Pold2 (DNA polymerase delta 2, accessory subunit) - Rat Genome Database

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Gene: Pold2 (DNA polymerase delta 2, accessory subunit) Rattus norvegicus
Analyze
Symbol: Pold2
Name: DNA polymerase delta 2, accessory subunit
RGD ID: 1304954
Description: Predicted to enable DNA binding activity. Involved in DNA-templated DNA replication. Part of delta DNA polymerase complex. Orthologous to human POLD2 (DNA polymerase delta 2, accessory subunit); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DAN polymerase delta 2, accessory subunit; DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; DNA-directed DNA polymerase delta 2; LOC289758; polymerase (DNA directed), delta 2, accessory subunit; polymerase (DNA directed), delta 2, regulatory subunit; polymerase (DNA) delta 2, accessory subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,962,933 - 84,969,148 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,962,022 - 84,967,874 (-)EnsemblGRCr8
mRatBN7.21480,748,971 - 80,755,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,748,974 - 80,755,160 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,151,054 - 85,157,217 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,391,142 - 86,397,305 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,840,464 - 82,846,627 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,111,416 - 86,117,578 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,111,294 - 86,117,578 (-)Ensemblrn6Rnor6.0
Rnor_5.01486,802,860 - 86,809,022 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,535,757 - 86,541,920 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,633,799 - 79,639,962 (-)NCBICelera
RGSC_v3.11486,554,903 - 86,561,065 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-quinic acid  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol AF  (ISO)
carbon nanotube  (ISO)
cobalt dichloride  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
Cuprizon  (EXP)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
Enterolactone  (ISO)
fenthion  (ISO)
furan  (EXP)
guanine  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
miconazole  (ISO)
mifepristone  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
delta DNA polymerase complex  (IBA,IC,IDA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)
zeta DNA polymerase complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. DNA polymerases and repair synthesis in NER in human cells. Lehmann AR DNA Repair (Amst). 2011 Jul 15;10(7):730-3. doi: 10.1016/j.dnarep.2011.04.023. Epub 2011 May 20.
4. Mechanisms and functions of DNA mismatch repair. Li GM Cell Res. 2008 Jan;18(1):85-98.
5. Calmodulin is involved in the induction of DNA polymerases alpha and delta activities in normal rat kidney cells activated to proliferate. Lopez-Girona A, etal., Biochem Biophys Res Commun. 1995 Dec 14;217(2):566-74.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. A mutation detected in DNA polymerase delta cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme. Popanda O, etal., J Cancer Res Clin Oncol 1999 Nov;125(11):598-608.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11595739   PMID:15489334   PMID:15982757   PMID:22465957  


Genomics

Comparative Map Data
Pold2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,962,933 - 84,969,148 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,962,022 - 84,967,874 (-)EnsemblGRCr8
mRatBN7.21480,748,971 - 80,755,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,748,974 - 80,755,160 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,151,054 - 85,157,217 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,391,142 - 86,397,305 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,840,464 - 82,846,627 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,111,416 - 86,117,578 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,111,294 - 86,117,578 (-)Ensemblrn6Rnor6.0
Rnor_5.01486,802,860 - 86,809,022 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,535,757 - 86,541,920 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,633,799 - 79,639,962 (-)NCBICelera
RGSC_v3.11486,554,903 - 86,561,065 (-)NCBI
Cytogenetic Map14q21NCBI
POLD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,114,680 - 44,124,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,114,631 - 44,124,407 (-)Ensemblhg38GRCh38
GRCh37744,154,279 - 44,163,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,120,812 - 44,129,655 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34743,927,526 - 43,936,370NCBI
Celera744,252,240 - 44,261,103 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,039,545 - 44,048,437 (-)NCBIHuRef
CHM1_1744,158,128 - 44,167,020 (-)NCBICHM1_1
T2T-CHM13v2.0744,273,211 - 44,282,858 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,193,774 - 44,202,666 (-)NCBI
Pold2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,822,180 - 5,828,256 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,822,180 - 5,828,292 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38115,872,180 - 5,878,256 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,872,180 - 5,878,292 (-)Ensemblmm10GRCm38
MGSCv37115,772,183 - 5,778,259 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36115,772,191 - 5,778,220 (-)NCBIMGSCv36mm8
Celera116,363,816 - 6,369,891 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.88NCBI
Pold2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,853,476 - 7,860,108 (+)Ensembl
ChiLan1.0NW_0049554567,853,476 - 7,860,108 (+)NCBIChiLan1.0ChiLan1.0
POLD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,026,199 - 49,035,160 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,350,939 - 97,359,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,829,040 - 44,837,928 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,896,320 - 44,906,084 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,896,320 - 44,905,393 (-)EnsemblpanPan2panpan1.1
POLD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,054,909 - 2,062,351 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,799,626 - 14,807,063 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,799,229 - 14,807,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,430,844 - 14,438,274 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,411,321 - 14,418,752 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pold2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,863,137 - 99,872,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,072,810 - 19,083,669 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,074,871 - 19,083,624 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1851,038,358 - 51,046,779 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11851,038,272 - 51,046,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,932,004 - 55,940,477 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POLD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,544,083 - 14,553,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,545,986 - 14,553,217 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660627,961,746 - 7,970,661 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pold2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,901,075 - 7,908,014 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,901,029 - 7,907,746 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pold2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11174,829,498 - 74,834,492 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pold2
68 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:83
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000019288
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
RH130406  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,962,637 - 84,962,822 (+)Marker Load Pipeline
mRatBN7.21480,748,674 - 80,748,860 (+)MAPPERmRatBN7.2
Rnor_6.01486,111,120 - 86,111,305NCBIRnor6.0
Rnor_5.01486,802,564 - 86,802,749UniSTSRnor5.0
RGSC_v3.41486,535,461 - 86,535,646UniSTSRGSC3.4
Celera1479,633,503 - 79,633,688UniSTS
RH 3.4 Map14573.4UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000019288   ⟹   ENSRNOP00000019288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,962,935 - 84,967,874 (-)Ensembl
mRatBN7.2 Ensembl1480,748,974 - 80,755,160 (-)Ensembl
Rnor_6.0 Ensembl1486,111,418 - 86,117,578 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084633   ⟹   ENSRNOP00000072093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,962,933 - 84,967,874 (-)Ensembl
mRatBN7.2 Ensembl1480,748,974 - 80,755,160 (-)Ensembl
Rnor_6.0 Ensembl1486,111,294 - 86,116,363 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000151876   ⟹   ENSRNOP00000105162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,962,022 - 84,967,874 (-)Ensembl
RefSeq Acc Id: NM_001013050   ⟹   NP_001013068
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,962,933 - 84,969,096 (-)NCBI
mRatBN7.21480,748,971 - 80,755,134 (-)NCBI
Rnor_6.01486,111,416 - 86,117,578 (-)NCBI
Rnor_5.01486,802,860 - 86,809,022 (-)NCBI
RGSC_v3.41486,535,757 - 86,541,920 (-)RGD
Celera1479,633,799 - 79,639,962 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272950   ⟹   XP_063129020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,962,933 - 84,969,037 (-)NCBI
RefSeq Acc Id: XM_063272951   ⟹   XP_063129021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,962,933 - 84,969,148 (-)NCBI
RefSeq Acc Id: XM_063272952   ⟹   XP_063129022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,962,933 - 84,969,085 (-)NCBI
RefSeq Acc Id: NP_001013068   ⟸   NM_001013050
- UniProtKB: Q6AXY4 (UniProtKB/Swiss-Prot),   A6IKQ3 (UniProtKB/TrEMBL),   A0A8L2QAQ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072093   ⟸   ENSRNOT00000084633
Ensembl Acc Id: ENSRNOP00000019288   ⟸   ENSRNOT00000019288
RefSeq Acc Id: XP_063129021   ⟸   XM_063272951
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R542 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129022   ⟸   XM_063272952
- Peptide Label: isoform X2
- UniProtKB: Q6AXY4 (UniProtKB/Swiss-Prot),   A0A8L2QAQ7 (UniProtKB/TrEMBL),   A6IKQ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129020   ⟸   XM_063272950
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R542 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105162   ⟸   ENSRNOT00000151876
Protein Domains
DNA polymerase alpha/delta/epsilon subunit B   DNA polymerase delta subunit OB-fold

