Gene: Mdga1 (MAM domain containing glycosylphosphatidylinositol anchor 1) Rattus norvegicus
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Symbol:
Mdga1
Name:
MAM domain containing glycosylphosphatidylinositol anchor 1
RGD ID:
1307031
Description:
Involved in central nervous system development and regulation of synapse organization. Located in plasma membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic density membrane. Orthologous to human MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
ig6M; LOC309659; MAM domain-containing glycosylphosphatidylinositol anchor protein 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 7,901,856 - 7,965,834 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 20 7,901,856 - 7,965,834 (-) Ensembl GRCr8 mRatBN7.2 20 7,900,327 - 7,964,309 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 7,904,358 - 7,963,471 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 20 8,600,465 - 8,659,560 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 7,961,630 - 8,020,725 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 8,434,933 - 8,493,730 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 8,515,142 - 8,574,632 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 8,515,142 - 8,574,082 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 20 10,707,850 - 10,766,734 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 20 8,149,686 - 8,200,149 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 20 9,435,545 - 9,495,254 (-) NCBI Celera RGSC_v3.1 20 8,150,174 - 8,245,666 (-) NCBI Cytogenetic Map 20 p12 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Mdga1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Mdga1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mdga1 Rat 1,2-dichloroethane decreases expression ISO Mdga1 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of MDGA1 mRNA CTD PMID:28960355 Mdga1 Rat 17beta-estradiol multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of MDGA1 mRNA CTD PMID:30165855 Mdga1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Mdga1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mdga1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Mdga1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mdga1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of MDGA1 mRNA CTD PMID:33387578 Mdga1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of MDGA1 mRNA CTD PMID:32109520 Mdga1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Mdga1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mdga1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Mdga1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Mdga1 (Mus musculus) 6480464 bisphenol S results in decreased expression of MDGA1 mRNA CTD PMID:30951980 Mdga1 Rat 4,4'-sulfonyldiphenol affects methylation ISO Mdga1 (Mus musculus) 6480464 bisphenol S affects the methylation of MDGA1 gene CTD PMID:31683443 Mdga1 Rat 4,4'-sulfonyldiphenol increases methylation ISO Mdga1 (Mus musculus) 6480464 bisphenol S results in increased methylation of MDGA1 exon CTD PMID:33297965 Mdga1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MDGA1 mRNA CTD PMID:25825206 Mdga1 Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of MDGA1 mRNA CTD PMID:28959563 Mdga1 Rat acrylamide decreases expression ISO MDGA1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of MDGA1 mRNA CTD PMID:32763439 Mdga1 Rat aflatoxin B1 decreases methylation ISO MDGA1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of MDGA1 gene; Aflatoxin B1 results in decreased methylation more ... CTD PMID:27153756|PMID:30157460 Mdga1 Rat Aflatoxin B2 alpha decreases methylation ISO MDGA1 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of MDGA1 intron CTD PMID:30157460 Mdga1 Rat all-trans-retinoic acid multiple interactions ISO Mdga1 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MDGA1 mRNA CTD PMID:36189433 Mdga1 Rat all-trans-retinoic acid decreases expression ISO Mdga1 (Mus musculus) 6480464 Tretinoin results in decreased expression of MDGA1 mRNA CTD PMID:36189433 Mdga1 Rat aristolochic acid A increases expression ISO MDGA1 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of MDGA1 mRNA CTD PMID:33212167 Mdga1 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of MDGA1 gene CTD PMID:35440735 Mdga1 Rat benzo[a]pyrene affects methylation ISO MDGA1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MDGA1 intron CTD PMID:30157460 Mdga1 Rat benzo[a]pyrene decreases methylation ISO MDGA1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of MDGA1 promoter CTD PMID:27901495 Mdga1 Rat beta-lapachone increases expression ISO MDGA1 (Homo sapiens) 6480464 beta-lapachone results in increased expression of MDGA1 mRNA CTD PMID:38218311 Mdga1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO MDGA1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of MDGA1 mRNA CTD PMID:31163220 Mdga1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MDGA1 mRNA CTD PMID:25181051|PMID:30816183|PMID:36779543 Mdga1 Rat bisphenol A decreases expression ISO Mdga1 (Mus musculus) 6480464 bisphenol A results in decreased expression of MDGA1 mRNA CTD PMID:32156529 Mdga1 Rat bisphenol A increases expression ISO Mdga1 (Mus musculus) 6480464 bisphenol A results in increased expression of MDGA1 mRNA CTD PMID:32370801 Mdga1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MDGA1 mRNA CTD PMID:29097150|PMID:34947998 Mdga1 Rat bisphenol A multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MDGA1 gene; [INS protein co-treated more ... CTD PMID:28628672|PMID:31601247 Mdga1 Rat bisphenol F decreases expression ISO Mdga1 (Mus musculus) 6480464 bisphenol F results in decreased expression of MDGA1 mRNA CTD PMID:30951980 Mdga1 Rat butanal decreases expression ISO MDGA1 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of MDGA1 mRNA CTD PMID:26079696 Mdga1 Rat Butylbenzyl phthalate decreases expression ISO Mdga1 (Mus musculus) 6480464 butylbenzyl phthalate results in decreased expression of MDGA1 mRNA CTD PMID:28392331 Mdga1 Rat cantharidin decreases expression ISO Mdga1 (Mus musculus) 6480464 Cantharidin results in decreased expression of MDGA1 mRNA CTD PMID:36907384 Mdga1 Rat carbon nanotube increases expression ISO Mdga1 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of MDGA1 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25554681 Mdga1 Rat CGP 52608 multiple interactions ISO MDGA1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to MDGA1 gene] CTD PMID:28238834 Mdga1 Rat chlorpyrifos increases expression ISO Mdga1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of MDGA1 mRNA CTD PMID:37019170 Mdga1 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of MDGA1 mRNA CTD PMID:27523638 Mdga1 Rat DDE decreases expression ISO MDGA1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of MDGA1 mRNA CTD PMID:38568856 Mdga1 Rat dexamethasone multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Mdga1 Rat dorsomorphin multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdga1 Rat doxorubicin increases expression ISO MDGA1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of MDGA1 mRNA CTD PMID:30031762 Mdga1 Rat doxorubicin decreases expression ISO Mdga1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of MDGA1 mRNA CTD PMID:39631538 Mdga1 Rat epoxiconazole affects expression ISO Mdga1 (Mus musculus) 6480464 epoxiconazole affects the expression of MDGA1 mRNA CTD PMID:35436446 Mdga1 Rat esketamine increases expression ISO MDGA1 (Homo sapiens) 6480464 Esketamine results in increased expression of MDGA1 mRNA CTD PMID:38219984 Mdga1 Rat ethanol affects expression ISO Mdga1 (Mus musculus) 6480464 Ethanol affects the expression of MDGA1 mRNA CTD PMID:30319688 Mdga1 Rat ethanol increases expression ISO Mdga1 (Mus musculus) 6480464 Ethanol results in increased expression of MDGA1 mRNA CTD PMID:30319688 Mdga1 Rat fulvestrant multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MDGA1 gene CTD PMID:31601247 Mdga1 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of MDGA1 mRNA CTD PMID:33387578 Mdga1 Rat indometacin multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Mdga1 Rat isoprenaline decreases expression ISO Mdga1 (Mus musculus) 6480464 Isoproterenol results in decreased expression of MDGA1 mRNA CTD PMID:20003209 Mdga1 Rat Licochalcone B increases expression ISO MDGA1 (Homo sapiens) 6480464 licochalcone B results in increased expression of MDGA1 mRNA CTD PMID:33647349 Mdga1 Rat maneb multiple interactions ISO Mdga1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MDGA1 mRNA CTD PMID:36117858 Mdga1 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of MDGA1 gene CTD PMID:35440735 Mdga1 Rat mono(2-ethylhexyl) phthalate decreases expression ISO Mdga1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA CTD PMID:22401849 Mdga1 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Mdga1 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MDGA1 mRNA CTD PMID:36189433 Mdga1 Rat mono(2-ethylhexyl) phthalate decreases expression ISO MDGA1 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA CTD PMID:36695872 Mdga1 Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of MDGA1 gene CTD PMID:33148267 Mdga1 Rat okadaic acid increases expression ISO MDGA1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of MDGA1 mRNA CTD PMID:38832940 Mdga1 Rat paracetamol affects expression ISO Mdga1 (Mus musculus) 6480464 Acetaminophen affects the expression of MDGA1 mRNA CTD PMID:17562736 Mdga1 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MDGA1 mRNA CTD PMID:33387578 Mdga1 Rat paracetamol increases expression ISO MDGA1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of MDGA1 mRNA CTD PMID:29067470 Mdga1 Rat paracetamol decreases expression ISO MDGA1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of MDGA1 mRNA CTD PMID:26690555 Mdga1 Rat paraquat multiple interactions ISO Mdga1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MDGA1 mRNA CTD PMID:36117858 Mdga1 Rat PCB138 multiple interactions ISO Mdga1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mdga1 Rat permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of MDGA1 gene CTD PMID:33148267 Mdga1 Rat SB 431542 multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdga1 Rat silicon dioxide decreases expression ISO MDGA1 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of MDGA1 mRNA CTD PMID:25895662 Mdga1 Rat sodium arsenite increases expression ISO MDGA1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of MDGA1 mRNA CTD PMID:34032870 Mdga1 Rat sodium arsenite decreases expression ISO Mdga1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of MDGA1 mRNA CTD PMID:37682722 Mdga1 Rat sodium arsenite decreases expression ISO MDGA1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MDGA1 mRNA CTD PMID:39719251 Mdga1 Rat sotorasib multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA CTD PMID:36139627 Mdga1 Rat sunitinib decreases expression ISO MDGA1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of MDGA1 mRNA CTD PMID:31533062 Mdga1 Rat thiram increases expression ISO MDGA1 (Homo sapiens) 6480464 Thiram results in increased expression of MDGA1 mRNA CTD PMID:38568856 Mdga1 Rat titanium dioxide increases methylation ISO Mdga1 (Mus musculus) 6480464 titanium dioxide results in increased methylation of MDGA1 gene; titanium dioxide results in increased methylation more ... CTD PMID:35295148 Mdga1 Rat titanium dioxide affects expression ISO Mdga1 (Mus musculus) 6480464 titanium dioxide affects the expression of MDGA1 mRNA CTD PMID:35295148 Mdga1 Rat titanium dioxide decreases methylation ISO Mdga1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of MDGA1 gene; titanium dioxide results in decreased methylation more ... CTD PMID:35295148 Mdga1 Rat trametinib multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA CTD PMID:36139627 Mdga1 Rat triptonide increases expression ISO Mdga1 (Mus musculus) 6480464 triptonide results in increased expression of MDGA1 mRNA CTD PMID:33045310 Mdga1 Rat valproic acid increases expression ISO MDGA1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of MDGA1 mRNA CTD PMID:26272509 Mdga1 Rat valproic acid multiple interactions ISO MDGA1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386