Klf11 (KLF transcription factor 11) - Rat Genome Database

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Gene: Klf11 (KLF transcription factor 11) Rattus norvegicus
Analyze
Symbol: Klf11
Name: KLF transcription factor 11
RGD ID: 1306646
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to endothelin. Predicted to be located in cytosol; focal adhesion; and nuclear body. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Orthologous to human KLF11 (KLF transcription factor 11); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Krueppel-like factor 11; Kruppel-like factor 11; LOC313994; Tcfcp2l2; transcription factor CP2-like 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8647,014,312 - 47,026,152 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl647,014,326 - 47,037,044 (+)EnsemblGRCr8
mRatBN7.2641,285,699 - 41,297,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl641,285,842 - 41,297,550 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx641,608,755 - 41,620,386 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,923,562 - 41,935,193 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0641,356,708 - 41,368,339 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,829,812 - 43,841,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,829,945 - 43,841,651 (+)Ensemblrn6Rnor6.0
Rnor_5.0660,701,310 - 60,724,151 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4642,296,221 - 42,307,925 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera640,573,522 - 40,585,226 (+)NCBICelera
RGSC_v3.1642,283,152 - 42,309,011 (+)NCBI
Cytogenetic Map6q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-naphthylamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
fenofibrate  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
indometacin  (ISO)
ketoconazole  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propionic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Differential regulation of Kruppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Cullingford TE, etal., Biochim Biophys Acta. 2008 Jun;1783(6):1229-36. Epub 2008 Mar 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C. Gutierrez-Aguilar R, etal., J Clin Endocrinol Metab. 2008 Aug;93(8):3128-35. Epub 2008 May 27.
4. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Neve B, etal., Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4807-12. Epub 2005 Mar 17.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:14697507   PMID:15607700   PMID:21171965   PMID:21592955   PMID:25739536   PMID:27848055  


Genomics

Comparative Map Data
Klf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8647,014,312 - 47,026,152 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl647,014,326 - 47,037,044 (+)EnsemblGRCr8
mRatBN7.2641,285,699 - 41,297,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl641,285,842 - 41,297,550 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx641,608,755 - 41,620,386 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,923,562 - 41,935,193 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0641,356,708 - 41,368,339 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,829,812 - 43,841,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,829,945 - 43,841,651 (+)Ensemblrn6Rnor6.0
Rnor_5.0660,701,310 - 60,724,151 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4642,296,221 - 42,307,925 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera640,573,522 - 40,585,226 (+)NCBICelera
RGSC_v3.1642,283,152 - 42,309,011 (+)NCBI
Cytogenetic Map6q16NCBI
KLF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38210,043,550 - 10,054,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl210,042,849 - 10,054,836 (+)Ensemblhg38GRCh38
GRCh37210,183,677 - 10,194,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36210,101,133 - 10,112,414 (+)NCBIBuild 36Build 36hg18NCBI36
Celera210,100,586 - 10,111,182 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef210,036,117 - 10,046,713 (+)NCBIHuRef
CHM1_1210,113,564 - 10,124,797 (+)NCBICHM1_1
T2T-CHM13v2.0210,072,326 - 10,083,576 (+)NCBIT2T-CHM13v2.0
Klf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391224,701,370 - 24,712,781 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1224,701,273 - 24,712,788 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381224,651,371 - 24,662,782 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1224,651,274 - 24,662,789 (+)Ensemblmm10GRCm38
MGSCv371225,336,236 - 25,347,647 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361225,240,353 - 25,251,754 (+)NCBIMGSCv36mm8
Celera1226,112,243 - 26,123,694 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.49NCBI
Klf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554875,448,869 - 5,454,322 (+)NCBIChiLan1.0ChiLan1.0
KLF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,464,993 - 116,489,347 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,468,964 - 116,493,324 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A10,027,152 - 10,051,445 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A10,185,034 - 10,208,220 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A10,195,564 - 10,208,220 (+)EnsemblpanPan2panpan1.1
KLF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1177,038,282 - 7,049,880 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl177,010,313 - 7,049,426 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha176,965,333 - 6,976,823 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0177,136,573 - 7,148,112 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,139,227 - 7,145,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1177,028,519 - 7,040,002 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0177,030,745 - 7,042,292 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0177,044,796 - 7,056,291 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,526,321 - 51,534,846 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365326,282,313 - 6,290,569 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,418,996 - 126,429,897 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13126,419,011 - 126,429,890 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KLF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11497,574,930 - 97,586,398 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1497,573,555 - 97,586,256 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604514,725,977 - 14,737,662 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klf11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248655,023,074 - 5,031,347 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Klf11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1738,263,422 - 38,275,157 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Klf11
88 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:551
Count of miRNA genes:281
Interacting mature miRNAs:346
Transcripts:ENSRNOT00000000231
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)64005241156848866Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat

Markers in Region
RH143885  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2641,297,114 - 41,297,292 (+)MAPPERmRatBN7.2
Rnor_6.0643,841,216 - 43,841,393NCBIRnor6.0
Rnor_5.0660,712,699 - 60,712,876UniSTSRnor5.0
RGSC_v3.4642,307,492 - 42,307,669UniSTSRGSC3.4
Celera640,584,793 - 40,584,970UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000086548   ⟹   ENSRNOP00000075389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl647,014,326 - 47,026,158 (+)Ensembl
mRatBN7.2 Ensembl641,285,842 - 41,297,550 (+)Ensembl
Rnor_6.0 Ensembl643,829,945 - 43,841,651 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150089   ⟹   ENSRNOP00000102673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl647,014,928 - 47,026,158 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157225   ⟹   ENSRNOP00000102722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl647,014,326 - 47,037,044 (+)Ensembl
RefSeq Acc Id: NM_001037354   ⟹   NP_001032431
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8647,014,448 - 47,026,152 (+)NCBI
mRatBN7.2641,285,842 - 41,297,548 (+)NCBI
Rnor_6.0643,829,945 - 43,841,649 (+)NCBI
Rnor_5.0660,701,310 - 60,724,151 (+)NCBI
RGSC_v3.4642,296,221 - 42,307,925 (+)RGD
Celera640,573,522 - 40,585,226 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239984   ⟹   XP_006240046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8647,014,313 - 47,022,275 (+)NCBI
mRatBN7.2641,285,699 - 41,293,460 (+)NCBI
Rnor_6.0643,829,812 - 43,837,498 (+)NCBI
Rnor_5.0660,701,310 - 60,724,151 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354724
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8647,014,312 - 47,023,783 (+)NCBI
mRatBN7.2641,285,699 - 41,295,178 (+)NCBI
Rnor_6.0643,829,812 - 43,839,228 (+)NCBI
Rnor_5.0660,701,310 - 60,724,151 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001032431 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240046 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB29451 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075389
  ENSRNOP00000075389.1
  ENSRNOP00000102673.1
  ENSRNOP00000102722
  ENSRNOP00000102722.1
RefSeq Acc Id: NP_001032431   ⟸   NM_001037354
- UniProtKB: E9PTS6 (UniProtKB/TrEMBL),   Q309C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240046   ⟸   XM_006239984
- Peptide Label: isoform X1
- UniProtKB: Q309C9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075389   ⟸   ENSRNOT00000086548
Ensembl Acc Id: ENSRNOP00000102673   ⟸   ENSRNOT00000150089
Ensembl Acc Id: ENSRNOP00000102722   ⟸   ENSRNOT00000157225
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PTS6-F1-model_v2 AlphaFold E9PTS6 1-501 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694521
Promoter ID:EPDNEW_R5044
Type:multiple initiation site
Name:Klf11_1
Description:Kruppel-like factor 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0643,829,860 - 43,829,920EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306646 AgrOrtholog
BioCyc Gene G2FUF-38025 BioCyc
Ensembl Genes ENSRNOG00000054259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086548 ENTREZGENE
  ENSRNOT00000086548.3 UniProtKB/TrEMBL
  ENSRNOT00000150089.1 UniProtKB/TrEMBL
  ENSRNOT00000157225 ENTREZGENE
  ENSRNOT00000157225.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:313994 UniProtKB/TrEMBL
NCBI Gene 313994 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 11 UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Klf11 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054259 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0ABK0LDH8_RAT UniProtKB/TrEMBL
  A0ABK0LLC6_RAT UniProtKB/TrEMBL
  E9PTS6 ENTREZGENE, UniProtKB/TrEMBL
  Q309C9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-03 Klf11  KLF transcription factor 11  Klf11  Kruppel-like factor 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tcfcp2l2  transcription factor CP2-like 2  Tcfcp2l2_predicted  transcription factor CP2-like 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tcfcp2l2_predicted  transcription factor CP2-like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED