Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ARMCX2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Armcx2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARMCX2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ARMCX2 mRNA | CTD | PMID:17557909 | 17beta-estradiol | multiple interactions | ISO | ARMCX2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of ARMCX2 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Armcx2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARMCX2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARMCX2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Armcx2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARMCX2 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-methylcholine | affects expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ARMCX2 mRNA | CTD | PMID:21179406 | 4-hydroxyphenyl retinamide | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of ARMCX2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ARMCX2 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ARMCX2 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | ISO | ARMCX2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARMCX2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARMCX2 mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of ARMCX2 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ARMCX2 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ARMCX2 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ARMCX2 gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | ARMCX2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARMCX2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARMCX2 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ARMCX2 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | decreases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARMCX2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ARMCX2 mRNA | CTD | PMID:32417428 | benzo[a]pyrene | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ARMCX2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ARMCX2 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of ARMCX2 promoter | CTD | PMID:23359474 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of ARMCX2 promoter | CTD | PMID:23359474 | bisphenol A | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of ARMCX2 gene | CTD | PMID:31601247 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ARMCX2 mRNA | CTD | PMID:25181051 | cadmium sulfate | multiple interactions | ISO | Armcx2 (Mus musculus) | 6480464 | cadmium sulfate affects the reaction [MTF1 affects the expression of ARMCX2 mRNA] | CTD | PMID:16221973 | calcium silicate | decreases expression | ISO | Armcx2 (Mus musculus) | 6480464 | calcium silicate results in decreased expression of ARMCX2 mRNA | CTD | PMID:29279043 | carbon nanotube | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of ARMCX2 mRNA | CTD | PMID:25554681 | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of ARMCX2 mRNA | CTD | PMID:23125180 | chloroprene | decreases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of ARMCX2 mRNA | CTD | PMID:23125180 | cisplatin | affects response to substance | ISO | ARMCX2 (Homo sapiens) | 6480464 | ARMCX2 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | cobalt dichloride | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of ARMCX2 mRNA | CTD | PMID:19320972 | copper(II) sulfate | increases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ARMCX2 mRNA | CTD | PMID:19549813 | dibutyl phthalate | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of ARMCX2 mRNA | CTD | PMID:21266533 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of ARMCX2 promoter | CTD | PMID:23359474 | doxorubicin | increases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ARMCX2 mRNA | CTD | PMID:29803840 | fonofos | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of ARMCX2 promoter | CTD | PMID:22847954 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of ARMCX2 mRNA | CTD | PMID:27387713 | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of ARMCX2 mRNA | CTD | PMID:29933104 | iron dichloride | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of ARMCX2 mRNA | CTD | PMID:35984750 | lipopolysaccharide | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of ARMCX2 mRNA | CTD | PMID:27339419 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ARMCX2 mRNA | CTD | PMID:30047161 | nevirapine | decreases expression | EXP | | 6480464 | Nevirapine metabolite results in decreased expression of ARMCX2 mRNA and Nevirapine results in decreased expression of ARMCX2 mRNA | CTD | PMID:23947594 | nickel sulfate | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of ARMCX2 mRNA | CTD | PMID:22714537 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of ARMCX2 mRNA | CTD | PMID:25729387 | oxaliplatin | increases expression | EXP | | 6480464 | oxaliplatin results in increased expression of ARMCX2 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | ARMCX2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARMCX2 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Armcx2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ARMCX2 mRNA | CTD | PMID:17562736 | parathion | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Parathion results in increased methylation of ARMCX2 promoter | CTD | PMID:22847954 | pioglitazone | multiple interactions | ISO | Armcx2 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ARMCX2 mRNA | CTD | PMID:27935865 | pirinixic acid | multiple interactions | ISO | ARMCX2 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ARMCX2 mRNA | CTD | PMID:19710929 | potassium dichromate | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of ARMCX2 protein | CTD | PMID:23718831 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ARMCX2 mRNA | CTD | PMID:30047161 | silicon dioxide | increases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of ARMCX2 mRNA | CTD | PMID:25351596 | sodium arsenite | decreases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased methylation of ARMCX2 gene | CTD | PMID:24570342 | sodium arsenite | increases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ARMCX2 mRNA | CTD | PMID:24570342 and PMID:29301061 | sunitinib | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ARMCX2 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of ARMCX2 mRNA | CTD | PMID:31758290 | terbufos | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | terbufos results in increased methylation of ARMCX2 promoter | CTD | PMID:22847954 | tetrachloromethane | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ARMCX2 mRNA | CTD | PMID:27339419 and PMID:31919559 | titanium dioxide | decreases expression | ISO | Armcx2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ARMCX2 mRNA | CTD | PMID:29264374 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of ARMCX2 mRNA | CTD | PMID:25729387 | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of ARMCX2 mRNA | CTD | PMID:25729387 | tungsten | decreases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ARMCX2 mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | ARMCX2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ARMCX2 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | Armcx2 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ARMCX2 mRNA | CTD | PMID:21427059 | valproic acid | increases expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARMCX2 mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | ARMCX2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARMCX2 mRNA | CTD | PMID:25979313 | |