Sh3bgr (SH3 domain binding glutamate-rich protein)

Gene: Sh3bgr (SH3 domain binding glutamate-rich protein) Rattus norvegicus

Analyze

Symbol:

Sh3bgr

Name:

SH3 domain binding glutamate-rich protein

RGD ID:

1563599

Description:

Predicted to be active in cytoplasm. Orthologous to human SH3BGR (SH3 domain binding glutamate rich protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC102553613; LOC498066; RGD1563599; SH3 domain binding glutamic acid-rich protein; SH3 domain-binding glutamic acid-rich protein; SH3 domain-binding glutamic acid-rich protein-like; SH3-binding domain glutamic acid-rich protein; similar to putative SH3BGR protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	48,973,033 - 48,997,328 (+)	NCBI		GRCr8
mRatBN7.2	11	35,503,663 - 35,527,853 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	35,503,725 - 35,527,853 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	44,160,745 - 44,184,889 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	36,832,126 - 36,856,270 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	35,978,116 - 36,002,181 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	36,555,354 - 36,579,537 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	36,555,416 - 36,579,535 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	40,086,045 - 40,110,164 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	36,511,326 - 36,535,444 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	11	32,944,120 - 32,968,430 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP)

cantharidin (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chrysene (ISO)

cisplatin (EXP)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

dibutyl phthalate (EXP,ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethyl methanesulfonate (ISO)

gentamycin (EXP)

glucose (ISO)

hydroquinone (ISO)

lead(0) (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylseleninic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

octadecanoic acid (ISO)

ozone (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

pirinixic acid (ISO)

quercetin (ISO)

rotenone (EXP)

SB 431542 (ISO)

sunitinib (ISO)

Tetrachlorobisphenol A (ISO)

thalidomide (ISO)

titanium dioxide (ISO)

toluene (EXP)

triclosan (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16780588

Genomics

Comparative Map Data

Sh3bgr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	48,973,033 - 48,997,328 (+)	NCBI		GRCr8
mRatBN7.2	11	35,503,663 - 35,527,853 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	35,503,725 - 35,527,853 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	44,160,745 - 44,184,889 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	36,832,126 - 36,856,270 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	35,978,116 - 36,002,181 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	36,555,354 - 36,579,537 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	36,555,416 - 36,579,535 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	40,086,045 - 40,110,164 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	36,511,326 - 36,535,444 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	11	32,944,120 - 32,968,430 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

SH3BGR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	39,445,865 - 39,515,506 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	39,445,855 - 39,515,506 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	40,817,791 - 40,887,433 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	39,739,667 - 39,809,303 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	39,745,649 - 39,809,302	NCBI
Celera	21	26,015,495 - 26,085,127 (+)	NCBI		Celera
Cytogenetic Map	21	q22.2	NCBI
HuRef	21	26,286,675 - 26,357,208 (+)	NCBI		HuRef
CHM1_1	21	40,378,935 - 40,448,548 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	37,830,488 - 37,900,126 (+)	NCBI		T2T-CHM13v2.0

Sh3bgr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	96,001,670 - 96,030,133 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	96,001,650 - 96,030,135 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	96,200,470 - 96,228,933 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	96,200,450 - 96,228,935 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	96,422,077 - 96,450,540 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	96,305,614 - 96,329,470 (+)	NCBI		MGSCv36	mm8
Celera	16	97,274,391 - 97,301,969 (+)	NCBI		Celera
Cytogenetic Map	16	C4	NCBI
cM Map	16	56.86	NCBI

Sh3bgr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	38,225,718 - 38,258,125 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	38,225,827 - 38,265,792 (+)	NCBI	ChiLan1.0	ChiLan1.0

SH3BGR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	35,543,418 - 35,613,655 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	30,399,318 - 30,469,759 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	25,798,888 - 25,869,102 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	39,142,685 - 39,205,414 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	39,142,685 - 39,205,402 (+)	Ensembl	panpan1.1		panPan2

LOC119867070
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	31	33,495,810 - 33,551,676 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	33,729,949 - 33,785,714 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	33,729,957 - 33,785,659 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	33,601,873 - 33,657,248 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	33,606,662 - 33,662,604 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	34,098,099 - 34,153,975 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101973230
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	33,628,715 - 33,767,203 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	3,703,846 - 3,751,278 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936500	3,814,904 - 3,831,935 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936500	3,700,620 - 3,751,532 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SH3BGR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	203,046,553 - 203,108,634 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	203,046,575 - 203,108,638 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	213,286,145 - 213,348,193 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103218923
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	83,395,130 - 83,458,485 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	83,325,899 - 83,342,185 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
ChlSab1.1 Ensembl	2	83,401,732 - 83,455,416 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	11,185,960 - 11,318,122 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sh3bgr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624745	24,538,069 - 24,574,036 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sh3bgr
168 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	121
Count of miRNA genes:	97
Interacting mature miRNAs:	103
Transcripts:	ENSRNOT00000064981
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
1641927	Alcrsp10	Alcohol response QTL 10			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	11	8436674	53436674	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	16472047	44285911	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	29528418	60324829	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat

Markers in Region

RH127121

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Celera	11	32,944,129 - 32,944,362	UniSTS
Cytogenetic Map	11	q11	UniSTS

BE111713

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	35,521,632 - 35,521,788 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	36,573,317 - 36,573,472	NCBI	Rnor6.0
Rnor_5.0	11	40,103,944 - 40,104,099	UniSTS	Rnor5.0
RGSC_v3.4	11	36,529,226 - 36,529,381	UniSTS	RGSC3.4
RH 3.4 Map	11	266.5	UniSTS
Cytogenetic Map	11	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High								1
Medium	3	43					8	10	6		6	7	8
Low			43	27	19	27			68	35	35	4
Below cutoff			14	14		14

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC142178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC159440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000047347 ⟹ ENSRNOP00000045652

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	35,503,725 - 35,527,851 (+)	Ensembl
Rnor_6.0 Ensembl	11	39,435,291 - 39,448,503 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000064981 ⟹ ENSRNOP00000063900

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	35,503,725 - 35,527,851 (+)	Ensembl
Rnor_6.0 Ensembl	11	36,555,416 - 36,579,535 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096343 ⟹ ENSRNOP00000097064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	35,508,902 - 35,520,585 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000119421 ⟹ ENSRNOP00000084404

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	35,508,107 - 35,527,853 (+)	Ensembl

RefSeq Acc Id:

NM_001127682 ⟹ NP_001121154

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,205 - 48,997,326 (+)	NCBI
mRatBN7.2	11	35,503,725 - 35,527,851 (+)	NCBI
Rnor_6.0	11	36,555,416 - 36,579,535 (+)	NCBI
Rnor_5.0	11	40,086,045 - 40,110,164 (+)	NCBI
RGSC_v3.4	11	36,511,326 - 36,535,444 (+)	RGD
Celera	11	32,944,120 - 32,968,430 (-)	RGD

Sequence:

show sequence

TGGTTGGAGGGGAGGGTTGGGAGCAGTGGCTTGGATCACAGCCAGCGCTGACCTGGCACCTGCT
CCCCCAGCGTCACTGCGGGATTTGTCCAGCGACTTCCCTAGCAGGGGTGTGTTAGGGGGAGTCC
TCTTTCCGACTGTCGAAATGGTTATCAAAGTGTTTGTTGCCACATCTTCTGGGTCCATAGCGAT
TAGGAAAAAACAGCAAGAAGTGGTGGGCTTTTTGGAAGCCAATAAAATAGACTTTAAGGAGCTG
GACATAGCCGGGGATGAAGACAACAGGAAGTGGATGAGAGAGAACGTTCCTGGGGAGAAGAAGC
CTCAGAATGGGATTCCTTTACCTCCTCAGATCTTCAACGAAGAGCAGTATTGTGGGGATTTTGA
CTCTTTCTTCTCTGCAAAAGAAGAAAATATTATTTATTCATTCCTTGGTCTGGCTCCCCCTCCT
GGGTCAAAGGTGACAAAATCTGAGGAAGCGTCTTCCCTTCCCAATGGAGATGTAGCAGGAGAGG
CAGAGGGGGCTGCAGAGGGAACAGAGAAGGCTGAAGAAAGTGGAGAAACTGAGGCACAGAAAGA
GGACAGTGAAGACACTGGCGAGCTTTCTCAATCCCAAGAGAAGAAGACGGAAGAGGCAACAGAG
GGAGGAGCAGAGGGAGAAGCTGAAGAAGAACCCGAGGAAGAGGGAGGAGAAGAGGAAGATTCTT
AGGCTTTTCAGGCTGGTGCCTCAACTTTCCCAGGATATTCAAGCCTCAAGGCCACATTTGAACT
CTCTCTCCTCCTTTAACTCTATGAAATACTCAGCTGGAAGCCAGCCCCCTTCCCCCAGCACCCC
TGGGTTCACCGAGGACCCGTGCCCTCCGAAACAGCTTGGTGTATGTGAATCCCTATCTCACCGT
GTCAACATGAGGCTGGATGTGAAGACAGCACACATGCTGTGCCTACGGTTTATGCTCTTTGCTT
AATGTTTGTTTCCTCTGCTGCCCACAAGTAGACCTTCTCGTTAATACTCTGCAAACGGGATCTT
GAGGCGTAGTTTCTCTCTGTGATGCGGCCGAAGGATTTCTTTGTGTACCCGCTTGTTTTAGGCT
TGGCTTTCAAAACAAAACACTTCCCAGAGAGCAATCATCAATAAAGATTGATAGCAAG

hide sequence

RefSeq Acc Id:

