Rpl36a (ribosomal protein L36A) - Rat Genome Database

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Gene: Rpl36a (ribosomal protein L36A) Rattus norvegicus
Analyze
Symbol: Rpl36a
Name: ribosomal protein L36A
RGD ID: 1306640
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL36A (ribosomal protein L36a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 60S ribosomal protein L36a; 60S ribosomal protein L44; large ribosomal subunit protein eL42; LOC292964; MGC188784
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rpl36al-ps1   Rpl36al-ps2   Rpl36al-ps4   Rpl36al-ps5  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,058,573 - 102,062,162 (+)NCBIGRCr8
mRatBN7.2X97,766,179 - 97,768,892 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,766,179 - 97,768,892 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,440,394 - 99,443,107 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02146,639,518 - 146,639,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,453,543 - 100,456,256 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,402,867 - 105,405,580 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,402,867 - 105,405,580 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,292,221 - 105,294,934 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X122,041,847 - 122,044,560 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X122,115,317 - 122,117,940 (+)NCBI
CeleraX98,806,721 - 98,809,434 (+)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, etal., J Biol Chem. 1977 Jun 10;252(11):3961-9.
Additional References at PubMed
PMID:3396452   PMID:12477932   PMID:12962325   PMID:15489334   PMID:22681889   PMID:25957688  


Genomics

Comparative Map Data
Rpl36a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,058,573 - 102,062,162 (+)NCBIGRCr8
mRatBN7.2X97,766,179 - 97,768,892 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,766,179 - 97,768,892 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,440,394 - 99,443,107 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02146,639,518 - 146,639,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,453,543 - 100,456,256 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,402,867 - 105,405,580 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,402,867 - 105,405,580 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,292,221 - 105,294,934 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X122,041,847 - 122,044,560 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X122,115,317 - 122,117,940 (+)NCBI
CeleraX98,806,721 - 98,809,434 (+)NCBICelera
Cytogenetic MapXq32NCBI
RPL36A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,391,011 - 101,396,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,390,824 - 101,396,155 (+)EnsemblGRCh38hg38GRCh38
GRCh37X100,645,999 - 100,651,143 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,532,604 - 100,537,439 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X100,452,088 - 100,457,068NCBI
CeleraX101,165,405 - 101,170,242 (+)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,452,171 - 90,457,437 (+)NCBIHuRef
CHM1_1X100,539,358 - 100,544,623 (+)NCBICHM1_1
T2T-CHM13v2.0X99,835,123 - 99,840,269 (+)NCBIT2T-CHM13v2.0
Rpl36a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,486,403 - 133,488,811 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,486,403 - 133,488,811 (+)EnsemblGRCm39 Ensembl
GRCm38X134,585,654 - 134,588,062 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,585,654 - 134,588,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X131,120,193 - 131,122,601 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,932,035 - 129,934,410 (+)NCBIMGSCv36mm8
CeleraX117,465,238 - 117,467,646 (+)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.2NCBI
Rpl36a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555037,520,530 - 7,523,593 (+)NCBIChiLan1.0ChiLan1.0
RPL36A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,990,209 - 100,995,146 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,993,869 - 100,998,751 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,593,495 - 90,598,380 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,725,528 - 100,730,507 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,725,528 - 100,730,505 (+)Ensemblpanpan1.1panPan2
LOC102155800
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11752,628,292 - 52,628,713 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1752,275,569 - 52,275,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01753,506,340 - 53,506,753 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11752,540,344 - 52,540,757 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01752,582,823 - 52,583,236 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01753,155,905 - 53,156,319 (-)NCBIUU_Cfam_GSD_1.0
Rpl36a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,004,438 - 63,007,625 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936813467,505 - 470,673 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103232362
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,731,684 - 89,736,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,731,725 - 89,736,338 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,651,257 - 14,656,032 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Rpl36a
9 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:175
Count of miRNA genes:121
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000057222
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat

Markers in Region
RH140281  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X97,768,844 - 97,768,996 (+)MAPPERmRatBN7.2
Rnor_6.0X105,405,533 - 105,405,684NCBIRnor6.0
Rnor_5.0X105,294,887 - 105,295,038UniSTSRnor5.0
RGSC_v3.4X122,044,513 - 122,044,664UniSTSRGSC3.4
CeleraX98,809,387 - 98,809,538UniSTS
Cytogenetic MapXq34UniSTS
RH130891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X97,769,026 - 97,769,213 (+)MAPPERmRatBN7.2
Rnor_6.0X105,405,715 - 105,405,901NCBIRnor6.0
Rnor_5.0X105,295,069 - 105,295,255UniSTSRnor5.0
RGSC_v3.4X122,044,695 - 122,044,881UniSTSRGSC3.4
CeleraX98,809,569 - 98,809,755UniSTS
RH 3.4 Map1942.6UniSTS
Cytogenetic MapXq34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 2 1 2
Medium 7 86 112 80 39 80 16 22 148 70 82 23 16
Low 2 3 3 3 1 3 3 3 2 3 2
Below cutoff 1 4

