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Gene: Neurl1 (neuralized E3 ubiquitin protein ligase 1) Rattus norvegicus

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Symbol:

Neurl1

Name:

neuralized E3 ubiquitin protein ligase 1

RGD ID:

1307021

Description:

Predicted to enable translation regulator activity and ubiquitin protein ligase activity. Involved in skeletal muscle tissue development. Predicted to be located in cytoplasm; dendrite; and perikaryon. Predicted to be active in glutamatergic synapse; plasma membrane; and postsynaptic density. Orthologous to human NEURL1 (neuralized E3 ubiquitin protein ligase 1); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E3 ubiquitin-protein ligase NEURL1; LOC309459; neuralized homolog; neuralized homolog 1A; neuralized homolog 1A (Drosophila); neuralized-like; neuralized-like (Drosophila); neuralized-like homolog; neuralized-like homolog (Drosophila); neuralized-like protein 1A; Neurl; Neurl1a

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	RGD	RGD
Mus musculus (house mouse):	Neurl1a (neuralized E3 ubiquitin protein ligase 1A)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Neurl1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Neurl1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Neurl1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Neurl1 (neuralized E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NEURL1 (neuralized E3 ubiquitin protein ligase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Neurl1a (neuralized E3 ubiquitin protein ligase 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	neurl1aa (neuralized E3 ubiquitin protein ligase 1Aa)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F10D7.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F10D7.5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	neur	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	neur	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	neurl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	neurl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	256,008,012 - 256,094,219 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	256,008,160 - 256,094,224 (+)	Ensembl				GRCr8
mRatBN7.2	1	246,066,830 - 246,152,890 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	246,067,100 - 246,152,903 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	254,193,488 - 254,279,285 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	260,887,323 - 260,973,172 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	253,535,819 - 253,621,537 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	266,953,006 - 267,038,879 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	266,952,561 - 267,038,883 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	274,383,360 - 274,469,446 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	252,502,664 - 252,573,249 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	241,838,929 - 241,904,988 (+)	NCBI		Celera
RGSC_v3.1	1	252,767,229 - 252,856,359 (+)	NCBI
Cytogenetic Map	1	q54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

Colorectal Neoplasms (ISO)

Experimental Seizures (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium dichloride (EXP,ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (EXP)

cyclosporin A (ISO)

diallyl disulfide (ISO)

Diallyl sulfide (ISO)

disodium selenite (ISO)

divanadium pentaoxide (ISO)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

L-methionine (ISO)

maneb (ISO)

methoxychlor (EXP)

mifepristone (ISO)

N,N-diethyl-m-toluamide (EXP)

naled (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

PCB138 (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

pirinixic acid (ISO)

potassium dichromate (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone enanthate (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to amino acid stimulus (IEA,ISO)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of Notch signaling pathway (IEA,ISO)

Notch signaling pathway (IEA)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of dendritic spine development (IEA,ISO)

positive regulation of filopodium assembly (IEA,ISO)

positive regulation of long-term neuronal synaptic plasticity (IBA,IEA,ISO)

positive regulation of synapse maturation (IEA,ISO)

protein monoubiquitination (IEA,ISO)

regulation of cell communication (IEA)

regulation of Notch signaling pathway (IBA)

regulation of signaling (IEA)

regulation of translation (IEA)

skeletal muscle tissue development (IEP)

Cellular Component

apical dendrite (IEA,ISO)

dendrite (IEA)

dendritic spine (IEA,ISO)

perikaryon (IEA,ISO)

perinuclear region of cytoplasm (IEA)

plasma membrane (IBA,IEA,ISO)

postsynaptic density (IBA,IEA,ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

transferase activity (IEA)

translation regulator activity (IEA,ISO)

ubiquitin protein ligase activity (IBA,IEA)

ubiquitin-protein transferase activity (IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Notch signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation
5.	Regulation of notch signaling activity.	Schweisguth F, Curr Biol. 2004 Feb 3;14(3):R129-38.
6.	Dendritic localization of mammalian neuralized mRNA encoding a protein with transcription repression activities.	Timmusk T, etal., Mol Cell Neurosci. 2002 Aug;20(4):649-68.

Additional References at PubMed

PMID:11481456	PMID:11585928	PMID:11997106	PMID:20847082	PMID:22153079	PMID:27780737	PMID:31068605

Genomics

Comparative Map Data

Neurl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	256,008,012 - 256,094,219 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	256,008,160 - 256,094,224 (+)	Ensembl				GRCr8
mRatBN7.2	1	246,066,830 - 246,152,890 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	246,067,100 - 246,152,903 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	254,193,488 - 254,279,285 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	260,887,323 - 260,973,172 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	253,535,819 - 253,621,537 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	266,953,006 - 267,038,879 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	266,952,561 - 267,038,883 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	274,383,360 - 274,469,446 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	252,502,664 - 252,573,249 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	241,838,929 - 241,904,988 (+)	NCBI		Celera
RGSC_v3.1	1	252,767,229 - 252,856,359 (+)	NCBI
Cytogenetic Map	1	q54	NCBI

NEURL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	103,493,705 - 103,592,546 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	103,493,705 - 103,592,546 (+)	Ensembl			hg38	GRCh38
GRCh37	10	105,253,462 - 105,352,303 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	105,244,038 - 105,342,293 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	105,244,037 - 105,342,292	NCBI
Celera	10	98,993,672 - 99,092,247 (+)	NCBI		Celera
Cytogenetic Map	10	q24.33	NCBI
HuRef	10	98,884,519 - 99,014,405 (+)	NCBI		HuRef
CHM1_1	10	105,537,848 - 105,636,430 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	104,381,009 - 104,479,861 (+)	NCBI		T2T-CHM13v2.0

Neurl1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	47,167,259 - 47,247,880 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	47,167,259 - 47,247,880 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	19	47,178,820 - 47,259,441 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	47,178,820 - 47,259,441 (+)	Ensembl			mm10	GRCm38
MGSCv37	19	47,253,310 - 47,333,931 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	19	47,232,131 - 47,312,752 (+)	NCBI		MGSCv36	mm8
Celera	19	47,936,911 - 48,016,141 (+)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	39.39	NCBI

Neurl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955485	7,015,969 - 7,046,089 (-)	NCBI	ChiLan1.0	ChiLan1.0

NEURL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	115,380,176 - 115,477,017 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	115,385,505 - 115,482,346 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	100,093,614 - 100,192,485 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	103,554,939 - 103,653,928 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

NEURL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	15,856,494 - 15,935,897 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	15,856,616 - 15,933,763 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	16,028,329 - 16,107,610 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	16,332,801 - 16,412,233 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	16,332,895 - 16,412,228 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	15,881,613 - 15,960,831 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	15,909,624 - 15,988,946 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	16,048,129 - 16,127,416 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Neurl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	30,916,638 - 30,987,111 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	2,518,265 - 2,590,344 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	2,518,193 - 2,590,336 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEURL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	114,437,045 - 114,516,721 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	114,436,887 - 114,515,713 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	124,318,621 - 124,395,945 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEURL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	96,542,046 - 96,641,912 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	96,542,473 - 96,639,761 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	57,658,166 - 57,766,031 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Neurl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624831	2,717,226 - 2,778,977 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624831	2,717,184 - 2,778,907 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Neurl1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	46,709,549 - 46,792,481 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Neurl1
551 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	32
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000054696
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	224633915	269633915	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	232312773	270518180	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	226175591	270518180	Rat
1578775	Iddm21	Insulin dependent diabetes mellitus QTL 21	4.13		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	245782829	270518180	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	212738576	257738576	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	218829748	263829748	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	248619887	269633915	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	5e-06	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	247133834	270518180	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	237995023	269633915	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	233480549	270108840	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	234540191	270518180	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	233204160	270518180	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	233480549	270108840	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
1598839	Rf56	Renal function QTL 56			renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	255849111	270518180	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	241569529	269633915	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	223134011	262090599	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	243953669	270518180	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	225108840	270108840	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	226175591	270518180	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233349180	270518180	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	228174566	270518180	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	228180370	266453608	Rat

Markers in Region

D1Rat452

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	246,126,055 - 246,126,259 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	267,012,043 - 267,012,248	NCBI	Rnor6.0
Rnor_5.0	1	274,443,023 - 274,443,228	UniSTS	Rnor5.0
RGSC_v3.4	1	252,564,842 - 252,565,047	UniSTS	RGSC3.4
RGSC_v3.4	1	252,564,841 - 252,565,047	RGD	RGSC3.4
Celera	1	241,896,581 - 241,896,786	UniSTS
RGSC_v3.1	1	252,829,415 - 252,829,620	RGD
RH 3.4 Map	1	1643.2	RGD
RH 3.4 Map	1	1643.2	UniSTS
SHRSP x BN Map	1	139.09	RGD
SHRSP x BN Map	1	139.09	UniSTS
Cytogenetic Map	1	q54	UniSTS

BE097027

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	246,151,903 - 246,152,071 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	267,037,893 - 267,038,060	NCBI	Rnor6.0
Rnor_5.0	1	274,468,872 - 274,469,039	UniSTS	Rnor5.0
RGSC_v3.4	1	252,592,543 - 252,592,710	UniSTS	RGSC3.4
Celera	1	241,922,431 - 241,922,598	UniSTS
RH 3.4 Map	1	1641.6	UniSTS
Cytogenetic Map	1	q54	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	64	161	84	83	52	79	52	6	330	176	11	140	78	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097415	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC112451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000054696 ⟹ ENSRNOP00000051580

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	256,008,430 - 256,075,792 (+)	Ensembl
mRatBN7.2 Ensembl	1	246,067,100 - 246,134,461 (+)	Ensembl
Rnor_6.0 Ensembl	1	266,953,139 - 267,020,450 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076452 ⟹ ENSRNOP00000068189

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	256,062,942 - 256,094,221 (+)	Ensembl
mRatBN7.2 Ensembl	1	246,121,731 - 246,152,903 (+)	Ensembl
Rnor_6.0 Ensembl	1	266,952,561 - 267,038,883 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112299 ⟹ ENSRNOP00000079455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	256,008,160 - 256,094,219 (+)	Ensembl
mRatBN7.2 Ensembl	1	246,067,100 - 246,152,903 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129899 ⟹ ENSRNOP00000106458

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	256,063,817 - 256,094,224 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165645 ⟹ ENSRNOP00000103765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	256,008,160 - 256,094,218 (+)	Ensembl

RefSeq Acc Id:

NM_001107605 ⟹ NP_001101075

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,008,430 - 256,075,792 (+)	NCBI
mRatBN7.2	1	246,067,100 - 246,134,461 (+)	NCBI
Rnor_6.0	1	266,953,139 - 267,020,450 (+)	NCBI
Rnor_5.0	1	274,383,360 - 274,469,446 (+)	NCBI
RGSC_v3.4	1	252,502,664 - 252,573,249 (+)	RGD
Celera	1	241,838,929 - 241,904,988 (+)	RGD

Sequence:

show sequence

GCACACCTTTCCTCCGCTTGTGCCCAGCCTCGCCTGGCCCCCGCCGGAGCACCCCAGGGGGGCC
GATGCCATGGGTAACAACTTCTCCAGTGTCTCCTCTCTGCAGCGAGGAAACCCCAGCCGTGCGT
CGCGGGGCCACCCCCAGAACCTCAAAGACTCCATCGGGAGCTCCTTCCCGGTCCCCTCTCACCG
ATGCCATCACAAGCAGAAGCATTGCCCGCCCGCGCTGTCAGGTGGGGGGCTCCCGGCCACACCG
CTGCTCTTCCACCCCCACACTAAGGGCTCCCAGATCCTCATGGACCTCAGCCACAAGGCCGTCA
AGAGGCAGGCCAGCTTCTGTAATGCCATCACCTTCAGCAACCGCCCCGTCCTCATCTACGAGCA
AGTCAGGCTGAAGATCACCAAGAAGCAGTGCTGCTGGAGCGGGGCCCTGCGACTTGGCTTCACC
AGCAAGGACCCTTCCCGCATCCACCCCGACTCACTGCCCAAGTACGCCTGCCCTGACCTGGTGT
CCCAGAGTGGCTTCTGGGCCAAAGCGTTGCCTGAGGAGTTTGCCAACGAGGGCAACATCATTGC
CTTCTGGGTGGACAAGAAGGGCCGAGTCTTCTACCGGATCAATGAGTCGGCTGCCATGCTGTTC
TTCAGCGGGGTTCGAACGGCGGACCCGCTCTGGGCCCTGGTGGACGTCTACGGCCTCACACGGG
GTGTCCAGCTGCTAGGCACGCAGACTCTACACACAGGCAGAGCCTCGTCAAGCCTCAGCTTCCT
CATCTGGAAAATGGGCCATGGGTAGAGTT

hide sequence

RefSeq Acc Id:

NM_001401624 ⟹ NP_001388553

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,008,160 - 256,094,219 (+)	NCBI
mRatBN7.2	1	246,066,830 - 246,152,888 (+)	NCBI

RefSeq Acc Id:

XM_006231511 ⟹ XP_006231573

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,062,832 - 256,094,219 (+)	NCBI
mRatBN7.2	1	246,121,668 - 246,152,890 (+)	NCBI
Rnor_6.0	1	267,007,685 - 267,038,879 (+)	NCBI
Rnor_5.0	1	274,383,360 - 274,469,446 (+)	NCBI

