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Gene: Lrrc8c (leucine rich repeat containing 8 VRAC subunit C) Rattus norvegicus

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Symbol:

Lrrc8c

Name:

leucine rich repeat containing 8 VRAC subunit C

RGD ID:

1306585

Description:

Contributes to volume-sensitive anion channel activity. Involved in aspartate transmembrane transport; cellular response to osmotic stress; and taurine transmembrane transport. Part of monoatomic ion channel complex. Orthologous to human LRRC8C (leucine rich repeat containing 8 VRAC subunit C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

leucine rich repeat containing 8 family, member C; leucine-rich repeat-containing protein 8C; LOC289443; MGC112653; RGD1306585; similar to hypothetical protein AD158; volume-regulated anion channel subunit LRRC8C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	4,528,721 - 4,621,259 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	4,531,823 - 4,620,049 (-)	Ensembl				GRCr8
mRatBN7.2	14	4,223,901 - 4,315,590 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	4,227,832 - 4,315,249 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	4,224,741 - 4,312,023 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	5,524,900 - 5,612,184 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	4,230,446 - 4,317,709 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	5,283,655 - 5,378,738 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	5,283,647 - 5,378,726 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	5,274,372 - 5,369,435 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	5,306,227 - 5,393,820 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	4,390,675 - 4,477,877 (-)	NCBI		Celera
RGSC_v3.1	14	5,306,353 - 5,393,463 (-)	NCBI
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

multiple sclerosis (ISO)

TIMES Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (EXP,ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

chloroprene (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenvalerate (EXP)

fluoranthene (ISO)

formaldehyde (ISO)

gentamycin (EXP)

isoprenaline (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methamphetamine (EXP)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

nitrates (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

progesterone (ISO)

pyrethrins (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

temozolomide (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

tungsten (ISO)

tunicamycin (ISO)

valproic acid (EXP,ISO)

vincristine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aspartate transmembrane transport (IBA,IMP)

cellular response to osmotic stress (IMP)

cyclic-GMP-AMP transmembrane import across plasma membrane (IBA,IEA,ISO,ISS)

fat cell differentiation (ISO)

monoatomic anion transmembrane transport (IBA,IEA,ISO,ISS)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

protein hexamerization (IEA,ISO,ISS)

taurine transmembrane transport (IMP)

transmembrane transport (IEA)

Cellular Component

cytoplasm (IBA,IEA,ISO,ISS)

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IEA)

membrane (IEA)

monoatomic ion channel complex (IBA,IEA,IMP,ISO,ISS)

plasma membrane (IBA,IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

volume-sensitive anion channel activity (IEA,IMP,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.	Schober AL, etal., J Physiol. 2017 Nov 15;595(22):6939-6951. doi: 10.1113/JP275053. Epub 2017 Sep 12.

Additional References at PubMed

PMID:12477932	PMID:15184384	PMID:15489334	PMID:19946888	PMID:24790029	PMID:26824658	PMID:29769723

Genomics

Comparative Map Data

Lrrc8c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	4,528,721 - 4,621,259 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	4,531,823 - 4,620,049 (-)	Ensembl				GRCr8
mRatBN7.2	14	4,223,901 - 4,315,590 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	4,227,832 - 4,315,249 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	4,224,741 - 4,312,023 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	5,524,900 - 5,612,184 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	4,230,446 - 4,317,709 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	5,283,655 - 5,378,738 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	5,283,647 - 5,378,726 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	5,274,372 - 5,369,435 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	5,306,227 - 5,393,820 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	4,390,675 - 4,477,877 (-)	NCBI		Celera
RGSC_v3.1	14	5,306,353 - 5,393,463 (-)	NCBI
Cytogenetic Map	14	p22	NCBI

LRRC8C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	89,615,824 - 89,719,533 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	89,632,707 - 89,769,903 (+)	Ensembl			hg38	GRCh38
GRCh37	1	90,098,679 - 90,185,092 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	89,871,350 - 89,953,169 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	88,344,351 - 88,430,780 (+)	NCBI		Celera
Cytogenetic Map	1	p22.2	NCBI
HuRef	1	88,215,951 - 88,302,419 (+)	NCBI		HuRef
CHM1_1	1	90,213,622 - 90,300,056 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	89,459,056 - 89,562,765 (+)	NCBI		T2T-CHM13v2.0

Lrrc8c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	105,666,850 - 105,760,884 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	105,667,254 - 105,760,884 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	105,519,345 - 105,613,018 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	105,519,388 - 105,613,018 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	105,948,490 - 106,037,973 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	105,759,773 - 105,849,256 (+)	NCBI		MGSCv36	mm8
Celera	5	102,631,726 - 102,729,227 (+)	NCBI		Celera
Cytogenetic Map	5	E5	NCBI
cM Map	5	50.68	NCBI

