Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NEURL2 mRNA] | CTD | PMID:31150632 | 1,2-dichloroethane | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of NEURL2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of NEURL2 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of NEURL2 mRNA | CTD | PMID:30723492 | 17beta-estradiol | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of NEURL2 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NEURL2 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NEURL2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NEURL2 mRNA | CTD | PMID:20702594 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NEURL2 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NEURL2 mRNA | CTD | PMID:21215274 | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:20702594 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Neurl2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of NEURL2 promoter | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of NEURL2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of NEURL2 mRNA | CTD | PMID:24780913 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of NEURL2 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of NEURL2 mRNA | CTD | PMID:21641981 | antirheumatic drug | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of NEURL2 mRNA | CTD | PMID:24449571 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of NEURL2 mRNA | CTD | PMID:36841081 | benzo[a]pyrene | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NEURL2 mRNA | CTD | PMID:20106945 more ... | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NEURL2 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NEURL2 mRNA | CTD | PMID:30816183 and PMID:32528016 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of NEURL2 promoter | CTD | PMID:22457795 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of NEURL2 mRNA | CTD | PMID:33453195 | cantharidin | decreases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of NEURL2 mRNA | CTD | PMID:36907384 | carbon nanotube | decreases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of NEURL2 mRNA | CTD | PMID:25554681 | chlorpyrifos | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of NEURL2 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | NEURL2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NEURL2 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NEURL2 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of NEURL2 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NEURL2 mRNA | CTD | PMID:25562108 | doxorubicin | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of NEURL2 mRNA | CTD | PMID:29803840 | ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of NEURL2 mRNA | CTD | PMID:17347304 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of NEURL2 mRNA | CTD | PMID:31881178 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of NEURL2 mRNA | CTD | PMID:33387578 | mercury dichloride | decreases expression | EXP | | 6480464 | Mercuric Chloride results in decreased expression of NEURL2 mRNA | CTD | PMID:16507785 | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA | CTD | PMID:19564919 | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of NEURL2 mRNA | CTD | PMID:19564919 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | decreases expression | ISO | Neurl2 (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NEURL2 mRNA | CTD | PMID:25566086 | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Neurl2 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of NEURL2 mRNA | CTD | PMID:27776689 | nickel atom | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Nickel results in increased expression of NEURL2 mRNA | CTD | PMID:24768652 and PMID:25583101 | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of NEURL2 mRNA | CTD | PMID:37162024 | ochratoxin A | increases methylation | EXP | | 6480464 | ochratoxin A results in increased methylation of NEURL2 gene | CTD | PMID:37162024 | phenobarbital | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of NEURL2 mRNA | CTD | PMID:19136022 | pirinixic acid | multiple interactions | ISO | Neurl2 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NEURL2 mRNA and PPARA protein affects the reaction [pirinixic acid results in increased expression of NEURL2 mRNA] | CTD | PMID:19710929 and PMID:21318169 | pirinixic acid | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NEURL2 mRNA | CTD | PMID:18301758 more ... | pirinixic acid | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | pirinixic acid affects the expression of NEURL2 mRNA | CTD | PMID:19136022 | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA | CTD | PMID:19564919 | SCH 23390 | decreases expression | EXP | | 6480464 | SCH 23390 results in decreased expression of NEURL2 mRNA | CTD | PMID:19564919 | sodium arsenite | decreases expression | ISO | Neurl2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NEURL2 mRNA | CTD | PMID:37682722 | sodium fluoride | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of NEURL2 mRNA | CTD | PMID:27862939 | sunitinib | increases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of NEURL2 mRNA | CTD | PMID:31533062 | tetrachloromethane | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of NEURL2 mRNA | CTD | PMID:17484886 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NEURL2 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NEURL2 mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NEURL2 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of NEURL2 mRNA | CTD | PMID:33387578 | triclosan | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of NEURL2 mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | Neurl2 (Mus musculus) | 6480464 | triptonide results in increased expression of NEURL2 mRNA | CTD | PMID:33045310 | urethane | decreases expression | ISO | NEURL2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of NEURL2 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Neurl2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of NEURL2 mRNA | CTD | PMID:17963808 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of NEURL2 mRNA | CTD | PMID:23034163 | |