Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SDAD1 mRNA] | CTD | PMID:31150632 | (-)-alpha-phellandrene | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of SDAD1 mRNA | CTD | PMID:25075043 | 17alpha-ethynylestradiol | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of SDAD1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SDAD1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SDAD1 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Sdad1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SDAD1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SDAD1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sdad1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SDAD1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SDAD1 mRNA | CTD | PMID:17942748 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of SDAD1 mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SDAD1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SDAD1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SDAD1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SDAD1 mRNA | CTD | PMID:28628672 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of SDAD1 mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SDAD1 mRNA | CTD | PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of SDAD1 mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SDAD1 mRNA | CTD | PMID:33167477 | alpha-phellandrene | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of SDAD1 mRNA | CTD | PMID:25075043 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SDAD1 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SDAD1 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of SDAD1 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SDAD1 mRNA | CTD | PMID:20127859 | bis(2-chloroethyl) sulfide | increases phosphorylation | ISO | SDAD1 (Homo sapiens) | 6480464 | Mustard Gas results in increased phosphorylation of SDAD1 protein | CTD | PMID:19845377 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SDAD1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol F | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SDAD1 mRNA | CTD | PMID:28628672 | cadmium atom | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SDAD1 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SDAD1 mRNA | CTD | PMID:37325564 | carbon nanotube | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of SDAD1 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SDAD1 gene] | CTD | PMID:28238834 | chromium(6+) | affects expression | ISO | Sdad1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of SDAD1 mRNA | CTD | PMID:28472532 | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of SDAD1 mRNA | CTD | PMID:17898221 | crocidolite asbestos | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of SDAD1 mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SDAD1 mRNA | CTD | PMID:20106945 and PMID:25562108 | dexamethasone | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SDAD1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SDAD1 mRNA | CTD | PMID:28628672 | diethylstilbestrol | increases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of SDAD1 mRNA | CTD | PMID:36621641 | dioxygen | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SDAD1 mRNA | CTD | PMID:30529165 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SDAD1 mRNA | CTD | PMID:29391264 | fluoranthene | multiple interactions | ISO | Sdad1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of SDAD1 mRNA | CTD | PMID:28329830 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SDAD1 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SDAD1 mRNA | CTD | PMID:25629700 | FR900359 | increases phosphorylation | ISO | SDAD1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SDAD1 protein | CTD | PMID:37730182 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SDAD1 mRNA | CTD | PMID:25539665 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SDAD1 mRNA | CTD | PMID:22061828 | indometacin | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SDAD1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SDAD1 mRNA | CTD | PMID:28628672 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SDAD1 mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SDAD1 gene | CTD | PMID:35440735 | nickel atom | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of SDAD1 mRNA | CTD | PMID:23195993 | ozone | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of SDAD1 mRNA | CTD | PMID:35430440 | p-chloromercuribenzoic acid | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of SDAD1 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | Sdad1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SDAD1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SDAD1 mRNA | CTD | PMID:21420995 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of SDAD1 mRNA | CTD | PMID:32680482 | pentachlorophenol | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of SDAD1 mRNA | CTD | PMID:23892564 | pirinixic acid | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SDAD1 mRNA | CTD | PMID:23811191 | resveratrol | multiple interactions | ISO | SDAD1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SDAD1 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of SDAD1 mRNA | CTD | PMID:23557933 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of SDAD1 mRNA | CTD | PMID:25993096 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of SDAD1 mRNA | CTD | PMID:19281266 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SDAD1 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | SDAD1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SDAD1 mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SDAD1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SDAD1 mRNA | CTD | PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SDAD1 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SDAD1 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | ISO | Sdad1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SDAD1 mRNA | CTD | PMID:27760801 | triptonide | decreases expression | ISO | Sdad1 (Mus musculus) | 6480464 | triptonide results in decreased expression of SDAD1 mRNA | CTD | PMID:33045310 | valproic acid | decreases methylation | ISO | SDAD1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SDAD1 gene | CTD | PMID:29154799 | |