Sequence


RefSeq Acc Id: ENSRNOT00000057222   ⟹   ENSRNOP00000054048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,766,179 - 97,768,892 (+)Ensembl
Rnor_6.0 EnsemblX105,402,867 - 105,405,580 (+)Ensembl
RefSeq Acc Id: NM_001128065   ⟹   NP_001121537
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,059,449 - 102,062,162 (+)NCBI
mRatBN7.2X97,766,179 - 97,768,892 (+)NCBI
Rnor_6.0X105,402,867 - 105,405,580 (+)NCBI
Rnor_5.0X105,292,221 - 105,294,934 (+)NCBI
RGSC_v3.4X122,041,847 - 122,044,560 (+)RGD
CeleraX98,806,721 - 98,809,434 (+)RGD
Sequence:
RefSeq Acc Id: XM_063279829   ⟹   XP_063135899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,059,492 - 102,061,909 (+)NCBI
RefSeq Acc Id: XM_063279830   ⟹   XP_063135900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,059,492 - 102,061,909 (+)NCBI
RefSeq Acc Id: XM_063279831   ⟹   XP_063135901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,058,573 - 102,061,909 (+)NCBI
RefSeq Acc Id: NP_001121537   ⟸   NM_001128065
- UniProtKB: P83883 (UniProtKB/Swiss-Prot),   B2RYQ8 (UniProtKB/TrEMBL),   F8WFR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054048   ⟸   ENSRNOT00000057222
RefSeq Acc Id: XP_063135901   ⟸   XM_063279831
- Peptide Label: isoform X3
- UniProtKB: F8WFR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135899   ⟸   XM_063279829
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135900   ⟸   XM_063279830
- Peptide Label: isoform X2
- UniProtKB: F8WFR5 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P83883-F1-model_v2 AlphaFold P83883 1-106 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701934
Promoter ID:EPDNEW_R12458
Type:multiple initiation site
Name:Rpl36al_1
Description:ribosomal protein L36a-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X105,402,886 - 105,402,946EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306640 AgrOrtholog
BioCyc Gene G2FUF-1681 BioCyc
Ensembl Genes ENSRNOG00000011494 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000031315 UniProtKB/Swiss-Prot
  ENSRNOG00000032408 UniProtKB/TrEMBL
  ENSRNOG00055009019 UniProtKB/Swiss-Prot
  ENSRNOG00055014355 UniProtKB/Swiss-Prot
  ENSRNOG00055032988 UniProtKB/Swiss-Prot
  ENSRNOG00060005818 UniProtKB/Swiss-Prot
  ENSRNOG00060020513 UniProtKB/Swiss-Prot
  ENSRNOG00060032001 UniProtKB/Swiss-Prot
  ENSRNOG00065006379 UniProtKB/Swiss-Prot
  ENSRNOG00065006637 UniProtKB/Swiss-Prot
  ENSRNOG00065030144 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000043171.3 UniProtKB/Swiss-Prot
  ENSRNOT00000047773.5 UniProtKB/TrEMBL
  ENSRNOT00000057222 ENTREZGENE
  ENSRNOT00000057222.3 UniProtKB/Swiss-Prot
  ENSRNOT00055015242 UniProtKB/Swiss-Prot
  ENSRNOT00055024630 UniProtKB/Swiss-Prot
  ENSRNOT00055057047 UniProtKB/Swiss-Prot
  ENSRNOT00060009642 UniProtKB/Swiss-Prot
  ENSRNOT00060035519 UniProtKB/Swiss-Prot
  ENSRNOT00060055473 UniProtKB/Swiss-Prot
  ENSRNOT00065009800 UniProtKB/Swiss-Prot
  ENSRNOT00065010254 UniProtKB/Swiss-Prot
  ENSRNOT00065052019 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.450.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ribosomal_L44e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_zn-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:292964 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:365560 UniProtKB/TrEMBL
  rno:81769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 292964 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L36A UniProtKB/Swiss-Prot
  60S RIBOSOMAL PROTEIN L36A UniProtKB/TrEMBL
  60S RIBOSOMAL PROTEIN L36A UniProtKB/TrEMBL
  PTHR10369 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L44 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpl36a PhenoGen
PROSITE RIBOSOMAL_L44E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011494 RatGTEx
  ENSRNOG00000031315 RatGTEx
  ENSRNOG00000032408 RatGTEx
  ENSRNOG00055009019 RatGTEx
  ENSRNOG00055014355 RatGTEx
  ENSRNOG00055032988 RatGTEx
  ENSRNOG00060005818 RatGTEx
  ENSRNOG00060020513 RatGTEx
  ENSRNOG00060032001 RatGTEx
  ENSRNOG00065006379 RatGTEx
  ENSRNOG00065006637 RatGTEx
  ENSRNOG00065030144 RatGTEx
Superfamily-SCOP SSF57829 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RYQ8 ENTREZGENE, UniProtKB/TrEMBL
  F8WFR5 ENTREZGENE, UniProtKB/TrEMBL
  P83883 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P09896 UniProtKB/Swiss-Prot
  P10661 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-07 Rpl36a  ribosomal protein L36A  Rpl36a  ribosomal protein L36a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rpl36a  ribosomal protein L36a   Rpl36a_predicted  ribosomal protein L36a (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rpl36a_predicted  ribosomal protein L36a (predicted)      Symbol and Name status set to approved 70820 APPROVED