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXY4-F1-model_v2 AlphaFold Q6AXY4 1-469 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699465
Promoter ID:EPDNEW_R9989
Type:multiple initiation site
Name:Pold2_1
Description:DNA polymerase delta 2, accessory subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,117,597 - 86,117,657EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304954 AgrOrtholog
BioCyc Gene G2FUF-15117 BioCyc
Ensembl Genes ENSRNOG00000014098 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000084633 ENTREZGENE
Gene3D-CATH 3.60.21.50 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133662 IMAGE-MGC_LOAD
InterPro DNA_pol_a/d/e_bsu UniProtKB/Swiss-Prot
  DNA_pol_D_N UniProtKB/Swiss-Prot
  DNA_pol_delta/II_ssu UniProtKB/Swiss-Prot
  PolD2_C UniProtKB/Swiss-Prot
KEGG Report rno:289758 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94378 IMAGE-MGC_LOAD
NCBI Gene 289758 ENTREZGENE
PANTHER DNA POLYMERASE DELTA SUBUNIT 2 UniProtKB/Swiss-Prot
  PTHR10416 UniProtKB/Swiss-Prot
Pfam DNA_pol_D_N UniProtKB/Swiss-Prot
  DNA_pol_E_B UniProtKB/Swiss-Prot
PhenoGen Pold2 PhenoGen
RatGTEx ENSRNOG00000014098 RatGTEx
UniProt A0A8L2QAQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R542 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LSV0_RAT UniProtKB/TrEMBL
  A6IKQ2_RAT UniProtKB/TrEMBL
  A6IKQ3 ENTREZGENE, UniProtKB/TrEMBL
  A6IKQ4_RAT UniProtKB/TrEMBL
  A6IKQ5_RAT UniProtKB/TrEMBL
  A6IKQ6_RAT UniProtKB/TrEMBL
  DPOD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-29 Pold2  DNA polymerase delta 2, accessory subunit  Pold2  DAN polymerase delta 2, accessory subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-07-21 Pold2  DAN polymerase delta 2, accessory subunit  Pold2  polymerase (DNA) delta 2, accessory subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-09 Pold2  polymerase (DNA) delta 2, accessory subunit  Pold2  polymerase (DNA directed), delta 2, accessory subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-02-27 Pold2  polymerase (DNA directed), delta 2, accessory subunit  Pold2  polymerase (DNA directed), delta 2, regulatory subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pold2  polymerase (DNA directed), delta 2, regulatory subunit  Pold2_predicted  polymerase (DNA directed), delta 2, regulatory subunit (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pold2_predicted  polymerase (DNA directed), delta 2, regulatory subunit (predicted)      Symbol and Name status set to approved 70820 APPROVED