Wdr5 (WD repeat domain 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Wdr5 (WD repeat domain 5) Rattus norvegicus
Analyze
Symbol: Wdr5
Name: WD repeat domain 5
RGD ID: 1305159
Description: Predicted to enable histone H3 reader activity; histone H3K4 methyltransferase activity; and histone binding activity. Involved in neuron projection development. Predicted to be located in nucleus. Predicted to be part of histone acetyltransferase complex and histone methyltransferase complex. Orthologous to human WDR5 (WD repeat domain 5); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100912075; LOC108348033; LOC362093; MGC114572; WD repeat-containing protein 5; WD repeat-containing protein 5-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8331,233,048 - 31,254,730 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl331,235,222 - 31,254,727 (+)EnsemblGRCr8
mRatBN7.2310,836,964 - 10,856,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx313,905,180 - 13,924,115 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0322,490,606 - 22,509,541 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,745,229 - 20,764,191 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.036,061,892 - 6,080,724 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)Ensemblrn6Rnor6.0
Rnor_5.0311,422,748 - 11,441,574 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.436,432,879 - 6,451,846 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera35,632,259 - 5,651,225 (+)NCBICelera
RGSC_v3.136,432,099 - 6,450,947 (+)NCBI
Cytogenetic Map3p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Brown SA, etal., Science. 2005 Apr 29;308(5722):693-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression. Nakagawa T and Xiong Y, Mol Cell. 2011 Aug 5;43(3):381-91. doi: 10.1016/j.molcel.2011.05.033.
5. Readout of epigenetic modifications. Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
8. ATAC-king the complexity of SAGA during evolution. Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
9. The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.
Additional References at PubMed
PMID:11551928   PMID:12477932   PMID:15489334   PMID:15960975   PMID:16600877   PMID:17355966   PMID:17500065   PMID:17998332   PMID:18838386   PMID:18838538   PMID:18840606   PMID:19103755  
PMID:19556245   PMID:20018852   PMID:20508642   PMID:22514746   PMID:24051374   PMID:26324722  


