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Gene: Rpl7a (ribosomal protein L7A) Rattus norvegicus

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Symbol:

Rpl7a

Name:

ribosomal protein L7A

RGD ID:

1307586

Description:

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in cellular response to Thyroid stimulating hormone. Located in ribosome. Part of cytosolic large ribosomal subunit. Orthologous to human RPL7A (ribosomal protein L7a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

60S ribosomal protein L7a; large ribosomal subunit protein eL8; LOC296596

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPL7A (ribosomal protein L7a)	HGNC	HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Rpl7a (ribosomal protein L7A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rpl7a (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPL7A (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPL7A (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rpl7a (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RPL7A (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPL7A (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rpl7a (ribosomal protein L7a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RPL7A (ribosomal protein L7a)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RPL7A (ribosomal protein L7a)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Rpl7a (ribosomal protein L7A)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	rpl7a (ribosomal protein L7a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rpl7a (ribosomal protein L7a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL8A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL8A	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL8B	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL8B	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpL7A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpL7A	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpl-7A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpl-7A	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rpl7a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rpl7a	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Related Pseudogenes:

Rpl7a-ps1 Rpl7a-ps36

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	30,637,136 - 30,639,778 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	4,413,418 - 4,447,637 (-)	Ensembl				GRCr8
GRCr8 Ensembl	3	30,637,059 - 30,639,791 (+)	Ensembl				GRCr8
mRatBN7.2	3	10,239,026 - 10,241,703 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	4,172,029 - 4,172,931 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	3	10,239,001 - 10,241,716 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	13,299,056 - 13,301,699 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	21,884,457 - 21,887,100 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,139,758 - 20,142,401 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	5,458,985 - 5,461,627 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	5,459,160 - 5,461,583 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	3	4,867,233 - 4,869,656 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	10,820,895 - 10,823,537 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	5,807,901 - 5,810,543 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	5,037,091 - 5,039,733 (+)	NCBI		Celera
RGSC_v3.1	3	5,808,184 - 5,810,842 (+)	NCBI
Cytogenetic Map	3	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

(S)-nicotine (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,6-dimethoxyphenol (ISO)

2-naphthylamine (ISO)

2-nitrofluorene (EXP)

2-palmitoylglycerol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

4-phenylbutyric acid (ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antimycin A (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bexarotene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cylindrospermopsin (ISO)

decabromodiphenyl ether (ISO)

deoxynivalenol (ISO)

diethylstilbestrol (EXP)

disodium selenite (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

fenthion (ISO)

fipronil (EXP)

folic acid (ISO)

FR900359 (ISO)

furfural (ISO)

gentamycin (EXP)

ivermectin (ISO)

lead diacetate (EXP)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP)

methidathion (ISO)

N-nitrosodimethylamine (EXP)

nicotine (ISO)

Nutlin-3 (ISO)

ochratoxin A (ISO)

paracetamol (ISO)

parathion (ISO)

perfluorodecanoic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenanthrene (ISO)

piperonyl butoxide (EXP)

pirinixic acid (EXP)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium fluoride (ISO)

Soman (EXP)

sulforaphane (ISO)

tolcapone (EXP)

triphenyl phosphate (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to Thyroid stimulating hormone (IEP)

cytoplasmic translation (ISO)

maturation of LSU-rRNA (IBA)

ribosome biogenesis (IEA)

Cellular Component

cytoplasm (IEA,ISO)

cytosolic large ribosomal subunit (IBA,IDA,IEA,ISO)

cytosolic ribosome (ISO)

membrane (ISO)

nucleolus (ISO)

ribonucleoprotein complex (IEA)

ribosome (IDA,IEA,ISO)

synapse (ISO)

Molecular Function

protein binding (ISO)

