NEURL1 (neuralized E3 ubiquitin protein ligase 1) - Rat Genome Database

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Gene: NEURL1 (neuralized E3 ubiquitin protein ligase 1) Pan paniscus
Analyze
Symbol: NEURL1
Name: neuralized E3 ubiquitin protein ligase 1
RGD ID: 11972375
Description: ENCODES a protein that exhibits translation factor activity, non-nucleic acid binding (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN flagellated sperm motility (ortholog); lactation (ortholog); negative regulation of cell population proliferation (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Colorectal Neoplasms (ortholog); desmoplastic/nodular medulloblastoma (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase NEURL1; neuralized homolog; NEURL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28115,380,176 - 115,477,017 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110115,385,505 - 115,482,346 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,093,614 - 100,192,485 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110103,554,939 - 103,653,928 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NEURL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28115,380,176 - 115,477,017 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110115,385,505 - 115,482,346 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,093,614 - 100,192,485 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110103,554,939 - 103,653,928 (+)NCBIpanpan1.1PanPan1.1panPan2
NEURL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810103,493,705 - 103,592,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10103,493,705 - 103,592,546 (+)EnsemblGRCh38hg38GRCh38
GRCh3710105,253,462 - 105,352,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610105,244,038 - 105,342,293 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410105,244,037 - 105,342,292NCBI
Celera1098,993,672 - 99,092,247 (+)NCBICelera
Cytogenetic Map10q24.33NCBI
HuRef1098,884,519 - 99,014,405 (+)NCBIHuRef
CHM1_110105,537,848 - 105,636,430 (+)NCBICHM1_1
T2T-CHM13v2.010104,381,009 - 104,479,861 (+)NCBIT2T-CHM13v2.0
Neurl1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,167,259 - 47,247,880 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,167,259 - 47,247,880 (+)EnsemblGRCm39 Ensembl
GRCm381947,178,820 - 47,259,441 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,178,820 - 47,259,441 (+)EnsemblGRCm38mm10GRCm38
MGSCv371947,253,310 - 47,333,931 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,232,131 - 47,312,752 (+)NCBIMGSCv36mm8
Celera1947,936,911 - 48,016,141 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1939.39NCBI
Neurl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,008,012 - 256,094,219 (+)NCBIGRCr8
mRatBN7.21246,066,830 - 246,152,890 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,067,100 - 246,152,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,193,488 - 254,279,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,887,323 - 260,973,172 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,535,819 - 253,621,537 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01266,953,006 - 267,038,879 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,952,561 - 267,038,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01274,383,360 - 274,469,446 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41252,502,664 - 252,573,249 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11252,767,229 - 252,856,359 (+)NCBI
Celera1241,838,929 - 241,904,988 (+)NCBICelera
Cytogenetic Map1q54NCBI
Neurl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554857,015,969 - 7,046,089 (-)NCBIChiLan1.0ChiLan1.0
NEURL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,856,494 - 15,935,897 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,856,616 - 15,933,763 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2816,028,329 - 16,107,610 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02816,332,801 - 16,412,233 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2816,332,895 - 16,412,228 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12815,881,613 - 15,960,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02815,909,624 - 15,988,946 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02816,048,129 - 16,127,416 (+)NCBIUU_Cfam_GSD_1.0
Neurl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721330,916,638 - 30,987,111 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366002,518,265 - 2,590,344 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366002,518,193 - 2,590,336 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEURL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14114,437,045 - 114,516,721 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114114,436,887 - 114,515,713 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214124,318,621 - 124,395,945 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEURL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1996,542,046 - 96,641,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl996,542,473 - 96,639,761 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604857,658,166 - 57,766,031 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Neurl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248312,717,226 - 2,778,977 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248312,717,184 - 2,778,907 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_034931427   ⟹   XP_034787318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28115,380,176 - 115,477,017 (+)NCBI
NHGRI_mPanPan110115,385,505 - 115,482,346 (+)NCBI
Mhudiblu_PPA_v010100,093,614 - 100,192,485 (+)NCBI
RefSeq Acc Id: XM_034931428   ⟹   XP_034787319
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28115,441,727 - 115,477,017 (+)NCBI
NHGRI_mPanPan110115,447,056 - 115,482,346 (+)NCBI
Mhudiblu_PPA_v010100,155,094 - 100,192,485 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034787318 (Get FASTA)   NCBI Sequence Viewer  
  XP_034787319 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024846.1
Reference Protein Sequences
RefSeq Acc Id: XP_034787318   ⟸   XM_034931427
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034787319   ⟸   XM_034931428
- Peptide Label: isoform X2
Protein Domains
NHR   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035559 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047672.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY_sf UniProtKB/TrEMBL
  Neuralized UniProtKB/TrEMBL
  NHR_dom UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene NEURL1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE NEURL1 UniProtKB/TrEMBL
  PTHR12429 UniProtKB/TrEMBL
Pfam Neuralized UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
PROSITE NHR UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART NEUZ UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A2R9B706_PANPA UniProtKB/TrEMBL