Pxylp1 (2-phosphoxylose phosphatase 1) - Rat Genome Database

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Gene: Pxylp1 (2-phosphoxylose phosphatase 1) Rattus norvegicus
Analyze
Symbol: Pxylp1
Name: 2-phosphoxylose phosphatase 1
RGD ID: 1359617
Description: Predicted to enable phosphatase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process; and positive regulation of heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human PXYLP1 (2-phosphoxylose phosphatase 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acid phosphatase-like 2; acid phosphatase-like protein 2; Acpl2; MGC94167; similar to RIKEN cDNA C130099A20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88106,299,303 - 106,364,603 (-)NCBIGRCr8
mRatBN7.2897,419,766 - 97,485,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl897,419,776 - 97,485,064 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8103,088,821 - 103,154,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08101,288,077 - 101,353,418 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0899,127,032 - 99,192,374 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08104,724,728 - 104,790,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8104,724,743 - 104,790,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08104,171,280 - 104,237,228 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48101,917,842 - 101,983,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18101,937,297 - 102,002,613 (-)NCBI
Celera896,861,823 - 96,926,746 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
indometacin  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi apparatus  (IBA,ISO,ISS)
Golgi membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. null JRS Domain-based curation
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:24425863  


Genomics

Comparative Map Data
Pxylp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88106,299,303 - 106,364,603 (-)NCBIGRCr8
mRatBN7.2897,419,766 - 97,485,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl897,419,776 - 97,485,064 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8103,088,821 - 103,154,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08101,288,077 - 101,353,418 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0899,127,032 - 99,192,374 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08104,724,728 - 104,790,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8104,724,743 - 104,790,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08104,171,280 - 104,237,228 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48101,917,842 - 101,983,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18101,937,297 - 102,002,613 (-)NCBI
Celera896,861,823 - 96,926,746 (-)NCBICelera
Cytogenetic Map8q31NCBI
PXYLP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383141,231,825 - 141,294,924 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3141,228,726 - 141,367,753 (+)EnsemblGRCh38hg38GRCh38
GRCh373140,950,667 - 141,013,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363142,433,372 - 142,496,176 (+)NCBINCBI36Build 36hg18NCBI36
Build 343142,433,400 - 142,496,173NCBI
Celera3139,374,122 - 139,436,924 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3138,325,840 - 138,388,459 (+)NCBIHuRef
CHM1_13140,913,654 - 140,976,290 (+)NCBICHM1_1
T2T-CHM13v2.03143,979,382 - 144,042,517 (+)NCBIT2T-CHM13v2.0
Pxylp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39996,705,396 - 96,774,732 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl996,705,389 - 96,774,722 (-)EnsemblGRCm39 Ensembl
GRCm38996,823,336 - 96,892,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl996,823,336 - 96,892,669 (-)EnsemblGRCm38mm10GRCm38
MGSCv37996,723,762 - 96,789,841 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36996,632,695 - 96,698,774 (-)NCBIMGSCv36mm8
Celera996,382,737 - 96,449,124 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.71NCBI
Pxylp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555084,390,455 - 4,449,782 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555084,390,647 - 4,449,782 (-)NCBIChiLan1.0ChiLan1.0
PXYLP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22139,141,292 - 139,204,377 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13139,146,024 - 139,209,109 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03138,264,529 - 138,327,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13145,862,427 - 145,925,073 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3145,864,356 - 145,925,073 (+)Ensemblpanpan1.1panPan2
PXYLP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12337,145,065 - 37,197,808 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2337,145,086 - 37,196,427 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2337,118,960 - 37,191,465 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02337,656,780 - 37,729,280 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2337,656,844 - 37,729,266 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12337,339,109 - 37,411,612 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02337,417,071 - 37,489,492 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02337,659,659 - 37,732,146 (+)NCBIUU_Cfam_GSD_1.0
Pxylp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560276,335,793 - 76,393,785 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365403,075,624 - 3,135,182 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365403,075,618 - 3,133,554 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PXYLP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1381,970,447 - 82,046,028 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11381,951,336 - 82,049,385 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21389,793,696 - 89,886,110 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PXYLP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11549,307,124 - 49,369,961 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1549,306,714 - 49,341,565 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604122,249,609 - 22,313,996 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pxylp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473017,845,851 - 17,928,280 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473017,845,818 - 17,928,021 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pxylp1
297 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:320
Count of miRNA genes:204
Interacting mature miRNAs:251
Transcripts:ENSRNOT00000017085
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat

Markers in Region
RH135344  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2897,457,987 - 97,458,180 (+)MAPPERmRatBN7.2
Rnor_6.08104,762,963 - 104,763,155NCBIRnor6.0
Rnor_5.08104,209,522 - 104,209,714UniSTSRnor5.0
RGSC_v3.48101,956,075 - 101,956,267UniSTSRGSC3.4
Celera896,899,656 - 96,899,848UniSTS
RH 3.4 Map81058.5UniSTS
Cytogenetic Map8q31UniSTS
RH137269  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2897,419,828 - 97,420,048 (+)MAPPERmRatBN7.2
Rnor_6.08104,724,798 - 104,725,017NCBIRnor6.0
Rnor_5.08104,171,350 - 104,171,569UniSTSRnor5.0
RGSC_v3.48101,917,898 - 101,918,117UniSTSRGSC3.4
Celera896,861,879 - 96,862,098UniSTS
RH 3.4 Map81058.5UniSTS
Cytogenetic Map8q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 31 22 14 19 14 73 34 40 10
Low 12 35 27 27 8 11 1 1 1 1 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000017085   ⟹   ENSRNOP00000017085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl897,419,787 - 97,485,064 (-)Ensembl
Rnor_6.0 Ensembl8104,724,743 - 104,790,639 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115781   ⟹   ENSRNOP00000093431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl897,419,776 - 97,436,530 (-)Ensembl
RefSeq Acc Id: NM_001007710   ⟹   NP_001007711
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,364,603 (-)NCBI
mRatBN7.2897,419,773 - 97,485,075 (-)NCBI
Rnor_6.08104,724,742 - 104,790,639 (-)NCBI
Rnor_5.08104,171,280 - 104,237,228 (-)NCBI
RGSC_v3.48101,917,842 - 101,983,158 (-)RGD
Celera896,861,823 - 96,926,746 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243591   ⟹   XP_006243653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,364,397 (-)NCBI
mRatBN7.2897,419,766 - 97,484,885 (-)NCBI
Rnor_6.08104,724,728 - 104,790,578 (-)NCBI
Rnor_5.08104,171,280 - 104,237,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243592   ⟹   XP_006243654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,344,466 (-)NCBI
mRatBN7.2897,419,766 - 97,460,814 (-)NCBI
Rnor_6.08104,724,728 - 104,763,931 (-)NCBI
Rnor_5.08104,171,280 - 104,237,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595678   ⟹   XP_017451167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,330,420 (-)NCBI
mRatBN7.2897,419,766 - 97,450,979 (-)NCBI
Rnor_6.08104,724,728 - 104,757,462 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265585   ⟹   XP_063121655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,345,022 (-)NCBI
RefSeq Acc Id: XM_063265586   ⟹   XP_063121656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,345,022 (-)NCBI
RefSeq Acc Id: XR_010053979
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,347,323 (-)NCBI
RefSeq Acc Id: XR_010053980
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,345,022 (-)NCBI
RefSeq Acc Id: XR_010053981
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,299,303 - 106,364,397 (-)NCBI
RefSeq Acc Id: NP_001007711   ⟸   NM_001007710
- UniProtKB: Q66H78 (UniProtKB/Swiss-Prot),   A0A8I6AKD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243653   ⟸   XM_006243591
- Peptide Label: isoform X1
- UniProtKB: Q66H78 (UniProtKB/Swiss-Prot),   A0A8I6AKD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243654   ⟸   XM_006243592
- Peptide Label: isoform X1
- UniProtKB: Q66H78 (UniProtKB/Swiss-Prot),   A0A8I6AKD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451167   ⟸   XM_017595678
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AKD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000017085   ⟸   ENSRNOT00000017085
RefSeq Acc Id: ENSRNOP00000093431   ⟸   ENSRNOT00000115781
RefSeq Acc Id: XP_063121655   ⟸   XM_063265585
- Peptide Label: isoform X1
- UniProtKB: Q66H78 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063121656   ⟸   XM_063265586
- Peptide Label: isoform X1
- UniProtKB: Q66H78 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H78-F1-model_v2 AlphaFold Q66H78 1-480 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696195
Promoter ID:EPDNEW_R6720
Type:initiation region
Name:Pxylp1_1
Description:2-phosphoxylose phosphatase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08104,790,667 - 104,790,727EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359617 AgrOrtholog
BioCyc Gene G2FUF-29432 BioCyc
Ensembl Genes ENSRNOG00000012480 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055017549 UniProtKB/Swiss-Prot
  ENSRNOG00060008185 UniProtKB/Swiss-Prot
  ENSRNOG00065007446 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017085 ENTREZGENE
  ENSRNOT00000017085.5 UniProtKB/Swiss-Prot
  ENSRNOT00000115781.1 UniProtKB/TrEMBL
  ENSRNOT00055029689 UniProtKB/Swiss-Prot
  ENSRNOT00060013559 UniProtKB/Swiss-Prot
  ENSRNOT00065011630 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7128571 IMAGE-MGC_LOAD
InterPro His_Pase_clade-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:315939 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94167 IMAGE-MGC_LOAD
NCBI Gene 315939 ENTREZGENE
PANTHER 2-PHOSPHOXYLOSE PHOSPHATASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACID PHOSPHATASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam His_Phos_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pxylp1 PhenoGen
RatGTEx ENSRNOG00000012480 RatGTEx
  ENSRNOG00055017549 RatGTEx
  ENSRNOG00060008185 RatGTEx
  ENSRNOG00065007446 RatGTEx
Superfamily-SCOP SSF53254 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AKD7 ENTREZGENE, UniProtKB/TrEMBL
  PXYP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-27 Pxylp1  2-phosphoxylose phosphatase 1  Acpl2  acid phosphatase-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Acpl2  acid phosphatase-like 2  MGC94167  similar to RIKEN cDNA C130099A20  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC94167  similar to RIKEN cDNA C130099A20      Symbol and Name status set to provisional 70820 PROVISIONAL