Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Sgta (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of SGTA mRNA] | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Sgta (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SGTA mRNA | CTD | PMID:18796159 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sgta (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SGTA mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,4,6-tribromophenol | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of SGTA mRNA | CTD | PMID:21061450 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of SGTA protein | CTD | PMID:31675489 | aflatoxin B1 | increases methylation | ISO | SGTA (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SGTA intron | CTD | PMID:30157460 | aristolochic acid A | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SGTA mRNA and aristolochic acid I results in increased expression of SGTA protein | CTD | PMID:33212167 | benzo[a]pyrene | increases expression | ISO | Sgta (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SGTA mRNA | CTD | PMID:21715664 | benzo[a]pyrene | decreases methylation | ISO | SGTA (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SGTA 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | Sgta (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of SGTA exon and Benzo(a)pyrene results in decreased methylation of SGTA intron | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | SGTA (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SGTA intron | CTD | PMID:30157460 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SGTA mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SGTA protein | CTD | PMID:37567409 | bisphenol A | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SGTA protein | CTD | PMID:31675489 | bisphenol A | decreases expression | ISO | Sgta (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SGTA mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SGTA mRNA | CTD | PMID:33296240 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of SGTA promoter | CTD | PMID:22457795 | chlorpyrifos | increases expression | ISO | Sgta (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SGTA mRNA | CTD | PMID:37019170 | copper atom | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA | CTD | PMID:24690739 | copper(II) sulfate | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SGTA mRNA | CTD | PMID:19549813 | corosolic acid | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | corosolic acid results in decreased expression of SGTA mRNA | CTD | PMID:37939859 | cyclosporin A | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SGTA mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of SGTA protein | CTD | PMID:31675489 | dibutyl phthalate | decreases expression | ISO | Sgta (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of SGTA mRNA | CTD | PMID:17361019 | disulfiram | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA | CTD | PMID:24690739 | doxorubicin | affects expression | ISO | SGTA (Homo sapiens) | 6480464 | Doxorubicin affects the expression of SGTA protein | CTD | PMID:29385562 | doxorubicin | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SGTA mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SGTA protein | CTD | PMID:23301498 | ethanol | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SGTA mRNA | CTD | PMID:29432896 | fenthion | increases expression | ISO | Sgta (Mus musculus) | 6480464 | Fenthion results in increased expression of SGTA mRNA | CTD | PMID:34813904 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SGTA mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Sgta (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of SGTA mRNA] | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | SGTA (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SGTA protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SGTA mRNA | CTD | PMID:22061828 | glycidyl methacrylate | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | glycidyl methacrylate results in increased expression of SGTA protein | CTD | PMID:36641056 | ivermectin | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SGTA protein | CTD | PMID:32959892 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of SGTA mRNA | CTD | PMID:24136188 | methapyrilene | increases methylation | ISO | SGTA (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SGTA intron | CTD | PMID:30157460 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SGTA gene | CTD | PMID:35440735 | nickel sulfate | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of SGTA mRNA | CTD | PMID:18651567 | paracetamol | decreases expression | ISO | SGTA (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SGTA mRNA | CTD | PMID:22230336 and PMID:26690555 | perfluorooctanoic acid | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of SGTA protein | CTD | PMID:26879310 | pinosylvin | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | pinosylvin results in increased expression of SGTA mRNA | CTD | PMID:23333577 | pirinixic acid | increases expression | ISO | Sgta (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SGTA mRNA | CTD | PMID:18301758 | rimonabant | multiple interactions | ISO | Sgta (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA] | CTD | PMID:19030233 | SB 431542 | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of SGTA protein | CTD | PMID:37664457 | sodium arsenite | multiple interactions | ISO | SGTA (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [SGTA protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | trans-pinosylvin | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | pinosylvin results in increased expression of SGTA mRNA | CTD | PMID:23333577 | Tributyltin oxide | increases phosphorylation | ISO | Sgta (Mus musculus) | 6480464 | bis(tri-n-butyltin)oxide results in increased phosphorylation of SGTA protein | CTD | PMID:22174045 | urethane | increases expression | ISO | SGTA (Homo sapiens) | 6480464 | Urethane results in increased expression of SGTA mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | SGTA (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SGTA gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Sgta (Mus musculus) | 6480464 | Valproic Acid affects the expression of SGTA mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | Sgta (Mus musculus) | 6480464 | Valproic Acid results in increased expression of SGTA mRNA | CTD | PMID:21427059 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SGTA mRNA | CTD | PMID:19015723 | |