RNA binding (IBA,IEA)

structural constituent of ribosome (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (ISO)

translation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structures of the human and Drosophila 80S ribosome.	Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2.	Thyrotropin-induced expression of a gene for a ribosomal protein related to the trk oncogene.	Chazenbalk GD, etal., Mol Cell Endocrinol. 1990 Jan 2;68(1):R25-30.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Selective high-efficiency cross-linking of mammalian ribosomal proteins with cleavable thiol-directed heterobifunctional reagents: identification and binding directions of major protein complexes.	Hultin T Biochim Biophys Acta. 1986 Aug 15;872(3):226-35.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation
8.	Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'.	Tsurugi K, etal., J Biol Chem. 1977 Jun 10;252(11):3961-9.
9.	The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons.	Zivraj KH, etal., J Neurochem. 2013 Mar;124(5):670-84. doi: 10.1111/jnc.12079. Epub 2013 Jan 20.

Additional References at PubMed

PMID:398910	PMID:2748341	PMID:10848616	PMID:12477932	PMID:12962325	PMID:16452087	PMID:16791210	PMID:21423176	PMID:21630459	PMID:22658674	PMID:22681889	PMID:23376485
PMID:24625528	PMID:25294810	PMID:25468996	PMID:30053369	PMID:31904090	PMID:35352799

Genomics

Comparative Map Data

Rpl7a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	30,637,136 - 30,639,778 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	4,413,418 - 4,447,637 (-)	Ensembl				GRCr8
GRCr8 Ensembl	3	30,637,059 - 30,639,791 (+)	Ensembl				GRCr8
mRatBN7.2	3	10,239,026 - 10,241,703 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	4,172,029 - 4,172,931 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	3	10,239,001 - 10,241,716 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	13,299,056 - 13,301,699 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	21,884,457 - 21,887,100 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,139,758 - 20,142,401 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	5,458,985 - 5,461,627 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	5,459,160 - 5,461,583 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	3	4,867,233 - 4,869,656 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	10,820,895 - 10,823,537 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	5,807,901 - 5,810,543 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	5,037,091 - 5,039,733 (+)	NCBI		Celera
RGSC_v3.1	3	5,808,184 - 5,810,842 (+)	NCBI
Cytogenetic Map	3	p13	NCBI

RPL7A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	133,348,218 - 133,351,426 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	133,348,194 - 133,351,435 (+)	Ensembl			hg38	GRCh38
GRCh37	9	136,215,073 - 136,218,281 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	135,204,890 - 135,208,101 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	133,244,622 - 133,247,834	NCBI
Celera	9	106,765,555 - 106,768,766 (+)	NCBI		Celera
Cytogenetic Map	9	q34.2	NCBI
HuRef	9	105,714,990 - 105,718,201 (+)	NCBI		HuRef
CHM1_1	9	136,365,233 - 136,368,444 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	145,562,158 - 145,565,366 (+)	NCBI		T2T-CHM13v2.0

Rpl7a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	26,800,697 - 26,803,330 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	26,800,776 - 26,803,330 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	26,910,685 - 26,913,312 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	26,910,764 - 26,913,318 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	26,766,327 - 26,768,831 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	26,732,816 - 26,735,320 (+)	NCBI		MGSCv36	mm8
Celera	2	26,620,552 - 26,623,056 (+)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.1	NCBI

Rpl7a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	2,704,355 - 2,707,744 (+)	Ensembl
ChiLan1.0	NW_004955513	2,703,765 - 2,707,803 (+)	NCBI	ChiLan1.0	ChiLan1.0

RPL7A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	6,001,961 - 6,005,250 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	6,004,297 - 6,007,500 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	104,471,317 - 104,474,619 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	133,082,079 - 133,085,340 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	133,082,079 - 133,085,340 (+)	Ensembl			panPan2	panpan1.1

RPL7A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	49,783,635 - 49,786,328 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	49,783,635 - 49,786,328 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	49,065,123 - 49,067,816 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	50,657,666 - 50,660,359 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	50,657,666 - 50,660,359 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	49,420,135 - 49,422,793 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	49,761,579 - 49,764,276 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	49,839,585 - 49,842,275 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rpl7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	199,840,472 - 199,842,829 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936669	3,532,139 - 3,534,586 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936669	3,532,139 - 3,534,586 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPL7A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	272,959,831 - 272,965,634 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	272,961,421 - 272,965,636 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RPL7A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	4,165,087 - 4,165,974 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666058	199,236 - 202,791 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rpl7a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	1,811,544 - 1,815,144 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624760	1,811,442 - 1,815,144 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Rpl7a
16 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	10
Count of miRNA genes:	5
Interacting mature miRNAs:	5
Transcripts:	ENSRNOT00000006754, ENSRNOT00000044551
Prediction methods:	Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29056275	47904329	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	36721849	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	29056275	47904329	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
19	2	30	114	68	60	36	79	36	12	255	144	11	89	56	70	24	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001114391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC159421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC162009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006754 ⟹ ENSRNOP00000006754

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	30,637,112 - 30,639,791 (+)	Ensembl
mRatBN7.2 Ensembl	3	10,239,060 - 10,241,716 (+)	Ensembl
Rnor_6.0 Ensembl	3	4,867,233 - 4,869,656 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000044551 ⟹ ENSRNOP00000063128

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	30,637,059 - 30,639,791 (+)	Ensembl
mRatBN7.2 Ensembl	3	10,239,001 - 10,241,703 (+)	Ensembl
Rnor_6.0 Ensembl	3	5,459,160 - 5,461,583 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000051207 ⟹ ENSRNOP00000049619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	4,172,029 - 4,172,931 (-)	Ensembl

RefSeq Acc Id:

NM_001114391 ⟹ NP_001107863

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	30,637,136 - 30,639,778 (+)	NCBI
mRatBN7.2	3	10,239,061 - 10,241,703 (+)	NCBI
Rnor_6.0	3	5,458,985 - 5,461,627 (+)	NCBI
Rnor_5.0	3	10,820,895 - 10,823,537 (+)	NCBI
RGSC_v3.4	18	5,807,901 - 5,810,543 (+)	RGD
Celera	3	5,037,091 - 5,039,733 (+)	NCBI

Sequence:

show sequence

GCAAGATGCCCAAAGGAAAGAAGGCCAAGGGGAAGAAGGTGGCCCCGGCCCCCGCCGTGGTCAA
GAAACAAGAGGCCAAAAAGGTGGTCAATCCTTTGTTTGAGAAAAGGCCTAAGAACTTCGGCATT
GGGCAGGACATCCAGCCCAAAAGAGATCTCACGCGCTTCGTCAAATGGCCCCGCTACATCAGGC
TGCAGCGGCAAAGAGCCATCCTCTATAAGCGGCTCAAAGTACCTCCTGCCATCAACCAGTTCAC
CCAGGCCCTGGACAGGCAAACAGCGACTCAGCTGCTTAAGCTTGCCCACAAGTACAGGCCAGAG
ACAAAGCAGGAGAAGAAGCAGAGGCTGCTGGCCCGCGCTGAGAAGAAAGCTGCTGGCAAAGGGG
ACGTCCCAACTAAGAGACCACCTGTCCTCCGAGCAGGGGTCAATACAGTCACCACTTTGGTGGA
GAACAAGAAGGCTCAGCTGGTGGTGATTGCCCATGATGTAGACCCCATTGAGCTGGTGGTTTTC
CTGCCTGCCCTGTGTCGAAAGATGGGGGTGCCCTACTGCATCATCAAGGGAAAGGCCAGGCTGG
GGCGCCTGGTCCACAGGAAGACATGCACCACTGTTGCCTTCACACAGGTGAACTCGGAAGACAA
GGGTGCTCTGGCTAAGCTGGTGGAAGCTATTAGGACCAATTATAATGACAGATATGACGAGATC
CGCCGCCACTGGGGAGGCAACGTCCTGGGTCCTAAGTCTGTGGCTCGCATTGCCAAGCTGGAAA
AGGCAAAGGCTAAAGAACTCGCCACTAAGCTGGGTTAAATGTACACTTAAGTTTTCTGTACATA
AATATAATTACAAAGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001107863	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI59422	(Get FASTA)	NCBI Sequence Viewer
	AAI62009	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063128
	ENSRNOP00000063128.3
GenBank Protein	P62425	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001107863 ⟸ NM_001114391
- UniProtKB:	P62425 (UniProtKB/Swiss-Prot), B0K021 (UniProtKB/TrEMBL), A6JTI5 (UniProtKB/TrEMBL), D3ZU22 (UniProtKB/TrEMBL), F1M013 (UniProtKB/TrEMBL), F2Z3S2 (UniProtKB/TrEMBL), B1WC55 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQ RQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGR LVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKA KAKELATKLG hide sequence

Ensembl Acc Id:

ENSRNOP00000006754 ⟸ ENSRNOT00000006754

Ensembl Acc Id:

ENSRNOP00000063128 ⟸ ENSRNOT00000044551

Ensembl Acc Id:

ENSRNOP00000049619 ⟸ ENSRNOT00000051207

Protein Domains

Ribosomal protein eL8/eL30/eS12/Gadd45

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P62425-F1-model_v2	AlphaFold	P62425	1-266	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307586	AgrOrtholog
BioCyc Gene	G2FUF-50329	BioCyc
Ensembl Genes	ENSRNOG00000031244	Ensembl
	ENSRNOG00000047737	Ensembl
	ENSRNOG00000049097	Ensembl
	ENSRNOG00000070974	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000044551	ENTREZGENE
	ENSRNOT00000044551.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.1330.30	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:8374311	IMAGE-MGC_LOAD
	IMAGE:9090599	IMAGE-MGC_LOAD
InterPro	eL8_RNA-proc_assembly	UniProtKB/Swiss-Prot
	L30e-like	UniProtKB/Swiss-Prot
	Ribosomal_L7A/L8	UniProtKB/Swiss-Prot
	Ribosomal_L7Ae/L30e/S12e/Gad45	UniProtKB/Swiss-Prot
	Ribosomal_L7Ae/L8/Nhp2	UniProtKB/Swiss-Prot
	Ribosomal_L7Ae_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:296596	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:187871	IMAGE-MGC_LOAD
	MGC:188716	IMAGE-MGC_LOAD
NCBI Gene	296596	ENTREZGENE
PANTHER	RIBOSOMAL PROTEIN L7AE FAMILY MEMBER	UniProtKB/Swiss-Prot
Pfam	Ribosomal_L7Ae	UniProtKB/Swiss-Prot
PhenoGen	Rpl7a	PhenoGen
PRINTS	L7ARS6FAMILY	UniProtKB/Swiss-Prot
	RIBOSOMALL7A	UniProtKB/Swiss-Prot
PROSITE	RIBOSOMAL_L7AE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000031244	RatGTEx
	ENSRNOG00000047737	RatGTEx
	ENSRNOG00000049097	RatGTEx
	ENSRNOG00000070974	RatGTEx
Superfamily-SCOP	SSF55315	UniProtKB/Swiss-Prot
UniProt	A6JTI5	ENTREZGENE, UniProtKB/TrEMBL
	B0K021	ENTREZGENE
	B1WC55	ENTREZGENE, UniProtKB/TrEMBL
	D3ZU22	ENTREZGENE, UniProtKB/TrEMBL
	F1M013	ENTREZGENE, UniProtKB/TrEMBL
	F1M1M2_RAT	UniProtKB/TrEMBL
	F2Z3S2	ENTREZGENE
	P62425	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	P11518	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-04-07	Rpl7a	ribosomal protein L7A	Rpl7a	ribosomal protein L7a	Name changed	629549	APPROVED
2008-04-30	Rpl7a	ribosomal protein L7a	Rpl7a_predicted	ribosomal protein L7a (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rpl7a_predicted	ribosomal protein L7a (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations