Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APBB1IP mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of APBB1IP mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of APBB1IP mRNA | CTD | PMID:25380136 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APBB1IP mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APBB1IP mRNA | CTD | PMID:34747641 | 2,4,6-trinitrobenzenesulfonic acid | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA | CTD | PMID:17982090 | 2-palmitoylglycerol | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of APBB1IP mRNA | CTD | PMID:37199045 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of APBB1IP mRNA | CTD | PMID:20188158 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of APBB1IP mRNA | CTD | PMID:28522335 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of APBB1IP mRNA | CTD | PMID:25380136 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of APBB1IP mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | bisphenol S results in increased expression of APBB1IP mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | bisphenol S results in increased expression of APBB1IP protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of APBB1IP mRNA | CTD | PMID:24780913 | 8-Br-cAMP | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of APBB1IP mRNA | CTD | PMID:22079614 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of APBB1IP mRNA | CTD | PMID:31881176 | aflatoxin B1 | affects expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of APBB1IP protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of APBB1IP intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of APBB1IP intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Tretinoin results in increased expression of APBB1IP mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of APBB1IP mRNA | CTD | PMID:24449571 | arsenite(3-) | increases methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | arsenite results in increased methylation of APBB1IP promoter | CTD | PMID:23974009 | arsenous acid | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of APBB1IP mRNA | CTD | PMID:20458559 | benzo[a]pyrene | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of APBB1IP mRNA | CTD | PMID:20064835 and PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of APBB1IP promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of APBB1IP 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of APBB1IP mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of APBB1IP mRNA | CTD | PMID:22316170 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of APBB1IP mRNA | CTD | PMID:24988533 more ... | bisphenol A | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | bisphenol A results in increased expression of APBB1IP mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of APBB1IP gene | CTD | PMID:31601247 | bisphenol A | decreases methylation | ISO | APBB1IP (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of APBB1IP gene | CTD | PMID:31601247 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of APBB1IP mRNA | CTD | PMID:25181051 | Bisphenol B | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | bisphenol B results in increased expression of APBB1IP protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | bisphenol F results in increased expression of APBB1IP protein | CTD | PMID:34186270 | buta-1,3-diene | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of APBB1IP mRNA | CTD | PMID:29038090 | butanal | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of APBB1IP mRNA | CTD | PMID:26079696 | CGP 52608 | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to APBB1IP gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APBB1IP mRNA | CTD | PMID:20938992 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of APBB1IP mRNA | CTD | PMID:27523638 | cyclosporin A | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of APBB1IP mRNA | CTD | PMID:20106945 | diarsenic trioxide | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of APBB1IP mRNA | CTD | PMID:20458559 | diquat | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Diquat results in decreased expression of APBB1IP mRNA | CTD | PMID:36851058 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of APBB1IP mRNA | CTD | PMID:21551480 and PMID:25152437 | dorsomorphin | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APBB1IP mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Ethanol results in increased expression of APBB1IP mRNA | CTD | PMID:30319688 | ethanol | affects expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Ethanol affects the expression of APBB1IP mRNA | CTD | PMID:30319688 | ethylparaben | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of APBB1IP mRNA | CTD | PMID:37690743 | folic acid | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | formaldehyde | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of APBB1IP mRNA | CTD | PMID:27905399 | fulvestrant | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of APBB1IP gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of APBB1IP mRNA | CTD | PMID:22061828 | ivermectin | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of APBB1IP protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APBB1IP mRNA | CTD | PMID:20938992 | lipopolysaccharide | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of APBB1IP mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of APBB1IP gene | CTD | PMID:35440735 | N(4)-hydroxycytidine | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of APBB1IP mRNA | CTD | PMID:37748715 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of APBB1IP mRNA | CTD | PMID:25380136 | nickel atom | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Nickel results in increased expression of APBB1IP mRNA | CTD | PMID:25583101 | O-methyleugenol | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of APBB1IP mRNA | CTD | PMID:32234424 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APBB1IP mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of APBB1IP mRNA | CTD | PMID:34911549 | paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel results in increased expression of APBB1IP mRNA | CTD | PMID:18754875 | paracetamol | affects expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Acetaminophen affects the expression of APBB1IP mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of APBB1IP mRNA | CTD | PMID:21420995 and PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Apbb1ip (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APBB1IP mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Phenobarbital affects the expression of APBB1IP mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of APBB1IP mRNA | CTD | PMID:19710929 | potassium chromate | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of APBB1IP mRNA | CTD | PMID:22714537 | potassium dichromate | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of APBB1IP mRNA | CTD | PMID:23608068 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APBB1IP mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of APBB1IP mRNA | CTD | PMID:32721576 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of APBB1IP mRNA | CTD | PMID:19281266 | sulforaphane | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of APBB1IP mRNA | CTD | PMID:31838189 | temozolomide | decreases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of APBB1IP mRNA | CTD | PMID:31758290 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of APBB1IP mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | titanium dioxide results in increased expression of APBB1IP mRNA | CTD | PMID:23557971 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APBB1IP mRNA | CTD | PMID:25729387 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of APBB1IP mRNA | CTD | PMID:25729387 | tungsten | decreases expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Tungsten results in decreased expression of APBB1IP mRNA | CTD | PMID:30912803 | valproic acid | affects expression | ISO | Apbb1ip (Mus musculus) | 6480464 | Valproic Acid affects the expression of APBB1IP mRNA | CTD | PMID:17292431 | valproic acid | multiple interactions | ISO | APBB1IP (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APBB1IP mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | APBB1IP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of APBB1IP mRNA | CTD | PMID:23179753 more ... | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of APBB1IP mRNA | CTD | PMID:19015723 | |