Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1,2-dichloroethane | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of SRP9 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SRP9 mRNA | CTD | PMID:22206623 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 17alpha-ethynylestradiol | affects expression | ISO | Srp9 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of SRP9 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SRP9 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of SRP9 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of SRP9 mRNA | CTD | PMID:26496021 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Srp9 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SRP9 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SRP9 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Srp9 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SRP9 mRNA | CTD | PMID:21570461 | 2-methylcholine | affects expression | ISO | SRP9 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of SRP9 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SRP9 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of SRP9 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SRP9 mRNA | CTD | PMID:36041667 | 4-hydroxynon-2-enal | affects binding | ISO | SRP9 (Homo sapiens) | 6480464 | SRP9 protein binds to 4-hydroxy-2-nonenal | CTD | PMID:20043646 | 5-fluorouracil | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Fluorouracil results in decreased expression of SRP9 mRNA] | CTD | PMID:15016801 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SRP9 mRNA | CTD | PMID:30047161 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SRP9 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SRP9 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SRP9 mRNA] | CTD | PMID:32406909 | atrazine | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SRP9 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SRP9 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | SRP9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SRP9 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SRP9 mRNA | CTD | PMID:15034205 and PMID:20504355 | benzo[a]pyrene | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of SRP9 mRNA] | CTD | PMID:15034205 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SRP9 mRNA and [bisphenol A co-treated with Estradiol] results in decreased expression of SRP9 mRNA | CTD | PMID:26496021 and PMID:36041667 | bisphenol A | increases expression | ISO | SRP9 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SRP9 protein | CTD | PMID:34186270 | bisphenol A | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SRP9 mRNA | CTD | PMID:29275510 and PMID:33670352 | bisphenol A | affects expression | ISO | SRP9 (Homo sapiens) | 6480464 | bisphenol A affects the expression of SRP9 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SRP9 gene | CTD | PMID:28505145 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SRP9 mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SRP9 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SRP9 mRNA | CTD | PMID:36041667 | caffeine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | calyculin a | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | calyculin A results in decreased expression of SRP9 mRNA | CTD | PMID:25270620 | carbon nanotube | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of SRP9 mRNA | CTD | PMID:25554681 and PMID:25620056 | CGP 52608 | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SRP9 gene] | CTD | PMID:28238834 | chlorohydrocarbon | decreases expression | EXP | | 6480464 | Hydrocarbons and Chlorinated results in decreased expression of SRP9 mRNA | CTD | PMID:18077114 | chloropicrin | increases expression | ISO | SRP9 (Homo sapiens) | 6480464 | chloropicrin results in increased expression of SRP9 mRNA | CTD | PMID:26352163 | chrysene | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | chrysene results in decreased expression of SRP9 mRNA | CTD | PMID:26377693 | cisplatin | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of SRP9 mRNA | CTD | PMID:27392435 | clotrimazole | increases expression | EXP | | 6480464 | Clotrimazole results in increased expression of SRP9 mRNA | CTD | PMID:30047161 | copper(II) sulfate | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SRP9 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SRP9 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SRP9 mRNA | CTD | PMID:28628672 | dextran sulfate | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | Erianin inhibits the reaction [Dextran Sulfate results in increased expression of SRP9 protein] | CTD | PMID:32272095 | dextran sulfate | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Dextran Sulfate results in increased expression of SRP9 protein | CTD | PMID:32272095 | dibenzo[a,l]pyrene | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | dibenzo(a and l)pyrene results in decreased expression of SRP9 mRNA | CTD | PMID:25908611 | dicrotophos | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SRP9 mRNA | CTD | PMID:28302478 | doxorubicin | affects expression | ISO | SRP9 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of SRP9 protein | CTD | PMID:29385562 | enzyme inhibitor | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SRP9 protein | CTD | PMID:23301498 | epoxiconazole | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of SRP9 mRNA | CTD | PMID:35436446 | ethanol | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of SRP9 mRNA | CTD | PMID:29432896 | ferroheme b | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Heme metabolite results in increased expression of SRP9 mRNA | CTD | PMID:19191707 | folic acid | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SRP9 mRNA | CTD | PMID:22206623 | fonofos | decreases methylation | ISO | SRP9 (Homo sapiens) | 6480464 | Fonofos results in decreased methylation of SRP9 promoter | CTD | PMID:22847954 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of SRP9 mRNA | CTD | PMID:24136188 | gold atom | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Gold results in decreased expression of SRP9 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Gold results in decreased expression of SRP9 mRNA | CTD | PMID:25523186 | heme b | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Heme metabolite results in increased expression of SRP9 mRNA | CTD | PMID:19191707 | hydralazine | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of SRP9 mRNA | CTD | PMID:17183730 | indometacin | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SRP9 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SRP9 protein | CTD | PMID:32959892 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SRP9 mRNA | CTD | PMID:30047161 | nicotine | multiple interactions | ISO | Srp9 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | ozone | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of SRP9 mRNA | CTD | PMID:35430440 | parathion | decreases methylation | ISO | SRP9 (Homo sapiens) | 6480464 | Parathion results in decreased methylation of SRP9 promoter | CTD | PMID:22847954 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SRP9 mRNA | CTD | PMID:27153767 | perfluorooctanoic acid | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of SRP9 protein | CTD | PMID:26879310 | propiconazole | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | propiconazole results in increased expression of SRP9 mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SRP9 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Rotenone results in increased expression of SRP9 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of SRP9 protein | CTD | PMID:37664457 | sodium fluoride | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of SRP9 mRNA | CTD | PMID:27862939 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SRP9 mRNA | CTD | PMID:30047161 | tamoxifen | affects expression | ISO | Srp9 (Mus musculus) | 6480464 | Tamoxifen affects the expression of SRP9 mRNA | CTD | PMID:17555576 | terbufos | decreases methylation | ISO | SRP9 (Homo sapiens) | 6480464 | terbufos results in decreased methylation of SRP9 promoter | CTD | PMID:22847954 | tetrachloromethane | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SRP9 mRNA | CTD | PMID:31919559 | titanium dioxide | decreases expression | ISO | Srp9 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SRP9 mRNA | CTD | PMID:19464567 | titanium dioxide | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SRP9 mRNA | CTD | PMID:23557971 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of SRP9 gene | CTD | PMID:27618143 | tungsten | increases expression | ISO | Srp9 (Mus musculus) | 6480464 | Tungsten results in increased expression of SRP9 mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | SRP9 (Homo sapiens) | 6480464 | Urethane results in decreased expression of SRP9 mRNA | CTD | PMID:28818685 | valproic acid | multiple interactions | ISO | SRP9 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of SRP9 mRNA | CTD | PMID:17183730 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SRP9 mRNA | CTD | PMID:23034163 | |