Lrrc8c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	4,460,212 - 4,494,317 (-)	Ensembl
ChiLan1.0	NW_004955423	4,460,212 - 4,494,317 (-)	NCBI	ChiLan1.0	ChiLan1.0

LRRC8C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	137,298,993 - 137,386,330 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	136,454,826 - 136,542,198 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	92,299,691 - 92,384,733 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	91,001,695 - 91,134,865 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	91,105,551 - 91,138,447 (+)	Ensembl			panPan2	panpan1.1

LRRC8C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	58,895,769 - 58,932,729 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	58,899,996 - 58,932,729 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	61,605,421 - 61,690,225 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	59,407,523 - 59,492,055 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	59,409,555 - 59,493,796 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	58,981,235 - 59,065,445 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	58,934,585 - 59,019,172 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	59,414,770 - 59,499,275 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lrrc8c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	99,823,337 - 99,897,484 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	9,049,944 - 9,124,619 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	9,050,495 - 9,124,649 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC8C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	126,957,105 - 127,037,216 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	126,957,099 - 127,079,042 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	138,996,955 - 139,119,829 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC8C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	43,752,341 - 43,842,958 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	43,752,370 - 43,842,766 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	74,090,984 - 74,181,626 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc8c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	8,009,901 - 8,096,652 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624742	8,010,849 - 8,096,567 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Lrrc8c
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	15,242,452 - 15,329,634 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Lrrc8c
1671 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	94
Count of miRNA genes:	70
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000002896
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3957878	21572472	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3957878	24886169	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3957878	18558812	Rat
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
724541	Niddm53	Non-insulin dependent diabetes mellitus QTL 53		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	3957878	9393298	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3957878	31121464	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	11334906	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	17877928	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat

Markers in Region

AI326115

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	4,228,029 - 4,228,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	5,287,784 - 5,287,960	NCBI	Rnor6.0
Rnor_5.0	14	5,278,501 - 5,278,677	UniSTS	Rnor5.0
RGSC_v3.4	14	5,306,420 - 5,306,596	UniSTS	RGSC3.4
Celera	14	4,390,868 - 4,391,044	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH135313

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	4,266,065 - 4,266,285 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	5,325,890 - 5,326,109	NCBI	Rnor6.0
Rnor_5.0	14	5,316,607 - 5,316,826	UniSTS	Rnor5.0
RGSC_v3.4	14	5,344,454 - 5,344,673	UniSTS	RGSC3.4
Celera	14	4,428,886 - 4,429,105	UniSTS
RH 3.4 Map	14	80.7	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH137556

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	4,255,709 - 4,255,833 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	5,315,461 - 5,315,584	NCBI	Rnor6.0
Rnor_5.0	14	5,306,178 - 5,306,301	UniSTS	Rnor5.0
RGSC_v3.4	14	5,334,097 - 5,334,220	UniSTS	RGSC3.4
Celera	14	4,418,530 - 4,418,653	UniSTS
Cytogenetic Map	14	p22	UniSTS

BE096967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	4,268,264 - 4,268,429 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	5,328,088 - 5,328,252	NCBI	Rnor6.0
Rnor_5.0	14	5,318,805 - 5,318,969	UniSTS	Rnor5.0
RGSC_v3.4	14	5,346,652 - 5,346,816	UniSTS	RGSC3.4
Celera	14	4,431,084 - 4,431,248	UniSTS
RH 3.4 Map	14	84.7	UniSTS
Cytogenetic Map	14	p22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC100076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002896 ⟹ ENSRNOP00000002896

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	14	5,283,647 - 5,378,726 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104559 ⟹ ENSRNOP00000082962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	4,532,658 - 4,620,014 (-)	Ensembl
mRatBN7.2 Ensembl	14	4,227,832 - 4,315,249 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000161051 ⟹ ENSRNOP00000105882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	4,531,823 - 4,620,049 (-)	Ensembl

RefSeq Acc Id:

NM_001037179 ⟹ NP_001032256

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	4,532,657 - 4,620,014 (-)	NCBI
mRatBN7.2	14	4,227,837 - 4,315,205 (-)	NCBI
Rnor_6.0	14	5,287,591 - 5,378,698 (-)	NCBI
Rnor_5.0	14	5,274,372 - 5,369,435 (-)	NCBI
RGSC_v3.4	14	5,306,227 - 5,393,820 (-)	RGD
Celera	14	4,390,675 - 4,477,877 (-)	RGD

Sequence:

show sequence

AGCTGGGGCGTTAGCTGCGTCCCGGCTCAGAGCCCGCGAAGAGGACGAGGACCGAGGCGCCGCC
GCGTCCCTGGCCGTAGCACTCTGGTCGCGACAAGCCATGAGCAGCGACGCCGCGGTCGCTGGCC
GTCGCTGAGCCCAACCCGGACACAGCTCGCCGCGCCCTGGCATCCTGTTTTGCGGACACCCTCG
CCCCCAGAGATTAATGTGGCTGCTTATGACTAAGAATTCTGGGACCACAGATGTTCAGAGAAGT
AACATATACATATAAGAAACATGATTCCAGTGACCGAGTTCCGGCAGTTCTCCGAGCAGCAGCC
TGCCTTCCGGGTGCTGAAGCCGTGGTGGGATGTGTTCACGGACTACCTCTCGGTGGCCATGCTG
ATGATCGGGGTGTTTGGATGTACTTTACAAGTCATGCAAGACAAGATCATCTGCCTCCCAAAAA
GAGTGCAGCCTGCTCAGAACCACTCTTCCCTCTCCAACGTCTCCCAGACTGTGATCAATACCAC
CCCGCTGCCCCCACCTAAACCCTCTCCGACCAACCCGGCGACCGTGGAGATGAAGGGACTGAAG
ACAGACCTGGACCTCCAGCAGTACAGTTTCATCAACCAGATGTGCTACGAGCGAGCCCTCCACT
GGTATGCCAAGTACTTCCCGTACCTTGTGCTCATCCACACCCTGGTCTTCATGCTCTGCAGCAA
CTTCTGGTTCAAGTTCCCTGGATCTAGTTCCAAAATAGAACATTTCATCTCCATCCTGGGGAAG
TGCTTCGACTCCCCGTGGACCACTCGGGCTCTCTCCGAGGTGTCTGGCGAGGACTCCGAAGAGA
AGGACAATAGGAAGAACAACATGAACAGGTCCAACACCATCCAGTCCGGTCCGGAAGGCAGCCT
GGTCAAGTCCCAGTCTCTCAAGTCAATTCCCGAGAAGTTCGTGGTTGACAAATCCACTGCGGGG
GCTCTGGACAAGAAGGAAGGTGAACAGGCCAAGGCCTTGTTCGAGAAGGTTAAGAAGTTCAGAC
TGCACGTGGAGGAAGGTGACATCCTGTATGCCATGTATGTGCGGCAGACTGTGCTTAAGGTCAT
CAAGTTCCTGATCATCATCGCCTACAACAGTGCTCTGGTTTCCAAAGTCCAGTTCACCGTGGAC
TGCAATGTGGACATCCAGGACATGACGGGCTATAAGAACTTTTCCTGCAATCACACCATGGCTC
ATTTGTTCTCCAAACTCTCCTTTTGCTACCTGTGCTTTGTAAGCATCTACGGCCTGACGTGCCT
TTATACCTTGTACTGGCTGTTCTACCGTTCTCTGAGGGAGTACTCTTTTGAGTATGTCCGGCAG
GAGACTGGAATCGATGACATTCCGGACGTGAAAAATGACTTTGCCTTTATGCTCCATATGATAG
ACCAGTATGACCCTCTCTATTCCAAGAGGTTTGCGGTGTTCCTCTCTGAGGTCAGCGAGAACAA
GTTAAAGCAGCTCAACTTAAATAACGAGTGGACCCCCGACAAGCTGCGGCAGAAGCTGCAGACG
AATGCCCACAACCGCCTGGAGCTGCCTCTCATCATGCTGTCTGGCCTCCCAGACACCGTGTTCG
AGATCACGGAGTTACAGTCCCTGAAGCTGGAGATCATTAAGAACGTCATGATACCCGCCACCAT
CGCCCAGCTAGACAACCTTCAGGAGCTCTCCCTCCACCAGTGCTCCGTCAAGATCCACAGTGCG
GCACTCTCCTTCCTGAAGGAGAATCTCAAGGTCTTGAGCGTCAAGTTCGATGACATGAGGGAGC
TGCCCCCCTGGATGTACGGCCTCCGGAATCTGGAAGAGCTCTATCTGGTTGGCTCTCTGAGTCA
CGACATCTCCAAAAACGTCACCCTGGAGTCCCTGCGGGACCTCAAAAGCCTTAAAATCCTTTCC
ATCAAGAGCAACGTCTCCAAGATCCCTCAGGCCGTGGTGGATGTGTCCAGCCACCTCCAGAAGA
TGTGCATTCACAACGACGGCACCAAGCTGGTAATGCTCAACAACCTGAAGAAGATGACCAACCT
GACCGAGCTGGAACTGGTCCACTGCGACCTGGAACGCATTCCCCACGCCGTGTTCAGCCTGCTC
AGTCTCCAGGAGCTGGACCTGAAGGAGAACAACCTGAAGTCCATAGAGGAGATCGTGAGTTTCC
AGCACTTGAGAAAGCTAACCGTGCTCAAACTGTGGTATAACAGCATCGCTTACATCCCAGAGCA
CATCAAGAAACTGACCAGCCTGGAGCGACTGTTTTTCAGCCACAATAAGGTAGAAGTGCTTCCC
TCCCACCTCTTCCTGTGCAACAAAATCAGATACCTGGACCTGTCCTATAACGACATTCGCTTCA
TCCCGCCCGAAATCGGGGTTCTGCAAAGTTTACAGTATTTCTCCATCACCTGTAACAAAGTGGA
GAGCCTCCCGGATGAACTCTACTTCTGCAAGAAACTTAAAACATTGAAGATCGGGAAAAACAGC
CTCTCTGTACTTTCACCAAAAATTGGAAACTTACTATTTCTTTCCTACTTAGACATCAAAGGCA
ATCACTTTGAAGTCCTCCCTCCCGAGCTGGGAGACTGCCGGGCTCTGAAACGAGCCGGGCTGGT
TGTGGAAGACGCTCTGTTTGAGACTCTGCCCTCAGATGTCCGGGAGCAAATGAAAGCAGACTAA
CTTATTTTTCATCAAAATATGACTGAAACATGCTTCTACCAAATACAATATAAAGAATTAGGTA
GTCCTAATGCCTTTCCTATATTATTTTTTTTCTTTTCCACACCAAGACATGTACACAAAGATCG
AGTAAGGAGTATGTATTTTTTAATAAAAGTTTAATTGTAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

