Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Apold1 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of APOLD1 mRNA | CTD | PMID:32145629 | Apold1 | Rat | 17beta-estradiol | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Estradiol results in increased expression of APOLD1 mRNA | CTD | PMID:39298647 | Apold1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of APOLD1 mRNA | CTD | PMID:19933214 | Apold1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of APOLD1 mRNA | CTD | PMID:34747641 | Apold1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APOLD1 mRNA | CTD | PMID:32109520 | Apold1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Apold1 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of APOLD1 mRNA | CTD | PMID:38648751 | Apold1 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of APOLD1 mRNA | CTD | PMID:20188158 | Apold1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of APOLD1 mRNA | CTD | PMID:30951980 | Apold1 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | APOLD1 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of APOLD1 gene | CTD | PMID:31601247 | Apold1 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of APOLD1 mRNA | CTD | PMID:28973697 | Apold1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of APOLD1 mRNA | CTD | PMID:30047161 | Apold1 | Rat | acrolein | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Apold1 | Rat | acrolein | increases expression | EXP | | 6480464 | Acrolein results in increased expression of APOLD1 mRNA | CTD | PMID:38090360 | Apold1 | Rat | acrylamide | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Acrylamide results in increased expression of APOLD1 mRNA | CTD | PMID:35032568 | Apold1 | Rat | acrylamide | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of APOLD1 mRNA | CTD | PMID:32763439 | Apold1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of APOLD1 mRNA | CTD | PMID:33354967 | Apold1 | Rat | aldehydo-D-glucose | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Glucose results in increased expression of APOLD1 mRNA | CTD | PMID:39922521 | Apold1 | Rat | all-trans-retinoic acid | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of APOLD1 mRNA | CTD | PMID:21934132 | Apold1 | Rat | alpha-pinene | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Apold1 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of APOLD1 mRNA | CTD | PMID:30047161 | Apold1 | Rat | aristolochic acid A | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of APOLD1 mRNA | CTD | PMID:33212167 | Apold1 | Rat | arsane | affects methylation | ISO | APOLD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOLD1 gene | CTD | PMID:25304211 | Apold1 | Rat | arsenic atom | affects methylation | ISO | APOLD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOLD1 gene | CTD | PMID:25304211 | Apold1 | Rat | benzo[a]pyrene | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of APOLD1 mRNA | CTD | PMID:32417428 | Apold1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of APOLD1 mRNA | CTD | PMID:25181051 | Apold1 | Rat | bisphenol A | decreases methylation | ISO | APOLD1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of APOLD1 gene | CTD | PMID:31601247 | Apold1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of APOLD1 mRNA | CTD | PMID:34947998|PMID:38750585 | Apold1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of APOLD1 mRNA | CTD | PMID:32145629 | Apold1 | Rat | bisphenol A | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of APOLD1 mRNA | CTD | PMID:30951980|PMID:32156529 | Apold1 | Rat | bisphenol A | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of APOLD1 mRNA | CTD | PMID:25594700 | Apold1 | Rat | bisphenol F | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of APOLD1 mRNA | CTD | PMID:30951980 | Apold1 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of APOLD1 mRNA | CTD | PMID:32479839 | Apold1 | Rat | butanal | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of APOLD1 mRNA | CTD | PMID:26079696 | Apold1 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of APOLD1 mRNA | CTD | PMID:19167457 | Apold1 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of APOLD1 promoter | CTD | PMID:22457795 | Apold1 | Rat | cadmium dichloride | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of APOLD1 mRNA | CTD | PMID:38382870 | Apold1 | Rat | carbon nanotube | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of APOLD1 mRNA | CTD | PMID:25554681 | Apold1 | Rat | carbon nanotube | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of APOLD1 mRNA | CTD | PMID:25554681 | Apold1 | Rat | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of APOLD1 mRNA | CTD | PMID:18500788 | Apold1 | Rat | CGP 52608 | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to APOLD1 gene] | CTD | PMID:28238834 | Apold1 | Rat | chloroprene | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of APOLD1 mRNA | CTD | PMID:23125180 | Apold1 | Rat | chlorpyrifos | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of APOLD1 mRNA | CTD | PMID:37019170 | Apold1 | Rat | cisplatin | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of APOLD1 mRNA | CTD | PMID:27392435 | Apold1 | Rat | cisplatin | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of APOLD1 mRNA | CTD | PMID:27392435 | Apold1 | Rat | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of APOLD1 mRNA | CTD | PMID:20187946 | Apold1 | Rat | D-glucose | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Glucose results in increased expression of APOLD1 mRNA | CTD | PMID:39922521 | Apold1 | Rat | dioxygen | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of APOLD1 mRNA | CTD | PMID:20880076 | Apold1 | Rat | dioxygen | multiple interactions | ISO | Apold1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of APOLD1 mRNA | CTD | PMID:30529165 | Apold1 | Rat | dorsomorphin | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Apold1 | Rat | entinostat | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Apold1 | Rat | entinostat | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of APOLD1 mRNA | CTD | PMID:26272509 | Apold1 | Rat | epoxiconazole | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of APOLD1 mRNA | CTD | PMID:35436446 | Apold1 | Rat | ethyl methanesulfonate | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of APOLD1 mRNA | CTD | PMID:23649840 | Apold1 | Rat | folic acid | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of APOLD1 mRNA | CTD | PMID:25629700 | Apold1 | Rat | formaldehyde | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of APOLD1 mRNA | CTD | PMID:23649840 | Apold1 | Rat | glucose | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Glucose results in increased expression of APOLD1 mRNA | CTD | PMID:39922521 | Apold1 | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of APOLD1 mRNA | CTD | PMID:24915197 | Apold1 | Rat | hydrogen sulfide | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Hydrogen Sulfide results in increased expression of APOLD1 mRNA | CTD | PMID:31843631 | Apold1 | Rat | leflunomide | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of APOLD1 mRNA | CTD | PMID:28988120 | Apold1 | Rat | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of APOLD1 mRNA | CTD | PMID:35283115 | Apold1 | Rat | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of APOLD1 mRNA | CTD | PMID:28801915 | Apold1 | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA | CTD | PMID:19564919 | Apold1 | Rat | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of APOLD1 mRNA | CTD | PMID:19564919 | Apold1 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of APOLD1 mRNA | CTD | PMID:30047161 | Apold1 | Rat | methylisothiazolinone | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in decreased expression of APOLD1 mRNA | CTD | PMID:31629900 | Apold1 | Rat | methylmercury chloride | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of APOLD1 mRNA | CTD | PMID:28001369 | Apold1 | Rat | oxybenzone | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | oxybenzone results in decreased expression of APOLD1 mRNA | CTD | PMID:39343157 | Apold1 | Rat | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of APOLD1 mRNA | CTD | PMID:28623178 | Apold1 | Rat | ozone | multiple interactions | ISO | Apold1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Apold1 | Rat | ozone | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Apold1 | Rat | paracetamol | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of APOLD1 mRNA | CTD | PMID:21420995 | Apold1 | Rat | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of APOLD1 mRNA | CTD | PMID:33387578 | Apold1 | Rat | phenformin | decreases expression | EXP | | 6480464 | Phenformin results in decreased expression of APOLD1 mRNA | CTD | PMID:31324951 | Apold1 | Rat | phenylmercury acetate | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of APOLD1 mRNA | CTD | PMID:26272509 | Apold1 | Rat | phenylmercury acetate | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Apold1 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of APOLD1 mRNA | CTD | PMID:30047161 | Apold1 | Rat | propanal | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of APOLD1 mRNA | CTD | PMID:26079696 | Apold1 | Rat | quercetin | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of APOLD1 mRNA | CTD | PMID:21632981 | Apold1 | Rat | rotenone | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | Rotenone results in increased expression of APOLD1 mRNA | CTD | PMID:32937126 | Apold1 | Rat | SB 431542 | multiple interactions | ISO | APOLD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Apold1 | Rat | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA | CTD | PMID:19564919 | Apold1 | Rat | silicon dioxide | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of APOLD1 mRNA | CTD | PMID:25351596 | Apold1 | Rat | silicon dioxide | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of APOLD1 mRNA | CTD | PMID:29341224 | Apold1 | Rat | silver atom | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Silver results in decreased expression of APOLD1 mRNA | CTD | PMID:27131904 | Apold1 | Rat | silver(0) | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | Silver results in decreased expression of APOLD1 mRNA | CTD | PMID:27131904 | Apold1 | Rat | sodium arsenate | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of APOLD1 mRNA | CTD | PMID:21795629 | Apold1 | Rat | sodium arsenite | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of APOLD1 mRNA | CTD | PMID:29301061 | Apold1 | Rat | sodium arsenite | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of APOLD1 mRNA | CTD | PMID:36209798 | Apold1 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of APOLD1 mRNA | CTD | PMID:30047161 | Apold1 | Rat | temozolomide | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of APOLD1 mRNA | CTD | PMID:31758290 | Apold1 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of APOLD1 mRNA | CTD | PMID:15336504 | Apold1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of APOLD1 mRNA | CTD | PMID:34492290 | Apold1 | Rat | titanium dioxide | decreases expression | ISO | Apold1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of APOLD1 mRNA | CTD | PMID:29264374 | Apold1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of APOLD1 mRNA | CTD | PMID:33387578 | Apold1 | Rat | triclosan | decreases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of APOLD1 mRNA | CTD | PMID:30510588 | Apold1 | Rat | triclosan | increases methylation | ISO | APOLD1 (Homo sapiens) | 6480464 | Triclosan results in increased methylation of APOLD1 gene | CTD | PMID:34523531 | Apold1 | Rat | triphenyl phosphate | affects expression | ISO | APOLD1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of APOLD1 mRNA | CTD | PMID:37042841 | Apold1 | Rat | triptonide | increases expression | ISO | Apold1 (Mus musculus) | 6480464 | triptonide results in increased expression of APOLD1 mRNA | CTD | PMID:33045310 | Apold1 | Rat | valproic acid | affects expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of APOLD1 mRNA | CTD | PMID:25979313 | Apold1 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of APOLD1 mRNA | CTD | PMID:35594946 | Apold1 | Rat | valproic acid | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of APOLD1 mRNA | CTD | PMID:23179753|PMID:27188386|PMID:28001369 | Apold1 | Rat | vincristine | increases expression | ISO | APOLD1 (Homo sapiens) | 6480464 | Vincristine results in increased expression of APOLD1 mRNA | CTD | PMID:23649840 | |






