XM_006248184 ⟹ XP_006248246

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,033 - 48,997,328 (+)	NCBI
mRatBN7.2	11	35,503,663 - 35,527,853 (+)	NCBI
Rnor_6.0	11	36,555,354 - 36,579,537 (+)	NCBI
Rnor_5.0	11	40,086,045 - 40,110,164 (+)	NCBI

Sequence:

show sequence

CTTGACATCCCAAACGGAGGGGGAAGCCCAGGATGCCTCCCTGTTACTCTTGGTTAACCTCTTG
GTTGGAGGGGAGGGTTGGGAGCAGTGGCTTGGATCACAGCCAGCGCTGACCTGGCACCTGCTCC
CCCAGCGTCACTGCGGGATTTGTCCAGCGACTTCCCTAGCAGGGGTGTGTTAGGGGGAGTCCTC
TTTCCGACTGTCGAAATGGTTATCAAAGTGTTTGTTGCCACATCTTCTGGGTCCATAGCGATTA
GGAAAAAACAGCAAGAAGTGGTGGGCTTTTTGGAAGCCAATAAAATAGACTTTAAGGAGCTGGA
CATAGCCGGGGATGAAGACAACAGGAAGTGGATGAGAGAGAACGTTCCTGGGGAGAAGAAGCCT
CAGAATGGGATTCCTTTACCTCCTCAGATCTTCAACGAAGAGCAGTATTGTGGGGATTTTGACT
CTTTCTTCTCTGCAAAAGAAGAAAATATTATTTATTCATTCCTTGGTCTGGCTCCCCCTCCTGG
GTCAAAGGTGACAAAATCTGAGGAAGCGTCTTCCCTTCCCAATGGAGATGTAGCAGGAGAGGCA
GAGGGGGCTGCAGAGGGAACAGAGAAGGCTGAAGAAAGTGGAGAAACTGAGGCACAGAAAGAGG
ACAGTGAAGACACTGGCGAGCTTTCTCAATCCCAAGAGAAGAAGGAAGAAGAGGGAGAAGAGGG
AGAAAAGGGAGAAGAGGGAGAGACAGCAGAAGAGACGGAAGAGGCAACAGAGGGAGGAGCAGAG
GGAGAAGCTGAAGAAGAACCCGAGGAAGAGGGAGGAGAAGAGGAAGATTCTTAGGCTTTTCAGG
CTGGTGCCTCAACTTTCCCAGGATATTCAAGCCTCAAGGCCACATTTGAACTCTCTCTCCTCCT
TTAACTCTATGAAATACTCAGCTGGAAGCCAGCCCCCTTCCCCCAGCACCCCTGGGTTCACCGA
GGACCCGTGCCCTCCGAAACAGCTTGGTGTATGTGAATCCCTATCTCACCGTGTCAACATGAGG
CTGGATGTGAAGACAGCACACATGCTGTGCCTACGGTTTATGCTCTTTGCTTAATGTTTGTTTC
CTCTGCTGCCCACAAGTAGACCTTCTCGTTAATACTCTGCAAACGGGATCTTGAGGCGTAGTTT
CTCTCTGTGATGCGGCCGAAGGATTTCTTTGTGTACCCGCTTGTTTTAGGCTTGGCTTTCAAAA
CAAAACACTTCCCAGAGAGCAATCATCAATAAAGATTGATAGCAAGAA

hide sequence

RefSeq Acc Id:

XM_039088574 ⟹ XP_038944502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,352 - 48,997,328 (+)	NCBI
mRatBN7.2	11	35,503,990 - 35,527,853 (+)	NCBI

RefSeq Acc Id:

XM_039088575 ⟹ XP_038944503

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,138 - 48,997,328 (+)	NCBI
mRatBN7.2	11	35,503,695 - 35,527,853 (+)	NCBI

RefSeq Acc Id:

XM_063270698 ⟹ XP_063126768

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,102 - 48,993,936 (+)	NCBI

RefSeq Acc Id:

XM_063270699 ⟹ XP_063126769

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	48,973,481 - 48,997,328 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001121154	(Get FASTA)	NCBI Sequence Viewer
	XP_006248246	(Get FASTA)	NCBI Sequence Viewer
	XP_038944502	(Get FASTA)	NCBI Sequence Viewer
	XP_038944503	(Get FASTA)	NCBI Sequence Viewer
	XP_063126768	(Get FASTA)	NCBI Sequence Viewer
	XP_063126769	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI59441	(Get FASTA)	NCBI Sequence Viewer
	EDL76659	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045652.6
	ENSRNOP00000063900
	ENSRNOP00000063900.1
	ENSRNOP00000084404
	ENSRNOP00000084404.1
	ENSRNOP00000097064.1

RefSeq Acc Id:	NP_001121154 ⟸ NM_001127682
- UniProtKB:	D3ZU20 (UniProtKB/TrEMBL), A6KPR6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRKWMRENVPGEKKPQNGIP LPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSEEASSLPNGDVAGEAEGAAE GTEKAEESGETEAQKEDSEDTGELSQSQEKKTEEATEGGAEGEAEEEPEEEGGEEEDS hide sequence

RefSeq Acc Id:	XP_006248246 ⟸ XM_006248184
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZZ80 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRKWMRENVPGEKKPQNGIP LPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSEEASSLPNGDVAGEAEGAAE GTEKAEESGETEAQKEDSEDTGELSQSQEKKEEEGEEGEKGEEGETAEETEEATEGGAEGEAEE EPEEEGGEEEDS hide sequence

RefSeq Acc Id:

ENSRNOP00000063900 ⟸ ENSRNOT00000064981

RefSeq Acc Id:	XP_038944503 ⟸ XM_039088575
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5ZZ80 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038944502 ⟸ XM_039088574
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZZ80 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000045652 ⟸ ENSRNOT00000047347

RefSeq Acc Id:

ENSRNOP00000097064 ⟸ ENSRNOT00000096343

RefSeq Acc Id:

ENSRNOP00000084404 ⟸ ENSRNOT00000119421

RefSeq Acc Id:	XP_063126768 ⟸ XM_063270698
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063126769 ⟸ XM_063270699
- Peptide Label:	isoform X4

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AAC3-F1-model_v2	AlphaFold	D4AAC3	1-107	view protein structure
AF-D3ZU20-F1-model_v2	AlphaFold	D3ZU20	1-186	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563599	AgrOrtholog
BioCyc Gene	G2FUF-21710	BioCyc
Ensembl Genes	ENSRNOG00000028238	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000046133	Ensembl
Ensembl Transcript	ENSRNOT00000047347.6	UniProtKB/TrEMBL
	ENSRNOT00000064981	ENTREZGENE
	ENSRNOT00000064981.4	UniProtKB/TrEMBL
	ENSRNOT00000096343.1	UniProtKB/TrEMBL
	ENSRNOT00000119421.1	UniProtKB/TrEMBL
Gene3D-CATH	Glutaredoxin	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9035279	IMAGE-MGC_LOAD
InterPro	Glut_rich_SH3-bd	UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/TrEMBL
KEGG Report	rno:498066	UniProtKB/TrEMBL
MGC_CLONE	MGC:188790	IMAGE-MGC_LOAD
NCBI Gene	498066	ENTREZGENE
PANTHER	SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN	UniProtKB/TrEMBL
	SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN	UniProtKB/TrEMBL
Pfam	SH3BGR	UniProtKB/TrEMBL
PhenoGen	Sh3bgr	PhenoGen
RatGTEx	ENSRNOG00000028238	RatGTEx
	ENSRNOG00000046133	RatGTEx
Superfamily-SCOP	Thiordxn-like_fd	UniProtKB/TrEMBL
UniProt	A0A8I5ZZ80	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AVY1_RAT	UniProtKB/TrEMBL
	A6KPR6	ENTREZGENE, UniProtKB/TrEMBL
	B0K040_RAT	UniProtKB/TrEMBL
	D3ZU20	ENTREZGENE, UniProtKB/TrEMBL
	D4AAC3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Sh3bgr	SH3 domain binding glutamate-rich protein	LOC102553613	SH3 domain-binding glutamic acid-rich protein-like	Data merged from RGD:7616949	737654	PROVISIONAL
2014-03-13	Sh3bgr	SH3 domain binding glutamate-rich protein	Sh3bgr	SH3 domain binding glutamic acid-rich protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-18	LOC102553613	SH3 domain-binding glutamic acid-rich protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-11-04	Sh3bgr	SH3 domain binding glutamic acid-rich protein	Sh3bgr	SH3-binding domain glutamic acid-rich protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Sh3bgr	SH3-binding domain glutamic acid-rich protein	RGD1563599_predicted	similar to putative SH3BGR protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1563599_predicted	similar to putative SH3BGR protein (predicted)	LOC498066	similar to putative SH3BGR protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498066	similar to putative SH3BGR protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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