Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of SEC62 mRNA | CTD | PMID:23649840 | 1,1-dichloroethene | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of SEC62 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SEC62 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | SEC62 (Homo sapiens) | 6480464 | Estradiol affects the expression of SEC62 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sec62 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SEC62 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SEC62 mRNA | CTD | PMID:34747641 | 2-hydroxypropanoic acid | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEC62 mRNA | CTD | PMID:30851411 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Sec62 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of SEC62 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Sec62 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of SEC62 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of SEC62 protein | CTD | PMID:34186270 | aflatoxin B1 | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of SEC62 mRNA | CTD | PMID:21641981 | aflatoxin B1 | decreases methylation | ISO | SEC62 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SEC62 gene | CTD | PMID:27153756 | aldehydo-D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of SEC62 protein | CTD | PMID:34801538 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of SEC62 protein] and Metformin inhibits the reaction [Glucose results in increased expression of SEC62 protein] | CTD | PMID:34801538 | all-trans-retinoic acid | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SEC62 mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SEC62 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SEC62 protein | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of SEC62 mRNA | CTD | PMID:23650126 | arsane | increases ubiquitination | ISO | SEC62 (Homo sapiens) | 6480464 | Arsenic results in increased ubiquitination of SEC62 protein | CTD | PMID:35994080 | arsenic atom | increases ubiquitination | ISO | SEC62 (Homo sapiens) | 6480464 | Arsenic results in increased ubiquitination of SEC62 protein | CTD | PMID:35994080 | arsenite(3-) | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SEC62 mRNA] | CTD | PMID:32406909 | arsenous acid | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of SEC62 mRNA | CTD | PMID:35676786 | atrazine | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SEC62 mRNA | CTD | PMID:22378314 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SEC62 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SEC62 protein | CTD | PMID:34186270 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SEC62 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SEC62 mRNA | CTD | PMID:33221593 | bisphenol F | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of SEC62 protein | CTD | PMID:34186270 | butanal | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SEC62 mRNA | CTD | PMID:26079696 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of SEC62 mRNA | CTD | PMID:33453195 | carbon nanotube | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlordecone | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of SEC62 mRNA | CTD | PMID:33711761 | chlorogenic acid | multiple interactions | EXP | | 6480464 | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of SEC62 protein] | CTD | PMID:34801538 | cisplatin | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SEC62 mRNA | CTD | PMID:19561079 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SEC62 mRNA | CTD | PMID:17602206 | copper atom | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of SEC62 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of SEC62 mRNA | CTD | PMID:20971185 | copper(II) sulfate | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SEC62 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of SEC62 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SEC62 mRNA | CTD | PMID:25562108 | D-glucose | multiple interactions | EXP | | 6480464 | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of SEC62 protein] and Metformin inhibits the reaction [Glucose results in increased expression of SEC62 protein] | CTD | PMID:34801538 | D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of SEC62 protein | CTD | PMID:34801538 | dextran sulfate | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of SEC62 protein | CTD | PMID:32272095 | dextran sulfate | multiple interactions | ISO | Sec62 (Mus musculus) | 6480464 | Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SEC62 protein] | CTD | PMID:32272095 | diarsenic trioxide | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of SEC62 mRNA | CTD | PMID:35676786 | dicrotophos | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SEC62 mRNA | CTD | PMID:28302478 | dioxygen | affects methylation | ISO | Sec62 (Mus musculus) | 6480464 | Oxygen deficiency affects the methylation of SEC62 promoter | CTD | PMID:24205000 | dioxygen | increases expression | ISO | Sec62 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of SEC62 mRNA | CTD | PMID:24205000 | dorsomorphin | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEC62 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of SEC62 mRNA | CTD | PMID:29803840 | elemental selenium | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Selenium results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | elemental selenium | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | ethanol | multiple interactions | ISO | Sec62 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of SEC62 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SEC62 mRNA | CTD | PMID:23649840 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of SEC62 mRNA | CTD | PMID:24136188 | folic acid | increases expression | ISO | Sec62 (Mus musculus) | 6480464 | Folic Acid results in increased expression of SEC62 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SEC62 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | SEC62 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SEC62 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SEC62 mRNA | CTD | PMID:22061828 | glucose | multiple interactions | EXP | | 6480464 | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of SEC62 protein] and Metformin inhibits the reaction [Glucose results in increased expression of SEC62 protein] | CTD | PMID:34801538 | glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of SEC62 protein | CTD | PMID:34801538 | kojic acid | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of SEC62 mRNA | CTD | PMID:16595896 | metformin | multiple interactions | EXP | | 6480464 | Metformin inhibits the reaction [Glucose results in increased expression of SEC62 protein] | CTD | PMID:34801538 | methyl methanesulfonate | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SEC62 mRNA | CTD | PMID:23649840 | miconazole | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Miconazole results in decreased expression of SEC62 mRNA | CTD | PMID:27462272 | mifepristone | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Mifepristone results in increased expression of SEC62 mRNA | CTD | PMID:17584828 | mono(2-ethylhexyl) phthalate | decreases methylation | ISO | Sec62 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased methylation of SEC62 mRNA | CTD | PMID:31875672 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SEC62 mRNA | CTD | PMID:17602206 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of SEC62 mRNA | CTD | PMID:24136188 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of SEC62 protein | CTD | PMID:33146391 | paracetamol | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SEC62 mRNA | CTD | PMID:21420995 | pentanal | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | pentanal results in decreased expression of SEC62 mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SEC62 mRNA | CTD | PMID:27153767 | phenobarbital | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of SEC62 mRNA | CTD | PMID:19363144 | phenobarbital | affects expression | ISO | Sec62 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SEC62 mRNA | CTD | PMID:23091169 | picoxystrobin | increases expression | ISO | SEC62 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of SEC62 mRNA | CTD | PMID:33512557 | potassium dichromate | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of SEC62 protein | CTD | PMID:23718831 | potassium dichromate | increases expression | ISO | Sec62 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of SEC62 mRNA | CTD | PMID:23608068 | progesterone | affects expression | ISO | Sec62 (Mus musculus) | 6480464 | Progesterone affects the expression of SEC62 mRNA | CTD | PMID:17251523 | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of SEC62 mRNA | CTD | PMID:21565894 | rac-lactic acid | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEC62 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SEC62 mRNA | CTD | PMID:23557933 | rimonabant | multiple interactions | ISO | Sec62 (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA] | CTD | PMID:19030233 | SB 431542 | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEC62 mRNA | CTD | PMID:27188386 | selenium atom | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Selenium results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | selenium atom | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SEC62 mRNA | CTD | PMID:25895662 | sodium arsenate | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of SEC62 mRNA | CTD | PMID:30953684 | sodium arsenite | affects expression | ISO | SEC62 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of SEC62 mRNA | CTD | PMID:29319823 | sulindac | decreases expression | EXP | | 6480464 | Sulindac results in decreased expression of SEC62 mRNA | CTD | PMID:24136188 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SEC62 mRNA | CTD | PMID:34492290 | trichostatin A | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SEC62 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEC62 mRNA | CTD | PMID:27188386 | triptonide | increases expression | ISO | Sec62 (Mus musculus) | 6480464 | triptonide results in increased expression of SEC62 mRNA | CTD | PMID:33045310 | tungsten | decreases expression | ISO | Sec62 (Mus musculus) | 6480464 | Tungsten results in decreased expression of SEC62 mRNA | CTD | PMID:30912803 | uranium atom | affects expression | ISO | SEC62 (Homo sapiens) | 6480464 | Uranium affects the expression of SEC62 mRNA | CTD | PMID:15672453 | valproic acid | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SEC62 mRNA | CTD | PMID:23179753 and PMID:24383497 | vincristine | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of SEC62 mRNA | CTD | PMID:23649840 | vitamin E | decreases expression | ISO | SEC62 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | vitamin E | multiple interactions | ISO | SEC62 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SEC62 mRNA | CTD | PMID:19244175 | |