Tekt5 (tektin 5) - Rat Genome Database

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Gene: Tekt5 (tektin 5) Rattus norvegicus
Analyze
Symbol: Tekt5
Name: tektin 5
RGD ID: 1307081
Description: Predicted to be involved in cilium assembly and cilium movement involved in cell motility. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human TEKT5 (tektin 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363538; RGD1307081; similar to hypothetical protein FLJ32871; Tek5; tektin-5; Tektin5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,786,656 - 5,823,411 (+)NCBIGRCr8
mRatBN7.2105,279,856 - 5,316,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl105,279,893 - 5,316,619 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,976,169 - 10,012,923 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,497,282 - 9,534,042 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0105,135,661 - 5,172,393 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0105,353,007 - 5,389,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl105,352,933 - 5,389,737 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0104,175,075 - 4,211,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4105,230,620 - 5,267,737 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1105,230,547 - 5,267,791 (+)NCBI
Celera104,296,501 - 4,332,868 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:17924527   PMID:20378928   PMID:21630459  


Genomics

Comparative Map Data
Tekt5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,786,656 - 5,823,411 (+)NCBIGRCr8
mRatBN7.2105,279,856 - 5,316,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl105,279,893 - 5,316,619 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,976,169 - 10,012,923 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,497,282 - 9,534,042 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0105,135,661 - 5,172,393 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0105,353,007 - 5,389,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl105,352,933 - 5,389,737 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0104,175,075 - 4,211,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4105,230,620 - 5,267,737 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1105,230,547 - 5,267,791 (+)NCBI
Celera104,296,501 - 4,332,868 (+)NCBICelera
Cytogenetic Map10q11NCBI
TEKT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381610,627,501 - 10,694,930 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1610,627,501 - 10,694,930 (-)EnsemblGRCh38hg38GRCh38
GRCh371610,721,358 - 10,788,787 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361610,628,862 - 10,696,303 (-)NCBINCBI36Build 36hg18NCBI36
Celera1610,890,682 - 10,958,126 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1610,640,232 - 10,707,936 (-)NCBIHuRef
CHM1_11610,721,348 - 10,788,815 (-)NCBICHM1_1
T2T-CHM13v2.01610,663,431 - 10,730,854 (-)NCBIT2T-CHM13v2.0
Tekt5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,175,816 - 10,213,319 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,175,812 - 10,213,354 (-)EnsemblGRCm39 Ensembl
GRCm381610,357,952 - 10,395,455 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,357,948 - 10,395,490 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,361,347 - 10,395,541 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,271,529 - 10,309,033 (-)NCBIMGSCv36mm8
Celera1610,995,024 - 11,029,499 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.58NCBI
Tekt5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,740,540 - 7,778,245 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,740,611 - 7,778,130 (+)NCBIChiLan1.0ChiLan1.0
TEKT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21811,165,093 - 11,240,717 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11614,941,029 - 15,016,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0169,558,028 - 9,634,095 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11610,785,384 - 10,858,712 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1610,790,966 - 10,858,711 (-)Ensemblpanpan1.1panPan2
TEKT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,936,574 - 31,976,260 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,936,653 - 31,976,183 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha633,318,947 - 33,358,644 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0632,119,007 - 32,158,798 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl632,119,098 - 32,158,721 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,933,027 - 31,972,719 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,806,958 - 31,846,721 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0632,231,128 - 32,270,930 (+)NCBIUU_Cfam_GSD_1.0
Tekt5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,080,088 - 111,114,520 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365308,925,691 - 8,959,815 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365308,925,593 - 8,959,849 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEKT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl332,350,906 - 32,393,337 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1332,350,906 - 32,393,123 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2333,149,378 - 33,194,161 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TEKT5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,106,537 - 10,172,758 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,106,400 - 10,172,237 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,987,907 - 20,054,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tekt5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248247,966,510 - 8,010,592 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248247,961,590 - 8,024,640 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tekt5
259 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:40
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000003465
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1549898Neuinf3Neuroinflammation QTL 326.4nervous system integrity trait (VT:0010566)MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio (CMO:0001980)1034063205387112Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat

Markers in Region
D10Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2105,304,796 - 5,304,932 (+)MAPPERmRatBN7.2
Rnor_6.0105,377,916 - 5,378,049NCBIRnor6.0
Rnor_5.0104,199,884 - 4,200,017UniSTSRnor5.0
RGSC_v3.4105,255,289 - 5,255,420RGDRGSC3.4
RGSC_v3.4105,255,290 - 5,255,423UniSTSRGSC3.4
RGSC_v3.1105,255,289 - 5,255,420RGD
RH 2.0 Map100.0RGD
Cytogenetic Map10q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 6 42 7 3 11
Below cutoff 2 25 15 9 11 9 5 7 26 28 25 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003465   ⟹   ENSRNOP00000003465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl105,279,893 - 5,316,619 (+)Ensembl
Rnor_6.0 Ensembl105,352,933 - 5,389,737 (+)Ensembl
RefSeq Acc Id: NM_001014224   ⟹   NP_001014246
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8105,786,656 - 5,823,411 (+)NCBI
mRatBN7.2105,279,856 - 5,316,619 (+)NCBI
Rnor_6.0105,353,007 - 5,389,684 (+)NCBI
Rnor_5.0104,175,075 - 4,211,652 (+)NCBI
RGSC_v3.4105,230,620 - 5,267,737 (+)RGD
Celera104,296,501 - 4,332,868 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001014246 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79040 (Get FASTA)   NCBI Sequence Viewer  
  BAF57906 (Get FASTA)   NCBI Sequence Viewer  
  EDL96225 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003465
  ENSRNOP00000003465.4
Reference Protein Sequences
RefSeq Acc Id: NP_001014246   ⟸   NM_001014224
- UniProtKB: Q6AYH7 (UniProtKB/TrEMBL),   A6K4K3 (UniProtKB/TrEMBL),   F7F3Q2 (UniProtKB/TrEMBL),   A4UY00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003465   ⟸   ENSRNOT00000003465

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYH7-F1-model_v2 AlphaFold Q6AYH7 1-558 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696946
Promoter ID:EPDNEW_R7471
Type:multiple initiation site
Name:Tekt5_1
Description:tektin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0105,352,970 - 5,353,030EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307081 AgrOrtholog
BioCyc Gene G2FUF-26128 BioCyc
Ensembl Genes ENSRNOG00000002571 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003465 ENTREZGENE
  ENSRNOT00000003465.5 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114771 IMAGE-MGC_LOAD
InterPro Tektin UniProtKB/TrEMBL
  Tektin-like UniProtKB/TrEMBL
KEGG Report rno:363538 UniProtKB/TrEMBL
MGC_CLONE MGC:93973 IMAGE-MGC_LOAD
NCBI Gene 363538 ENTREZGENE
PANTHER PTHR19960 UniProtKB/TrEMBL
  TEKTIN-5 UniProtKB/TrEMBL
Pfam Tektin UniProtKB/TrEMBL
PhenoGen Tekt5 PhenoGen
PRINTS TEKTIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002571 RatGTEx
UniProt A4UY00 ENTREZGENE, UniProtKB/TrEMBL
  A6K4K3 ENTREZGENE, UniProtKB/TrEMBL
  F7F3Q2 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYH7 ENTREZGENE
UniProt Secondary Q6AYH7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Tekt5  tektin 5  RGD1307081  similar to hypothetical protein FLJ32871  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1307081  similar to hypothetical protein FLJ32871  RGD1307081_predicted  similar to hypothetical protein FLJ32871 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307081_predicted  similar to hypothetical protein FLJ32871 (predicted)  LOC363538_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363538_predicted  similar to hypothetical protein FLJ32871 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL