Rnf2 (ring finger protein 2) - Rat Genome Database

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Gene: Rnf2 (ring finger protein 2) Rattus norvegicus
Analyze
Symbol: Rnf2
Name: ring finger protein 2
RGD ID: 1305491
Description: Predicted to enable several functions, including RING-like zinc finger domain binding activity; histone H2AK119 ubiquitin ligase activity; and zinc ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in response to retinoic acid and spinal cord development. Predicted to be located in euchromatin; nuclear body; and sex chromatin. Predicted to be part of MLL1 complex and PRC1 complex. Predicted to be active in cytoplasm and nucleus. Biomarker of spina bifida. Human ortholog(s) of this gene implicated in Luo-Schoch-Yamamoto syndrome. Orthologous to human RNF2 (ring finger protein 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RING2; LOC304850; MGC114502; RING finger protein 1B; RING-type E3 ubiquitin transferase RING2; RING1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,103,943 - 66,136,038 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1366,083,653 - 66,133,161 (-)EnsemblGRCr8
mRatBN7.21363,553,964 - 63,584,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1366,173,599 - 66,202,587 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,438,219 - 67,467,208 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,701,587 - 64,730,534 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,829,714 - 68,859,920 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,830,620 - 68,858,809 (-)Ensemblrn6Rnor6.0
Rnor_5.01373,791,946 - 73,821,968 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41366,345,663 - 66,373,826 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1363,485,726 - 63,513,888 (-)NCBICelera
RGSC_v3.11366,359,742 - 66,387,906 (-)NCBI
Cytogenetic Map13q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
cytoplasm  (IEA,ISO,ISS)
euchromatin  (IEA,ISO)
heterochromatin  (IEA,ISO)
MLL1 complex  (IEA,ISO,ISS)
nuclear body  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)
PcG protein complex  (IBA,IEA,ISO,ISS)
PRC1 complex  (IEA,ISO,ISS)
ribonucleoprotein complex  (IEA,ISO)
sex chromatin  (IEA,ISO)
ubiquitin ligase complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
3. The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. Martinez-Romero C, etal., J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
10. Retinal proteomic changes under different ischemic conditions - implication of an epigenetic regulatory mechanism. Stowell C, etal., Int J Physiol Pathophysiol Pharmacol. 2010 Jun 30;2(2):148-160.
11. Polycomb group proteins are essential for spinal cord development. Wang C, etal., Front Biosci (Landmark Ed). 2010 Jun 1;15:1018-22.
Additional References at PubMed
PMID:12167701   PMID:12183370   PMID:12477932   PMID:12589020   PMID:14557078   PMID:15489334   PMID:15525528   PMID:15741318   PMID:15960975   PMID:16359901   PMID:16624538   PMID:16687444  
PMID:16714294   PMID:16943429   PMID:18311137   PMID:18629613   PMID:19636380   PMID:21282530   PMID:22770845   PMID:23027973   PMID:23486062   PMID:24034696   PMID:25519132   PMID:28596365  
PMID:30361391  


Genomics

Comparative Map Data
Rnf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,103,943 - 66,136,038 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1366,083,653 - 66,133,161 (-)EnsemblGRCr8
mRatBN7.21363,553,964 - 63,584,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1366,173,599 - 66,202,587 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,438,219 - 67,467,208 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,701,587 - 64,730,534 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,829,714 - 68,859,920 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,830,620 - 68,858,809 (-)Ensemblrn6Rnor6.0
Rnor_5.01373,791,946 - 73,821,968 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41366,345,663 - 66,373,826 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1363,485,726 - 63,513,888 (-)NCBICelera
RGSC_v3.11366,359,742 - 66,387,906 (-)NCBI
Cytogenetic Map13q21NCBI
RNF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,045,558 - 185,102,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,044,865 - 185,102,603 (+)Ensemblhg38GRCh38
GRCh371185,014,690 - 185,071,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361183,281,174 - 183,338,363 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341181,746,207 - 181,803,397NCBI
Celera1158,125,254 - 158,182,437 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1156,249,794 - 156,306,846 (+)NCBIHuRef
CHM1_11186,434,264 - 186,493,430 (+)NCBICHM1_1
T2T-CHM13v2.01184,402,444 - 184,459,513 (+)NCBIT2T-CHM13v2.0
Rnf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,345,159 - 151,376,562 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,333,755 - 151,376,706 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381151,469,398 - 151,500,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,458,004 - 151,500,955 (-)Ensemblmm10GRCm38
MGSCv371153,316,536 - 153,347,953 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361153,231,624 - 153,263,041 (-)NCBIMGSCv36mm8
Celera1153,898,457 - 153,929,917 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map164.15NCBI
Rnf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540623,672,947 - 23,725,253 (+)Ensembl
ChiLan1.0NW_00495540623,672,947 - 23,725,253 (+)NCBIChiLan1.0ChiLan1.0
RNF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2164,620,643 - 64,679,042 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,304,249 - 64,362,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,568,438 - 160,626,783 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,721,554 - 164,779,420 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,721,458 - 164,779,420 (+)EnsemblpanPan2panpan1.1
RNF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1718,240,672 - 18,283,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl718,236,115 - 18,281,387 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha717,818,956 - 17,868,157 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0717,967,438 - 18,016,584 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl717,967,947 - 18,014,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1717,876,830 - 17,926,016 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0717,984,666 - 18,033,949 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0718,115,806 - 18,164,938 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934487,222,673 - 87,263,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364815,070,578 - 5,110,068 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364815,070,578 - 5,110,087 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9126,172,301 - 126,287,603 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19126,172,637 - 126,284,567 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29138,670,468 - 138,730,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12544,289,662 - 44,345,168 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2544,291,576 - 44,345,236 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605545,500,165 - 45,555,796 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248148,470,818 - 8,516,252 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rnf2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11030,898,434 - 30,926,395 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rnf2
298 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:105
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000065944
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat

Markers in Region
RH129133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,554,895 - 63,555,075 (+)MAPPERmRatBN7.2
Rnor_6.01368,830,646 - 68,830,825NCBIRnor6.0
Rnor_5.01373,792,878 - 73,793,057UniSTSRnor5.0
RGSC_v3.41366,345,690 - 66,345,869UniSTSRGSC3.4
Celera1363,485,753 - 63,485,932UniSTS
RH 3.4 Map13221.4UniSTS
Cytogenetic Map13q21UniSTS
RH143600  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,554,588 - 63,554,872 (+)MAPPERmRatBN7.2
Rnor_6.01368,830,339 - 68,830,622NCBIRnor6.0
Rnor_5.01373,792,571 - 73,792,854UniSTSRnor5.0
RGSC_v3.41366,345,383 - 66,345,666UniSTSRGSC3.4
Celera1363,485,446 - 63,485,729UniSTS
RH 3.4 Map13300.4UniSTS
Cytogenetic Map13q21UniSTS
AW533161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,555,387 - 63,555,562 (+)MAPPERmRatBN7.2
Rnor_6.01368,831,138 - 68,831,312NCBIRnor6.0
Rnor_5.01373,793,370 - 73,793,544UniSTSRnor5.0
RGSC_v3.41366,346,182 - 66,346,356UniSTSRGSC3.4
Celera1363,486,245 - 63,486,419UniSTS
RH 3.4 Map13221.1UniSTS
Cytogenetic Map13q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000065944   ⟹   ENSRNOP00000061975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1366,103,943 - 66,132,911 (-)Ensembl
mRatBN7.2 Ensembl1363,554,870 - 63,583,035 (-)Ensembl
Rnor_6.0 Ensembl1368,830,620 - 68,858,781 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092053   ⟹   ENSRNOP00000068794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1366,083,653 - 66,132,911 (-)Ensembl
mRatBN7.2 Ensembl1363,554,863 - 63,583,054 (-)Ensembl
Rnor_6.0 Ensembl1368,831,371 - 68,858,809 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095575   ⟹   ENSRNOP00000094293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1366,096,600 - 66,132,911 (-)Ensembl
mRatBN7.2 Ensembl1363,554,863 - 63,583,054 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100223   ⟹   ENSRNOP00000097279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1366,103,943 - 66,133,161 (-)Ensembl
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)Ensembl
RefSeq Acc Id: NM_001401380   ⟹   NP_001388309
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81366,103,943 - 66,132,911 (-)NCBI
mRatBN7.21363,553,964 - 63,582,933 (-)NCBI
RefSeq Acc Id: XM_063272315   ⟹   XP_063128385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81366,104,034 - 66,136,038 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001388309 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128385 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98941 (Get FASTA)   NCBI Sequence Viewer  
  BAN09113 (Get FASTA)   NCBI Sequence Viewer  
  EDM09570 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061975.1
  ENSRNOP00000097279
GenBank Protein Q4KLY4 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000068794   ⟸   ENSRNOT00000092053
Ensembl Acc Id: ENSRNOP00000061975   ⟸   ENSRNOT00000065944
Ensembl Acc Id: ENSRNOP00000097279   ⟸   ENSRNOT00000100223
Ensembl Acc Id: ENSRNOP00000094293   ⟸   ENSRNOT00000095575
RefSeq Acc Id: NP_001388309   ⟸   NM_001401380
- UniProtKB: Q4KLY4 (UniProtKB/Swiss-Prot),   M5AJY0 (UniProtKB/TrEMBL),   A0A0G2JTP7 (UniProtKB/TrEMBL),   A6ICS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128385   ⟸   XM_063272315
- Peptide Label: isoform X1
- UniProtKB: Q4KLY4 (UniProtKB/Swiss-Prot),   M5AJY0 (UniProtKB/TrEMBL),   A0A0G2JTP7 (UniProtKB/TrEMBL),   A6ICS7 (UniProtKB/TrEMBL)
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLY4-F1-model_v2 AlphaFold Q4KLY4 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698885
Promoter ID:EPDNEW_R9410
Type:multiple initiation site
Name:Rnf2_1
Description:ring finger protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01368,858,669 - 68,858,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305491 AgrOrtholog
BioCyc Gene G2FUF-17930 BioCyc
Ensembl Genes ENSRNOG00000002454 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065944.3 UniProtKB/Swiss-Prot
  ENSRNOT00000100223 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7456372 IMAGE-MGC_LOAD
InterPro RAWUL UniProtKB/Swiss-Prot
  RING1/RING2 UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
MGC_CLONE MGC:114502 IMAGE-MGC_LOAD
NCBI Gene 304850 ENTREZGENE
PANTHER PTHR46076 UniProtKB/Swiss-Prot
  PTHR46076:SF4 UniProtKB/Swiss-Prot
Pfam RAWUL UniProtKB/Swiss-Prot
  zf-C3HC4_2 UniProtKB/Swiss-Prot
PhenoGen Rnf2 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002454 RatGTEx
SMART RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
UniProt A0A0G2JTP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQI2_RAT UniProtKB/TrEMBL
  A0A8I6GLZ9_RAT UniProtKB/TrEMBL
  A6ICS7 ENTREZGENE, UniProtKB/TrEMBL
  M5AJY0 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLY4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Rnf2  ring finger protein 2  Rnf2_predicted  ring finger protein 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rnf2_predicted  ring finger protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED