Necap2 (NECAP endocytosis associated 2) - Rat Genome Database

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Gene: Necap2 (NECAP endocytosis associated 2) Rattus norvegicus
Analyze
Symbol: Necap2
Name: NECAP endocytosis associated 2
RGD ID: 735063
Description: Predicted to be involved in endocytosis. Predicted to be located in clathrin-coated pit. Predicted to be part of clathrin vesicle coat. Orthologous to human NECAP2 (NECAP endocytosis associated 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adaptin ear-binding coat-associated protein 2; adaptin-ear-binding coat-associated protein 2; MGC72598; NECAP-2; Unknown (protein for MGC:72598)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,653,347 - 158,665,761 (-)NCBIGRCr8
mRatBN7.25153,370,338 - 153,382,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,370,338 - 153,382,729 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,058,617 - 156,070,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,831,889 - 157,844,250 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,821,074 - 157,833,435 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,589,856 - 159,602,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,589,881 - 159,602,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,302,181 - 163,314,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,924,712 - 159,937,073 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,934,907 - 159,947,261 (-)NCBI
Celera5151,734,989 - 151,747,350 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif. Ritter B, etal., EMBO Rep 2003 Nov;4(11):1089-95. Epub 2003 Oct 10.
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14766980   PMID:15489334   PMID:17762867  


Genomics

Comparative Map Data
Necap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,653,347 - 158,665,761 (-)NCBIGRCr8
mRatBN7.25153,370,338 - 153,382,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,370,338 - 153,382,729 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,058,617 - 156,070,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,831,889 - 157,844,250 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,821,074 - 157,833,435 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,589,856 - 159,602,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,589,881 - 159,602,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,302,181 - 163,314,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,924,712 - 159,937,073 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,934,907 - 159,947,261 (-)NCBI
Celera5151,734,989 - 151,747,350 (-)NCBICelera
Cytogenetic Map5q36NCBI
NECAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,440,724 - 16,460,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,440,721 - 16,460,078 (+)EnsemblGRCh38hg38GRCh38
GRCh37116,767,219 - 16,786,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,639,820 - 16,659,160 (+)NCBINCBI36Build 36hg18NCBI36
Celera115,247,104 - 15,266,526 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,284,492 - 15,303,914 (+)NCBIHuRef
CHM1_1116,565,964 - 16,585,382 (+)NCBICHM1_1
T2T-CHM13v2.0115,882,405 - 15,901,764 (+)NCBIT2T-CHM13v2.0
Necap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,793,823 - 140,805,672 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,793,823 - 140,805,668 (-)EnsemblGRCm39 Ensembl
GRCm384141,066,512 - 141,078,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,066,512 - 141,078,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,622,427 - 140,634,260 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,338,593 - 140,350,410 (-)NCBIMGSCv36mm8
Celera4142,870,549 - 142,882,374 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.35NCBI
Necap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,885,708 - 1,900,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,885,708 - 1,900,424 (-)NCBIChiLan1.0ChiLan1.0
NECAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,460,649 - 210,480,212 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,709,336 - 209,728,893 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,578,444 - 15,597,823 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,568,847 - 16,588,213 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,568,847 - 16,588,213 (+)Ensemblpanpan1.1panPan2
NECAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,275,294 - 81,289,405 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,276,223 - 81,289,344 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,811,466 - 77,825,474 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,921,266 - 81,935,269 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,917,663 - 81,935,231 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,674,282 - 78,688,264 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,691,422 - 79,705,149 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,759,287 - 80,773,273 (-)NCBIUU_Cfam_GSD_1.0
Necap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,067,614 - 38,081,766 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,892,608 - 3,906,558 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,892,608 - 3,906,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,527,108 - 75,546,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,527,071 - 75,543,187 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,838,982 - 69,856,065 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NECAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,865,118 - 115,882,157 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,864,746 - 115,882,392 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605419,343,726 - 19,361,770 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Necap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,543,918 - 2,556,163 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,543,826 - 2,557,249 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Necap2
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:94
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000011394
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat

Markers in Region
RH129881  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,370,369 - 153,370,549 (+)MAPPERmRatBN7.2
Rnor_6.05159,589,888 - 159,590,067NCBIRnor6.0
Rnor_5.05163,302,213 - 163,302,392UniSTSRnor5.0
RGSC_v3.45159,924,719 - 159,924,898UniSTSRGSC3.4
Celera5151,734,996 - 151,735,175UniSTS
RH 3.4 Map51050.5UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 52 36 19 36 1 1 74 35 41 11 1
Low 8 5 5 5 7 10 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000011394   ⟹   ENSRNOP00000011394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,370,344 - 153,382,729 (-)Ensembl
Rnor_6.0 Ensembl5159,589,881 - 159,602,251 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100304   ⟹   ENSRNOP00000095787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,370,343 - 153,382,729 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108679   ⟹   ENSRNOP00000083128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,370,338 - 153,382,729 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108752   ⟹   ENSRNOP00000085569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,370,338 - 153,382,727 (-)Ensembl
RefSeq Acc Id: NM_001399087   ⟹   NP_001386016
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NM_001399088   ⟹   NP_001386017
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NM_001399089   ⟹   NP_001386018
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NM_001399090   ⟹   NP_001386019
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NM_199096   ⟹   NP_954527
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
Rnor_6.05159,589,881 - 159,602,241 (-)NCBI
Rnor_5.05163,302,181 - 163,314,578 (-)NCBI
RGSC_v3.45159,924,712 - 159,937,073 (-)RGD
Celera5151,734,989 - 151,747,350 (-)RGD
Sequence:
RefSeq Acc Id: NR_174157
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NR_174158
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: NR_174159
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,347 - 158,665,751 (-)NCBI
mRatBN7.25153,370,338 - 153,382,743 (-)NCBI
RefSeq Acc Id: XM_006239180   ⟹   XP_006239242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,657,091 - 158,665,761 (-)NCBI
mRatBN7.25153,374,081 - 153,382,753 (-)NCBI
Rnor_6.05159,593,593 - 159,602,260 (-)NCBI
Rnor_5.05163,302,181 - 163,314,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063287473   ⟹   XP_063143543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,653,352 - 158,665,761 (-)NCBI
RefSeq Acc Id: NP_954527   ⟸   NM_199096
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: XP_006239242   ⟸   XM_006239180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000011394   ⟸   ENSRNOT00000011394
RefSeq Acc Id: ENSRNOP00000085569   ⟸   ENSRNOT00000108752
RefSeq Acc Id: ENSRNOP00000083128   ⟸   ENSRNOT00000108679
RefSeq Acc Id: ENSRNOP00000095787   ⟸   ENSRNOT00000100304
RefSeq Acc Id: NP_001386019   ⟸   NM_001399090
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001386016   ⟸   NM_001399087
- Peptide Label: isoform 1
- UniProtKB: A0A8L2UIC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386017   ⟸   NM_001399088
- Peptide Label: isoform 2
- UniProtKB: Q6P756 (UniProtKB/Swiss-Prot),   A6ITR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386018   ⟸   NM_001399089
- Peptide Label: isoform 3
RefSeq Acc Id: XP_063143543   ⟸   XM_063287473
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A1Y0 (UniProtKB/TrEMBL)
Protein Domains
NECAP PHear

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P756-F1-model_v2 AlphaFold Q6P756 1-263 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694217
Promoter ID:EPDNEW_R4742
Type:multiple initiation site
Name:Necap2_1
Description:NECAP endocytosis associated 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05159,602,222 - 159,602,282EPDNEW
RGD ID:13694225
Promoter ID:EPDNEW_R4743
Type:multiple initiation site
Name:AC141489_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05159,606,646 - 159,606,706EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735063 AgrOrtholog
BioCyc Gene G2FUF-39368 BioCyc
Ensembl Genes ENSRNOG00000008427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055022607 UniProtKB/Swiss-Prot
  ENSRNOG00060018822 UniProtKB/Swiss-Prot
  ENSRNOG00065024891 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011394 ENTREZGENE
  ENSRNOT00000011394.6 UniProtKB/TrEMBL
  ENSRNOT00000100304 ENTREZGENE
  ENSRNOT00000100304.1 UniProtKB/Swiss-Prot
  ENSRNOT00000108679.1 UniProtKB/TrEMBL
  ENSRNOT00000108752.1 UniProtKB/TrEMBL
  ENSRNOT00055038815 UniProtKB/Swiss-Prot
  ENSRNOT00060032543 UniProtKB/Swiss-Prot
  ENSRNOT00065042828 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599028 IMAGE-MGC_LOAD
InterPro NECAP_PHear UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:298598 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72598 IMAGE-MGC_LOAD
NCBI Gene 298598 ENTREZGENE
PANTHER ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF1681 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Necap2 PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008427 RatGTEx
  ENSRNOG00055022607 RatGTEx
  ENSRNOG00060018822 RatGTEx
  ENSRNOG00065024891 RatGTEx
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZWA4_RAT UniProtKB/TrEMBL
  A0A8I6A1Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UIC7 ENTREZGENE, UniProtKB/TrEMBL
  A6ITR0 ENTREZGENE, UniProtKB/TrEMBL
  A6ITR1_RAT UniProtKB/TrEMBL
  A6ITR2_RAT UniProtKB/TrEMBL
  NECP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Necap2  NECAP endocytosis associated 2  MGC72598  Unknown (protein for MGC:72598)  Symbol and Name updated 1299863 APPROVED
2005-09-30 MGC72598        Symbol and Name status set to provisional 70820 PROVISIONAL