hide sequence

RefSeq Acc Id:

XM_006250542 ⟹ XP_006250604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	4,528,721 - 4,621,259 (-)	NCBI
mRatBN7.2	14	4,223,901 - 4,315,588 (-)	NCBI
Rnor_6.0	14	5,283,655 - 5,378,738 (-)	NCBI
Rnor_5.0	14	5,274,372 - 5,369,435 (-)	NCBI

Sequence:

show sequence

GCAGGCGGGGAGGCACCGGGGAGGAGGAACAGGGCTGCGGAGCTGGGGCGTTAGCTGCGTCCCG
GCTCAGAGCCCGCGAAGAGGACGAGGACCGAGGCGCCGCCGCGTCCCTGGCCGTAGCACTCTGG
TCGCGACAAGCCATGAGCAGCGACGCCGCGGTCGCTGGCCGTCGCTGAGCCCAACCCGGACACA
GCTCGCCGCGCCCTGGCATCCTGTTTTGCGGACACCCTCGCCCCCAGAGAAACATGATTCCAGT
GACCGAGTTCCGGCAGTTCTCCGAGCAGCAGCCTGCCTTCCGGGTGCTGAAGCCGTGGTGGGAT
GTGTTCACGGACTACCTCTCGGTGGCCATGCTGATGATCGGGGTGTTTGGATGTACTTTACAAG
TCATGCAAGACAAGATCATCTGCCTCCCAAAAAGAGTGCAGCCTGCTCAGAACCACTCTTCCCT
CTCCAACGTCTCCCAGACTGTGATCAATACCACCCCGCTGCCCCCACCTAAACCCTCTCCGACC
AACCCGGCGACCGTGGAGATGAAGGGACTGAAGACAGACCTGGACCTCCAGCAGTACAGTTTCA
TCAACCAGATGTGCTACGAGCGAGCCCTCCACTGGTATGCCAAGTACTTCCCGTACCTTGTGCT
CATCCACACCCTGGTCTTCATGCTCTGCAGCAACTTCTGGTTCAAGTTCCCTGGATCTAGTTCC
AAAATAGAACATTTCATCTCCATCCTGGGGAAGTGCTTCGACTCCCCGTGGACCACTCGGGCTC
TCTCCGAGGTGTCTGGCGAGGACTCCGAAGAGAAGGACAATAGGAAGAACAACATGAACAGGTC
CAACACCATCCAGTCCGGTCCGGAAGGCAGCCTGGTCAAGTCCCAGTCTCTCAAGTCAATTCCC
GAGAAGTTCGTGGTTGACAAATCCACTGCGGGGGCTCTGGACAAGAAGGAAGGTGAACAGGCCA
AGGCCTTGTTCGAGAAGGTTAAGAAGTTCAGACTGCACGTGGAGGAAGGTGACATCCTGTATGC
CATGTATGTGCGGCAGACTGTGCTTAAGGTCATCAAGTTCCTGATCATCATCGCCTACAACAGT
GCTCTGGTTTCCAAAGTCCAGTTCACCGTGGACTGCAATGTGGACATCCAGGACATGACGGGCT
ATAAGAACTTTTCCTGCAATCACACCATGGCTCATTTGTTCTCCAAACTCTCCTTTTGCTACCT
GTGCTTTGTAAGCATCTACGGCCTGACGTGCCTTTATACCTTGTACTGGCTGTTCTACCGTTCT
CTGAGGGAGTACTCTTTTGAGTATGTCCGGCAGGAGACTGGAATCGATGACATTCCGGACGTGA
AAAATGACTTTGCCTTTATGCTCCATATGATAGACCAGTATGACCCTCTCTATTCCAAGAGGTT
TGCGGTGTTCCTCTCTGAGGTCAGCGAGAACAAGTTAAAGCAGCTCAACTTAAATAACGAGTGG
ACCCCCGACAAGCTGCGGCAGAAGCTGCAGACGAATGCCCACAACCGCCTGGAGCTGCCTCTCA
TCATGCTGTCTGGCCTCCCAGACACCGTGTTCGAGATCACGGAGTTACAGTCCCTGAAGCTGGA
GATCATTAAGAACGTCATGATACCCGCCACCATCGCCCAGCTAGACAACCTTCAGGAGCTCTCC
CTCCACCAGTGCTCCGTCAAGATCCACAGTGCGGCACTCTCCTTCCTGAAGGAGAATCTCAAGG
TCTTGAGCGTCAAGTTCGATGACATGAGGGAGCTGCCCCCCTGGATGTACGGCCTCCGGAATCT
GGAAGAGCTCTATCTGGTTGGCTCTCTGAGTCACGACATCTCCAAAAACGTCACCCTGGAGTCC
CTGCGGGACCTCAAAAGCCTTAAAATCCTTTCCATCAAGAGCAACGTCTCCAAGATCCCTCAGG
CCGTGGTGGATGTGTCCAGCCACCTCCAGAAGATGTGCATTCACAACGACGGCACCAAGCTGGT
AATGCTCAACAACCTGAAGAAGATGACCAACCTGACCGAGCTGGAACTGGTCCACTGCGACCTG
GAACGCATTCCCCACGCCGTGTTCAGCCTGCTCAGTCTCCAGGAGCTGGACCTGAAGGAGAACA
ACCTGAAGTCCATAGAGGAGATCGTGAGTTTCCAGCACTTGAGAAAGCTAACCGTGCTCAAACT
GTGGTATAACAGCATCGCTTACATCCCAGAGCACATCAAGAAACTGACCAGCCTGGAGCGACTG
TTTTTCAGCCACAATAAGGTAGAAGTGCTTCCCTCCCACCTCTTCCTGTGCAACAAAATCAGAT
ACCTGGACCTGTCCTATAACGACATTCGCTTCATCCCGCCCGAAATCGGGGTTCTGCAAAGTTT
ACAGTATTTCTCCATCACCTGTAACAAAGTGGAGAGCCTCCCGGATGAACTCTACTTCTGCAAG
AAACTTAAAACATTGAAGATCGGGAAAAACAGCCTCTCTGTACTTTCACCAAAAATTGGAAACT
TACTATTTCTTTCCTACTTAGACATCAAAGGCAATCACTTTGAAGTCCTCCCTCCCGAGCTGGG
AGACTGCCGGGCTCTGAAACGAGCCGGGCTGGTTGTGGAAGACGCTCTGTTTGAGACTCTGCCC
TCAGATGTCCGGGAGCAAATGAAAGCAGACTAACTTATTTTTCATCAAAATATGACTGAAACAT
GCTTCTACCAAATACAATATAAAGAATTAGGTAGTCCTAATGCCTTTCCTATATTATTTTTTTT
CTTTTCCACACCAAGACATGTACACAAAGATCGAGTAAGGAGTATGTATTTTTTAATAAAAGTT
TAATTGTATTTTTTCAATATTAATATTTTAAAGTTTTATTTATCCTGGAAGCTGACTCATCTGT
TACTGCTTTCTGCCAGCAGGGATGGGTAGTTCCAACTGGCCTTGGGTTTTGCTTGAGAGCTTGA
GCTCATTCTTGTAAGAGGAAAGGGATCGTAGGTCGCGTGCATTTTGGCATAGTCTGAATGGGTA
GAGATATTCCGCCAACACCACCCTTAGTTCTTTCTACCCGTCAGAGCCCTTGGCGTGTTTCACC
GTGTGCACTGAGGCGAGGAGTCTATGCCAGCTGTTTTACTGTGAGCCTCCGCCTTCACGGGTCA
GGTGGTGCTACTCTGTAGGAAACCCTAGACTGTGAGCTCACACAAGTGCACTGTCACAGAGTAT
TACCCTGAGAAATCCCCTGCCTCTGACAGCGTTAATTGTATTATTTCCTAAACAGTTTCAGTTA
ACCTCGGCCCGGCTTTGTAAGTGGGTGAAGAAAGGAACCCCCTGTGGTTGCCGTCCTTGCGCGC
ATGCGTGCATTGTTTGCTGTCTAACTGATTCGTGTTTTTACCACCATCCTAAAATATGCCATCA
AAAATTAAATACAACCACCGCCACCCCCATCCGCCTCAGTATTGCCATATGGTACTGTTGAACA