Genomics

Comparative Map Data
Wdr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8331,233,048 - 31,254,730 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl331,235,222 - 31,254,727 (+)EnsemblGRCr8
mRatBN7.2310,836,964 - 10,856,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx313,905,180 - 13,924,115 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0322,490,606 - 22,509,541 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,745,229 - 20,764,191 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.036,061,892 - 6,080,724 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)Ensemblrn6Rnor6.0
Rnor_5.0311,422,748 - 11,441,574 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.436,432,879 - 6,451,846 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera35,632,259 - 5,651,225 (+)NCBICelera
RGSC_v3.136,432,099 - 6,450,947 (+)NCBI
Cytogenetic Map3p12NCBI
WDR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,135,199 - 134,159,968 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9134,134,346 - 134,159,971 (+)Ensemblhg38GRCh38
GRCh379137,000,321 - 137,025,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,991,031 - 136,014,915 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349134,034,467 - 134,053,330NCBI
Celera9107,546,368 - 107,570,384 (+)NCBICelera
Cytogenetic Map9q34.2NCBI
HuRef9106,494,213 - 106,518,092 (+)NCBIHuRef
CHM1_19137,147,954 - 137,171,840 (+)NCBICHM1_1
T2T-CHM13v2.09146,348,934 - 146,373,713 (+)NCBIT2T-CHM13v2.0
Wdr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,405,159 - 27,426,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl227,405,169 - 27,426,547 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38227,515,147 - 27,536,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,515,157 - 27,536,535 (+)Ensemblmm10GRCm38
MGSCv37227,370,667 - 27,392,055 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36227,337,223 - 27,358,544 (+)NCBIMGSCv36mm8
Celera227,217,888 - 27,239,293 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Wdr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555133,198,980 - 3,216,468 (+)Ensembl
ChiLan1.0NW_0049555133,198,655 - 3,213,754 (+)NCBIChiLan1.0ChiLan1.0
WDR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2115,211,185 - 5,235,964 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan195,213,518 - 5,238,324 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09105,241,415 - 105,265,925 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19133,848,185 - 133,872,889 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9133,848,185 - 133,872,889 (+)EnsemblpanPan2panpan1.1
WDR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,352,600 - 50,371,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,352,472 - 50,371,236 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha949,631,684 - 49,651,782 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0951,225,059 - 51,245,284 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl951,225,396 - 51,245,435 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1949,985,941 - 50,006,039 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0950,328,703 - 50,348,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0950,406,626 - 50,426,733 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947200,415,266 - 200,430,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366692,943,656 - 2,958,409 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366692,943,759 - 2,959,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1273,560,283 - 273,578,063 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11273,560,274 - 273,577,827 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21307,533,235 - 307,550,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1123,982,998 - 4,007,605 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl123,983,013 - 4,007,119 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660581,089,087 - 1,113,046 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247602,274,813 - 2,292,379 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247602,275,660 - 2,291,796 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Wdr5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v159,130,397 - 9,145,872 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wdr5
141 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:142
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000011556
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
RH141408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2310,856,268 - 10,856,455 (+)MAPPERmRatBN7.2
Rnor_6.036,080,311 - 6,080,497NCBIRnor6.0
Rnor_5.0311,441,161 - 11,441,347UniSTSRnor5.0
RGSC_v3.436,451,451 - 6,451,637UniSTSRGSC3.4
Celera35,650,830 - 5,651,016UniSTS
RH 3.4 Map310.7UniSTS
Cytogenetic Map3p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011556   ⟹   ENSRNOP00000011556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl331,235,222 - 31,254,727 (+)Ensembl
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)Ensembl
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155902   ⟹   ENSRNOP00000101559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl331,235,222 - 31,254,727 (+)Ensembl
RefSeq Acc Id: NM_001039034   ⟹   NP_001034123
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,235,746 - 31,254,712 (+)NCBI
mRatBN7.2310,837,696 - 10,856,664 (+)NCBI
Rnor_6.036,062,593 - 6,080,706 (+)NCBI
Rnor_5.0311,422,748 - 11,441,574 (+)NCBI
RGSC_v3.436,432,879 - 6,451,846 (+)RGD
Celera35,632,259 - 5,651,225 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233831   ⟹   XP_006233893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,235,025 - 31,254,730 (+)NCBI
mRatBN7.2310,836,964 - 10,856,682 (+)NCBI
Rnor_6.036,061,892 - 6,080,724 (+)NCBI
Rnor_5.0311,422,748 - 11,441,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063284063   ⟹   XP_063140133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,233,048 - 31,254,730 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001034123 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233893 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140133 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00157 (Get FASTA)   NCBI Sequence Viewer  
  EDL93432 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011556
GenBank Protein Q498M4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001034123   ⟸   NM_001039034
- UniProtKB: Q498M4 (UniProtKB/Swiss-Prot),   A6JTL5 (UniProtKB/TrEMBL),   A0A8L2Q668 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233893   ⟸   XM_006233831
- Peptide Label: isoform X1
- UniProtKB: Q498M4 (UniProtKB/Swiss-Prot),   A6JTL5 (UniProtKB/TrEMBL),   A0A8L2Q668 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011556   ⟸   ENSRNOT00000011556
RefSeq Acc Id: XP_063140133   ⟸   XM_063284063
- Peptide Label: isoform X1
- UniProtKB: Q498M4 (UniProtKB/Swiss-Prot),   A0A8L2Q668 (UniProtKB/TrEMBL),   A6JTL5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101559   ⟸   ENSRNOT00000155902

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q498M4-F1-model_v2 AlphaFold Q498M4 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691929
Promoter ID:EPDNEW_R2452
Type:initiation region
Name:Wdr5_1
Description:WD repeat domain 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.036,061,938 - 6,061,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305159 AgrOrtholog
BioCyc Gene G2FUF-50294 BioCyc
Ensembl Genes ENSRNOG00000008212 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011556 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7462311 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:362093 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114572 IMAGE-MGC_LOAD
NCBI Gene 362093 ENTREZGENE
PANTHER WD REPEAT-CONTAINING PROTEIN 5 UniProtKB/Swiss-Prot
  WD40 REPEAT PROTEIN UniProtKB/Swiss-Prot
Pfam Beta-prop_WDR5 UniProtKB/Swiss-Prot
PhenoGen Wdr5 PhenoGen
PIRSF GN-bd_beta UniProtKB/Swiss-Prot
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008212 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8L2Q668 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L0I6_RAT UniProtKB/TrEMBL
  A6JTL5 ENTREZGENE, UniProtKB/TrEMBL
  Q498M4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Wdr5  WD repeat domain 5  LOC108348033  WD repeat-containing protein 5-like  Data merged from RGD:11372168 737654 PROVISIONAL
2016-08-02 LOC108348033  WD repeat-containing protein 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-07-29 Wdr5  WD repeat domain 5  LOC100912075  WD repeat-containing protein 5-like  Data merged from RGD:6488995 737654 PROVISIONAL
2012-07-05 LOC100912075  WD repeat-containing protein 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Wdr5  WD repeat domain 5  Wdr5_predicted  WD repeat domain 5 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdr5_predicted  WD repeat domain 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED