Necap1 (NECAP endocytosis associated 1) - Rat Genome Database

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Pathways
Gene: Necap1 (NECAP endocytosis associated 1) Rattus norvegicus
Analyze
Symbol: Necap1
Name: NECAP endocytosis associated 1
RGD ID: 1306053
Description: Involved in presynaptic endocytosis. Is active in presynapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Orthologous to human NECAP1 (NECAP endocytosis associated 1); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adaptin ear-binding clathrin-associated protein; adaptin ear-binding coat-associated protein 1; LOC312694; MGC114570; NECAP endocytosis-associated protein 1; NECAP-1; RGD1306053; similar to RIKEN cDNA 1200016B17
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,775,890 - 157,790,992 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4157,775,896 - 157,790,984 (+)EnsemblGRCr8
mRatBN7.24156,103,935 - 156,119,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4162,373,641 - 162,388,733 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,156,863 - 158,171,955 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,801,946 - 156,817,038 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,709,712 - 155,724,801 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)Ensemblrn6Rnor6.0
Rnor_5.04222,730,478 - 222,745,567 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44159,354,507 - 159,369,596 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4144,924,247 - 144,939,336 (+)NCBICelera
RGSC_v3.14159,599,461 - 159,614,524 (+)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of the localization and function of NECAP 1 in neurons. Murshid A, etal., J Neurochem. 2006 Sep;98(6):1746-62. doi: 10.1111/j.1471-4159.2006.04066.x. Epub 2006 Jul 31.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The NECAP PHear domain increases clathrin accessory protein binding potential. Ritter B, etal., EMBO J. 2007 Sep 19;26(18):4066-77. Epub 2007 Aug 30.
8. NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. Ritter B, etal., PLoS Biol. 2013 Oct;11(10):e1001670. doi: 10.1371/journal.pbio.1001670. Epub 2013 Oct 1.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14555962   PMID:15057822   PMID:15292237   PMID:16903783   PMID:22871113   PMID:29476059  


Genomics

Comparative Map Data
Necap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,775,890 - 157,790,992 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4157,775,896 - 157,790,984 (+)EnsemblGRCr8
mRatBN7.24156,103,935 - 156,119,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4162,373,641 - 162,388,733 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,156,863 - 158,171,955 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,801,946 - 156,817,038 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,709,712 - 155,724,801 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)Ensemblrn6Rnor6.0
Rnor_5.04222,730,478 - 222,745,567 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44159,354,507 - 159,369,596 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4144,924,247 - 144,939,336 (+)NCBICelera
RGSC_v3.14159,599,461 - 159,614,524 (+)NCBI
Cytogenetic Map4q42NCBI
NECAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,082,274 - 8,097,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,076,939 - 8,097,881 (+)Ensemblhg38GRCh38
GRCh37128,234,870 - 8,250,477 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,989,001 - 8,141,634 (+)NCBIBuild 36Build 36hg18NCBI36
Celera129,811,877 - 9,827,432 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,046,534 - 8,062,074 (+)NCBIHuRef
CHM1_1128,234,026 - 8,249,598 (+)NCBICHM1_1
T2T-CHM13v2.0128,095,874 - 8,111,478 (+)NCBIT2T-CHM13v2.0
Necap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,851,516 - 122,865,902 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,851,433 - 122,865,900 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm386122,874,557 - 122,888,943 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,874,474 - 122,888,941 (+)Ensemblmm10GRCm38
MGSCv376122,824,575 - 122,838,959 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366122,840,176 - 122,854,560 (+)NCBIMGSCv36mm8
Celera6124,676,728 - 124,691,173 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map657.96NCBI
Necap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554136,737,785 - 6,754,162 (+)Ensembl
ChiLan1.0NW_0049554136,737,785 - 6,751,672 (+)NCBIChiLan1.0ChiLan1.0
NECAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21013,635,763 - 13,653,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11213,632,524 - 13,654,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,201,908 - 8,217,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,244,137 - 8,259,247 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,243,785 - 8,282,647 (+)EnsemblpanPan2panpan1.1
NECAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,460,545 - 37,472,512 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,460,607 - 37,507,052 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha279,143,445 - 9,155,412 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02737,814,521 - 37,826,493 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,814,508 - 37,864,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,689,204 - 37,701,156 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,730,473 - 37,742,640 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,630,216 - 8,642,197 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Necap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494599,188,170 - 99,200,553 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936892372,284 - 385,202 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936892372,743 - 385,127 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,122,335 - 63,139,664 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1563,122,280 - 63,135,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NECAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,155,432 - 8,170,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,154,976 - 8,171,025 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666089251,027 - 267,789 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Necap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248605,223,610 - 5,237,451 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248605,224,170 - 5,237,235 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Necap1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1624,214,058 - 24,227,920 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Necap1
146 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:149
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000013272
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4150095743159267220Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
AA998017  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24156,113,085 - 156,113,229 (+)MAPPERmRatBN7.2
Rnor_6.04155,718,820 - 155,718,963NCBIRnor6.0
Rnor_5.04222,739,586 - 222,739,729UniSTSRnor5.0
RGSC_v3.44159,363,615 - 159,363,758UniSTSRGSC3.4
Celera4144,933,355 - 144,933,498UniSTS
RH 3.4 Map41002.9UniSTS
Cytogenetic Map4q42UniSTS
RH141222  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24156,118,668 - 156,118,859 (+)MAPPERmRatBN7.2
Rnor_6.04155,724,402 - 155,724,592NCBIRnor6.0
Rnor_5.04222,745,168 - 222,745,358UniSTSRnor5.0
RGSC_v3.44159,369,197 - 159,369,387UniSTSRGSC3.4
Celera4144,938,937 - 144,939,127UniSTS
RH 3.4 Map41002.1UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013272   ⟹   ENSRNOP00000013272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4157,775,896 - 157,790,983 (+)Ensembl
mRatBN7.2 Ensembl4156,103,988 - 156,119,068 (+)Ensembl
Rnor_6.0 Ensembl4155,709,613 - 155,724,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146409   ⟹   ENSRNOP00000106742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4157,775,903 - 157,790,984 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158912   ⟹   ENSRNOP00000104421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4157,775,910 - 157,790,983 (+)Ensembl
RefSeq Acc Id: NM_001029919   ⟹   NP_001025090
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84157,775,903 - 157,790,992 (+)NCBI
mRatBN7.24156,103,978 - 156,119,068 (+)NCBI
Rnor_6.04155,709,712 - 155,724,801 (+)NCBI
Rnor_5.04222,730,478 - 222,745,567 (+)NCBI
RGSC_v3.44159,354,507 - 159,369,596 (+)RGD
Celera4144,924,247 - 144,939,336 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237305   ⟹   XP_006237367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84157,775,890 - 157,790,911 (+)NCBI
mRatBN7.24156,103,959 - 156,119,068 (+)NCBI
Rnor_6.04155,709,736 - 155,724,801 (+)NCBI
Rnor_5.04222,730,478 - 222,745,567 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001025090 (Get FASTA)   NCBI Sequence Viewer  
  XP_006237367 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97496 (Get FASTA)   NCBI Sequence Viewer  
  EDM01977 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013272
  ENSRNOP00000106742
GenBank Protein P69682 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001025090   ⟸   NM_001029919
- UniProtKB: Q4QR67 (UniProtKB/Swiss-Prot),   P69682 (UniProtKB/Swiss-Prot),   A6ILG2 (UniProtKB/TrEMBL),   A0A8L2Q6N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237367   ⟸   XM_006237305
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6N8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013272   ⟸   ENSRNOT00000013272
Ensembl Acc Id: ENSRNOP00000106742   ⟸   ENSRNOT00000146409
Ensembl Acc Id: ENSRNOP00000104421   ⟸   ENSRNOT00000158912
Protein Domains
NECAP PHear

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P69682-F1-model_v2 AlphaFold P69682 1-277 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693373
Promoter ID:EPDNEW_R3898
Type:multiple initiation site
Name:Necap1_1
Description:NECAP endocytosis associated 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04155,709,719 - 155,709,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306053 AgrOrtholog
BioCyc Gene G2FUF-43139 BioCyc
Ensembl Genes ENSRNOG00000009236 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013272 ENTREZGENE
  ENSRNOT00000146409 ENTREZGENE
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7461823 IMAGE-MGC_LOAD
InterPro NECAP_PHear UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:312694 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114570 IMAGE-MGC_LOAD
NCBI Gene 312694 ENTREZGENE
PANTHER ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 1 UniProtKB/Swiss-Prot
  ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED UniProtKB/Swiss-Prot
Pfam DUF1681 UniProtKB/Swiss-Prot
PhenoGen Necap1 PhenoGen
RatGTEx ENSRNOG00000009236 RatGTEx
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
UniProt A0A8L2Q6N8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LRB2_RAT UniProtKB/TrEMBL
  A6ILG2 ENTREZGENE, UniProtKB/TrEMBL
  NECP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4QR67 ENTREZGENE
UniProt Secondary Q4QR67 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Necap1  NECAP endocytosis associated 1  RGD1306053  similar to RIKEN cDNA 1200016B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1306053  similar to RIKEN cDNA 1200016B17  RGD1306053_predicted  similar to RIKEN cDNA 1200016B17 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306053_predicted  similar to RIKEN cDNA 1200016B17 (predicted)  LOC312694_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC312694_predicted  similar to RIKEN cDNA 1200016B17 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL