Nap1l2 (nucleosome assembly protein 1-like 2) - Rat Genome Database

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Gene: Nap1l2 (nucleosome assembly protein 1-like 2) Rattus norvegicus
Analyze
Symbol: Nap1l2 (Ensembl: AABR07039336.2)
Name: nucleosome assembly protein 1-like 2
RGD ID: 1563260
Description: Predicted to enable chromatin binding activity; histone acetyltransferase regulator activity; and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to act upstream of or within positive regulation of neuron differentiation and regulation of stem cell division. Predicted to be located in nucleus. Orthologous to human NAP1L2 (nucleosome assembly protein 1 like 2); INTERACTS WITH acetamide; bisphenol A; diuron.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC317247; similar to Nap1l2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X72,239,849 - 72,242,247 (-)NCBIGRCr8
mRatBN7.2X68,174,051 - 68,176,449 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX68,173,987 - 68,176,666 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,683,266 - 69,685,664 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X73,183,508 - 73,185,906 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,744,694 - 70,747,092 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X73,997,274 - 73,999,677 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X74,802,169 - 74,804,572 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X91,127,838 - 91,130,238 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX69,542,224 - 69,544,622 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:17591696  


Genomics

Comparative Map Data
Nap1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X72,239,849 - 72,242,247 (-)NCBIGRCr8
mRatBN7.2X68,174,051 - 68,176,449 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX68,173,987 - 68,176,666 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,683,266 - 69,685,664 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X73,183,508 - 73,185,906 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,744,694 - 70,747,092 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X73,997,274 - 73,999,677 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X74,802,169 - 74,804,572 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X91,127,838 - 91,130,238 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX69,542,224 - 69,544,622 (-)NCBICelera
Cytogenetic MapXq22NCBI
NAP1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X73,212,299 - 73,214,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX73,212,299 - 73,214,851 (-)EnsemblGRCh38hg38GRCh38
GRCh37X72,432,135 - 72,434,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X72,348,879 - 72,351,409 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X72,215,175 - 72,217,705NCBI
CeleraX72,715,677 - 72,718,207 (-)NCBICelera
Cytogenetic MapXq13.2NCBI
HuRefX66,066,610 - 66,069,053 (-)NCBIHuRef
CHM1_1X72,324,734 - 72,327,309 (-)NCBICHM1_1
T2T-CHM13v2.0X71,645,741 - 71,648,293 (-)NCBIT2T-CHM13v2.0
Nap1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X102,227,782 - 102,230,259 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX102,227,782 - 102,230,246 (-)EnsemblGRCm39 Ensembl
GRCm38X103,184,176 - 103,186,653 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX103,184,176 - 103,186,640 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X100,379,398 - 100,382,003 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X99,386,895 - 99,389,359 (-)NCBIMGSCv36mm8
CeleraX90,080,644 - 90,083,249 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX45.97NCBI
NAP1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X72,877,617 - 72,880,206 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X72,881,225 - 72,883,778 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X62,447,064 - 62,449,612 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X72,569,682 - 72,572,257 (-)NCBIpanpan1.1PanPan1.1panPan2
NAP1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X57,085,962 - 57,088,235 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX57,086,769 - 57,088,157 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX48,262,999 - 48,265,284 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X58,296,278 - 58,298,563 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X56,043,322 - 56,045,607 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X57,621,314 - 57,623,599 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X57,155,056 - 57,157,341 (-)NCBIUU_Cfam_GSD_1.0
Nap1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X44,819,564 - 44,822,126 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936683126,425 - 127,801 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936683125,645 - 128,213 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100525798
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX58,966,830 - 58,972,091 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X58,969,577 - 59,176,807 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X66,688,054 - 66,690,620 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAP1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X62,792,375 - 62,794,954 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX62,793,164 - 62,794,540 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660654,713,761 - 4,716,032 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Nap1l2
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:80
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000004038
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat

Markers in Region
X92352  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X68,174,401 - 68,174,590 (+)MAPPERmRatBN7.2
Rnor_6.0X73,997,630 - 73,997,818NCBIRnor6.0
Rnor_5.0X74,802,525 - 74,802,713UniSTSRnor5.0
RGSC_v3.4X91,128,191 - 91,128,379UniSTSRGSC3.4
CeleraX69,542,575 - 69,542,763UniSTS
Cytogenetic MapXq31UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004038   ⟹   ENSRNOP00000078092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX68,173,987 - 68,176,666 (-)Ensembl
Rnor_6.0 EnsemblX73,998,034 - 73,999,419 (-)Ensembl
RefSeq Acc Id: NM_001024789   ⟹   NP_001019960
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X72,239,849 - 72,242,247 (-)NCBI
mRatBN7.2X68,174,051 - 68,176,449 (-)NCBI
Rnor_6.0X73,997,274 - 73,999,677 (-)NCBI
Rnor_5.0X74,802,169 - 74,804,572 (-)NCBI
RGSC_v3.4X91,127,838 - 91,130,238 (-)RGD
CeleraX69,542,224 - 69,544,622 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001019960 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH94525 (Get FASTA)   NCBI Sequence Viewer  
  EDM07195 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078092
  ENSRNOP00000078092.1
Reference Protein Sequences
RefSeq Acc Id: NP_001019960   ⟸   NM_001024789
- UniProtKB: Q505I8 (UniProtKB/TrEMBL),   A6IUY6 (UniProtKB/TrEMBL),   A0A8I5YCM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000078092   ⟸   ENSRNOT00000004038

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563260 AgrOrtholog
BioCyc Gene G2FUF-2041 BioCyc
Ensembl Genes ENSRNOG00000003025 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004038 ENTREZGENE
  ENSRNOT00000004038.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1500 UniProtKB/TrEMBL
  Nucleosome assembly protein UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7318126 IMAGE-MGC_LOAD
InterPro NAP-like_sf UniProtKB/TrEMBL
  NAP_family UniProtKB/TrEMBL
KEGG Report rno:317247 UniProtKB/TrEMBL
MGC_CLONE MGC:105621 IMAGE-MGC_LOAD
NCBI Gene 317247 ENTREZGENE
PANTHER NAP_family UniProtKB/TrEMBL
  NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 2 UniProtKB/TrEMBL
Pfam NAP UniProtKB/TrEMBL
PhenoGen Nap1l2 PhenoGen
RatGTEx ENSRNOG00000003025 RatGTEx
Superfamily-SCOP SSF143113 UniProtKB/TrEMBL
UniProt A0A8I5YCM6 ENTREZGENE, UniProtKB/TrEMBL
  A6IUY6 ENTREZGENE, UniProtKB/TrEMBL
  Q505I8 ENTREZGENE
UniProt Secondary Q505I8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Nap1l2  nucleosome assembly protein 1-like 2  LOC317247  similar to Nap1l2  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC317247  similar to Nap1l2      Symbol and Name status set to provisional 70820 PROVISIONAL