Sequence:

show sequence

GAGGAGGGGAACTGGCGGTCAGGGCAGCTCGGTGAGGTGACGAGGCTGGCCAGCCAAACGGAGG
TGGCCAAGCTACCAGCAGCCTGAGATGGGGGGACAGATCACAAGGAACACTCTCCACGACTCCA
TCGGGAGCTCCTTCCCGGTCCCCTCTCACCGATGCCATCACAAGCAGAAGCATTGCCCGCCCGC
GCTGTCAGGTGGGGGGCTCCCGGCCACACCGCTGCTCTTCCACCCCCACACTAAGGGCTCCCAG
ATCCTCATGGACCTCAGCCACAAGGCCGTCAAGAGGCAGGCCAGCTTCTGTAATGCCATCACCT
TCAGCAACCGCCCCGTCCTCATCTACGAGCAAGTCAGGCTGAAGATCACCAAGAAGCAGTGCTG
CTGGAGCGGGGCCCTGCGACTTGGCTTCACCAGCAAGGACCCTTCCCGCATCCACCCCGACTCA
CTGCCCAAGTACGCCTGCCCTGACCTGGTGTCCCAGAGTGGCTTCTGGGCCAAAGCGTTGCCTG
AGGAGTTTGCCAACGAGGGCAACATCATTGCCTTCTGGGTGGACAAGAAGGGCCGAGTCTTCTA
CCGGATCAATGAGTCGGCTGCCATGCTGTTCTTCAGCGGGGTTCGAACGGCGGACCCGCTCTGG
GCCCTGGTGGACGTCTACGGCCTCACACGGGGTGTCCAGCTGCTAGACAGCGAGCTGGTGCTGC
CTGACTGCCTGAGGCCGCGCTCCTTCACCGCGCTGCGGCGGCCGTCGCTGCGGTGCGAGGCGGA
CGAGGCGCGCCTGTCTGTGAGCCTGTGCGACCTCAACGTGCCGGGAGCCGACGGCGAGGACGGC
GCACCGCCCGCCGGCTGCCCGATCCCGCAGAACTCGCTCAACTCTCAGCACAGCCGCGCGCTGC
CGGCGCAGCTCGACGGCGACCTGCGCTTCCACGCTCTGCGCGCCGGCGCGCACGTCCGCATCCT
GGACGAGCAAACCGTGGCGCGCCTAGAGCACGGGCGCGACGAGCGCGCGCTCGTCTTCACCAGC
CGGCCGGTGCGCGTGGCCGAGACCATCTTCATCAAGGTCACGCGCTCAGGCGGTGCGCGACCAG
GAGCGCTGTCCTTCGGGGTCACCACGTGTGACCCTGGCACGCTGCGGCCCGCCGACCTGCCCTT
CAGCCCCGAGGCCCTGGTGGACCGCAAGGAGTTCTGGGCGGTGTGTCGCGTGCCTGGGCCTCTG
CACAGTGGTGACATCCTGGGCCTGGTGGTCAATGCGGACGGAGAGCTGCACCTAAGTCACAACG
GCGCGCCGGCCGGCATGCAGCTATGCGTGGACGCCTCGCAGCCCCTCTGGATGCTCTTCAGCCT
GCACGGCGCCATCACGCAGGTCCGCATCCTTGGCTCCACCATCATGGCTGAACGGGGTGGCCCA
TCTCTCCCCTGCTCACCTGCCTCCACTCCAACCTCGCCCAGTGCCCTGGGCAGCCGCCTCTCTG
ACCCCCTGCTCAGCACATGCGGTTCTGGGCCCCTGGGTGGCTCTGCTGGCGGAACAGCCCCCAA
CTCACCTGTGAGCCTGCCCGAGTCACCAGTGACCCCGGGTCTGGGCCAGTGGAGCGATGAATGC
ACCATTTGCTATGAACACGCAGTGGATACAGTCATCTACACGTGTGGCCACATGTGCCTGTGCT
ACTCCTGTGGCCTGCGCCTCAAGAAGGCCCTGCACGCCTGCTGCCCCATCTGCCGTCGCCCCAT
CAAGGACATCATCAAGACCTACCGCAGCTCCTAGCCCACTGCAGAGCCCCACCCGCACGCCCAC
TTCTGCAGACTGCAGCCCAGCACCAGCCGAGGGCAAAGCCAACAGGGTCCCTTCCTTCTACAGT
TTGCAAACTCTCCCTCCTTTGTCCATTAAACATGGGAAACCAAGGTCCCTGAAGGTTTGGGCTG
AGAGGGTCTCAGGCAGGGAGGTGGGGCACAAGTAGTGAACGGAGGGGGGGGAGAAGGGTACCCC
ACCATCTCTCCTCTTTACACAGATTTCTGCATGCTGAGGGGCTGAAGTAGCGTTTCAGCTTGTT
GCCATCCCTCCCGAGCTAGGCAGATTTCTAGGTTGTGCAGCCCGCGTGGCATCTTGGAGAGAGT
TAGCGAACATGTAGCTTCTGGGCAGCTGCAAACTGCATGCCGTGTCTCTTTCTCCTTACCCACA
GCGGGTAGACAGACAGGCTGCAGATCCCAAGTCCTACGTCCTTGACCTCACGTCGACCTGCCAC
GTCCAGGACGCCCCGTTTGCCCTGATTTTCGCCAATCATCTCACTGGTGCCGTTTCCCAGGGTG
CCCTGCGGTAAAGGCTGACTCGGGCCTTTCTGTTGTCGGGGTCTCAAAAGAACAGGTCCACAGT
CACACTTAAGGCCTGCCCTCCCTCATCTCGGCCTGGGCTGGTCTTGCCATCGTTTGCCTGGGAG
GGACAGGACCCTTCGGTGGGGTGGGGGTTTCCTGGCCCATAGACAGCCCCTTTTCCTTATTTTA
ATTTATTTATTTATTTGGTTGATGGGTCTTGTTGATGGGTTATGTTCCAACCTGGGTTCTCCTA
AAATACTGCTGTTGTGCGGGGGGAGGGCTGCCAGGTGAAGGGAAGCAAGGAGTAGCCACCCAGA
ATAATCTGCCCCCAACACAAGGCTCATGGGCAGTCCTGCTCACCCTGAGGTAGAATTCCAGGCT
GGAGGCCTCCCAAGAGGTGGATGAGCCTCTCATGGGTGGGAACCACCCACATCCACCTGTGCCC
TTCCTCTCTGGATTGGAGCTCCATTAGTGTGGCTGGTTCTGATGTCTTTAAGGACATCAGACGT
TCTGGAAGGTTGTCAACATGTGGGTCAGGGACCAGAATAGAGACCCTAGTTAGAAGAGGGAGGA
CGGATCCTGAAAGCCAGGCTCTGCTCCTAAGGGGGTGTCTGCTATTTACGGCCCCCAGTCCTAC
CTGCCTGTTCTGGGTTACTGTGGAGTTGTAGCCTAGGCTTTCCCAGCCTTTCAGTCCTCGGCCC
TCATGGCTGGTTTTATACCCACAGAGGTGACTTCTGCCTTAAGAGGCAAGGTCTGTGTCTCTGT
CCCGGCCACTGGGCAGCCGTGTGGCTCTGACCACAGGTCACCCCCTCCCCCAAACTCCAGCTTC
CCCTGGGTAAAAGTTTGGGGGTGGAACTTTTTCCGTGCAGCTCCTGGGAGTTCTTCTCAGGTCT
CTTCGGAGGAATGTACTGGGGAAGCCTTGAGAATGGATGCCAGGGTAAGCCTTTGCCCACACGG
GGGAGTCTGGGCCACCCCTAGTCTCACCTCTCCAGTCACTGGCCCTGGTAGGTTCTTTCAGGCT
GGAGCTGGCACGTCGAGCTGGGGCTCATCCTAGCGGTGGGGGAAAGGCCCCAGTACAGAGCTGC
GTGGCTGGAGATGGGAAAAGAAGCCATTGTCCATCCTGCTAGTTCAGAGGTAGCATTGCCTCCT
TTGTGAACTGGGTCACTGTGTTTGTGAATAAAGGTGATTTCGTACCAGC

