SOX6 (SRY (sex determining region Y)-box 6)

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Keyword

Gene: SOX6 (SRY (sex determining region Y)-box 6) Homo sapiens

Symbol:

SOX6

Name:

SRY (sex determining region Y)-box 6

Description:

This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

HSSOX6; OTTHUMP00000231372; OTTHUMP00000231373; OTTHUMP00000231374; OTTHUMP00000231375; SOXD; SRY-box containing gene 6; transcription factor SOX-6

Orthologs:

Mus musculus : Sox6 (SRY-box containing gene 6) MGI
Rattus norvegicus : Sox6 (SRY (sex determining region Y)-box 6)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	11	15,911,740 - 16,421,655	-	NCBI
Human Genome Assembly HuRef	11	15,673,238 - 16,183,365	-	NCBI
Human Genome Assembly GRCh37	11	15,987,995 - 16,497,935	-	NCBI
Human Genome Assembly Build 36	11	15,948,371 - 16,454,494	-	NCBI
Human Cytogenetic Map	11	p15.3		NCBI
Human Genome Assembly	11	15,949,899 - 16,454,494		NCBI