Hapln1 (hyaluronan and proteoglycan link protein 1) - Rat Genome Database

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Gene: Hapln1 (hyaluronan and proteoglycan link protein 1) Rattus norvegicus
Analyze
Symbol: Hapln1
Name: hyaluronan and proteoglycan link protein 1
RGD ID: 2412
Description: Predicted to enable hyaluronic acid binding activity and structural molecule activity. Predicted to be involved in nervous system development; positive regulation of neuroblast proliferation; and skeletal system development. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space; perineuronal net; and synapse. Orthologous to human HAPLN1 (hyaluronan and proteoglycan link protein 1); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cartilage link protein 1; cartilage-link protein; cartilage-linking protein 1; Crtl1; LP; MGC156657; proteoglycan link protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8222,366,967 - 22,431,709 (+)NCBIGRCr8
mRatBN7.2220,631,640 - 20,696,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl220,631,640 - 20,693,777 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx227,664,677 - 27,726,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0225,764,967 - 25,827,103 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0220,559,986 - 20,622,189 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0218,354,542 - 18,419,077 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl218,354,542 - 18,419,071 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0218,229,924 - 18,294,459 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4219,576,064 - 19,638,106 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1219,534,388 - 19,557,456 (+)NCBI
Celera216,774,532 - 16,836,586 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dimethylhydrazine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-D  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cytarabine  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
fructose  (ISO)
glucose  (ISO)
lithium chloride  (ISO)
maneb  (ISO)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
phenylmercury acetate  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (EXP)
streptozocin  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Link protein cDNA sequence reveals a tandemly repeated protein structure. Doege K, etal., Proc Natl Acad Sci U S A 1986 Jun;83(11):3761-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Alternative splicing generates two different mRNA species for rat link protein. Rhodes C, etal., J Biol Chem 1988 May 5;263(13):6063-7.
9. Follicle-stimulating hormone and insulin-like growth factor I synergistically induce up-regulation of cartilage link protein (Crtl1) via activation of phosphatidylinositol-dependent kinase/Akt in rat granulosa cells. Sun GW, etal., Endocrinology 2003 Mar;144(3):793-801.
10. Mice lacking link protein develop dwarfism and craniofacial abnormalities. Watanabe H and Yamada Y, Nat Genet 1999 Feb;21(2):225-9.
Additional References at PubMed
PMID:2419334   PMID:12477932   PMID:14620382   PMID:17206619   PMID:20339004   PMID:20551380   PMID:20566484   PMID:22206666   PMID:23979707   PMID:24534009   PMID:27068509   PMID:29476059  
PMID:36737556   PMID:38580957  


Genomics

Comparative Map Data
Hapln1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8222,366,967 - 22,431,709 (+)NCBIGRCr8
mRatBN7.2220,631,640 - 20,696,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl220,631,640 - 20,693,777 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx227,664,677 - 27,726,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0225,764,967 - 25,827,103 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0220,559,986 - 20,622,189 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0218,354,542 - 18,419,077 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl218,354,542 - 18,419,071 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0218,229,924 - 18,294,459 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4219,576,064 - 19,638,106 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1219,534,388 - 19,557,456 (+)NCBI
Celera216,774,532 - 16,836,586 (+)NCBICelera
Cytogenetic Map2q12NCBI
HAPLN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38583,637,805 - 83,720,855 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl583,637,805 - 83,720,855 (-)EnsemblGRCh38hg38GRCh38
GRCh37582,933,624 - 83,016,674 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36582,972,493 - 83,052,454 (-)NCBINCBI36Build 36hg18NCBI36
Build 34582,972,500 - 83,052,454NCBI
Celera578,839,034 - 78,921,911 (-)NCBICelera
Cytogenetic Map5q14.3NCBI
HuRef578,141,962 - 78,224,830 (-)NCBIHuRef
CHM1_1582,366,947 - 82,449,878 (-)NCBICHM1_1
T2T-CHM13v2.0584,126,276 - 84,209,363 (-)NCBIT2T-CHM13v2.0
Hapln1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391389,688,654 - 89,759,951 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1389,687,915 - 89,759,771 (+)EnsemblGRCm39 Ensembl
GRCm381389,540,529 - 89,611,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1389,539,796 - 89,611,652 (+)EnsemblGRCm38mm10GRCm38
MGSCv371389,680,241 - 89,751,437 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361390,014,993 - 90,085,856 (+)NCBIMGSCv36mm8
Celera1393,138,718 - 93,209,423 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1345.5NCBI
Hapln1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541826,848,303 - 26,913,339 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541826,848,302 - 26,912,151 (+)NCBIChiLan1.0ChiLan1.0
HAPLN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2431,581,888 - 31,665,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1529,735,513 - 29,817,401 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0531,560,282 - 31,643,138 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1531,879,669 - 31,963,636 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl531,879,276 - 31,964,562 (+)Ensemblpanpan1.1panPan2
HAPLN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1323,999,148 - 24,077,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl323,998,545 - 24,074,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha325,237,411 - 25,313,949 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0323,898,912 - 23,975,479 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl323,932,039 - 23,977,175 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1323,855,989 - 23,944,815 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0323,828,709 - 23,905,165 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0324,115,889 - 24,192,354 (+)NCBIUU_Cfam_GSD_1.0
Hapln1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213179,817,517 - 179,882,913 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364692,742,846 - 2,808,123 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364692,745,568 - 2,772,789 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAPLN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl291,857,582 - 91,907,351 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1291,857,495 - 91,935,485 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2293,941,323 - 94,019,486 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HAPLN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1477,746,505 - 77,831,509 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604926,655,535 - 26,739,732 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hapln1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247433,789,757 - 3,855,107 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247433,789,999 - 3,855,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hapln1
386 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:460
Count of miRNA genes:206
Interacting mature miRNAs:254
Transcripts:ENSRNOT00000042958, ENSRNOT00000043196
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
61368Mcs1Mammary carcinoma susceptibility QTL 14.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777223319447Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat

Markers in Region
BE103548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2220,693,555 - 20,693,740 (+)MAPPERmRatBN7.2
Rnor_6.0218,416,245 - 18,416,429NCBIRnor6.0
Rnor_5.0218,291,627 - 18,291,811UniSTSRnor5.0
RGSC_v3.4219,637,881 - 19,638,065UniSTSRGSC3.4
Celera216,836,361 - 16,836,545UniSTS
Cytogenetic Map2q12UniSTS
CRTL1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2220,685,377 - 20,685,623 (+)MAPPERmRatBN7.2
Rnor_6.0218,408,066 - 18,408,311NCBIRnor6.0
Rnor_5.0218,283,448 - 18,283,693UniSTSRnor5.0
RGSC_v3.4219,629,701 - 19,629,946UniSTSRGSC3.4
Celera216,828,206 - 16,828,451UniSTS
Cytogenetic Map2q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 16 4 4 4 35 10 15
Low 2 22 7 6 6 39 14 13 8
Below cutoff 1 5 25 13 15 13 7 8 11 10 1 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000042958   ⟹   ENSRNOP00000045959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl220,631,640 - 20,693,777 (+)Ensembl
Rnor_6.0 Ensembl218,354,542 - 18,416,466 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000043196   ⟹   ENSRNOP00000040553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl218,392,142 - 18,419,071 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108518   ⟹   ENSRNOP00000094436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl220,669,600 - 20,693,777 (+)Ensembl
RefSeq Acc Id: NM_019189   ⟹   NP_062062
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8222,366,967 - 22,429,102 (+)NCBI
mRatBN7.2220,631,640 - 20,693,781 (+)NCBI
Rnor_6.0218,354,542 - 18,416,470 (+)NCBI
Rnor_5.0218,229,924 - 18,294,459 (+)NCBI
RGSC_v3.4219,576,064 - 19,638,106 (+)RGD
Celera216,774,532 - 16,836,586 (+)RGD
Sequence:
RefSeq Acc Id: XM_006231748   ⟹   XP_006231810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8222,404,138 - 22,431,709 (+)NCBI
mRatBN7.2220,668,807 - 20,696,388 (+)NCBI
Rnor_6.0218,391,649 - 18,419,077 (+)NCBI
Rnor_5.0218,229,924 - 18,294,459 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101883   ⟹   XP_038957811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8222,404,486 - 22,431,709 (+)NCBI
mRatBN7.2220,669,232 - 20,696,388 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_062062   ⟸   NM_019189
- Peptide Label: precursor
- UniProtKB: A1A5N6 (UniProtKB/TrEMBL),   A6I4N0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231810   ⟸   XM_006231748
- Peptide Label: isoform X1
- UniProtKB: P03994 (UniProtKB/Swiss-Prot),   A6I4N0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040553   ⟸   ENSRNOT00000043196
RefSeq Acc Id: ENSRNOP00000045959   ⟸   ENSRNOT00000042958
RefSeq Acc Id: XP_038957811   ⟸   XM_039101883
- Peptide Label: isoform X1
- UniProtKB: P03994 (UniProtKB/Swiss-Prot),   A6I4N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000094436   ⟸   ENSRNOT00000108518
Protein Domains
Ig-like   Ig-like V-type   Link

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P03994-F1-model_v2 AlphaFold P03994 1-354 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691051
Promoter ID:EPDNEW_R1576
Type:single initiation site
Name:Hapln1_1
Description:hyaluronan and proteoglycan link protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0218,354,529 - 18,354,589EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2412 AgrOrtholog
BioCyc Gene G2FUF-54904 BioCyc
Ensembl Genes ENSRNOG00000032002 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055004102 UniProtKB/Swiss-Prot
  ENSRNOG00060000748 UniProtKB/Swiss-Prot
  ENSRNOG00065022253 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042958 ENTREZGENE
  ENSRNOT00000042958.6 UniProtKB/Swiss-Prot
  ENSRNOT00000108518.1 UniProtKB/Swiss-Prot
  ENSRNOT00055006549 UniProtKB/Swiss-Prot
  ENSRNOT00060000887 UniProtKB/Swiss-Prot
  ENSRNOT00065037937 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8371477 IMAGE-MGC_LOAD
InterPro C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Link_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29331 UniProtKB/TrEMBL
MGC_CLONE MGC:156657 IMAGE-MGC_LOAD
NCBI Gene 29331 ENTREZGENE
PANTHER AGGRECAN/VERSICAN PROTEOGLYCAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Xlink UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hapln1 PhenoGen
PRINTS LINKMODULE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LINK_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LINK_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032002 RatGTEx
  ENSRNOG00055004102 RatGTEx
  ENSRNOG00060000748 RatGTEx
  ENSRNOG00065022253 RatGTEx
SMART IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LINK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1A5N6 ENTREZGENE, UniProtKB/TrEMBL
  A6I4N0 ENTREZGENE, UniProtKB/TrEMBL
  HPLN1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Hapln1  hyaluronan and proteoglycan link protein 1  Crtl1  cartilage link protein 1   Symbol and Name updated 1299863 APPROVED
2002-06-10 Crtl1  cartilage link protein 1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression in granulosa cells increases in response to follicle-stimulating hormone and insulin-like growth factor 633558
gene_expression expressed in cartilage 69818