hide sequence

RefSeq Acc Id:

XM_006231512 ⟹ XP_006231574

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,063,768 - 256,094,219 (+)	NCBI
mRatBN7.2	1	246,122,454 - 246,152,890 (+)	NCBI
Rnor_6.0	1	267,007,954 - 267,038,879 (+)	NCBI
Rnor_5.0	1	274,383,360 - 274,469,446 (+)	NCBI

Sequence:

show sequence

TGTGTGTGTAACAGTGGTGGGGTGGTTGGGTGTTTGTCACTGTGACTGGAGAAAGAGGTCTAGG
GAAAGTTAGATGGTCAGATATCTGACTTTCCCTGCAAAGTGGCCTTGTCCTCTTACCAGGTTAT
GGAGCAGCCCCTGAGTGGGATGTGAGGTCCAGGGTATCAGAAATGTACCATTCCCAGTTACTCA
GACAACTGGGGTGACTGTGTGGGTCCTGGAGGTAGTCTGTGAGAGATGTTTGGGTGCCCTGTGT
GTATACACAAGTGTCTGTGCTTGTGAGTTTTCGTTAGAGGGATCTGTGGGTGTGTACTTGTGCC
AGCTTGCGCCTCAGCACACAGGTGTGCTAGACAGGTGTGCTAGTGACAGCCCCCACAGAGCCTG
ACCTGCTTCTCCAAGAGAGGAGAATGAATTTCTGGCAGATCCACAAGCAGGGAGGTGAGGGCGG
GGAAGGAAACATACTGGCTGGCATCCTATTTGCTGGACTCCTGCTTGCTTGCACTCCTGTCTTC
TGGACTGCTGGGCTCGATGGTCTCGGGAACAAGATGGCCAATGTGACAGCAGACCCAAAGGGGA
ACCCTTCCTTAGAAATGGAACTGGGCTCTGCTACAAACTGTGTGGAGTCAGAGTGCCCACCTTG
ATGCCCTGTGACCCCCCCCTAGAAGACTCCATCGGGAGCTCCTTCCCGGTCCCCTCTCACCGAT
GCCATCACAAGCAGAAGCATTGCCCGCCCGCGCTGTCAGGTGGGGGGCTCCCGGCCACACCGCT
GCTCTTCCACCCCCACACTAAGGGCTCCCAGATCCTCATGGACCTCAGCCACAAGGCCGTCAAG
AGGCAGGCCAGCTTCTGTAATGCCATCACCTTCAGCAACCGCCCCGTCCTCATCTACGAGCAAG
TCAGGCTGAAGATCACCAAGAAGCAGTGCTGCTGGAGCGGGGCCCTGCGACTTGGCTTCACCAG
CAAGGACCCTTCCCGCATCCACCCCGACTCACTGCCCAAGTACGCCTGCCCTGACCTGGTGTCC
CAGAGTGGCTTCTGGGCCAAAGCGTTGCCTGAGGAGTTTGCCAACGAGGGCAACATCATTGCCT
TCTGGGTGGACAAGAAGGGCCGAGTCTTCTACCGGATCAATGAGTCGGCTGCCATGCTGTTCTT
CAGCGGGGTTCGAACGGCGGACCCGCTCTGGGCCCTGGTGGACGTCTACGGCCTCACACGGGGT
GTCCAGCTGCTAGACAGCGAGCTGGTGCTGCCTGACTGCCTGAGGCCGCGCTCCTTCACCGCGC
TGCGGCGGCCGTCGCTGCGGTGCGAGGCGGACGAGGCGCGCCTGTCTGTGAGCCTGTGCGACCT
CAACGTGCCGGGAGCCGACGGCGAGGACGGCGCACCGCCCGCCGGCTGCCCGATCCCGCAGAAC
TCGCTCAACTCTCAGCACAGCCGCGCGCTGCCGGCGCAGCTCGACGGCGACCTGCGCTTCCACG
CTCTGCGCGCCGGCGCGCACGTCCGCATCCTGGACGAGCAAACCGTGGCGCGCCTAGAGCACGG
GCGCGACGAGCGCGCGCTCGTCTTCACCAGCCGGCCGGTGCGCGTGGCCGAGACCATCTTCATC
AAGGTCACGCGCTCAGGCGGTGCGCGACCAGGAGCGCTGTCCTTCGGGGTCACCACGTGTGACC
CTGGCACGCTGCGGCCCGCCGACCTGCCCTTCAGCCCCGAGGCCCTGGTGGACCGCAAGGAGTT
CTGGGCGGTGTGTCGCGTGCCTGGGCCTCTGCACAGTGGTGACATCCTGGGCCTGGTGGTCAAT
GCGGACGGAGAGCTGCACCTAAGTCACAACGGCGCGCCGGCCGGCATGCAGCTATGCGTGGACG
CCTCGCAGCCCCTCTGGATGCTCTTCAGCCTGCACGGCGCCATCACGCAGGTCCGCATCCTTGG
CTCCACCATCATGGCTGAACGGGGTGGCCCATCTCTCCCCTGCTCACCTGCCTCCACTCCAACC
TCGCCCAGTGCCCTGGGCAGCCGCCTCTCTGACCCCCTGCTCAGCACATGCGGTTCTGGGCCCC
TGGGTGGCTCTGCTGGCGGAACAGCCCCCAACTCACCTGTGAGCCTGCCCGAGTCACCAGTGAC
CCCGGGTCTGGGCCAGTGGAGCGATGAATGCACCATTTGCTATGAACACGCAGTGGATACAGTC
ATCTACACGTGTGGCCACATGTGCCTGTGCTACTCCTGTGGCCTGCGCCTCAAGAAGGCCCTGC
ACGCCTGCTGCCCCATCTGCCGTCGCCCCATCAAGGACATCATCAAGACCTACCGCAGCTCCTA
GCCCACTGCAGAGCCCCACCCGCACGCCCACTTCTGCAGACTGCAGCCCAGCACCAGCCGAGGG
CAAAGCCAACAGGGTCCCTTCCTTCTACAGTTTGCAAACTCTCCCTCCTTTGTCCATTAAACAT
GGGAAACCAAGGTCCCTGAAGGTTTGGGCTGAGAGGGTCTCAGGCAGGGAGGTGGGGCACAAGT
AGTGAACGGAGGGGGGGGAGAAGGGTACCCCACCATCTCTCCTCTTTACACAGATTTCTGCATG
CTGAGGGGCTGAAGTAGCGTTTCAGCTTGTTGCCATCCCTCCCGAGCTAGGCAGATTTCTAGGT
TGTGCAGCCCGCGTGGCATCTTGGAGAGAGTTAGCGAACATGTAGCTTCTGGGCAGCTGCAAAC
TGCATGCCGTGTCTCTTTCTCCTTACCCACAGCGGGTAGACAGACAGGCTGCAGATCCCAAGTC
CTACGTCCTTGACCTCACGTCGACCTGCCACGTCCAGGACGCCCCGTTTGCCCTGATTTTCGCC
AATCATCTCACTGGTGCCGTTTCCCAGGGTGCCCTGCGGTAAAGGCTGACTCGGGCCTTTCTGT
TGTCGGGGTCTCAAAAGAACAGGTCCACAGTCACACTTAAGGCCTGCCCTCCCTCATCTCGGCC
TGGGCTGGTCTTGCCATCGTTTGCCTGGGAGGGACAGGACCCTTCGGTGGGGTGGGGGTTTCCT
GGCCCATAGACAGCCCCTTTTCCTTATTTTAATTTATTTATTTATTTGGTTGATGGGTCTTGTT
GATGGGTTATGTTCCAACCTGGGTTCTCCTAAAATACTGCTGTTGTGCGGGGGGAGGGCTGCCA
GGTGAAGGGAAGCAAGGAGTAGCCACCCAGAATAATCTGCCCCCAACACAAGGCTCATGGGCAG
TCCTGCTCACCCTGAGGTAGAATTCCAGGCTGGAGGCCTCCCAAGAGGTGGATGAGCCTCTCAT
GGGTGGGAACCACCCACATCCACCTGTGCCCTTCCTCTCTGGATTGGAGCTCCATTAGTGTGGC
TGGTTCTGATGTCTTTAAGGACATCAGACGTTCTGGAAGGTTGTCAACATGTGGGTCAGGGACC
AGAATAGAGACCCTAGTTAGAAGAGGGAGGACGGATCCTGAAAGCCAGGCTCTGCTCCTAAGGG
GGTGTCTGCTATTTACGGCCCCCAGTCCTACCTGCCTGTTCTGGGTTACTGTGGAGTTGTAGCC
TAGGCTTTCCCAGCCTTTCAGTCCTCGGCCCTCATGGCTGGTTTTATACCCACAGAGGTGACTT
CTGCCTTAAGAGGCAAGGTCTGTGTCTCTGTCCCGGCCACTGGGCAGCCGTGTGGCTCTGACCA
CAGGTCACCCCCTCCCCCAAACTCCAGCTTCCCCTGGGTAAAAGTTTGGGGGTGGAACTTTTTC
CGTGCAGCTCCTGGGAGTTCTTCTCAGGTCTCTTCGGAGGAATGTACTGGGGAAGCCTTGAGAA
TGGATGCCAGGGTAAGCCTTTGCCCACACGGGGGAGTCTGGGCCACCCCTAGTCTCACCTCTCC
AGTCACTGGCCCTGGTAGGTTCTTTCAGGCTGGAGCTGGCACGTCGAGCTGGGGCTCATCCTAG
CGGTGGGGGAAAGGCCCCAGTACAGAGCTGCGTGGCTGGAGATGGGAAAAGAAGCCATTGTCCA
TCCTGCTAGTTCAGAGGTAGCATTGCCTCCTTTGTGAACTGGGTCACTGTGTTTGTGAATAAAG
GTGATTTCGTACCAGC

hide sequence

RefSeq Acc Id:

XM_063265076 ⟹ XP_063121146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,008,012 - 256,094,219 (+)	NCBI

RefSeq Acc Id:

XM_063265078 ⟹ XP_063121148

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,062,878 - 256,094,219 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101075	(Get FASTA)	NCBI Sequence Viewer
	NP_001388553	(Get FASTA)	NCBI Sequence Viewer
	XP_006231573	(Get FASTA)	NCBI Sequence Viewer
	XP_006231574	(Get FASTA)	NCBI Sequence Viewer
	XP_063121146	(Get FASTA)	NCBI Sequence Viewer
	XP_063121148	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL94375	(Get FASTA)	NCBI Sequence Viewer
	EDL94376	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051580
	ENSRNOP00000051580.2
	ENSRNOP00000068189
	ENSRNOP00000068189.2
	ENSRNOP00000079455
	ENSRNOP00000079455.1
	ENSRNOP00000103765
	ENSRNOP00000103765.1
	ENSRNOP00000106458
	ENSRNOP00000106458.1

RefSeq Acc Id:	NP_001101075 ⟸ NM_001107605
- Peptide Label:	isoform 2
- UniProtKB:	D3ZZE6 (UniProtKB/TrEMBL), A6JHQ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNNFSSVSSLQRGNPSRASRGHPQNLKDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLL FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSK DPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFS GVRTADPLWALVDVYGLTRGVQLLGTQTLHTGRASSSLSFLIWKMGHG hide sequence

RefSeq Acc Id:	XP_006231573 ⟸ XM_006231511
- Peptide Label:	isoform X1
- UniProtKB:	A0A096MJM7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGQITRNTLHDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLLFHPHTKGSQILMDLSHK AVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPD LVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTADPLWALVDVYGL TRGVQLLDSELVLPDCLRPRSFTALRRPSLRCEADEARLSVSLCDLNVPGADGEDGAPPAGCPI PQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARLEHGRDERALVFTSRPVRVAET IFIKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGL VVNADGELHLSHNGAPAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMAERGGPSLPCSPAS TPTSPSALGSRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAV DTVIYTCGHMCLCYSCGLRLKKALHACCPICRRPIKDIIKTYRSS hide sequence

RefSeq Acc Id:

XP_006231574 ⟸ XM_006231512

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPCDPPLEDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLLFHPHTKGSQILMDLSHKAVK
RQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVS
QSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTADPLWALVDVYGLTRG
VQLLDSELVLPDCLRPRSFTALRRPSLRCEADEARLSVSLCDLNVPGADGEDGAPPAGCPIPQN
SLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARLEHGRDERALVFTSRPVRVAETIFI
KVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVN
ADGELHLSHNGAPAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMAERGGPSLPCSPASTPT
SPSALGSRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTV
IYTCGHMCLCYSCGLRLKKALHACCPICRRPIKDIIKTYRSS

hide sequence

Ensembl Acc Id:

ENSRNOP00000051580 ⟸ ENSRNOT00000054696

Ensembl Acc Id:

ENSRNOP00000068189 ⟸ ENSRNOT00000076452

Ensembl Acc Id:

ENSRNOP00000079455 ⟸ ENSRNOT00000112299

RefSeq Acc Id:	NP_001388553 ⟸ NM_001401624
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5ZN22 (UniProtKB/TrEMBL), A6JHQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121146 ⟸ XM_063265076
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063121148 ⟸ XM_063265078
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSRNOP00000106458 ⟸ ENSRNOT00000129899

Ensembl Acc Id:

ENSRNOP00000103765 ⟸ ENSRNOT00000165645

Protein Domains

NHR RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A096MJM7-F1-model_v2	AlphaFold	A0A096MJM7	1-574	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690978

Promoter ID:

EPDNEW_R1502

Type:

multiple initiation site

Name:

Neurl1_1

Description:

neuralized E3 ubiquitin protein ligase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	266,952,910 - 266,952,970	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307021	AgrOrtholog
BioCyc Gene	G2FUF-55486	BioCyc
Ensembl Genes	ENSRNOG00000020339	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000054696	ENTREZGENE
	ENSRNOT00000054696.4	UniProtKB/TrEMBL
	ENSRNOT00000076452	ENTREZGENE
	ENSRNOT00000076452.4	UniProtKB/TrEMBL
	ENSRNOT00000112299	ENTREZGENE
	ENSRNOT00000112299.2	UniProtKB/TrEMBL
	ENSRNOT00000129899	ENTREZGENE
	ENSRNOT00000129899.1	UniProtKB/TrEMBL
	ENSRNOT00000165645	ENTREZGENE
	ENSRNOT00000165645.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	B30.2/SPRY_sf	UniProtKB/TrEMBL
	Neu_Z	UniProtKB/TrEMBL
	Neuralized	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
NCBI Gene	309459	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE NEURL1	UniProtKB/TrEMBL
	PTHR12429	UniProtKB/TrEMBL
Pfam	Neuralized	UniProtKB/TrEMBL
	zf-C3HC4_3	UniProtKB/TrEMBL
PhenoGen	Neurl1	PhenoGen
PROSITE	NHR	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020339	RatGTEx
SMART	NEUZ	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A096MJM7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZN22	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LHD6_RAT	UniProtKB/TrEMBL
	A0ABK0LN89_RAT	UniProtKB/TrEMBL
	A6JHQ1	ENTREZGENE, UniProtKB/TrEMBL
	A6JHQ2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZE6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-11-19	Neurl1	neuralized E3 ubiquitin protein ligase 1	Neurl1a	neuralized homolog 1A (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-03-26	Neurl1a	neuralized homolog 1A (Drosophila)	Neurl	neuralized homolog (Drosophila)	Name and Symbol changed	629549	APPROVED
2008-09-25	Neurl	neuralized homolog (Drosophila)	Neurl	neuralized-like homolog (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Neurl	neuralized-like homolog (Drosophila)	Neurl_predicted	neuralized-like (Drosophila) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Neurl_predicted	neuralized-like (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

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Imported Disease Annotations - CTD

RGD Manual Annotations