ACCTTGGGGAAATTAGATTTATTTCAATATTCTGGCAGATAATTAAATTTTAAATCATAGAATT
AGAAGCCCTGTTTTGAGTAATTTAATCATTTTTGATGCCTTGATATGTGGATGCCTCCGATGGA
AAACAATCTTGCTACTAAGGCACTCTGTTAGAAAGCTGATGTATTCCGCACAGACCCCATCCCA
TCCCCTCCCCGGACCCTGTGCCGAGATATCAGTTCACTTTCTGCCTGCTGAACAAAACAGCCCA
CTGTATACAGAAGCACAGCCATCAGTTTCCCGCAAGCCTGCCCTCGAGGCCGATGCCAGTGCGG
CAAGCATGGGAACTCCTCGGCTGTCTGCTTAAGGATGCACCTCACTTAGAGCTGACTAACCTCT
CGGTGTTCTCGCTTAGCAATAGTTCCTGCCTAGTGTCGGGTGAAGCTTTTGTGTGGAGACATGA
GTGACACACTCCACCGACTGGCCTAGGGAAAAATTTAACACCGACAGTGGGAAGATGATTTGAC
TTCCAAAACCCTGTTTTGAAGATCGTTTTCTTGGCCCCCATGACCTTGCCTAGACCTGTTTTTT
TGTGACACGTAGACATGGACAAGGCCTGGGAAACACATGGTCCTCCTCGTCTGAGTTAAGACAG
AGAGCTGTGAGGGTGTAGCTCAGTGACGAAGCGCTTGTCCAGCGCTGTGCCCGGAGTCTGAGTT
TAGTGACCTGGGGGACGGGATTCATGGCGGTGGGTGGAGGAAGAGCAGTGAACAATCGTGCGAG
GGGCCAGCCATGTGCAAGCACTTCTGTCTTCTGCTTAAAGTTTCAGTCATGATTTCTTTAAACC
TGGAATTAAGATAATAATATTTTGAAATACTATTATGGCTTATATGTCTTATATGAAGAAATAT
TCAGTTTCAGAATATTAAATCATATGAATCACGTGCCATGTTCAGAAAAGCTCTGTCTTAAAGA
ACTTACGGGCAGATTGTCTGTTATTGAGCATGGGTAGCCTGTTGTGGAAATGTAAATTGAACCA
ATGAATGCACTGTGTTGATTGTTAAGACTTGTGGTTATTTCTAACATCACCCTTCCAAGGGGAC
CTATTAGAGTTAAACACCATAGCTAAACTGAAGTCTTTCTCTGGCATTAACTGAAAATTAACCC
ATAGGGGTTCCTAACTGAAGCAAATCGCCAATAATTCAGTTTTATCAAGCTTCCAAATAATTTG
ATTTGTTTTCATAGTGATTGTTTTTTTGCAGGCTCACTCCCAACCTAGGTTGTAAATATCATTC
AATAAACCAGAATAATCCCAAGACTAAAAGGGAAATGTTCATAGATCTTTCTATTAGATTTTTA
TAAAAAAACTTCCAAAGCCTCACAAACTCTGAAGAGTTTGGATTTTCTGACTCCCGTCCTTTTT
AACACGGTAAGCTTTTGTTCGCGTTCTCGCTTTCAGTTACTGTCCAGCCTTCCAACAGGAAACT
CAGGTACCTGAACTGCTGGCTTCTCTAATGTTCTCTGATCTAACTCAGCACAGAGAGGCTGTCT
GCCTCCTCTCTCTGTGTTTTCCAAGTGCTCTTCCTGAGAAGGATCAGCTCTGTCCAACCTCCGA
CTCACAACAAACTGCTGTATAAATCACAAATGTGCCATCTGTACTCTCAACTCCGGGGCTCGCT
TCAAGCTCAAGGTGGCCACGCTGCACAGTGAGGTTTACTAACAGAGTACAGAACAGCCGTCTGG
TGGTGCTGTGGTTGGAAGGTCCTAATAGAACCCCACCTAAGGGACCAGCAAGATGGCTCTGTGG
GGGAATGGCACTTGCCATCCACCTGAGGTCCTGAGCTTGCTCTCCAGGATCCACACAGTGGAAC
AGAGAACCAACTCCCATAAGTCGTCCTCTGACAGGTGCCACGCCACGAGCCCCTACACAAAACG
TGCACAAACCAATTAATGAAAATTTTACACCCAAGAATGTAACACCTCAGAACAGAATTGTGTT
TTCTTATTATGTGATTTGATCTCGTTTTGAATATCAGAACTCTCGATGGGATAAAATTTGTGAT
GTACATGAGGTCCTTTGCATGGCCCACCCAGTCCTTGCCTGGTGTTACAATGAGCTCCAACCGT
CTCTGTGGCGTCCTAAATAGCAAGCAAGCCTGCCCTTTCAGGCTCTTTGGAAATGTCCCTGCCC
CAAAGATGGTGTTCATTTTAATCATAGGCCCTGCTCTGAAAGGTCTGAAACATGGACTCTTCCT
TGGGTTTCCTCAACAAAAGAAGCCCAGTTGTTTTGTTTTGTTTTGTTTTTCCAGTATGCTGGTT
TCTGGCTTTAGTTTATCTCACTCTCTAATCCAATTTTCACACCAAATACCTGATCAACAGTATT
GGCATTTCATCGATACAAAAAAATCTGTTAGCGCTACTCTTGTGAGTCTTGTTGATGTCATTTC
GGTCTTTCAGAGTGTTAGTGAGGACTACATTAAAGAGTTCACACTGGGGCAGAGTCTCAAGAAC
AGGGCTTCATACCCAAGTGGATAAAAATTGCTACCACTGAGGAGACTTCTGGAAGAGTCTATGG
GATGTTTGCACCTTTTCCATTTAGAGACATAGTAAGAAATCCCAGTCTTACCTAGAGCAGCCGT
GAGTTTTCAGGTTTATCTCTCAGTCTTCAATGATAATTATTATATCAGCCTCCCACCCCCACCC
CCAGCAAGTATCTGCTCCCATTCCCCTTCCCAAAGTCACCCACTAACAAAGATGACATTCTTAG
GATTATCTGAGGGAGAGAGAAGAGAGTCTCTGCCCCCAAGGAATTTATATTTTAATCAGAGAGA
TATAGAACATTGGACAGCTTGACTTACTGACCAGATAGCAGCCACTATGTGTTCAGGGTTTGGT
TTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGAGCCAGGGTCTTGCTTTTTAACCCAGGCT
GACCTTAAACTTGAGAGCCTCTTGCCTTGGCTTCCTGGACACTGGATTACAAGTGTTTACTGCA
CACCTGGCCCGAGTGGTTTCTAGTGCATTCGTTTTTGTGTCTTCATTCCCCTGCGACTCGGCTC
TTTGGGGTTGACGCCCCACGCCTTACGTGCTTGCTCGTGTTCGGTTCGCGTCTGTTTGCTATGT
TCATGTGCATTCAGATGGTCGAGGGCTGGCAAACTTCTTGGACTGCCGAGAGAAAGGACTGATG
GTTGGTTTGTCAGAATACATGTTCATGAAAGGAAACCGTCTTAATGTTACTTCGCTATGTAGTG
TACAGGAACAAAAATAAATAAAGTTGTTTTTGTAACGTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001032256	(Get FASTA)	NCBI Sequence Viewer
	XP_006250604	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00077	(Get FASTA)	NCBI Sequence Viewer
	EDL99473	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000082962
	ENSRNOP00000082962.1
GenBank Protein	Q498T9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001032256 ⟸ NM_001037179

- UniProtKB:

Q498T9 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQPAQN
HSSLSNVSQTVINTTPLPPPKPSPTNPATVEMKGLKTDLDLQQYSFINQMCYERALHWYAKYFP
YLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGEDSEEKDNRKNN
MNRSNTIQSGPEGSLVKSQSLKSIPEKFVVDKSTAGALDKKEGEQAKALFEKVKKFRLHVEEGD
ILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLS
FCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLY
SKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQTNAHNRLELPLIMLSGLPDTVFEITELQS
LKLEIIKNVMIPATIAQLDNLQELSLHQCSVKIHSAALSFLKENLKVLSVKFDDMRELPPWMYG
LRNLEELYLVGSLSHDISKNVTLESLRDLKSLKILSIKSNVSKIPQAVVDVSSHLQKMCIHNDG
TKLVMLNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLT
VLKLWYNSIAYIPEHIKKLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGV
LQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKGNHFEVLP
PELGDCRALKRAGLVVEDALFETLPSDVREQMKAD

hide sequence

RefSeq Acc Id:	XP_006250604 ⟸ XM_006250542
- Peptide Label:	isoform X1
- UniProtKB:	Q498T9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQPAQN HSSLSNVSQTVINTTPLPPPKPSPTNPATVEMKGLKTDLDLQQYSFINQMCYERALHWYAKYFP YLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGEDSEEKDNRKNN MNRSNTIQSGPEGSLVKSQSLKSIPEKFVVDKSTAGALDKKEGEQAKALFEKVKKFRLHVEEGD ILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLS FCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLY SKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQTNAHNRLELPLIMLSGLPDTVFEITELQS LKLEIIKNVMIPATIAQLDNLQELSLHQCSVKIHSAALSFLKENLKVLSVKFDDMRELPPWMYG LRNLEELYLVGSLSHDISKNVTLESLRDLKSLKILSIKSNVSKIPQAVVDVSSHLQKMCIHNDG TKLVMLNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLT VLKLWYNSIAYIPEHIKKLTSLERLFFSHNKVEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGV LQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDIKGNHFEVLP PELGDCRALKRAGLVVEDALFETLPSDVREQMKAD hide sequence

Ensembl Acc Id:

ENSRNOP00000002896 ⟸ ENSRNOT00000002896

Ensembl Acc Id:

ENSRNOP00000082962 ⟸ ENSRNOT00000104559

Ensembl Acc Id:

ENSRNOP00000105882 ⟸ ENSRNOT00000161051

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q498T9-F1-model_v2	AlphaFold	Q498T9	1-803	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699166

Promoter ID:

EPDNEW_R9691

Type:

initiation region

Name:

Lrrc8c_1

Description:

leucine rich repeat containing 8 VRAC subunit C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	5,378,670 - 5,378,730	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306585	AgrOrtholog
BioCyc Gene	G2FUF-16553	BioCyc
Ensembl Genes	ENSRNOG00000002122	Ensembl
	ENSRNOG00000065000	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000104559	ENTREZGENE
	ENSRNOT00000104559.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.80.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7386007	IMAGE-MGC_LOAD
InterPro	Leu-rich_rpt	UniProtKB/Swiss-Prot
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot
	LRR_dom_sf	UniProtKB/Swiss-Prot
	LRR_domain-containing	UniProtKB/Swiss-Prot
	LRRC8_Pannexin-like	UniProtKB/Swiss-Prot
KEGG Report	rno:289443	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112653	IMAGE-MGC_LOAD
NCBI Gene	289443	ENTREZGENE
PANTHER	PTHR48051	UniProtKB/Swiss-Prot
	RAS SUPPRESSOR PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	LRR_1	UniProtKB/Swiss-Prot
	LRR_8	UniProtKB/Swiss-Prot
	Pannexin_like	UniProtKB/Swiss-Prot
PhenoGen	Lrrc8c	PhenoGen
PROSITE	LRR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000002122	RatGTEx
	ENSRNOG00000065000	RatGTEx
SMART	LRR_TYP	UniProtKB/Swiss-Prot
Superfamily-SCOP	L domain-like	UniProtKB/Swiss-Prot
UniProt	A0ABK0L6Z7_RAT	UniProtKB/TrEMBL
	A6K5Q3_RAT	UniProtKB/TrEMBL
	LRC8C_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-08-16	Lrrc8c	leucine rich repeat containing 8 VRAC subunit C	Lrrc8c	leucine rich repeat containing 8 family, member C	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Lrrc8c	leucine rich repeat containing 8 family, member C	RGD1306585	similar to hypothetical protein AD158	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1306585	similar to hypothetical protein AD158	RGD1306585_predicted	similar to hypothetical protein AD158 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306585_predicted	similar to hypothetical protein AD158 (predicted)	LOC289443_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289443_predicted	similar to hypothetical protein AD158 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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