biol Chem. 2005 Nov 11;280(45):37669-80. Epub 2005 Sep 7.
6. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Liu CF and Lefebvre V, Nucleic Acids Res. 2015 Sep 30;43(17):8183-203. doi: 10.1093/nar/gkv688. Epub 2015 Jul 6.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Quantitative analysis of gene expression in living adult neural stem cells by gene trapping. Scheel JR, etal., Nat Methods. 2005 May;2(5):363-70. Epub 2005 Apr 21.
12. MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction. Tony H, etal., Mediators Inflamm. 2015;2015:479123. doi: 10.1155/2015/479123. Epub 2015 Nov 25.
13. Expression of a transcriptional factor, SOX6, in human gliomas. Ueda R, etal., Brain Tumor Pathol. 2004;21(1):35-8.
Additional References at PubMed
PMID:9755172   PMID:12081133   PMID:12446692   PMID:12477932   PMID:14530442   PMID:15565366   PMID:15634692   PMID:16462943   PMID:17084361   PMID:18403418   PMID:19690046   PMID:20081117  
PMID:20711497   PMID:20940257   PMID:21073445   PMID:21401405   PMID:21884692   PMID:22082260   PMID:24647564   PMID:24662752   PMID:24854956   PMID:26345464   PMID:26525805   PMID:26659076  
PMID:31076992   PMID:32114773  


Genomics

Comparative Map Data
Sox6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,157,678 - 179,769,243 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1179,163,566 - 179,711,727 (-)EnsemblGRCr8
mRatBN7.21169,723,306 - 170,334,846 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,729,194 - 170,277,386 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1178,052,031 - 178,553,600 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,238,507 - 185,740,114 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01177,945,239 - 178,446,677 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01185,631,702 - 186,186,192 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,673,177 - 186,182,829 (+)Ensemblrn6Rnor6.0
Rnor_5.01192,644,288 - 193,155,831 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41173,556,966 - 174,069,437 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,560,079 - 168,058,656 (-)NCBICelera
RGSC_v3.11173,696,212 - 174,208,683 (-)NCBI
Cytogenetic Map1q35NCBI
SOX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381115,966,449 - 16,738,477 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1115,966,449 - 16,739,591 (-)Ensemblhg38GRCh38
GRCh371115,987,995 - 16,760,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361115,948,371 - 16,454,494 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341115,949,899 - 16,454,494NCBI
Celera1116,115,232 - 16,625,247 (-)NCBICelera
Cytogenetic Map11p15.2NCBI
HuRef1115,673,238 - 16,183,365 (-)NCBIHuRef
CHM1_11115,987,568 - 16,497,588 (-)NCBICHM1_1
T2T-CHM13v2.01116,064,414 - 16,835,856 (-)NCBIT2T-CHM13v2.0
Sox6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397115,070,107 - 115,639,186 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7115,070,107 - 115,638,031 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm387115,470,872 - 116,040,776 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7115,470,872 - 116,038,796 (-)Ensemblmm10GRCm38
MGSCv377122,614,858 - 123,182,258 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv367115,262,493 - 115,822,196 (-)NCBIMGSCv36mm8
Celera7115,422,369 - 115,985,959 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map761.29NCBI
Sox6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541430,971,920 - 31,335,263 (-)Ensembl
ChiLan1.0NW_00495541430,965,626 - 31,532,473 (-)NCBIChiLan1.0ChiLan1.0
SOX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2918,332,384 - 19,101,613 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11118,293,187 - 19,062,516 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01116,053,730 - 16,488,566 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11115,747,495 - 16,175,439 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1115,747,495 - 16,175,246 (-)EnsemblpanPan2panpan1.1
SOX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12138,737,072 - 39,320,257 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2138,737,247 - 39,216,549 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2138,232,821 - 38,820,718 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02139,826,638 - 40,154,574 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2139,829,824 - 40,155,369 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12138,844,094 - 39,431,782 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02139,056,763 - 39,644,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02139,389,267 - 39,977,587 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sox6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494746,297,725 - 46,878,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365282,331,661 - 2,906,082 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365282,331,706 - 2,912,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl242,453,681 - 43,068,325 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1242,447,391 - 43,068,824 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2246,096,295 - 46,213,212 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SOX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1148,206,243 - 48,955,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038145,770,561 - 146,435,141 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sox6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247667,689,775 - 8,084,764 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247667,683,492 - 8,301,823 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sox6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1285,535,369 - 86,076,163 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sox6
5017 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:153
Count of miRNA genes:118
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000048020
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)1137611478182611478Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1142582336182383862Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1140833106185833106Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1153680016182383862Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1153680016183564652Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1175967553200707874Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1178547286206690557Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1170078537182384005Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436180021436Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1140915717185915717Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat

Markers in Region
D1Rat281  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81179,358,098 - 179,358,243 (+)Marker Load Pipeline
mRatBN7.21169,923,731 - 169,923,880 (-)MAPPERmRatBN7.2
Rnor_6.01185,988,399 - 185,988,543NCBIRnor6.0
Rnor_5.01192,957,333 - 192,957,477UniSTSRnor5.0
RGSC_v3.41173,757,797 - 173,757,942RGDRGSC3.4
RGSC_v3.41173,757,798 - 173,757,942UniSTSRGSC3.4
Celera1167,754,585 - 167,754,729UniSTS
RGSC_v3.11173,897,043 - 173,897,188RGD
SHRSP x BN Map185.7999UniSTS
SHRSP x BN Map185.7999RGD
Cytogenetic Map1q34UniSTS
UniSTS:144491  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,729,239 - 169,729,409 (-)MAPPERmRatBN7.2
Rnor_6.01186,182,614 - 186,182,783NCBIRnor6.0
Rnor_5.01193,151,399 - 193,151,568UniSTSRnor5.0
RGSC_v3.41173,557,013 - 173,557,182UniSTSRGSC3.4
Celera1167,560,126 - 167,560,295UniSTS
Cytogenetic Map1q34UniSTS
STS-H69535  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,910,327 - 169,910,482 (-)MAPPERmRatBN7.2
Rnor_6.01186,001,797 - 186,001,951NCBIRnor6.0
Rnor_5.01192,970,731 - 192,970,885UniSTSRnor5.0
RGSC_v3.41173,744,390 - 173,744,544UniSTSRGSC3.4
Celera1167,741,178 - 167,741,332UniSTS
Cytogenetic Map1q34UniSTS
U32614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,729,183 - 169,729,343 (-)MAPPERmRatBN7.2
Rnor_6.01186,182,680 - 186,182,839NCBIRnor6.0
Rnor_5.01193,151,465 - 193,151,624UniSTSRnor5.0
RGSC_v3.41173,556,957 - 173,557,116UniSTSRGSC3.4
Celera1167,560,070 - 167,560,229UniSTS
Cytogenetic Map1q34UniSTS
Sox6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,729,304 - 169,729,541 (-)MAPPERmRatBN7.2
Rnor_6.01186,182,482 - 186,182,718NCBIRnor6.0
Rnor_5.01193,151,267 - 193,151,503UniSTSRnor5.0
RGSC_v3.41173,557,078 - 173,557,314UniSTSRGSC3.4
Celera1167,560,191 - 167,560,427UniSTS
Cytogenetic Map1q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
17 13 79 188 91 90 59 90 59 6 400 212 22 164 104 109 31 29 29

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000048020   ⟹   ENSRNOP00000044088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,163,566 - 179,665,371 (-)Ensembl
mRatBN7.2 Ensembl1169,729,194 - 170,231,022 (-)Ensembl
Rnor_6.0 Ensembl1185,673,177 - 186,182,829 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079072   ⟹   ENSRNOP00000068898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,163,566 - 179,484,511 (-)Ensembl
mRatBN7.2 Ensembl1169,729,194 - 170,050,118 (-)Ensembl
Rnor_6.0 Ensembl1185,863,043 - 186,182,828 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094350   ⟹   ENSRNOP00000079879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,163,566 - 179,711,727 (-)Ensembl
mRatBN7.2 Ensembl1169,729,194 - 170,277,386 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000127672   ⟹   ENSRNOP00000110779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,163,566 - 179,484,626 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000157212   ⟹   ENSRNOP00000107216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,163,566 - 179,484,511 (-)Ensembl
RefSeq Acc Id: NM_001024751   ⟹   NP_001019922
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,163,565 - 179,665,371 (-)NCBI
mRatBN7.21169,729,193 - 170,231,022 (-)NCBI
Rnor_6.01185,673,177 - 186,182,830 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
RGSC_v3.41173,556,966 - 174,069,437 (-)RGD
Celera1167,560,079 - 168,058,656 (-)RGD
Sequence:
RefSeq Acc Id: XM_006230087   ⟹   XP_006230149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,821 (-)NCBI
mRatBN7.21169,729,392 - 170,051,487 (-)NCBI
Rnor_6.01185,851,620 - 186,186,192 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006230091   ⟹   XP_006230153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,504,960 (-)NCBI
mRatBN7.21169,723,306 - 170,069,436 (-)NCBI
Rnor_6.01185,836,253 - 186,186,192 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006230092   ⟹   XP_006230154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,813 (-)NCBI
mRatBN7.21169,729,392 - 170,051,481 (-)NCBI
Rnor_6.01185,851,621 - 186,186,192 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006230093   ⟹   XP_006230155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,812 (-)NCBI
mRatBN7.21169,729,392 - 170,051,480 (-)NCBI
Rnor_6.01185,851,621 - 186,186,192 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006230094   ⟹   XP_006230156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,817 (-)NCBI
mRatBN7.21169,723,306 - 170,051,481 (-)NCBI
Rnor_6.01185,851,621 - 186,186,192 (+)NCBI
Rnor_5.01192,644,288 - 193,155,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588968   ⟹   XP_017444457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,483,627 (-)NCBI
mRatBN7.21169,723,306 - 170,049,275 (-)NCBI
Rnor_6.01185,863,326 - 186,186,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039106301   ⟹   XP_038962229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,822 (-)NCBI
mRatBN7.21169,723,306 - 170,051,485 (-)NCBI
RefSeq Acc Id: XM_039106304   ⟹   XP_038962232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,825 (-)NCBI
mRatBN7.21169,723,306 - 170,051,488 (-)NCBI
RefSeq Acc Id: XM_039106313   ⟹   XP_038962241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,485,824 (-)NCBI
mRatBN7.21169,729,392 - 170,051,490 (-)NCBI
RefSeq Acc Id: XM_039106327   ⟹   XP_038962255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
mRatBN7.21169,723,306 - 170,334,846 (-)NCBI
RefSeq Acc Id: XM_039106328   ⟹   XP_038962256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,677,673 (-)NCBI
mRatBN7.21169,723,306 - 170,243,324 (-)NCBI
RefSeq Acc Id: XM_039106334   ⟹   XP_038962262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
mRatBN7.21169,723,306 - 170,334,846 (-)NCBI
RefSeq Acc Id: XM_039106338   ⟹   XP_038962266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,706,719 (-)NCBI
mRatBN7.21169,723,306 - 170,272,382 (-)NCBI
RefSeq Acc Id: XM_039106343   ⟹   XP_038962271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,705,435 (-)NCBI
mRatBN7.21169,723,306 - 170,271,086 (-)NCBI
RefSeq Acc Id: XM_039106354   ⟹   XP_038962282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,707,442 (-)NCBI
mRatBN7.21169,723,306 - 170,273,116 (-)NCBI
RefSeq Acc Id: XM_039106360   ⟹   XP_038962288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,623,733 (-)NCBI
mRatBN7.21169,723,306 - 170,190,592 (-)NCBI
RefSeq Acc Id: XM_039106363   ⟹   XP_038962291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,706,719 (-)NCBI
mRatBN7.21169,723,306 - 170,272,382 (-)NCBI
RefSeq Acc Id: XM_039106374   ⟹   XP_038962302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,667,819 (-)NCBI
mRatBN7.21169,723,306 - 170,233,502 (-)NCBI
RefSeq Acc Id: XM_039106377   ⟹   XP_038962305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,539,591 (-)NCBI
mRatBN7.21169,723,306 - 170,100,531 (-)NCBI
RefSeq Acc Id: XM_063285244   ⟹   XP_063141314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
RefSeq Acc Id: XM_063285245   ⟹   XP_063141315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
RefSeq Acc Id: XM_063285251   ⟹   XP_063141321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
RefSeq Acc Id: XM_063285274   ⟹   XP_063141344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,769,243 (-)NCBI
RefSeq Acc Id: XM_063285275   ⟹   XP_063141345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,539,591 (-)NCBI
RefSeq Acc Id: XM_063285278   ⟹   XP_063141348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,706,720 (-)NCBI
RefSeq Acc Id: XM_063285280   ⟹   XP_063141350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,623,734 (-)NCBI
RefSeq Acc Id: XM_063285281   ⟹   XP_063141351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,705,435 (-)NCBI
RefSeq Acc Id: XM_063285282   ⟹   XP_063141352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,707,442 (-)NCBI
RefSeq Acc Id: XM_063285283   ⟹   XP_063141353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,157,678 - 179,623,734 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001019922 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230149 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230153 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230154 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230155 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230156 (Get FASTA)   NCBI Sequence Viewer  
  XP_017444457 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962229 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962232 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962241 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962255 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962256 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962262 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962266 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962271 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962282 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962288 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962291 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962302 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962305 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141314 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141315 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141321 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141344 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141345 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141348 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141350 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141351 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141352 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141353 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0A0G2JTZ2 (Get FASTA)   NCBI Sequence Viewer  
  AAH97403 (Get FASTA)   NCBI Sequence Viewer  
  EDM17750 (Get FASTA)   NCBI Sequence Viewer  
  EDM17751 (Get FASTA)   NCBI Sequence Viewer  
  EDM17752 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044088
  ENSRNOP00000068898
  ENSRNOP00000079879
RefSeq Acc Id: NP_001019922   ⟸   NM_001024751
- UniProtKB: F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   Q4V8G3 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230153   ⟸   XM_006230091
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230149   ⟸   XM_006230087
- Peptide Label: isoform X2
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230156   ⟸   XM_006230094
- Peptide Label: isoform X8
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230154   ⟸   XM_006230092
- Peptide Label: isoform X6
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230155   ⟸   XM_006230093
- Peptide Label: isoform X7
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6R0V8A0 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444457   ⟸   XM_017588968
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068898   ⟸   ENSRNOT00000079072
Ensembl Acc Id: ENSRNOP00000044088   ⟸   ENSRNOT00000048020
RefSeq Acc Id: XP_038962262   ⟸   XM_039106334
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962255   ⟸   XM_039106327
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962282   ⟸   XM_039106354
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962266   ⟸   XM_039106338
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962291   ⟸   XM_039106363
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962271   ⟸   XM_039106343
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962256   ⟸   XM_039106328
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962302   ⟸   XM_039106374
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962288   ⟸   XM_039106360
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962305   ⟸   XM_039106377
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962232   ⟸   XM_039106304
- Peptide Label: isoform X3
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962229   ⟸   XM_039106301
- Peptide Label: isoform X1
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962241   ⟸   XM_039106313
- Peptide Label: isoform X4
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A6I8C8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079879   ⟸   ENSRNOT00000094350
RefSeq Acc Id: XP_063141314   ⟸   XM_063285244
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141344   ⟸   XM_063285274
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141321   ⟸   XM_063285251
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141315   ⟸   XM_063285245
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141352   ⟸   XM_063285282
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141348   ⟸   XM_063285278
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141351   ⟸   XM_063285281
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141353   ⟸   XM_063285283
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141350   ⟸   XM_063285280
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141345   ⟸   XM_063285275
- Peptide Label: isoform X5
- UniProtKB: Q4V8G3 (UniProtKB/Swiss-Prot),   F1MAJ5 (UniProtKB/Swiss-Prot),   A0A0G2JTZ2 (UniProtKB/Swiss-Prot),   A0A6I8PLH1 (UniProtKB/TrEMBL),   A6I8C8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107216   ⟸   ENSRNOT00000157212
Ensembl Acc Id: ENSRNOP00000110779   ⟸   ENSRNOT00000127672
Protein Domains
HMG box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTZ2-F1-model_v2 AlphaFold A0A0G2JTZ2 1-827 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309000 AgrOrtholog
BioCyc Gene G2FUF-57727 BioCyc
Ensembl Genes ENSRNOG00000020514 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000048020 ENTREZGENE
  ENSRNOT00000079072 ENTREZGENE
  ENSRNOT00000094350 ENTREZGENE
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7453944 IMAGE-MGC_LOAD
InterPro HMG_box_dom UniProtKB/Swiss-Prot
  HMG_box_dom_sf UniProtKB/Swiss-Prot
  SOX/SOX-like_TF UniProtKB/Swiss-Prot
KEGG Report rno:293165 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114448 IMAGE-MGC_LOAD
NCBI Gene 293165 ENTREZGENE
PANTHER FI18025P1 UniProtKB/Swiss-Prot
  PTHR45789:SF1 UniProtKB/Swiss-Prot
Pfam HMG_box UniProtKB/Swiss-Prot
PhenoGen Sox6 PhenoGen
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020514 RatGTEx
SMART HMG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot
UniProt A0A0G2JTZ2 ENTREZGENE
  A0A6I8PLH1 ENTREZGENE, UniProtKB/TrEMBL
  A0A6R0V8A0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNG0_RAT UniProtKB/TrEMBL
  A0ABK0LIP3_RAT UniProtKB/TrEMBL
  A0ABK0M1E3_RAT UniProtKB/TrEMBL
  A6I8C8 ENTREZGENE, UniProtKB/TrEMBL
  F1MAJ5 ENTREZGENE
  Q4V8G3 ENTREZGENE
  SOX6_RAT UniProtKB/Swiss-Prot
UniProt Secondary F1MAJ5 UniProtKB/Swiss-Prot
  Q4V8G3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Sox6  SRY-box transcription factor 6  LOC102549121  uncharacterized LOC102549121  Data merged from RGD:7508220 737654 PROVISIONAL
2019-08-05 Sox6  SRY-box transcription factor 6  Sox6  SRY box 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-12 Sox6  SRY box 6  Sox6  SRY (sex determining region Y)-box 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102549121  uncharacterized LOC102549121      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-18 Sox6  SRY (sex determining region Y)-box 6  Sox6  SRY-box containing gene 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sox6  SRY-box containing gene 6  Sox6_predicted  SRY-box containing gene 6 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sox6_predicted  SRY-box containing gene 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED